Reading about minds: The social-cognitive potential of narratives

It is often argued that narratives improve social cognition, either by appealing to social-cognitive abilities as we engage with the story world and its characters, or by conveying social knowledge. Empirical studies have found support for both a correlational and a causal link between exposure to (literary, fictional) narratives and social cognition. However, a series of failed replications has cast doubt on the robustness of these claims. Here, we review the existing empirical literature and identify open questions and challenges. An important conclusion of the review is that previous research has given too little consideration to the diversity of narratives, readers, and social-cognitive processes involved in the social-cognitive potential of narratives. We therefore establish a research agenda, proposing that future research should focus on (1) the specific text characteristics that drive the social-cognitive potential of narratives, (2) the individual differences between readers with respect to their sensitivity to this potential, and (3) the various aspects of social cognition that are potentially affected by reading narratives. Our recommendations can guide the design of future studies that will help us understand how, for whom, and in what respect exposure to narratives can advantage social cognition

Кодикография и Компьютер

This paper was presented at the "International Data Bases for Medieval Manuscript Studies" conference at Katholieke Universiteit, Nijmegen, September 1987.Albert Gruijs, professor of Ancillary Historical Disciplines, Katholieke Universiteit (Catholic University), Nijmegen; William R. Veder, professor of Slavic Philology, Katholieke Universiteit (Catholic University), NijmegenA. Gruijs and J. van Krieken - Katholieke Universiteit (Catholic University), NijmegenOn 1 August 1980, a research team was formed at the Catholic University (Nijmegen) to create a system for description and cataloguing of manuscripts, the PCC (= Producing Codicological Catalogues with the Aid of Computers) project under the direction of professors Albert Gruijs (Ancillary Historical Disciplines) and Cees Koster (Informatics); at the end of 1981, they were joined by professor William Veder (Slavic Philology). They reviewed all extant methods of manuscript description and cataloguing including all experiences in electronic recording and processing of the relevant data, and decided to create a comprehensive system that would satisfy certain requirements.... At the end of 1983, a Dutch version of the SDDR recording software was produced for use on Philips P 2000 and the portable Osborne M 1 PC's under the CP/M operating system; also, a Dutch user's manual for this part of the system was produced. At the same time, an extensive description of the codicological side of the system was published, the book "Codicografie en computer" (= Nijmeegse codicologische cahiers 1) Nijmegen (AI fa) 1983, the essentials of which are rendered here in parallel English and Russian text, the examples from Latin and Low German manuscripts being replaced simultaneously by examples from Slavic manuscripts.A brief summary of the project is given, followed by a long list of descriptive elements desirable for encoding manuscript descriptions. The article provides parallel text in both English and Russian

Tissue levels of matrix metalloproteinases MMP-2 and MMP-9 are related to the overall survival of patients with gastric carcinoma.

Proteinases are involved in tumour invasion and metastasis. Several matrix metalloproteinases (MMPs) have been shown to be increased in various human carcinomas. We assessed the levels of MMP-2 (gelatinase A) and MMP-9 (gelatinase B) in 50 gastric carcinomas and corresponding mucosa using quantitative gelatin zymography. Both MMP levels were significantly enhanced in gastric carcinomas compared with adjacent mucosal tissue, showed a relatively poor intercorrelation and no relation was found with histopathological carcinoma classifications according to Laurén, WHO and tumour-node-metastasis (TNM). Cox's multivariate proportional hazards analyses revealed that high carcinomatous MMP values are of prognostic significance for a poor overall survival of the patients, independent of the major clinicopathological parameters

Uniform Noting for International Application of the Tumor-Stroma Ratio as an Easy Diagnostic Tool: Protocol for a Multicenter Prospective Cohort Study

Surgical oncolog

The Role of Dectin-2 for Host Defense Against Disseminated Candidiasis

Acknowledgments This work was supported by European Union ALLFUN (FP7/2007 2013, HEALTH-2010-260338) (Fungi in the setting of inflammation, allergy and autoimmune diseases: Translating basic science into clinical practices ‘‘ALLFUN’’) to D.C.I., F.C., C.F., M.G.N., and N.A.R.G. M.G.N and J.Q. were supported by a Vici grant of The Netherlands Organization of Scientific Research (to M.G.N.). M.G.N. was supported by an ERC Consolidator Grant (nr. 310372). N.A.R.G. was also supported by the Wellcome Trust (086827, 075470, 097377, & 101873).Peer reviewedPublisher PD

Risk of urothelial bladder cancer in Lynch syndrome is increased, in particular among MSH2 mutation carriers

Contains fulltext : 89346.pdf (publisher's version ) (Open Access)BACKGROUND: Colorectal, endometrial and upper urinary tract tumours are characteristic for Lynch syndrome (hereditary non-polyposis colon carcinoma, HNPCC). The aim of the present study was to establish whether carriers of mutations in mismatch repair genes MLH1, MSH2 or MSH6 are at increased risk of urinary bladder cancer. METHODS: Carriers and first degree relatives of 95 families with a germline mutation in the MLH1 (n=26), MSH2 (n=43), or MSH6 (n=26) gene were systematically questioned about the occurrence of carcinoma. The cumulative risk of cancer occurring before the age of 70 years (CR70) was compared to the CR70 of the general Dutch population. Microsatellite instability (MSI) testing and/or immunohistochemistry (IHC) for mismatch repair proteins was performed on bladder tumour tissue. RESULTS: Bladder cancer was diagnosed in 21 patients (90% men) from 19 Lynch syndrome families (2 MLH1, 15 MSH2, and 4 MSH6). CR70 for bladder cancer was 7.5% (95% CI 3.1% to 11.9%) for men and 1.0% (95% CI 0% to 2.4%) for women, resulting in relative risks for mutation carriers and first degree relatives of 4.2 (95% CI 2.2 to 7.2) for men and 2.2 (95% CI 0.3 to 8.0) for women. Men carrying an MSH2 mutation and their first degree relatives were at highest risks: CR70 for bladder and upper urinary tract cancer being 12.3% (95% CI 4.3% to 20.3%) and 5.9% (95% CI 0.7% to 11.1%). Bladder cancer tissue was MSI positive in 6/7 tumours and loss of IHC staining was found in 14/17 tumours, indicating Lynch syndrome aetiology. CONCLUSION: Patients with Lynch syndrome carrying an MSH2 mutation are at increased risk of urinary tract cancer including bladder cancer. In these cases surveillance should be considered.01 juli 201

'Othering' and Physical Education in Norway

Røset L, Green K, Thurston M. (2020). ‘Even if you don’t care…you do care after all’: ‘Othering’ and physical education in Norway. European Physical Education Review, 26(3), 622-641. Copyright © [2020] (Copyright Holder). Reprinted by permission of SAGE Publications.In the past decade or more, improving young people’s mental health has been identified as a priority for policy-makers in many countries, including Norway. Physical education (PE), as a setting for physical activity, is increasingly viewed as having a potentially significant role to play in addressing mental health among the young. This paper reports the findings from a study of 148 Norwegian youngsters (68 girls and 80 boys) from the 10th grade (15-16 year olds) in eight secondary schools in Norway in 2017. It explores Norwegian youngsters’ experiences of PE in relation to aspects of their mental health – specifically, being judged and, by extension, ‘othered’. The findings suggest that PE may undoubtedly serve to generate positive feelings associated with physical activity and games and, in doing so, bolster some youngsters’ self-esteem and self-identities. On the other hand, however, for those less competent in sporting terms, and whose bodily self-image is not particularly positive, the public nature of PE and the nature of the activities that constitute the subject can give rise to unplanned and unintended harm to some youngsters’ mental health – especially in countries, such as Norway, where sport is a significant aspect of the group habitus and collective ‘we-group’ identity

‘Pressure to play?’ A sociological analysis of professional football managers’ behaviour towards injured players

This is an Accepted Manuscript of an article published by Taylor & Francis in Soccer and Society on 05/05/2017, available online: doi http://dx.doi.org/10.1080/14660970.2017.1321540Drawing upon figurational sociology, this paper examines professional football managers’ attitudes towards injured players. Following interviews with 10 managers, as with previous research, we found that managers have an expectancy that players are rarely fully fit. Players were stigmatised when they were seemingly unwilling to play when a manager encouraged them to. However, we also found that many managers shaped, in part, by their habitus formed from their own experiences as a player, showed greater empathy towards injured players. Many claimed they would not risk the long-term health of players, although at times, managers at the lower levels felt more constrained to take certain risks. We argue this is an unintended outcome of the increasing pressures on managers to succeed with smaller squads. The increasing emphasis and reliance on ‘sport science’ enabled managers at the higher levels to have a more supportive approach to managing injuries not previously identified in existing literature

Scoring the tumor-stroma ratio in colon cancer: procedure and recommendations

Surgical oncolog