Novel Alkyne And Phosphaalkyne Coupling On An Ir4 Cluster: Synthesis And Molecular Structure Of [ir4(μ-co)(co) 7{μ4-η3-ph2 Pc(h)c(ph)pcbut}(μ-pph2)]

The cluster compound [(μ-H)Ir4(CO)9(Ph 2PCCPh)(μ-PPh2)] 1 reacts with the phosphaalkyne ButCP to yield [Ir4(μ-CO)(CO) 7{μ4-η3-Ph2 PC(H)C(Ph)PCBut}(μ-PPh2)] 3, containing the novel 2-phosphabutadienylphosphine fragment as a result of the coupling of Bu tCP with the diphenylphosphinoalkyne ligand and incorporation of the cluster bound H atom.161869187

Assessment of Functional Activities in Individuals with Parkinson's Disease Using a Simple and Reliable Smartphone-Based Procedure

[EN] Parkinson's disease (PD) is a progressive neurodegenerative disorder leading to functional impairment. In order to monitor the progression of the disease and to implement individualized therapeutic approaches, functional assessments are paramount. The aim of this study was to determine the impact of PD on balance, gait, turn-to-sit and sit-to-stand by means of a single short-duration reliable test using a single inertial measurement unit embedded in a smartphone device. Study participants included 29 individuals with mild-to moderate PD (PG) and 31 age-matched healthy counterparts (CG). Functional assessment with FallSkip((R)) included postural control (i.e., Medial-Lateral (ML) and Anterior-Posterior (AP) displacements), gait (Vertical (V) and Medial-Lateral (ML) ranges), turn-to-sit (time) and sit-to-stand (power) tests, total time and gait reaction time. Our results disclosed a reliable procedure (intra-class correlation coefficient (ICC) = 0.58-0.92). PG displayed significantly larger ML and AP displacements during the postural test, a decrease in ML range while walking and a longer time needed to perform the turn-to-sit task than CG (p 0.05). In conclusion, people with mild-to-moderate PD exhibit impaired postural control, altered gait strategy and slower turn-to-sit performance than age-matched healthy people.This project (IMAMCJ/2020/1) was funded by Instituto Valenciano de Competitividad Empresarial (IVACE) and by the Valencian Regional Government (IVACE-GVA).Serra-Añó, P.; Pedrero, J.; Inglés, M.; Aguilar-Rodríguez, M.; Vargas-Villanueva, I.; Lopez Pascual, J. (2020). Assessment of Functional Activities in Individuals with Parkinson's Disease Using a Simple and Reliable Smartphone-Based Procedure. International Journal of Environmental research and Public Health (Online). 17(11):1-13. https://doi.org/10.3390/ijerph17114123S1131711Soh, S.-E., McGinley, J. L., Watts, J. J., Iansek, R., Murphy, A. T., Menz, H. B., … Morris, M. E. 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Neuroscience, 119(1), 293-308. doi:10.1016/s0306-4522(03)00095-2Błaszczyk, J. W., Orawiec, R., Duda-Kłodowska, D., & Opala, G. (2007). Assessment of postural instability in patients with Parkinson’s disease. Experimental Brain Research, 183(1), 107-114. doi:10.1007/s00221-007-1024-yCavagna, G. A., & Margaria, R. (1966). Mechanics of walking. Journal of Applied Physiology, 21(1), 271-278. doi:10.1152/jappl.1966.21.1.271Nguyen, H., Lebel, K., Boissy, P., Bogard, S., Goubault, E., & Duval, C. (2017). Auto detection and segmentation of daily living activities during a Timed Up and Go task in people with Parkinson’s disease using multiple inertial sensors. Journal of NeuroEngineering and Rehabilitation, 14(1). doi:10.1186/s12984-017-0241-2Hahn, M. E., & Chou, L.-S. (2003). Can motion of individual body segments identify dynamic instability in the elderly? Clinical Biomechanics, 18(8), 737-744. doi:10.1016/s0268-0033(03)00139-6Donelan, J. M., Shipman, D. W., Kram, R., & Kuo, A. D. (2004). 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Tratamiento quirúrgico con placa bloqueada en fracturas de fémur distal tipo C en pacientes mayores de 60 años

Objetivo. Determinar el resultado clínico, radiológico y complicaciones asociadas del tratamiento con placa bloqueada en fracturas distales de fémur tipo C en pacientes mayores de 60 años. Material y métodos. Estudio descriptivo retrospectivo de 16 pacientes. Se registraron variables epidemiológicas, comorbilidades, complicaciones y resultados clínicos y radiológicos. Resultados. Edad media de 75,3 años. El seguimiento medio fue de 13,5 meses. La flexión media postoperatoria de la rodilla fue de 61,6º. Sólo un 12,5% de los pacientes no referían gonalgia ni precisaban ayudas para la deambulación al final del seguimiento. Radiológicamente, en un 68,7% la translación femoral era mayor de 5 mm, y en un 31,3% la reducción en el plano lateral no era correcta. Se consiguió la consolidación de la fractura en 13 pacientes (86,6%), con un tiempo medio de 10,2 semanas. Como complicaciones hubo una pseudoartrosis, una consolidación viciosa y una infección. Discusión. El tratamiento de la fractura distal de fémur con placa bloqueada viene avalado en la literatura como un método fiable. Sin embargo, en nuestra serie, hemos tenido un alto porcentaje de malos resultados clínicos con presencia de dolor en la rodilla y necesidad de ayudas para la deambulación.Objective. To evaluate functional and radiographic results, and complications, after surgical treatment with locked plate in fractures of the distal femur in patients 60 years old or older. Material and methods. We reviewed 16 patients. We recorded epidemiological variables, comorbidities, functional and radiographic results. Results. Mean aged of 75,3 years. Mean follow-up of 13,5 months. Mean knee flexion of 61,6º. Only 12,5% of the patients did not refer knee pain and walked unaided. Radiologically, in 68,7% of the patients femoral translation was greater than 5 mm, and in 31,3% lateral reduction was not correct. Fracture healed in 13 patients (86,6%), in a mean time of 10,2 weeks. There were 1 nonunion, 1 malunion, and 1 infection. Discussion. Locked plating is a realiable treatment for distal femoral fractures. But, in our elderly serie, we experienced bad clinical results with high percentage of knee pain and walking aid

Contribución al estudio polínico de la flora de la cuenca Laguna Avendaño (Ñuble, Chile)

García María E., Nora J. F. Reyes, Patricia N. Vargas. 2016. “Contribu- ción al estudio polínico de la flora de la cuenca Laguna Avendaño (Ñuble-Chile)”. Lilloa 53 (1). Se analiza la morfología polínica de 29 especies nativas, típicas de la zona mediterránea de Chile. El objetivo de la investigación es aportar nuevos datos sobre la flora polínica de la zona central y de esta forma contribuir a la información disponible para estudios paleopalinológi- cos. Se trabajó con material recolectado dentro de la cuenca de la Laguna Avendaño y con algunos ejemplares provenientes del Herbario de la Universidad de Concepción. Las muestras fueron acetolizadas. Se analizaron y se tomaron fotos con microscopía óptica (MO). Las caracterizaciones polínicas amplían estudios previos realizados por diversos autores excepto en 2 de las especies consideradas, que son descriptas por primera vez, Baccharis pingraea DC. y Haplopappus integerrimus (Hook. & Arn.) H.M. Hall , (Asteraceae)

Adrenalectomía laparoscópica por metástasis metácrona. Experiencia en 12 casos

To assess the peroperative and oncological results of laparoscopic adrenalectomy for an isolated metastasis. MATERIAL AND METHODS: A retrospective, descriptive study was conducted of 12 laparoscopic adrenalectomies performed for metastases out of a total of 40 adrenalectomies performed from May 1998 to April 2009. The primary tumor was pulmonary in 7 patients, renal in 3, and colonic in 2. Demographic data collected included median age, operating time, blood loss, complications, tumor size, and length of hospital stay. The Kaplan-Meier method was used to analyze survival. RESULTS: Operating time was 150 min (range, 90-206). Peroperative bleeding was 60 ml (range, 15-150). Peroperative complications occurred in 3% of patients. Tumor size was 4.5 cm (range, 1.3-8.5). No positive margins were seen in the resected specimens. Hospital stay was 3 days (range 3-5). Actuarial survival was 55.6% at 23 months (range, 2-38) with mean and median follow-up times of 20.9 and 23 months. CONCLUSIONS: In selected patients, laparoscopic adrenalectomy for metastasis is a safe procedure with oncological results superimposable to those of open surgery

Nefrectomía parcial laparoscópica. Análisis de los primeros 30 casos de nuestra serie y revisión de la literatura

Objective: Our goal is to analyze the surgical and clinicopathological results of our first 30 laparoscopic partial nephrectomies (LPN) performed consecutively and correlate the results with the literature. Material and methods: This is a cases series, with 30 patients (20 men and 10 women) operated between 2006 and 2008. We assessed the clinicopathological factors and complications. The mean and median follow-up was 25 and 5 months. Results: Resected tumors had an average size of 2.4 cm. 60% of the tumors were malignant. The pathological stage was pT1 in 100% of cases (47% grade I, 53% Fuhrman grade II). Surgical margins were positive in 3 cases, switching to open surgery. Intraoperative bleeding was 74.66 cc (35.7±SD) and 70 cc of mean and median. The mean operative time was 214.4min (±69) and ischemia time of 31.3min (±13.8). Conclusions: Our results are similar to those reported in the literature, except for positive margins and conversion attributable to the learning curve

Association of crossed renal ectopia and aortic aneurism. Case report

OBJECTIVE: Renal malformations are rare entities and rarely have clinical consequences. Crossed renal ectopia has an incidence of 1/2.000 autopsies. The association with aortic aneurysm is even more exceptional. METHODS: We present our case and perform a bibliographic review. RESULTS: To date and in our knowledge , seven cases of crossed renal ectopia associated with aortic aneurysm were described on the literature. This malformation makes the treatment of the aneurysm more complex. The possibility of renal function decrease caused by injuries to the renal arteries during the surgical procedure is always present. Because of this risk of injury of the kidney during surgery preoperative evaluation of the vascularization must include image technologies as the MRI, CT-angiography or conventional arteriography. During the aortic intervention vascular conservation must be performed and it is necessary to minimize the time of renal ischemia. CONCLUSIONS: The association of crossed renal ectopia and aortic aneurysm is a rare event. The surgical intervention of the aorta does not have to necessarily originate a loss of renal function. Anyway the worsening of the renal clearance must be foreseen