338 research outputs found
Numerical study of imperfect liquid-filled conical shells - Verifying the present design rule
TRANSITION ACTIVITIES AND THEIR EFFECTS ON MIDDLE SCHOOL STUDENTS
The purpose of this study was to determine the effectiveness that transitional activities have on student achievement and attendance when students moved from elementary school to middle school. The data were gathered from two school districts that are demographically similar. Data included average daily attendance rates, Terra Nova Achievement Scores from social studies in grades five, six, and seven, as well as math in grades five, six, and seven. There were 187 students in the Treatment Group and 147 in the Control Group for a total of 334 students. Comparison of means for demographic equivalency of the groups (t-test) and a MANCOVA with repeated measures analysis of seventh grade Math and Social Studies test scores were run. The results indicated no significant differences in rates of attendance from students transitioning from elementary to middle school whether they have experienced transitional activities or not. In addition, there were no significant differences in Terra Nova Social Studies or Math Achievement Test scores between students transitioning from elementary to middle school whether they have experienced a comprehensive transition program or not (F= .003, p= .960 for seventh grade Math, F= .947, p= .331 for seventh grade Social Studies). There was a drop in both attendance and achievement test scores for both the control and treatment groups. While this study determined there is no reason to believe the interventions made any difference in the overall attendance and achievement test scores, the literature and other studies have shown positive results. Programs of this sort need further study and analysis to gather additional data on transitional activities and their effectiveness on students entering middle school
Comparison of Numerically Determined Failure Loads of Liquid-Filled Conical Shells with Experimental Test Results
Vulnerable responsibility
The authors have developed the ethical imagination inviting a sense of “otherness” towards the vulnerable self, rebounding care for the other as a way to understand our everyday neurotic (normal) tendency of small vices as the propensity and possibility for responsibility towards the other. The authors, inviting the reader into troublesome feelings such as laziness and anger, bring a Levinasian horizon into focus, so that even in the midst of laziness, there remains the small goodness to set the self free to care for the other, meeting the demands, challenges, hesitation, shuddering, tension and shocks of such alterity, of living “otherwise”
Die bydrae van ’n haalbare gasvryheids- en ontmoetingsetiek in die etiese versorging van gesondheidsorgwerkers
Published ArticleThe authors of this study advocate for the contribution a double ethic of hospitality
and engagement can make towards the ethical care of healthcare workers. Their
contribution is based on two studies in healthcare. The South African case outlines
challenges with regard to resources, communication and expectations. The Belgium
case study draws attention to the traditional approach and suggests a new paradigm,
namely to respect the patient as subject and therefore the importance of meeting the
patient in his/her situation. Both cases sensitise the reader to the ethical vulnerability
of the healthcare worker suggesting that a double ethic of hospitality and engagement
is needed to address this challenge. The question of ethical coaching is addressed via a
real life example in which the healthcare workers are placed in a simulation laboratory
and then treated as “patients” by other healthcare workers. This simulation gives insight
into the real needs of patients and how healthcare workers should care for them
IL-17 produced by Paneth cells drives TNF-induced shock
Tumor necrosis factor (TNF) has very potent antitumor activity, but it also provokes a systemic inflammatory response syndrome that leads to shock, organ failure, and death. Here, we demonstrate that interleukin (IL)-17, a proinflammatory cytokine known to be produced mainly by activated T cells, has a critical role in this process. Antiserum against IL-17 or deletion of Il17r protected mice against a lethal TNF challenge. Serum levels of TNF-induced IL-6 and nitric oxide metabolites were significantly reduced in mice deficient in the IL-17R. TNF-induced leukocyte influx in the small intestine was reduced, and there was no injury to the small intestine. Surprisingly, electron microscopy showed that IL-17 was constitutively present in Paneth cells of the crypts. Upon TNF challenge, the intracellular pool of IL-17 in these cells was drastically reduced, suggesting rapid release of IL-17 from the granules of Paneth cells. Our findings assign a novel role for IL-17 in an acute inflammation and identify Paneth cells as a source of the IL-17 that plays a role in this process. These data indicate that innate immune cytokine responses in the local mucosa may participate in rapidly amplifying responses to systemic inflammatory challenges
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