Flash-Mold Machine for Manufacturing Drug Implants

This Final Project Report provides the reader with a comprehensive detailing of all of the actions and work that has been completed for this Senior Design Project. In this report, the Cal Poly Biomedical Engineering Senior Project Team will discuss some background on the existing Mark I Flash-Mold Machine currently in use by Gesea Biosciences, background information on Gesea Biosciences, the Customer Requirements and Design Specifications of the new machine, Quality Engineering considerations, design concepts discussed, design concepts chosen, safety considerations, prototype development, manufacturing, testing protocols, and testing results, etc

Study of fluid layer gravity motion over vertical surface

This paper presents the results of studying the motion of a liquid layer along the walls of a vertically installed pipe under the action of gravity. Two-dimensional boundary layer is formed by the fluid motion relative to the hard wall on surfaces of structures (pipes, turbines, heat-and-mass transfer equipment, aircrafts, ships, etc.), which are of positive interest in engineering practice. Further upgrading of the above-mentioned structures is possible only by increasing accuracy of momentum in the boundary layer, heat and mass transfer rates calculation. It is confirmed that in the boundary layer transfer phenomena intensity (perpendicular to the wall) is due to the fluid particles velocity distribution regularities in the cross-section of the layer. Fluid velocity distribution regularities in turn are conditioned by Reynolds number according to current notions. The principal method of quantitative analysis of turbulent flow in a boundary layer suggested by Reynolds continues to be the velocity and pressure fluctuations averaging method for some timespan. The suggested model of fluid movement enables to prognosticate conditions under which in cross-sections of the boundary layer reshaping of velocity profile takes place, to carry out analytic calculation of such hydrodynamic characteristics as mean velocity of motion, layer thickness and shearing stresses acting on the wall. The difference between the suggested methods developed for calculation of flow parameters from the well-known ones is in that that calculations are made based on an integrated approach regardless of such conceptual definitions as laminar and turbulent regimes widely used in modern hydrodynamics. Obtained results and design formulas known in the literature have been compared. It has been found that the thickness of the sliding layer, determine by the proposed calculation formula, 1.17 times smaller than that determined by the currently used formul

Taylor, Monique. 2022. China’s Digital Authoritarianism. Politics and Development of Contemporary China. Palgrave Macmillan, Cham. XVII, 169 pp. https://doi.org/10.1007/978-3-031-11252-2

This book examines the problem of modern Chinese digital authoritarianism, as well as the key global process of modern development, covering various areas of public life. The characteristic features of the global and regional trends in the digitalization of society are identified and described, which modernize the task of adapting political regimes to new network conditions both in China and in other authoritarian countries. This, in turn, raises the question of the need for a comprehensive comparative analysis of cases of legitimation of different political regimes in order to develop a package of recommendations for the effective transformation of the modern Chinese political regime. The most difficult scientific problem is, first of all, the definition of deep transformations of social and political reality under the pressure of forced digitalization. Other problems actualize the chosen research topic: the risks and threats of information wars, politicized fakes, attempts to distort historical memory, which can trigger the processes of delegitimization of the political regime. At the same time, digitalization gives political regimes additional prospects in terms of the use of social networks by government bodies, the transformation of communication models of the ruling parties. China’s digital technologies are research topics in political science and international relations that affect the quality and effectiveness of governance. In this regard, time and reflective ways of theorizing about digital technologies in international relations are important. The author focuses on the analysis of the role of technological continuity and changes in China, which today has practically no proven approaches to studying the impact of digitalization and big data on international relations

Model assessment of the effects of land use change on hydrologic response

The effect of landuse change on the hydrologic, biogeochemical and ecological response of watersheds is a concern throughout the world. To help characterize the potential magnitude of such changes, and of the potential to remediate or avoid undesirable features, studies focused on the cumulative watershed effects of site level change are necessary. The current state of the art model for water quality in agricultural lands, Soil Water Assessment Tool (SWAT), was used to estimate the effects of a set of future landscape scenarios on water quality in the Corn Belt region of the United States. These results indicated that changes to the current water quality management strategies will be necessary to significantly improve water quality in the Corn Belt region. In addition, the experience of implementing SWAT suggested a variety of changes to the model structure and study design with potential to improve the quality of the results. These changes include improved treatment of hydrologic process, full integration of input data and model code, different methods of distributing data across space, the use of fewer parameters, more sophisticated numerical techniques, and improved methods for generating potential landscape scenarios. A new model structure (WET_Hydro) was developed to address these issues. The hydrologic components of the model focus on a conceptual physically based characterization of the movement of water in soils, as overland flow, and in channels. Tests using a variety of input data sets, including both synthetic inflows and real watershed data were developed to verify the hydrologic components of the model. Additional model analyses evaluate how model scale interacts with parameters and with measurements. These analyses point toward additional criteria that may prove useful to the determination of correct model scales and to the utility of the flexible model structure which provides automatic changes to model scale. In addition to the scale analysis, a method of estimating the average new water contribution to storm discharge was developed.. This additional model criterion was shown to provide further understanding of model utility under different hydrologic regimes. The hydrologic model was extended to produce estimates of erosion and sediment export. Sensitivity to various restoration options were developed focusing on simple descriptions of remediation potential, and a minimum of parameters. In addition, the water quality model was coupled with a Decision Support System (DSS). Example applications demonstrate the potential of the combination to improve the process of restoration planning at the watershed scale

Seclin – Voirie et réseaux de distribution de la ZAC de l’Épinette

Date de l'opération : 1991 (PR) Inventeur(s) : Révillion Stéphane ; Vache A. ; Foubert R L’aménagement d’une ZAC dite de l’Épinette, au nord de la commune de Seclin, est à l’origine des prospections entreprises sur le versant sud du dôme crayeux du Mélantois, dans le prolongement de la déviation nord de Seclin, en bordure de l’autoroute A1 (Paris-Lille). En raison de l’ampleur du projet (60 ha), les travaux archéologiques ont été limités à la voirie et aux réseaux de distribution (10 km liné..

Seclin – Voirie et réseaux de distribution de la ZAC de l’Épinette

Date de l'opération : 1991 (PR) Inventeur(s) : Révillion Stéphane ; Vache A. ; Foubert R L’aménagement d’une ZAC dite de l’Épinette, au nord de la commune de Seclin, est à l’origine des prospections entreprises sur le versant sud du dôme crayeux du Mélantois, dans le prolongement de la déviation nord de Seclin, en bordure de l’autoroute A1 (Paris-Lille). En raison de l’ampleur du projet (60 ha), les travaux archéologiques ont été limités à la voirie et aux réseaux de distribution (10 km liné..

Coupling Biophysical Processes and Water Rights To Simulate Spatially Distributed Water Use in an Intensively Managed Hydrologic System

Humans have significantly altered the redistribution of water in intensively managed hydrologic systems, shifting the spatiotemporal patterns of surface water. Evaluating water availability requires integration of hydrologic processes and associated human influences. In this study, we summarize the development and evaluation of an extensible hydrologic model that explicitly integrates water rights to spatially distribute irrigation waters in a semi-arid agricultural region in the western US, using the Envision integrated modeling platform. The model captures both human and biophysical systems, particularly the diversion of water from the Boise River, which is the main water source that supports irrigated agriculture in this region. In agricultural areas, water demand is estimated as a function of crop type and local environmental conditions. Surface water to meet crop demand is diverted from the stream reaches, constrained by the amount of water available in the stream, the waterrights- appropriated amount, and the priority dates associated with particular places of use. Results, measured by flow rates at gaged stream and canal locations within the study area, suggest that the impacts of irrigation activities on the magnitude and timing of flows through this intensively managed system are well captured. The multi-year averaged diverted water from the Boise River matches observations well, reflecting the appropriation of water according to the water rights database. Because of the spatially explicit implementation of surface water diversion, the model can help diagnose places and times where water resources are likely insufficient to meet agricultural water demands, and inform future water management decisions

Abflussprozesse auf der Mesoskala? - Grenzen und Moeglichkeiten multivariater Tracer Methoden

Auf Grundlage von hydrochemischen Zeitreihen wurden tracer basierte Mischungsmodelle zur Ableitung von Abflussprozessen zwischen Teileinzugs-gebieten des Dill-Einzugsgebiets (Hessen) miteinander verglichen. Hierzu wurden die Grundwasserabfluesse von Teileinzugsgebieten mit Einzugsgebietseigenschaften, wie mittlere Hangneigung, in Beziehung gesetzt. Die Ergebnisse zeigen, dass die Wahl der Tracerkombinationen und die Metrik der Tracerdaten (z.B. PCA) einen erheblichen Einfluss auf die Aussage zu den Einflussgroessen des hydrologischen Verhaltens eines Einzugsgebiets haben