31 research outputs found

    Estudios actuales de literatura comparada. TeorĂ­as de la literatura y diĂĄlogos interdisciplinarios

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    Estos dos volĂșmenes constituyen una contribuciĂłn al desarrollo de la comparatĂ­stica que se realiza, principalmente, desde AmĂ©rica Latina. El primer volumen estĂĄ organizado en tres partes y consta de 22 artĂ­culos, mientras que el segundo reĂșne 24 capĂ­tulos.UCR::VicerrectorĂ­a de Docencia::Artes y Letras::Facultad de Letras::Escuela de FilologĂ­a, LingĂŒĂ­stica y LiteraturaUCR::VicerrectorĂ­a de Docencia::Ciencias BĂĄsicas::Sistema de EducaciĂłn General::Escuela de Estudios GeneralesUCR::VicerrectorĂ­a de InvestigaciĂłn::Sistema de Estudios de Posgrado::Artes y Letras::MaestrĂ­a AcadĂ©mica en Literatura FrancesaUCR::VicerrectorĂ­a de InvestigaciĂłn::Sistema de Estudios de Posgrado::Artes y Letras::MaestrĂ­a AcadĂ©mica en Literatura LatinoamericanaUCR::VicerrectorĂ­a de Docencia::Artes y Letras::Facultad de Letras::Escuela de Lenguas Moderna

    Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

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    The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

    Measurement of the low-energy antideuteron inelastic cross section

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    In this Letter, we report the first measurement of the inelastic cross section for antideuteron-nucleus interactions at low particle momenta, covering a range of 0.3 ≀ p < 4 GeV/c. The measurement is carried out using p-Pb collisions at a center-of-mass energy per nucleon–nucleon pair of sNN\sqrt{s_{\rm NN}} = 5.02 TeV, recorded with the ALICE detector at the CERN LHC and utilizing the detector material as an absorber for antideuterons and antiprotons. The extracted raw primary antiparticle-to-particle ratios are compared to the results from detailed ALICE simulations based on the geant4 toolkit for the propagation of (anti)particles through the detector material. The analysis of the raw primary (anti)proton spectra serves as a benchmark for this study, since their hadronic interaction cross sections are well constrained experimentally. The first measurement of the inelastic cross section for antideuteron-nucleus interactions averaged over the ALICE detector material with atomic mass numbers ⟹A⟩ = 17.4 and 31.8 is obtained. The measured inelastic cross section points to a possible excess with respect to the Glauber model parametrization used in geant4 in the lowest momentum interval of 0.3 ≀ p < 0.47 GeV/c up to a factor 2.1. This result is relevant for the understanding of antimatter propagation and the contributions to antinuclei production from cosmic ray interactions within the interstellar medium. In addition, the momentum range covered by this measurement is of particular importance to evaluate signal predictions for indirect dark-matter searches

    Pseudorapidity distributions of charged particles as a function of mid- and forward rapidity multiplicities in pp collisions at s\sqrt{s} = 5.02, 7 and 13 TeV

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    The multiplicity dependence of the pseudorapidity density of charged particles in proton–proton (pp) collisions at centre-of-mass energies s = 5.02\sqrt{s}~=~5.02, 7 and 13 TeV measured by ALICE is reported. The analysis relies on track segments measured in the midrapidity range (∣η∣<1.5|\eta | < 1.5). Results are presented for inelastic events having at least one charged particle produced in the pseudorapidity interval ∣η∣<1|\eta |<1. The multiplicity dependence of the pseudorapidity density of charged particles is measured with mid- and forward rapidity multiplicity estimators, the latter being less affected by autocorrelations. A detailed comparison with predictions from the PYTHIA 8 and EPOS LHC event generators is also presented. The results can be used to constrain models for particle production as a function of multiplicity in pp collisions

    Elliptic Flow of Electrons from Beauty-Hadron Decays in Pb-Pb Collisions at sNN\sqrt {s_{NN}} = 5.02 TeV

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    The elliptic flow of electrons from beauty hadron decays at midrapidity (|y|<0.8) is measured in Pb-Pb collisions at sNN\sqrt {s_{NN}} = 5.02 TeV with the ALICE detector at the LHC. The azimuthal distribution of the particles produced in the collisions can be parametrized with a Fourier expansion, in which the second harmonic coefficient represents the elliptic flow, v2v_2. The v2v_2 coefficient of electrons from beauty hadron decays is measured for the first time in the transverse momentum (pTp_T) range 1.3–6 GeV/c in the centrality class 30%–50%. The measurement of electrons from beauty-hadron decays exploits their larger mean proper decay length cτ ≈ 500 ÎŒm compared to that of charm hadrons and most of the other background sources. The v2v_2 of electrons from beauty hadron decays at midrapidity is found to be positive with a significance of 3.75 σ. The results provide insights into the degree of thermalization of beauty quarks in the medium. A model assuming full thermalization of beauty quarks is strongly disfavored by the measurement at high pTp_T, but is in agreement with the results at low pTp_T. Transport models including substantial interactions of beauty quarks with an expanding strongly interacting medium describe the measurement within uncertainties

    J/ψ\psi production as a function of charged-particle multiplicity in p-Pb collisions at sNN = 8.16\sqrt{\textit{s}_{\rm NN}}~=~8.16 TeV

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    Inclusive J/ψ yields and average transverse momenta in p-Pb collisions at a center-of-mass energy per nucleon pair sNN \sqrt{s_{\mathrm{NN}}} = 8.16 TeV are measured as a function of the charged-particle pseudorapidity density with ALICE. The J/ψ mesons are reconstructed at forward (2.03 < ycms_{cms}< 3.53) and backward (−4.46 < ycms_{cms}< −2.96) center-of-mass rapidity in their dimuon decay channel while the charged-particle pseudorapidity density is measured around midrapidity. The J/ψ yields at forward and backward rapidity normalized to their respective average values increase with the normalized charged-particle pseudorapidity density, the former showing a weaker increase than the latter. The normalized average transverse momenta at forward and backward rapidity manifest a steady increase from low to high charged-particle pseudorapidity density with a saturation beyond the average value

    Publisher Correction: Unveiling the strong interaction among hadrons at the LHC

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    Correction to: Nature https://doi.org/10.1038/s41586-020-3001-6Published online 09 December 2020 In Fig. 1c of this Article, owing to an error during the production process, the equation incorrectly began ‘C(k*, r*) = 
’ instead of ‘C(k*) = 
’. In addition, in affiliation 71 ‘Dipartimento di Fisica dell’Università degli studi di Bari Aldo Moro’ has been corrected to read ‘Dipartimento di Fisica dell’Università degli studi di Cagliari’. The original Article has been corrected online

    Measurement of isolated photon–hadron correlations in √sNN = 5.02 TeV pp and p–Pb collisions

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    This paper presents isolated photon-hadron correlations using pp and p-Pb data collected by the ALICE detector at the LHC. For photons with |η| < 0.67 and 12 < pT < 40 GeV/c, the associated yield of charged particles in the range |η| < 0.80 and 0.5 < pT < 10 GeV/c is presented. These momenta are much lower than previous measurements at the LHC. No significant difference between pp and p-Pb is observed, with PYTHIA 8.2 describing both data sets within uncertainties. This measurement constrains nuclear effects on the parton fragmentation in p-Pb collisions, and provides a benchmark for future studies of Pb-Pb collisions

    J/ψ production as a function of charged-particle multiplicity in p–Pb collisions at √sNN = 8.16 TeV

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    Inclusive J/ψ yields and average transverse momenta in p-Pb collisions at a center-of-mass energy per nucleon pair sNN−−−√ = 8.16 TeV are measured as a function of the charged-particle pseudorapidity density with ALICE. The J/ψ mesons are reconstructed at forward (2.03<ycms<3.53) and backward (−4.46<ycms<−2.96) center-of-mass rapidity in their dimuon decay channel while the charged-particle pseudorapidity density is measured around midrapidity. The J/ψ yields at forward and backward rapidity normalized to their respective average values increase with the normalized charged-particle pseudorapidity density, the former showing a weaker increase than the latter. The normalized average transverse momenta at forward and backward rapidity manifest a steady increase from low to high charged-particle pseudorapidity density with a saturation beyond the average value

    J/ψ elliptic and triangular flow in Pb–Pb collisions at √sNN = 5.02 TeV

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    The inclusive J/ψ elliptic (v2) and triangular (v3) flow coefficients measured at forward rapidity (2.5 <y< 4) and the v2 measured at midrapidity (|y|< 0.9) in Pb-Pb collisions at sNN−−−√ = 5.02 TeV using the ALICE detector at the LHC are reported. The entire Pb-Pb data sample collected during Run 2 is employed, amounting to an integrated luminosity of 750 ÎŒb−1 at forward rapidity and 93 ÎŒb−1 at midrapidity. The results are obtained using the scalar product method and are reported as a function of transverse momentum pT and collision centrality. At midrapidity, the J/ψ v2 is in agreement with the forward rapidity measurement. The centrality averaged results indicate a positive J/ψ v3 with a significance of more than 5σ at forward rapidity in the pT range 2<pT<5 GeV/c. The forward rapidity v2, v3, and v3/v2 results at low and intermediate pT (pTâ‰Č8 GeV/c) exhibit a mass hierarchy when compared to pions and D mesons, while converging into a species-independent curve at higher pT. At low and intermediate pT, the results could be interpreted in terms of a later thermalization of charm quarks compared to light quarks, while at high pT, path-length dependent effects seem to dominate. The J/ψ v2 measurements are further compared to a microscopic transport model calculation. Using a simplified extension of the quark scaling approach involving both light and charm quark flow components, it is shown that the D-meson vn measurements can be described based on those for charged pions and J/ψ flow
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