Tramp! Tramp! Tramp! (Including U.S. Marine Air Corps Version)

https://digitalcommons.library.umaine.edu/mmb-vp/6298/thumbnail.jp

M2K: I. A Jovian mass planet around the M3V star HIP79431

Doppler observations from Keck Observatory reveal the presence of a planet with Msini of 2.1 Mjup orbiting the M3V star HIP79431. This is the sixth giant planet to be detected in Doppler surveys of M dwarfs and it is one of the most massive planets discovered around an M dwarf star. The planet has an orbital period of 111.7 days and an orbital eccentricity of 0.29. The host star is metal rich, with an estimated [Fe/H] = +0.4. This is the first planet to emerge from our new survey of 1600 M-to-K dwarf stars.Comment: 5 figure

Deforming tachyon kinks and tachyon potentials

In this paper we investigate deformation of tachyon potentials and tachyon kink solutions. We consider the deformation of a DBI type action with gauge and tachyon fields living on D1-brane and D3-brane world-volume. We deform tachyon potentials to get other consistent tachyon potentials by using properly a deformation function depending on the gauge field components. Resolutions of singular tachyon kinks via deformation and applications of deformed tachyon potentials to scalar cosmology scenario are discussed.Comment: To appear in JHEP, 19 pages, 5 eps figures, minor changes and one reference adde

Bird-biting mosquitoes on farms in southern England

Mosquitoes that blood-feed on avian hosts are important vectors of many arthropod-borne viruses (arboviruses). In Europe, these include West Nile virus (WNV), Usutu virus (USUTV) and Sindbis virus. These are all maintained in enzootic bird-mosquito-bird cycles and are important veterinary and medical threats to the UK. Principally, veterinary concerns lie with the risks to domestic animals, such as the incidental spillover infection of horses with WNV which may lead to serious neurological sequelae. Wildlife may also be affected, with certain wild birds being highly susceptible to infection and death with USUTV, although poultry are less susceptible. To date, UK surveillance for these viruses has not yielded evidence of active virus transmission although serological evidence has been reported

Stellar Spin-Orbit Misalignment in a Multiplanet System

Stars hosting hot Jupiters are often observed to have high obliquities, whereas stars with multiple co-planar planets have been seen to have low obliquities. This has been interpreted as evidence that hot-Jupiter formation is linked to dynamical disruption, as opposed to planet migration through a protoplanetary disk. We used asteroseismology to measure a large obliquity for Kepler-56, a red giant star hosting two transiting co-planar planets. These observations show that spin-orbit misalignments are not confined to hot-Jupiter systems. Misalignments in a broader class of systems had been predicted as a consequence of torques from wide-orbiting companions, and indeed radial-velocity measurements revealed a third companion in a wide orbit in the Kepler-56 system.Comment: Accepted for publication in Science, published online on October 17 2013; PDF includes main article and supplementary materials (65 pages, 27 figures, 7 tables); v2: small correction to author lis

M2K: I. A Jupiter-Mass Planet Orbiting the M3V Star HIP 79431

Doppler observations from Keck Observatory reveal the presence of a planet with M sin i of 2.1 M_(Jup) orbiting the M3V star HIP 79431. This is the sixth giant planet to be detected in Doppler surveys of M dwarfs and it is one of the most massive planets discovered around an M dwarf star. The planet has an orbital period of 111.7 days and an orbital eccentricity of 0.29. The host star is metal rich, with an estimated [Fe/H] = +0.4. This is the first planet to emerge from our new survey of 1600 M-to-K dwarf stars

Mitochondrial Genetic Background Modulates Bioenergetics and Susceptibility to Acute Cardiac Volume Overload

Dysfunctional bioenergetics has emerged as a key feature in many chronic pathologies such as diabetes and cardiovascular disease. This has led to the mitochondrial paradigm in which it has been proposed that mtDNA sequence variation contributes to disease susceptibility. In the present study we show a novel animal model of mtDNA polymorphisms, the MNX (mitochondrial–nuclear exchange) mouse, in which the mtDNA from the C3H/HeN mouse has been inserted on to the C57/BL6 nuclear background and vice versa to test this concept. Our data show a major contribution of the C57/BL6 mtDNA to the susceptibility to the pathological stress of cardiac volume overload which is independent of the nuclear background. Mitochondria harbouring the C57/BL6J mtDNA generate more ROS (reactive oxygen species) and have a higher mitochondrial membrane potential relative to those with C3H/HeN mtDNA, independent of nuclear background. We propose this is the primary mechanism associated with increased bioenergetic dysfunction in response to volume overload. In summary, these studies support the ‘mitochondrial paradigm’ for the development of disease susceptibility, and show that the mtDNA modulates cellular bioenergetics, mitochondrial ROS generation and susceptibility to cardiac stress

A mitochondria-targeted mass spectrometry probe to detect glyoxals: implications for diabetes

The glycation of protein and nucleic acids that occurs as a consequence of hyperglycaemia disrupts cell function and contributes to many pathologies, including those associated with diabetes and aging. Intracellular glycation occurs following the generation of the reactive 1,2-dicarbonyls methylglyoxal and glyoxal and disruption to mitochondrial function is associated with hyperglycemia. However, the contribution of these reactive dicarbonyls to mitochondrial damage in pathology is unclear due to uncertainties about their levels within mitochondria in cells and in vivo. To address this we have developed a mitochondria-targeted reagent (MitoG) designed to assess the levels of mitochondrial dicarbonyls within cells. MitoG comprises a lipophilic triphenylphosphonium cationic function, which directs the molecules to mitochondria within cells and an o-phenylenediamine moiety that reacts with dicarbonyls to give distinctive and stable products. The extent of accumulation of these diagnostic heterocyclic products can be readily and sensitively quantified by liquid chromatography-tandem mass spectrometry (LC-MS/MS), enabling changes to be determined. Using the MitoG-based analysis we assessed the formation of methylglyoxal and glyoxal in response to hyperglycaemia in cells in culture and in the Akita mouse model of diabetes in vivo. These findings indicated that the levels of methylglyoxal and glyoxal within mitochondria increase during hyperglycaemia in both cells and in vivo, suggesting that they can contribute to the pathological mitochondrial dysfunction that occurs in diabetes and aging

The Erotic and the Vulgar: Visual Culture and Organized Labor's Critique of U.S. Hegemony in Occupied Japan

This essay engages the colonial legacy of postwar Japan by arguing that the political cartoons produced as part of the postwar Japanese labor movement’s critique of U.S. cultural hegemony illustrate how gendered discourses underpinned, and sometimes undermined, the ideologies formally represented by visual artists and the organizations that funded them. A significant component of organized labor’s propaganda rested on a corpus of visual media that depicted women as icons of Japanese national culture. Japan’s most militant labor unions were propagating anti-imperialist discourses that invoked an engendered/endangered nation that accentuated the importance of union roles for men by subordinating, then eliminating, union roles for women