The largest hyper-rectangle in a three dimensional orthogonal polyhedron

Given a three dimensional orthogonal polyhedron P, we present a simple and efficient algorithm for finding the three dimensional orthogonal hyper-rectangle R of maximum volume, such that R is completely contained in P. Our algorithm finds out the three dimensional hyper-rectangle of maximum volume by using space sweep technique and enumerating all possible such rectangles. The presented algorithm runs in O(($n^2$+K)logn) time using O(n) space, where n is the number of vertices of the given polyhedron P and K is the number of reported three dimensional orthogonal hyper-rectangles for a problem instance, which is O($n^3$) in the worst case

Scrutinizing the Structural Response of Regular and Irregular Structure (With and Without Shear Wall) Subjected to Seismic and Wind Loading

The spectacular increase in population, living in urban areas and their demands leads to housing problem in India. This results in the rise of multi-storey and high-rise building with irregular configuration. Past earthquake occurrences in India reveals that the buildings with irregular configuration are prone to earthquake damage. Therefore, it is obligatory to identify the seismic and wind response of structures with irregular shape in different zones of India. Shear Wall system is one of the most common systems used for lateral load resistance. It is necessary to identify the response of structure in different zones of India with and without Shear Wall. In the present study the main focus is to thoroughly examine and have a comparative study of the behavior of regular and irregular R.C building with and without shear wall for seismic and wind load activities in different zones of India. Analysis has been done in CYPE Software

Roleplay: A Tool for Engaging English Language Learners

This article examines the advantages of incorporating roleplay into academic environments, with a specific emphasis on its ability to improve communication and promote the acquisition of vocabulary among students. The study explores the design concerns and assessment methodologies used in roleplay exercises in academic settings, emphasising their efficacy in fostering critical thinking, argumentation skills, and a profound comprehension of course material. The study investigates the impact of roleplay activities on learners\u27 readiness for real-life business interactions, acquisition of negotiation skills, and improvement of professional communication in business environments

Studies on the production of some important secondary metabolites from the medicinal plants by plant tissue cultures.

[[abstract]]Plants are a tremendous source for the discovery of new products of medicinal value for drug development. Today several distinct chemicals derived from plants are important drugs currently used in one or more countries in the world. Many of the drugs sold today are simple synthetic modifications or copies of the naturally obtained substances. The evolving commercial importance of secondary metabolites has in recent years resulted in a great interest in secondary metabolism, particularly in the possibility of altering the production of bioactive plant metabolites by means of tissue culture technology. Plant cell culture technologies were introduced at the end of the 1960’s as a possible tool for both studying and producing plant secondary metabolites. Different strategies, using an in vitro system, have been extensively studied to improve the production of plant chemicals. The focus of the present review is the application of tissue culture technology for the production of some important plant pharmaceuticals. Also, we describe the results of in vitro cultures and production of some important secondary metabolites obtained in our laboratory

The MILLET MISSION: The potential to combat non-communicable diseases and future research opportunities in India

NCD Burden and the role of nutritionChronic diseases, often known as non-communicable diseases (NCDs), pose a significant threat to worldwide public health. As per World Health Organisation (WHO), NCDs account for 74% of all fatalities worldwide, with cardiovascular disease, cancer, respiratory disease, and diabetes being the leading causes.[1] Inadequate nutrition, including diets heavy in sugar, salt, saturated and trans fats, and deficient in fruits, vegetables, whole grains, and lean protein sources, is a significant risk factor for NCDs. The World Health Organization suggests a diet rich in fruits, vegetables, whole grains, nuts, and seeds and low in processed foods, sugar, saturated and trans fats.[2

Health-Beneficial Phenolic Aldehyde in Antigonon leptopus Tea

Tea prepared from the aerial parts of Antigonon leptopus is used as a remedy for cold and pain relief in many countries. In this study, A. leptopus tea, prepared from the dried aerial parts, was evaluated for lipid peroxidation (LPO) and cyclooxygenase (COX-1 and COX-2) enzyme inhibitory activities. The tea as a dried extract inhibited LPO, COX-1 and COX-2 enzymes by 78%, 38% and 89%, respectively, at 100 μg/mL. Bioassay-guided fractionation of the extract yielded a selective COX-2 enzyme inhibitory phenolic aldehyde, 2,3,4-trihydroxy benzaldehyde. Also, it showed LPO inhibitory activity by 68.3% at 6.25 μg/mL. Therefore, we have studied other hydroxy benzaldehydes and their methoxy analogs for LPO, COX-1 and COX-2 enzymes inhibitory activities and found that compound 1 gave the highest COX-2 enzyme inhibitory activity as indicated by a 50% inhibitory concentration (IC50) at 9.7 μg/mL. The analogs showed only marginal LPO activity at 6.25 μg/mL. The hydroxy analogs 6, 7 and 9 showed 55%, 61% and 43% of COX-2 inhibition at 100 μg/mL. However, hydroxy benzaldehydes 3 and 12 showed selective COX-1 inhibition while compounds 4 and 10 gave little or no COX-2 enzyme inhibition at 100 μg/mL. At the same concentration, compounds 14, 21 and 22 inhibited COX-1 by 83, 85 and 70%, respectively. Similarly, compounds 18, 19 and 23 inhibited COX-2 by 68%, 72% and 70%, at 100 μg/mL. This is the first report on the isolation of compound 1 from A. leptopus tea with selective COX-2 enzyme and LPO inhibitory activities

A Privacy Protection Mechanism for Mobile Online Social Networks

A Location sharing system is the most critical component in mobile online social networks (MOSNS).Huge number of user\u27s location information will be stored by the service providers. In addition to the location privacy and social network privacy cannot be guaranteed to the user in the earlier work. Regarding the enhanced privacy against the inside attacker implemented by the service provider in (MOSNS), we initiate a new architecture with multiple servers .It introduces a protected solution which supports a location sharing among friends and strangers. The user friend set in each query is submitted to the location server it divides into multiple subset by the location server. If the user makes a query to the server the data can be retrieved only for the registered users instead of all. We use Three Layer of Security likely, High, Medium and Low for the Privacy implementation. Simultaneously with a location sharing it offers check ability of the searching results reoccurred from the servers. We also prove that the new construction is safe under the stronger security model with enhanced privacy

Study of simple sequence repeat (SSR) polymorphism for biotic stress resistance in elite rice variety JGL 1798

To provide ready to use markers for back ground selection in marker assisted breeding of rice, we used GPP 2 as donor parent for xa13, Xa21, Gm4 resistance to bacterial blight, gall midge and NLR 145 as another donor parent for Pi-kh gene resistance to blast and JGL 1798 as recurrent parent was investigated using 128 simple sequence repeat (SSR) primers covered on chromosome number 1-12. The results reveal that 36 HRM primers showed distinct polymorphism among the donor and recurrent parents studied indicating the robust nature of microsatellites in revealing polymorphism. Based on this study, the large range of similarity values for related cultivars using microsatellites provides greater confidence for the assessment of simple sequence repeats (SSR) polymorphism.Keywords: Simple sequence repeats (SSR), parental polymorphism, JGL 1798, hyper variable markersAfrican Journal of Biotechnology Vol. 12(40), pp. 5833-583