1,624 research outputs found
José Lo Giúdice
La presente tesina de licenciatura se centra en la figura del compositor argentino José Lo Giúdice (1900-1971), y se propone como objetivos principales revalorizar su figura, su producción y su accionar como gestor cultural.
Se plantea una introducción que explicita objetivos, metodología y lineamientos generales del trabajo realizado, seguido de dos partes centrales vinculadas: una reconstrucción biográfica del autor, y una descripción y fichaje del archivo familiar, que contiene documentos de relevancia histórica tales como fotografías, partituras inéditas, escritos, recortes de diarios, entre otros.
La reconstrucción biográfica se realizó gracias al acceso a dichos documentos, la consulta
bibliográfica y el testimonio de informantes.
La descripción y fichaje del archivo de documentos, recopilados por el mismo compositor y su familia, se basa en criterios establecidos por la Norma Internacional de Archivística
ISAD (G), y permitió formalizar un fondo documental que quedará en disponibilidad para consulta. En el último capítulo se encuentran las conclusiones, donde se muestran los resultados y aportes de este trabajo, y se señalan asimismo nuevas líneas de investigación que este trabajo deja abiertas.The present bachelor's degree thesis focuses on the figure of the Argentine composer José Lo Giúdice (1900-1971), and its main aim is to revalue his role, his production and his job as a cultural manager.
The thesis has an introduction that explains the objectives, methodology and general guidelines of the work carried out, followedby two related central parts: a biography of the author, and a description and signing of the family archive, containing documents of historical relevance such as photographs, unpublished scores, writings, newspaper clippings, among others.
The biography was carried out thanks to the access to the aforementioned documents, the
bibliographical consultation and the informants’ testimony.
The description and signing of the archived documents, compiled by the same composer and his family, are based on the criteria established by the International standard of archival ISAD(G), which allows for a documental files to be built which will be available for later consultation. In the last chapter conclusions are stated, showing the results and contributions of the present research, and new lines of research are also indicated for future study.Fil: Lo Giúdice, Victoria. Universidad Nacional de Cuyo. Facultad de Artes y Diseño
Reduction of freezing of gait in Parkinson's disease by repetitive robot-assisted treadmill training: a pilot study
<p>Abstract</p> <p>Background</p> <p>Parkinson's disease is a chronic, neurodegenerative disease characterized by gait abnormalities. Freezing of gait (FOG), an episodic inability to generate effective stepping, is reported as one of the most disabling and distressing parkinsonian symptoms. While there are no specific therapies to treat FOG, some external physical cues may alleviate these types of motor disruptions. The purpose of this study was to examine the potential effect of continuous physical cueing using robot-assisted sensorimotor gait training on reducing FOG episodes and improving gait.</p> <p>Methods</p> <p>Four individuals with Parkinson's disease and FOG symptoms received ten 30-minute sessions of robot-assisted gait training (Lokomat) to facilitate repetitive, rhythmic, and alternating bilateral lower extremity movements. Outcomes included the FOG-Questionnaire, a clinician-rated video FOG score, spatiotemporal measures of gait, and the Parkinson's Disease Questionnaire-39 quality of life measure.</p> <p>Results</p> <p>All participants showed a reduction in FOG both by self-report and clinician-rated scoring upon completion of training. Improvements were also observed in gait velocity, stride length, rhythmicity, and coordination.</p> <p>Conclusions</p> <p>This pilot study suggests that robot-assisted gait training may be a feasible and effective method of reducing FOG and improving gait. Videotaped scoring of FOG has the potential advantage of providing additional data to complement FOG self-report.</p
Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers.
A phase III, multi-centre, double-masked randomised controlled trial of adjunctive intraocular and peri-ocular steroid (triamcinolone acetonide) versus standard treatment in eyes undergoing vitreoretinal surgery for open globe trauma (ASCOT): statistical analysis plan
Evaluación del grado de conocimiento interdisciplinar y del grado de interés en participar en grupos multidisciplinares de los estudiantes de Proyectos del Grado de Ingeniería Industrial e Ingeniería Química y los estudiantes de SIG avanzado del Grado en Ingeniería Geomática y Topografía
[ES] El actual contexto socio económico y laboral plantea el reto de formar a los estudiantes en competencias que les ayuden en un futuro a trabajar cooperativamente en equipos multidisciplinares. Las posibilidades de encontrar soluciones a problemas se incrementan cuando los miembros del equipo conocen el potencial que puede aportar cada uno de ellos. En este trabajo se ha evaluado la percepción del estudiantado respecto a la interdisciplinariedad y su grado de interés, con el objetivo de conocer la base sobre la cual poder aplicar innovaciones docentes que mejoren esta percepción entre los grados de Ingeniería Industrial e Ingeniería Química y el grado en Ingeniería Geomática y Topografía de la UPV. Tras diseñar y realizar una encuesta a los estudiantes, se concluye que existe una falta de conocimiento sobre las posibilidades y potencialidades de la colaboración interdisciplinar, aunque los estudiantes sí están interesados en trabajar en equipos multidisciplinares, por lo que se debería tratar de incorporar esta multidisciplinariedad en la docencia para el beneficio de los futuros egresados.[EN] The current socio-economic and labor context poses the challenge of training students in
competencies that will help them in the future to work cooperatively in multidisciplinary
teams. The possibilities of finding solutions to problems increase when the members of the
team know the potential that each of them can contribute. In this work we have evaluated
the students' perception of interdisciplinarity and their degree of interest, with the aim of
knowing the basis on which to apply teaching innovations to improve this perception
between the degrees of Industrial Engineering and Chemical Engineering and the degree in
Geomatics Engineering and Surveying of the UPV. After designing and conducting a survey
to students, it is concluded that there is a lack of knowledge about the possibilities and
potential of interdisciplinary collaboration, although students are interested in working in
multidisciplinary teams, so we should try to incorporate this multidisciplinarity in teaching
for the benefit of future graduates.Esta innovación se ha realizado gracias a los proyectos de innovación docente PIME/22-23/354 y al PIME/21-22/268.Lerma-Arce, V.; Coll Aliaga, E.; Pastor-Ferrando, JP.; Fuentes-Bargues, JL.; Lo-Iacono Ferreira, VG.; Lorenzo-Sáez, E. (2023). Evaluación del grado de conocimiento interdisciplinar y del grado de interés en participar en grupos multidisciplinares de los estudiantes de Proyectos del Grado de Ingeniería Industrial e Ingeniería Química y los estudiantes de SIG avanzado del Grado en Ingeniería Geomática y Topografía. Editorial Universitat Politècnica de València. 978-990. https://doi.org/10.4995/INRED2023.2023.1664197899
Whole brain radiotherapy (WBRT) after local treatment of brain metastases in melanoma patients: Statistical Analysis Plan
Background: The WBRTMel trial is a multinational, open-label, phase III randomised controlled trial comparing
whole brain radiotherapy (WBRT) to observation following local treatment of one to three melanoma brain metastases
with surgery and/or stereotactic irradiation. The primary trial endpoint was to determine the effect of adding WBRT to
local treatment on distant intracranial control, and the secondary endpoints were neurocognitive function,
quality of life (QoL), performance status, overall survival, death from intracranial causes, death from melanoma
and cost-effectiveness.
Objective: The objective of this update is to outline and publish the pre-determined statistical analysis plan
(SAP) before the database lock and the start of analysis.
Methods: The SAP describes basic analysis principles, methods for dealing with a range of commonly encountered
data analysis issues and the specific statistical procedures for analysing efficacy and safety outcomes. The SAP was
approved after closure of recruitment and before completion of patient follow-up. It outlines the planned primary
analyses and a range of subgroup and sensitivity analyses regarding the clinical and QoL outcomes. Health economic
outcomes are not included in this plan but will be analysed separately. The SAP will be adhered to for the final data
analysis of this trial to avoid analysis bias arising from knowledge of the data.
Results: The resulting SAP is consistent with best practice and will allow open and transparent reporting.
Conclusion: We have developed a SAP for the WBRTMel trial which will be followed to ensure high-quality standards
of internal validity to minimise analysis bias
Plasma polymer surface modified expanded polytetrafluoroethylene promotes epithelial monolayer formation in vitro and can be transplanted into the dystrophic rat subretinal space
Relationship between microstructure and fracture types in a UNS S32205 duplex stainless steel
Duplex stainless steels are susceptible to the formation of sigma phase at high temperature which could potentially be responsible for catastrophic service failure of components. Thermal treatments were applied to duplex stainless steels in order to promote the precipitation of different fractions of sigma phase into a ferrite-austenite microstructure. Quantitative image analysis was employed to characterize the microstructure and Charpy impact tests were used in order to evaluate the mechanical degradation caused by sigma phase presence. The fracture morphology of the Charpy test specimens were thoroughly observed in SEM, looking for a correlation between the microstructure and the fracture types in UNS S32205 duplex stainless steel. The main conclusion is the strong embrittlement effect of sigma phase since it is possible to observe a transition from transgranular fracture to intergranular fracture as increases the percentage of sigma phase. Thus, the mixed modes of fracture are predominant in the present study with high dependence on sigma phase percentages obtained by different thermal treatments
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