14 research outputs found
Crystal structure of isobutyl 4-(2-chloro-phenyl)-5-cyano-6-{(E)-[(dimethylamino)-methylidene]amino}-2-methyl-4H-pyran-3-carboxylate
The authors thank Dr Babu Varghese, Senior Scientific Officer SAIF, IIT Madras, India, for carrying out the data collection.Peer reviewedPublisher PD
Crystal structures of salen-type ligands 2-[(1E)-({1-(3-chlorophenyl)-2-[(E)-(2-hydroxybenzylidene)amino]propyl}imino)methyl]phenol and 2-[(1E)-({1-(4-chlorophenyl)-2-[(E)-(2-hydroxybenzylidene)amino]propyl}imino)methyl]phenol
The title compounds, C23H21ClN2O2, differ from each other only by the position of the Cl atom on the corresponding benzene ring: meta relative to the central sp3 C atom for (I) and para for (II). In (I), the hydroxyphenyl rings are almost parallel, the dihedral angle between the mean planes being 9.2â
(2)°, but in (II), the relative position of the ring is different, characterized by a dihedral angle of 48.5â
(1)°. Compound (I) features intramolecular OâH...N and intermolecular CâH...O hydrogen bonds, while in (II), intramolecular OâH...N, CâH...N hydrogen bonds and weak intermolecular CâH...Ï interactions are observed. Compound (I) was refined as an inversion twin
Methyl ({[(4E)-1,3-dimethyl-2,6-diphenylpiperidin-4-ylidene]amino}oxy)acetate
In the title compound, C22H26N2O3, the piperidine ring exhibits a chair conformation. The phenyl rings attached to the piperidine at the 2- and 6-positions have axial orientations. These rings make a dihedral angle of 49.75â
(11)°. The aminooxy acetate group attached at the 4-position has an equatorial orientation. In the crystal, inversion dimers linked by pairs of CâH...Ï interactions occur
Crystal structure of (E)-1-(4âČ-methoxy-[1,1âČ-biphenyl]-4-yl)-3-(3-nitrophenyl)prop-2-en-1-one
The title compound, C22H17NO4, crystallizes with two independent molecules (A and B) in the asymmetric unit. Each molecule exists as an E isomer with CâC=CâC torsion angles of â175.69â
(17) and â178.41â
(17)° in A and B, respectively. In molecule A, the planes of the terminal benzene rings are twisted by an angle of 26.67â
(10)°, while the biphenyl unit is non-planar, the dihedral angle between the rings being 30.81â
(10)°. The dihedral angle between the nitrophenyl ring and the inner phenyl ring is 6.50â
(9)°. The corresponding values in molecule B are 60.61â
(9), 31.07â
(8) and 31.05â
(9)°. In the crystal, molecules are arranged in a head-to-head manner, with the 3-nitrophenyl groups nearly parallel to one another. The A and B molecules are linked to one another via CâH...O hydrogen bonds, forming chains lying parallel to (-320) and enclosing R22(10) and R22(12) ring motifs. The methoxy group in both molecules is positionally disordered with a refined occupancy ratio of 0.979â
(4):0.021â
(4) for molecule A and 0.55â
(4):0.45â
(4) for molecule B
Chemoselective synthesis and spectral studies of <i>N</i>-thiocyanatoacetyl derivatives of 3-alkyl-2,6-diarylpiperidin-4-ones
<p>A series of <i>N</i>âthiocyanatoacetyl derivatives of 3âalkylâ2,6âdiarylpiperidinâ4âones has been synthesized by the reaction between the <i>N</i>âchloroacetyl derivatives of the respective piperidinâ4âones and the ambident thiocyanate nucleophile. The synthesized compounds have been characterized through FTâIR, <sup>1</sup>H, <sup>13</sup>C, <sup>1</sup>Hâ<sup>1</sup>H COSY, <sup>1</sup>Hâ<sup>13</sup>C COSY and NOESY spectra. The spectral data reveal the conformational priority of the six-membered heterocyclic ring.</p