Maldades de las brujas puertorriqueñas

Este artículo describe algunas de las creencias que existen en la tradición folclórica de Puerto Rico acerca de las brujas. Sobre todo, acerca de sus actividades destructoras y maléficas en relación con los seres humanos, y sobre sus potencias mágicas.This paper describes some of the beliefs about witches that exsist in the folk tradition of Puerto Rico, focusing specially in their destructive and harmful actions against humans, and in their magical powers

Maldades de las brujas puertorriqueñas

Este artículo describe algunas de las creencias que existen en la tradición folclórica de Puerto Rico acerca de las brujas. Sobre todo, acerca de sus actividades destructoras y maléficas en relación con los seres humanos, y sobre sus potencias mágicas.This paper describes some of the beliefs about witches that exsist in the folk tradition of Puerto Rico, focusing specially in their destructive and harmful actions against humans, and in their magical powers

Implementación de Enterprise Performance Management para la planificación presupuestal de Business & Decision LATAM

Este proyecto consiste en la implementación de Enterprise Performance Management para poder optimizar de control presupuestal de la consultora Business & Decision LATAM (B&D LATAM), así mismo, centralizar el control operativo de la asignación de recursos (Consultores) y margen de contribución que tiene cada proyecto a implementarse. Para lograr la implementación nos apoyaremos de la metodología de proyectos BIP (Business & Decision Initiative for Performance) personalizada, definida por la división de Calidad de Software de B&D LATAM. El principal resultado obtenido fue la mejora de la capacidad de gestionar y controlar el proceso presupuestal y proyecciones que brinda la herramienta EPM. Los resultados de este proyecto demuestran la gran utilidad que este tipo de herramientas representa al permitir discriminar la producción efectiva de cada consultor y de cuánto tiempo tiene sin afectación a un proyecto durante su estadía en la compañía. Este proyecto permite concluir que el control presupuestal eficiente en una organización consultora de sistemas posibilita el ahorro de costos al administrar adecuadamente las contrataciones de nuevo personal, y de la gestión de cumplimiento de objetivos comerciales. Este proyecto también demuestra la gran flexibilidad y capacidad del motor de cálculo de la herramienta Hyperion Planning, permitiendo tener como resultado un estado de ganancias y pérdidas que permita la salud financiera de la compañía

Aplicación del enfoque interactivo para mejorar la comprensión lectora en los estudiantes de 4to grado de Educación Primaria en la I.E.P. N° 16388 del Centro Poblado "Francisco Bolognesi" San Ignacio 2014

El presente trabajo de investigación denominado: “Aplicación del Enfoque Interactivo para Mejorar la Comprensión Lectora en los Estudiantes de 4° Grado de Educación Primaria en la I.E.P. N° 16388 del Centro Poblado Francisco Bolognesi, San Ignacio – 2014”; tuvo como objetivo general: Demostrar que la aplicación de estrategias didácticas en base al enfoque interactivo conlleva a mejorar la comprensión lectora en los estudiantes del 4° Grado de Educación Primaria en la I.E.P. N° 16388 del Centro Poblado “Francisco Bolognesi”, San Ignacio - 2014. La investigación fue ejecutada en la Institución Educativa N° 16388 del Centro Poblado Francisco Bolognesi - San Ignacio. Su diseño fue pre experimental de tipo aplicativo – explicativo, en el que se utilizó un pre test y un post test con un grupo experimental. Se trabajó con una población y muestra de 21 estudiantes del 4° grado de educación primaria, y para el recojo de datos fue aplicada una encuesta que sirvió de pre test y post test, para evaluarlo antes y después de aplicado el programa. Se consideró a la Institución Educativa San Luis Gonzaga Fe y Alegría Nº 22 como centro piloto referente para la validación del constructo del Instrumento. Del análisis de las tablas y gráficos estadísticos de la investigación realizada arrojó los siguientes resultados: se observa que los estudiantes en su mayoría se sitúan en logro previsto con el 61.91% en el nivel literal, 42.86% en el nivel inferencial y 47.63 en el nivel crítico y también ya se observa porcentajes en el logro destacado. Esto indica que la utilización del enfoque interactivo repercutió favorablemente en mejorar la comprensión de los 21 estudiantes

Hepatotoxicity induced by isoniazid in patients with latent tuberculosis infection: a meta-analysis

Adverse drug reaction; Latent tuberculosis; Liver injuryReacción adversa a medicamentos; Tuberculosis latente; Lesión hepáticaReacció adversa a medicaments; Tuberculosi latent; Lesió hepàticaAim: The aim of the present study was to conduct a meta-analysis of the frequency of isoniazid-induced liver injury (INH-ILI) in patients receiving isoniazid (INH) preventative therapy (IPT). Background: The frequency of hepatotoxicity (drug-induced liver injury: DILI) of antituberculosis drugs has been studied, especially when INH, rifampin, and pyrazinamide are co-administered. However, little is known about the frequency of DILI in patients with latent tuberculosis infection (LTBI), where IPT is indicated. Methods: We searched PubMed, Google Scholar, and the Cochrane Database of Systematic Reviews for studies reporting the frequency of INH-ILI in patients with IPT using one or more diagnostic indicators included in the criteria of the DILI Expert Working Group. Results: Thirty-five studies comprising a total of 22,193 participants were included. The overall average frequency of INH-ILI was 2.6% (95% CI, 1.7-3.7%). The mortality associated with INH-DILI was 0.02% (4/22193). Subgroup analysis revealed no significant differences in the frequency of INH-ILI in patients older or younger than 50 years, children, patients with HIV, candidates for liver, kidney, or lung transplant, or according to the type of study design. Conclusion: The frequency of INH-ILI in patients receiving IPT is low. Studies on INH-ILI are needed where the current DILI criteria are used

<i>Gaia</i> Data Release 1. Summary of the astrometric, photometric, and survey properties

Context. At about 1000 days after the launch of Gaia we present the first Gaia data release, Gaia DR1, consisting of astrometry and photometry for over 1 billion sources brighter than magnitude 20.7. Aims. A summary of Gaia DR1 is presented along with illustrations of the scientific quality of the data, followed by a discussion of the limitations due to the preliminary nature of this release. Methods. The raw data collected by Gaia during the first 14 months of the mission have been processed by the Gaia Data Processing and Analysis Consortium (DPAC) and turned into an astrometric and photometric catalogue. Results. Gaia DR1 consists of three components: a primary astrometric data set which contains the positions, parallaxes, and mean proper motions for about 2 million of the brightest stars in common with the HIPPARCOS and Tycho-2 catalogues – a realisation of the Tycho-Gaia Astrometric Solution (TGAS) – and a secondary astrometric data set containing the positions for an additional 1.1 billion sources. The second component is the photometric data set, consisting of mean G-band magnitudes for all sources. The G-band light curves and the characteristics of ∼3000 Cepheid and RR-Lyrae stars, observed at high cadence around the south ecliptic pole, form the third component. For the primary astrometric data set the typical uncertainty is about 0.3 mas for the positions and parallaxes, and about 1 mas yr−1 for the proper motions. A systematic component of ∼0.3 mas should be added to the parallax uncertainties. For the subset of ∼94 000 HIPPARCOS stars in the primary data set, the proper motions are much more precise at about 0.06 mas yr−1. For the secondary astrometric data set, the typical uncertainty of the positions is ∼10 mas. The median uncertainties on the mean G-band magnitudes range from the mmag level to ∼0.03 mag over the magnitude range 5 to 20.7. Conclusions. Gaia DR1 is an important milestone ahead of the next Gaia data release, which will feature five-parameter astrometry for all sources. Extensive validation shows that Gaia DR1 represents a major advance in the mapping of the heavens and the availability of basic stellar data that underpin observational astrophysics. Nevertheless, the very preliminary nature of this first Gaia data release does lead to a number of important limitations to the data quality which should be carefully considered before drawing conclusions from the data

Evaluation of the Timed Up and Go test for screening vulnerability and frailty in older cancer patients

Introduction. The need for comprehensive geriatric assessment (CGA) in older adults with cancer is increasing, which makes it necessary to have a screening instrument to identify those who would benefit from this evaluation. This study aimed to investigate diagnostic performance of the Timed Up and Go test (TUG) for identifying vulnerable or frail older adults with cancer who might benefit from CGA.  Material and methods. This observational and retrospective study took place at the geriatric center of Almenara Hospital in Lima, Peru. We extracted CGA reports from electronic medical records of outpatients and inpatients aged 60 years and older with cancer, who were evaluated between November 2022 and July 2023. Patients were classified based on SIOG-2 (International Society of Geriatric Oncology) criteria as fit, vulnerable, or frail, based on scales including Activities of Daily Living (ADL), Instrumental ADL, Mini-Nutritional Assessment (MNA), Mini-Mental State Exam (MMSE), Geriatric Depression Scale, and Cumulative Illness Rating Scale-Geriatrics (CIRS-G). For the study, two groups were formed: fit patients and non-fit patients (vulnerable plus frail). We estimated sensitivity, specificity, and positive predictive values of the TUG test. The accuracy of the TUG test was analyzed using the area under the receiver operating characteristic curve (AUC).  Results. Among the 283 included patients, 154 were men (54.4%) and 129 women (45.6%), and the mean age was 76.8 ± 15.8 years. The most common neoplasms were colorectal (19.4%), stomach (15.2%), prostate (9.9%), and bile duct cancers (8.1%). The percentage of fit and non-fit patients was 21.9% and 78.1%, respectively. When the TUG test was equal to or greater than 15.5 seconds, sensitivity, specificity, positive predictive value, and AUC were 68.5% (95% CI 61.9–74.5), 88.5% (77.8–95.3), 95.6% (91.1–98.2), and 84.8% (0.80–0.90), respectively.  Conclusions. A TUG test result equal to or greater than 15.5 seconds demonstrated good screening properties for identifying older cancer patients who were vulnerable or frail and could benefit from CGA