Superconductivity and superconducting order parameter phase fluctuations in a weakly doped antiferromagnet

The superconducting properties of a recently proposed phenomenological model for a weakly doped antiferromagnet are analyzed, taking into account fluctuations of the phase of the order parameter. In this model, we assume that the doped charge carriers can't move out of the antiferromagnetic sublattice they were introduced. This case corresponds to the free carrier spectra with the maximum at ${\bf k}=(\pm \pi /2 ,\pm \pi /2)$, as it was observed in ARPES experiments in some of the cuprates in the insulating state [1]. The doping dependence of the superconducting gap and the temperature-carrier density phase diagram of the model are studied in the case of the $d_{x^{2}-y^{2}}$ pairing symmetry and different values of the effective coupling. A possible relevance of the results to the experiments on high-temperature superconductors is discussed.Comment: 16 pages, 4 figure

Magnetic and quadrupolar order in a one-dimensional ferromagnet with cubic crystal-field anisotropy

The zero temperature phase diagram of a one-dimensional S=2 Heisenberg ferromagnet with single-ion cubic anisotropy is studied numerically using the density-matrix renormalization group method. Evidence is found that although the model does not involve quadrupolar couplings, there is a purely quadrupolar phase for large values of the anisotropy. The phase transition between the magnetic and quadrupolar phases is continuous and it seems to be characterized by Ising critical exponents.Comment: 11 pages, 7 figures, REVTeX, accepted in Phys. Rev. B (scheduled on June 99

Ultra-Short-Chain PFASs in the Sources of German Drinking Water: Prevalent, Overlooked, Difficult to Remove, and Unregulated

acceptedVersio

Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of the TIR domain from the Brucella melitensis TIR-domain-containing protein TcpB

In mammals, Toll-like receptors (TLRs) recognize conserved microbial molecular signatures and induce an early innate immune response in the host. TLR signalling is mediated by interactions between the cytosolic TIR (Toll/interleukin-1 receptor) domains of the receptor and the adaptor proteins. Increasingly, it is apparent that pathogens target this interaction via pathogen-expressed TIR-domain-containing proteins to modulate immune responses. A TIR-domain-containing protein TcpB has been reported in the pathogenic bacterium Brucella melitensis. Studies have shown that TcpB interferes with the TLR2 and TLR4 signalling pathways to inhibit TLR-mediated inflammatory responses. Such interference may involve TIR-TIR-domain interactions between bacterial and mammalian proteins, but there is a lack of information about these interactions at the molecular level. In this study, the cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of the protein construct corresponding to the TIR domain of TcpB (residues 120-250) are reported. The crystals diffracted to 2.6 angstrom resolution, have the symmetry of the monoclinic space group P2(1) and are most likely to contain four molecules in the asymmetric unit. The structure should help in understanding the molecular basis of how TcpB affects the innate immunity of the host

RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation

The CCR4-NOT complex acts as a central player in the control of mRNA turnover and mediates accelerated mRNA degradation upon HDAC inhibition. Here, we explored acetylation-induced changes in the composition of the CCR4-NOT complex by purification of the endogenously tagged scaffold subunit NOT1 and identified RNF219 as an acetylation-regulated cofactor. We demonstrate that RNF219 is an active RING-type E3 ligase which stably associates with CCR4-NOT via NOT9 through a short linear motif (SLiM) embedded within the C-terminal low-complexity region of RNF219. By using a reconstituted six-subunit human CCR4-NOT complex, we demonstrate that RNF219 inhibits deadenylation through the direct interaction of the α-helical SLiM with the NOT9 module. Transcriptome-wide mRNA half-life measurements reveal that RNF219 attenuates global mRNA turnover in cells, with differential requirement of its RING domain. Our results establish RNF219 as an inhibitor of CCR4-NOT-mediated deadenylation, whose loss upon HDAC inhibition contributes to accelerated mRNA turnover

Crystallization and X-ray diffraction analysis of the C-terminal domain of the flax rust effector protein AvrM

The flax rust effector AvrM is a secreted protein of unknown fold that is recognized by the M resistance protein in flax. In order to investigate the structural basis of the AvrMM interaction and possible virulence-associated functions of AvrM, the C-terminal domains of two different AvrM variants (AvrM-A and avrM) were crystallized. Crystals of native AvrM-A were obtained using pentaerythritol ethoxylate (15/4 EO/OH) as a precipitant and diffracted X-rays to 2.9 angstrom resolution. Selenomethionine-derivative crystals of similar quality were obtained using PEG 1500 as a precipitant. Both the native and selenomethionine-labelled AvrM-A crystals had symmetry of space group C2221 with eight molecules in the asymmetric unit. Crystals of avrM had symmetry of space group P212121 and diffracted X-rays to 2.7 angstrom resolution. Initial AvrM-A phases were calculated using the single-wavelength anomalous dispersion (SAD) method and a partial model was built. Phases for avrM were obtained by molecular replacement using the partial AvrM-A model

ガーネット、サマータウン、グローバル・イシューズ案内 : 英語教材のフィクション対ノンフィクション

For the sake of the Japanese learners of English who love reading, this paper introduces three different series of readers: Garnet Oracle Readers, Summertown Readers, and National Geographic's Global Issues. Garnet Oracle and Summertown are both so-called graded readers. The former are for highschool and university students who study English as a foreign or second language while the latter are written for business people who have to learn English as a lingua franca. Both are,however, original fictional stories, some of which are quite enjoyable and really worth reading. Peter Viney, Garnet's main author, can write a variety of genres: for example, Space Romance is a romantic sci-fi story in an impressive setting; A Tidy Ghost is a witty ghost story whose terror dramatically changes into sheer humor at the ending; but,above all,his Underground is highly recommended because of the unforgettable character Tommy, a mute elderly man who lives in the London underground, saving the protagonist in big trouble. Summertown's counterpart must be James Schofield. Although his amateurish suspense stories tend to be rather boring, his humorous stories such as Room Service and Double Trouble are readable with a lot of laughter. National Geographic's Global Issues may seem to be no comparison with these interesting stories since they are serious nonfiction pamphlets edited for American high school students. Despite the foreign language, Japanese students can also appreciate the discussed, grave environmental problems of our planet Earth where the population explosion has been causing disastrous situations. In a sense, fact is truly stranger than fiction. So, which is more interesting, fiction or nonfiction? I hope you read the three series and decide for yourself

Anomalous resistivity and the electron-polaron effect in the two-band Hubbard model with one narrow band

We search for anomalous normal and superconductive behavior in the two-band Hubbard model with one narrow band. We analyze the influence of electron-polaron effect and Altshuler-Aronov effect on effective mass enhancement and scattering times of heavy and light components in the clean case. We find anomalous behavior of resistivity at high temperatures $T>W_{h}^{*}$ both in 3D and 2D situation. The SC instability in the model is governed by enhanced Kohn-Luttinger effect for p-wave pairing of heavy electrons via polarization of light electrons.Comment: 8 pages, 4 figures, accepted for publication in Journal of Superconductivity and Novel Magnetism, based on the invited talk on Stripes XI Conference in Rome, July 201

Construction of plant transformation vectors carrying beet necrotic yellow vein virus coat protein gene (ii)- plant transformation

Fragments containing the coat protein gene of beet necrotic yellow vein virus were cloned in two plant transformation vectors: pCAMBIA3301M with the bar gene as selectable marker, and pCAMBIA1304M, with resistance to hygromycin. Three constructs were made of each vector: CPL, containing coat protein gene with leader sequence; CPS with coat protein gene, and CPSas with coat protein gene in antisense orientation. Vectors pC3301MCPL, pC3301MCPS. and pC3301MCPSas were used in Agrobacterium—mediated transformation of Nicotiana tabacum (tobacco), Nicotiana excelsior and Nicotiana benthamiana. Regenerants that developed roots on selective media were tested for the presence of CP fragments and the bar gene, but most regenerants were nontransformed (50-83% escapes). After all rooted plants had been selfed, and T1 seed germinated on selective media, only plants descending from one N. excelsior regenerant transformed with pC3301MCPS were positive for presence of bar gene and CPS fragment. Tobacco and Nicotiana benthamiana were transformed with constructs pC1304MCPS and pC1304MCPSas. Transformation efficiency was much higher and approximately 50% of regenerants that rooted on media with 20 mg l−1 hygromycin were positive for the presence of CP fragments. All T1 plants were positive for presence of CP fragments