Diseño de la edificación escolar de dos niveles y pavimentación de la 16 avenida para la colonia Linda Vista, Villa Nueva, Guatemala.

Desarrollar una investigación de tipo monográfico y un diagnóstico sobre las necesidades de servicios básicos e infraestructura que servirán para el análisis de priorización de necesidades de la comunidad de la colonia Linda Vista

Insights into bootstrap percolation: Its equivalence with k-core percolation and the giant component

K-core and bootstrap percolation are widely studied models that have been used to represent and understand diverse deactivation and activation processes in natural and social systems. Since these models are considerably similar, it has been suggested in recent years that they could be complementary. In this manuscript we provide a rigorous analysis that shows that for any degree and threshold distributions heterogeneous bootstrap percolation can be mapped into heterogeneous k-core percolation and vice versa, if the functionality thresholds in both processes satisfy a complementary relation. Another interesting problem in bootstrap and k-core percolation is the fraction of nodes belonging to their giant connected components P∞b and P∞c, respectively. We solve this problem analytically for arbitrary randomly connected graphs and arbitrary threshold distributions, and we show that P∞b and P∞c are not complementary. Our theoretical results coincide with computer simulations in the limit of very large graphs. In bootstrap percolation, we show that when using the branching theory to compute the size of the giant component, we must consider two different types of links, which are related to distinct spanning branches of active nodes.Fil: Di Muro, Matias Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Físicas de Mar del Plata. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Físicas de Mar del Plata; ArgentinaFil: Valdez, Lucas Daniel. Boston University; Estados UnidosFil: Stanley, Harry Eugene. Boston University; Estados UnidosFil: Buldyrev, Sergey V.. Yeshiva University; Estados UnidosFil: Braunstein, Lidia Adriana. Politecnico di Milano; Itali

Proyecto de revalorización de fachadas para áreas periurbanas. Colonia El Coapinole. Puerto Vallarta. Jalisco. México

The article presents the advances in the project of revaluation of facades with design and chromatic intervention for peri-urban areas applied to the case study in the El Coapinole neighborhood of the city of Puerto Vallarta, Jalisco, Mexico. El artículo presenta los avances en el proyecto de revalorización de fachadas con diseño e intervención cromática para áreas periurbanas aplicado al caso de estudio en la Colonia El Coapinole de la ciudad de Puerto Vallarta, Jalisco, México. O artigo apresenta os avanços no projeto de revalorização de fachadas com desenho e intervenção cromática para áreas periurbanas aplicado ao estudo de caso no bairro El Coapinole da cidade de Puerto Vallarta, Jalisco, México.&nbsp

Immunological and clinical characteristics of latent autoimmune diabetes in the elderly

Background: Latent autoimmune diabetes in adults (LADA) is determined by both a noninsulin-dependent clinical presentation and an autoimmune pathogenic process. Glutamic acid decarboxylase antibody (GADA) constitutes the most important marker, although IA-2A and ZnT8A also define LADA presentation. Type 2 diabetes mellitus (T2DM) is the most prevalent type particularly over 65 years old. Studies about autoimmunity in this age group are scarce. Objective: The aim of this work was to determine whether three autoantibodies for diabetes autoimmunity were present in elderly T2DM patients, and to assess the distinctive clinical features of autoantibody-positive patients. Research Design and Methods: We recruited 153 patients with diabetes with onset of diabetes after 65 years of age and a BMI under 30 kg/m2. Results: The prevalence of at least one of the autoantibodies was 15.68% (24/153). The most prevalent autoantibody was GADA with 8.49% (13/153), followed by ZnT8A with 6.50% (10/153) and IA2A with 1.96% (3/153). The autoimmunity-positive group presented higher HbA1c (7.01 ± 1.98 vs 6.35 ± 1.01; P = 0.007) and more prevalent insulin therapy (25% vs 10.85%; P = 0.047). GADA-positive patients with diabetes presented higher FPG (7.79 ± 3.79 mmol/L vs 6.43 ± 1.6 mmol/L; P = 0.014) and insulin therapy more frequently (46% vs 10.71%; p = 0.015). GADA titre levels in the individuals with BMI under 27 kg/m2 were higher (35.00 ± 4.20) than those in the group with BMI over 27 kg/m2 (8.83 ± 3.041; P = 0.0005). Conclusion:: Autoantibodies GADA and Znt8A may be useful markers in identifying a subgroup of older patients with a clinical presentation of diabetes which could be characterized as latent autoimmune diabetes in the elderly.Fil: Yohena, Silvina. Hospital Sirio Libanés; Argentina. Fundación Barceló. Instituto Universitario de Ciencias de la Salud; ArgentinaFil: Penas Steinhardt, Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Barceló. Instituto Universitario de Ciencias de la Salud; Argentina. Universidad Nacional de Luján; ArgentinaFil: Muller, Clara. Hospital Sirio Libanés; ArgentinaFil: Faccinetti, Natalia Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Inmunología, Genética y Metabolismo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Cerrone, Gloria Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Inmunología, Genética y Metabolismo; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Lovecchio, Silvia. Hospital Sirio Libanés; Argentina. Fundación Barceló. Instituto Universitario de Ciencias de la Salud; ArgentinaFil: Ridner, Alberrto Edgardo. Fundación Barceló. Instituto Universitario de Ciencias de la Salud; ArgentinaFil: Valdez, Silvina Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Frechtel, Gustavo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Inmunología, Genética y Metabolismo; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Hospital Sirio Libanés; Argentina. Fundación Barceló. Instituto Universitario de Ciencias de la Salud; Argentin

Size selectivity and optimal soaking time of hoops and traps targeting the blue swimming crab Callinectes arcuatus in Cuyutlan Lagoon, Mexico

The selectivity of two types of commercial fishing gear (crab hoop/traditional gear and rigid rectangular cage traps) targeting blue crabs (Callinectes arcuatus) in Cuyutlan Lagoon, Mexico, was assessed. The effect of soak time on crab catches versus the retention and escape rate of organisms was also evaluated. Results suggested that traps captured larger individuals than hoops. The carapace width of crabs was significantly different between the fishing gears used: 63.9% of crabs caught with hoops were < 95 mm (sizes ranged from 40 to 113 mm) and 40.7% of crabs caught with traps were < 95 mm (range: 49 to 120 mm). Results also showed that catch rates were high during the first two hours and decreased after the third hour. The crabs tended to escape after several hours of soak time. The study found that the traps captured larger crabs than the hoops, suggesting that traps are a suitable fishing gear for catching blue swimming crabs in Cuyutlan Lagoon

Análisis de las características de las antenas logoperiódica y fractal, impresas, en la banda "L" y "S"

Se propone el diseño de dos antenas, denominadas logoperiódica y fractal, ambas impresas, en las bandas de frecuencia L (1-2 GHz) y S (2-4 GHz) y por medio de la simulación conocer las prestaciones con relación al diagrama de radiación, respuesta en frecuencia dentro el ancho de banda previsto, ROE, impedancia de entrada, etc. El objeto es realizar una comparación entre las mismas para determinar la de mejor performance y ser instalada en el equipo electrónico portátil monitor de radiaciones no ionizantes en las bandas de frecuencias "L" y "S". El requerimiento del proyecto impone que la construcción sea compacta y de tamaño reducido, para poder ser utilizada en el dispositivo autónomo antes mencionado. El desarrollo de las antenas impresas y la selección de la más conveniente, integra el Proyecto de Desarrollo Tecnológico y Social ―Diseño y construcción de un equipo electrónico portátil monitor de radiaciones no ionizantes en las bandas de frecuencias "L" y "S"Facultad de Ingenierí

Analysis of surface roughness of different woods in the provinces of Pinar del Rio and Artemisa, Cuba

The objective of this work was to the characteristics of the planing tests on the wood of Pinus caribaea Morelet var. caribaea Barret and Golfari, Acacia mangium Willd, Gmelina arborea Roxb, Samanea saman (Jacq.) Merril and Eucalyptus saligna Sm. The study material was obtained in plantations located in the agroforestry companies Pinar del Rio, Macurije and Costa Sur in the provinces of Pinar del Rio and Artemisa, Cuba. The planning tests, the evaluation of defects and classification were carried out according to ASTM D-1666-2004 and DIN/ISO 1302:2002.ASTM D-1666-2004 and Norma DIN/ISO 1302. In general, the woods studied were classified as species with excellent workability, so they can be used in the production of products with higher added value

Estrutura populacional e agentes polinizadores de Catasetum ochraceum nas rocas da cordilheira ocidental (La Vorágine, Colômbia)

Catasetum ochraceum is a terrestrial orchid with discontinuous distribution in Colombia and Venezuela. A population was monitored for four years in La Vorágine, Valle del Cauca, Colombia. Pollination observations were made, as well as a census of individuals in the population was carried out. Catasetum spp is known to be pollinated by male euglossine bees, so to identify local pollinators, traps were located with attractants 1-8 cineol and methyl salicylate to collect bees with Catasetum polynaries. A total of 50 individuals were recorded, measured and mapped for follow-up from 2016 to 2020. During the observation period, no marked plants produced fruit and 22 plants survived until the end of the sampling. As for the collection of bees, 18 specimens of eight different species were recorded: Eulema nigrita, Exaerete smaragdina, Euglossa despecta, Eg. ignita, Eg. modestior, Eg. tridentata, Eg. deceptrix and Eg. liopoda. From these, Eg. deceptrix and Eg. liopoda carried polynaries of C. ochraceum. Therefore it is concluded that this population of orchids could be threatened, but the reasons for the population decline are unknown. In addition, two potential pollinator species are identified in the study area.Catasetum ochraceum es una orquídea terrestre con distribución discontinua en Colombia y Venezuela. Una población fue monitoreada durante cuatro años en La Vorágine, Valle del Cauca, Colombia. Se realizaron observaciones de polinización y se hizo un censo de los individuos de la población. Se sabe que las Catasetum spp son polinizadas por abejas euglosinas machos, así que para identificar los polinizadores locales ubicamos trampas con los atrayentes 1-8 cineol y salicilato de metilo para colectar abejas con polinarios de Catasetum. Un total de 50 individuos fueron registrados, medidos y mapeados para hacerles seguimiento desde 2016 hasta 2020. Durante el periodo de observación, ninguna planta marcada produjo frutos y 22 plantas sobrevivieron hasta el final del muestreo. En cuanto a la colecta de abejas, 18 especímenes de ocho especies diferentes fueron registrados: Eulema nigrita, Exaerete smaragdina, Euglossa despecta, Eg. ignita, Eg. modestior, Eg. tridentata, Eg. deceptrix y Eg. liopoda. De estas, Eg. deceptrix y Eg. liopoda portaron polinarios de C. ochraceum. Se concluye que esta población de orquídeas podría estar amenazada, pero se desconocen las razones del declive poblacional. Además, se identifican dos especies de polinizadores potenciales en la zona de estudio.Catasetum ochraceum é uma orquídea terrestre com distribuição descontínua na Colômbia e na Venezuela. Uma população foi monitorada durante quatro anos em La Vorágine, Valle del Cauca, Colômbia. Foram realizadas observações de polinização e foi feito um censo dos indivíduos da população. Sabe-se que as Catasetum spp são polinizadas por abelhas Euglossini machos (“abelhas das orquídeas”), assim que, para identificar os polinizadores locais, localizamos armadilhas com os atraentes 1-8 cineol e salicilato de metilo para coletar abelhas com polinários de Catasetum. Um total de 50 indivíduos foram registrados, medidos e mapeados para fazer acompanhamento desde 2016 até 2020. Durante o período de observação, nenhuma planta marcada produziu frutos e 22 plantas sobreviveram até o final da amostra. Quanto à coleta de abelhas, 18 espécimenes de oito espécies diferentes foram registrados: Eulema nigrita, Exaerete smaragdina, Euglossa despecta, Eg. ignita, Eg. modestior, Eg. tridentata, Eg. deceptrix e Eg. liopoda. Destas, Eg. deceptrix e Eg. liopoda portaram polinários de C. ochraceum. Conclui-se que essa população de orquídeas poderia estar ameaçada, mas são desconhecidas as razões da decadência populacional. Além disso, duas espécies são identificadas de polinizadores potenciais na zona de estudo

Beta cell autoimmunity in elederly with type 2 diabetes: clinical, metabolic and therapeutic impact

Introducción: se estudiaron 111 pacientes con diabetes diagnosticada después de los 65 ó más años de edad no obesos (IMC<30 kg/m2 ). Materiales y métodos: se determinaron cuatro anticuerpos marcadores de autoinmunidad para células ß pancreáticas: GADA, ZnT8, IA2A y PAA. Se midieron variables metabólicas, bioquímicas, antropométricas, clínicas y terapéuticas. Resultados: el 32% de los pacientes presentó autoanticuerpos. El autoanticuerpo más hallado fue el PAA 58,3%, seguido del GADA 30,5%, el ZnT8 27,7% y el IA2A 5,5%. Los pacientes con anticuerpos presentaron mayor circunferencia de cintura, insulinorresistencia (HOMA-IR), secreción de insulina (HOMAß) y complicaciones microangiopáticas. Entre ellos también fue más común que requirieran de insulina pero la diferencia no fue significativa. Conclusiones: estos resultados son diferentes de los que se esperaría tanto en diabéticos 2 como en diabéticos LADA más jóvenes, lo que sugiere que esta población tendría rasgos fenotípicos particulares y merece ser analizada con mayor extensión y profundidad. Proponemos la denominación LADE (latent autoimmune diabetes in elderly) para estos pacientes mayores de 65 años no obesos DM2 Au+.Introduction: 111 non-obese patients with diabetes diagnosed after the age of 65 (BMI <30,0 kg/m2 ), were studied. Material and methods: GADA, ZnT8, IA2a and PAA, four antibody markers for pancreatic ß cell autoimmunity were determined. Personal and familiar history of diabetes and autoimmune diseases were collected, and metabolic, biochemical, anthropometric, clinical and therapeutic variables were measured. Results: 32% of patients had at least one antibody. The most frequent antibody was PAA (58,3%), followed by GADA (30,5%), ZnT8 (27,7%) and IA2A (5,5%). Patients with antibodies had greater waist circumference, greater insulin resistance and ß cell function and higher prevalence of microangiopathic alterations. Insulin requirement was larger for patients with antibodies but differences were not significant. Conclusions: these results are different from those that would be expected in both type 2 diabetes and LADA, suggesting that this population may have particular phenotype features; thus, the issue needs further analysis. We propose the name LADE (Latent Autoimmune Diabetes in Elderly) for these patients over 65 years non-obese DM2 Au+.Fil: Ridner, Alberrto Edgardo. Hospital Sirio Libanes; ArgentinaFil: Yohena, Silvana Valeria. Hospital Sirio Libanes; ArgentinaFil: Tornelli, Facundo Alejandro. Hospital Sirio Libanes; ArgentinaFil: Muller, Clara. Hospital Sirio Libanes; ArgentinaFil: Diaz, Silvina. Hospital Sirio Libanes; ArgentinaFil: Lovecchio, Silvia. Hospital Sirio Libanes; ArgentinaFil: Faccinetti, Natalia Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Estudios de la Inmunidad Humoral Prof. Ricardo A. Margni. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Estudios de la Inmunidad Humoral Prof. Ricardo A. Margni; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Inmunología; ArgentinaFil: Penas Steinhart, Alberto. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Inmunología; ArgentinaFil: Valdez, Silvina Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Estudios de la Inmunidad Humoral Prof. Ricardo A. Margni. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Estudios de la Inmunidad Humoral Prof. Ricardo A. Margni; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Inmunología; ArgentinaFil: Guerra, Luciano Lucas. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Estudios de la Inmunidad Humoral Prof. Ricardo A. Margni. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Estudios de la Inmunidad Humoral Prof. Ricardo A. Margni; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Inmunología; ArgentinaFil: Frechtel, Gustavo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Hospital Sirio Libanes; Argentin

Global, regional, and national burden of chronic kidney disease, 1990–2017 : a systematic analysis for the Global Burden of Disease Study 2017

Background Health system planning requires careful assessment of chronic kidney disease (CKD) epidemiology, but data for morbidity and mortality of this disease are scarce or non-existent in many countries. We estimated the global, regional, and national burden of CKD, as well as the burden of cardiovascular disease and gout attributable to impaired kidney function, for the Global Burden of Diseases, Injuries, and Risk Factors Study 2017. We use the term CKD to refer to the morbidity and mortality that can be directly attributed to all stages of CKD, and we use the term impaired kidney function to refer to the additional risk of CKD from cardiovascular disease and gout. Methods The main data sources we used were published literature, vital registration systems, end-stage kidney disease registries, and household surveys. Estimates of CKD burden were produced using a Cause of Death Ensemble model and a Bayesian meta-regression analytical tool, and included incidence, prevalence, years lived with disability, mortality, years of life lost, and disability-adjusted life-years (DALYs). A comparative risk assessment approach was used to estimate the proportion of cardiovascular diseases and gout burden attributable to impaired kidney function. Findings Globally, in 2017, 1·2 million (95% uncertainty interval [UI] 1·2 to 1·3) people died from CKD. The global all-age mortality rate from CKD increased 41·5% (95% UI 35·2 to 46·5) between 1990 and 2017, although there was no significant change in the age-standardised mortality rate (2·8%, −1·5 to 6·3). In 2017, 697·5 million (95% UI 649·2 to 752·0) cases of all-stage CKD were recorded, for a global prevalence of 9·1% (8·5 to 9·8). The global all-age prevalence of CKD increased 29·3% (95% UI 26·4 to 32·6) since 1990, whereas the age-standardised prevalence remained stable (1·2%, −1·1 to 3·5). CKD resulted in 35·8 million (95% UI 33·7 to 38·0) DALYs in 2017, with diabetic nephropathy accounting for almost a third of DALYs. Most of the burden of CKD was concentrated in the three lowest quintiles of Socio-demographic Index (SDI). In several regions, particularly Oceania, sub-Saharan Africa, and Latin America, the burden of CKD was much higher than expected for the level of development, whereas the disease burden in western, eastern, and central sub-Saharan Africa, east Asia, south Asia, central and eastern Europe, Australasia, and western Europe was lower than expected. 1·4 million (95% UI 1·2 to 1·6) cardiovascular disease-related deaths and 25·3 million (22·2 to 28·9) cardiovascular disease DALYs were attributable to impaired kidney function. Interpretation Kidney disease has a major effect on global health, both as a direct cause of global morbidity and mortality and as an important risk factor for cardiovascular disease. CKD is largely preventable and treatable and deserves greater attention in global health policy decision making, particularly in locations with low and middle SDI