Three rare lignicolous fungi from Sicily (S Italy)

Sarcodontia crocea (Schwein.) Kotl., Oligoporus mappa (Overh. & Lowe) Gilbn. & Ryvarden and Inonotus rickii (Pat.) D.A. Reid. are reported for the first time from Sicily (southern Italy). Ecological and distributive features on the three relevant species are also here provided

Two Rare Northern Entoloma Species Observed in Sicily under Exceptionally Cold Weather Conditions

The biology and ecology of many Entoloma species is still poorly known as well as their geographical distribution. In Italy, there are no studies on the influence of weather on fungal abundance and richness and our knowledge on the ecology and distribution of Entoloma species needs to be improved. The discovery of two Entoloma species in Sicily (southern Italy), reported in the literature as belonging to the habitat of north European countries, was the basis leading to the assumption that anomalous climatic conditions could stimulate the growth of northern entolomas in the southernmost Mediterranean regions. The results of this study show that the presence of northern Entoloma species in Sicily is not influenced by the Mediterranean type of vegetation, by edaphic or altitudinal factors but by anomalous climatic trends of precipitations and temperatures which stimulate the fructification of basidiomata in correspondence with a thermal shock during autumn

Three rare lignicolous fungi from Sicily (S Italy)

Sarcodontia crocea (Schwein.) Kotl., Oligoporus mappa (Overh. & Lowe) Gilbn. & Ryvarden and Inonotus rickii (Pat.) D.A. Reid. are reported for the first time from Sicily (southern Italy). Ecological and distributive features on the three relevant species are also here provided

Tamarix arborea var. arborea and Tamarix parviflora: Two species valued for their adaptability to stress conditions

The choice of stress resistant and highly adaptable species is a fundamental step for landscaping and ornamental purposes in arid and coastal environments such as those in the Mediterranean basin. The genus Tamarix L. includes about 90 species with a high endurance of adversity. We investigated the water relations and photosynthetic response of Tamarix arborea (Sieb. ex Ehrenb.) Bge. var. arborea and T. parviflora DC. growing in an urban environment. Both species showed no evidence of drought or salt stress in summer, and appeared to follow two strategies with T. arborea var. arborea investing in high carbon gain at the beginning of the summer, and then reducing photosynthetic activity at the end of the season, and T. parviflora showing lower but constant levels of photosynthetic activity throughout the vegetative season. For landscaping and ornamental purposes, we suggest T. arborea var. arborea when a fast-growing, high-cover species is necessary, and T. parviflora when less-invasive species are required

INFLUENCE OF FELDENKRAIS METHOD ON SPINE HEALTH IN PROFESSIONAL ORCHESTRAL MUSICIANS. PILOT STUDY/INFLUENZA DEL METODO FELDENKRAIS SULLA SALUTE DEL RACHIDE IN MUSICISTI ORCHESTRALI PROFESSIONISTI. STUDIO PILOTA

Obiettivo: Lo scopo di questo studio è stato quello di esaminare se il Metodo Feldenkrais fosse utile per migliorare la flessibilità muscolare e ridurre il dolore alla schiena in musicisti orchestrali professionisti. Materiali e metodi: Diciassette partecipanti sono stati reclutati da un orchestra sinfonica di Palermo (Italia) e divisi casualmente in un gruppo di controllo (C, n = 8) e un gruppo Feldenkrais (F, n = 9). Il primo non ha partecipato al protocollo Feldenkrais e a qualsiasi altra attività fisica; mentre il secondo ha preso parte ad un programma costituito da quattro lezioni di gruppo di Consapevolezza Attraverso il Movimento (CAM) eseguito 2 ore alla settimana per 4 settimane. Al fine di valutare lo stato di salute della colonna vertebrale, abbiamo usato il sit-and-reach test ed il trunk lift test. Le differenze all'interno di ogni gruppo e tra il gruppo C e il gruppo F sono state rispettivamente esaminate con il test di Wilcoxon e quello di Mann-Whitney; e considerate significative con p ≤ 0,05. Risultati: La flessibilità muscolare del bicipite femorale e della regione lombare, e la forza, la flessibilità e la resistenza dei muscoli estensori del tronco era leggermente aumentata nel gruppo F rispetto al gruppo C dopo il protocollo Feldenkrais; anche se questa variazione non era statisticamente significativa. Diversamente, il gruppo C ha mostrato una riduzione del 5% in entrambi i test dopo 4 settimane. Dopo il protocollo Feldenkrais, l’altezza del gruppo F era significativamente maggiore rispetto a prima del trattamento. Inoltre, abbiamo trovato che il numero dei partecipanti, che hanno dichiarato di avere dolore forte e frequente alla schiena e agli arti, diminuiva durante il periodo di svolgimento del protocollo Feldenkrais. Questo effetto era maggiore nella regione cervicale rispetto a quella lombare e agli arti superiori. Conclusioni: I nostri risultati mostrano che il Metodo Feldenkrais ha effetti positivi sulla flessibilità muscolare e supporta l'uso di questo metodo per sciogliere le tensioni e le contrazioni muscolari che possono causare dolore nei musicisti orchestrali professionisti.Objectives: The aim of this study was to explore whether Feldenkrais Method was useful for improving muscular flexibility and reducing back pain in professional orchestral musicians. Materials and methods: Seventeen participants were recruited from a symphony orchestra of Palermo (Italy) and randomly divided in a control group (C, n=8) and a Feldenkrais group (F, n=9). The first didn’t participate in the Feldenkrais protocol and any other physical activity; while the second took part into a program consisting of four Awareness through movement (ATM) classes performed 2 hours/week for 4 weeks. In order to assess muscle fitness of spine, we used sit-and-reach and trunk lift test. The differences within each group and between C and F groups were respectively examined with Wilcoxon matched pair test and Mann-Whitney test; and considered significant with p≤0.05. Results: The muscular flexibility of hamstring and low back, and trunk extensor strength, flexibility and endurance slightly increased in F group compared with C group after Feldenkrais protocol even if this variation was not statistically significant. Differently, C group showed a reduction by 5% in both tests after 4 weeks. After Feldenkrais protocol, height of F group was significantly bigger than before treatment. Moreover, we found that the number of participants, who stated to have strong and frequent pain in the back and limbs, decreased during performing the Feldenkrais protocol. This effect was bigger in the cervical than lumbar spine and upper limbs.Conclusion: Our outcomes illustrate that Feldenkrais method has positive effects on muscle flexibility and supports the use of this method for dissolving muscle tensions and contractions that can cause pain in professional orchestral musicians

The Genetics of Non-Syndromic Primary Ovarian Insufficiency: A Systematic Review

Several causes for primary ovarian insufficiency (POI) have been described, including iatrogenic and environmental factor, viral infections, chronic disease as well as genetic alterations. The aim of this review was to collect all the genetic mutations associated with non-syndromic POI. All studies, including gene screening, genome-wide study and assessing genetic mutations associated with POI, were included and analyzed in this systematic review. Syndromic POI and chromosomal abnormalities were not evaluated. Single gene perturbations, including genes on the X chromosome (such as BMP15, PGRMC1 and FMR1) and genes on autosomal chromosomes (such as GDF9, FIGLA, NOBOX, ESR1, FSHR and NANOS3) have a positive correlation with non-syndromic POI. Future strategies include linkage analysis of families with multiple affected members, array comparative genomic hybridization (CGH) for analysis of copy number variations, next generation sequencing technology and genome-wide data analysis. This review showed variability of the genetic factors associated with POI. These findings may help future genetic screening studies on large cohort of women

Understanding Ovarian Hypo-Response to Exogenous Gonadotropin in Ovarian Stimulation and Its New Proposed Marker—The Follicle-To-Oocyte (FOI) Index

Hypo-responsiveness to controlled ovarian stimulation is an undervalued topic in reproductive medicine. This phenomenon manifests as a low follicles output rate (FORT) with a discrepancy between the relatively low number of pre-ovulatory follicles which develop following ovarian stimulation as compared to the number of antral follicles available at the start of stimulation. The pathophysiology mechanisms explaining the ovarian resistance to gonadotropin stimulation are not fully understood, but the fact that both hypo-responders and normal responders share similar phenotypic characteristics suggests a genotype-based mechanism. Indeed, existing evidence supports the association between specific gonadotropin and their receptor polymorphisms and ovarian hypo-response. Apart from genotypic trait, environmental contaminants and oxidative stress might also be involved in the hypo-response pathogenesis. The ratio between the number of oocytes collected at the ovum pick up and the number of antral follicles at the beginning of OS [Follicle to oocyte index (FOI)] is proposed as a novel parameter to assess the hypo-response. Compared with traditional ovarian reserve markers, FOI might reflect most optimally the dynamic nature of follicular growth in response to exogenous gonadotropin. In this review, we contextualize the role of FOI as a parameter to identify this condition, discuss the underlying mechanisms potentially implicated in the pathogenesis of hypo-response, and appraise possible the treatment strategies to overcome hyper-responsiveness to gonadotropin stimulation

Comparison of two schizophyllum commune strains in production of acetylcholinesterase inhibitors and antioxidants from submerged cultivation

In recent years, fungi have been recognized as producers of acetylcholinesterase (AChE) inhibitors, agents important for the prevention of Alzheimer’s disease (AD). This study aimed to examine the AChE inhibitory, the antioxidative and antibacterial activity of two different Schizophyllum commune strains that originated from Serbia (SRB) and Italy (IT). Submerged cultivation of grown mycelia (M) and fermentation broth (F) of ethanol (EtOH) and polysaccharide (PSH) extracts lasted for 7, 14, 21 and 28 days. For AChE activity Ellman method was performed, while for antioxidative activity, sevendifferent assays were conducted: DPPH, ABTS, FRAP, SOA, OH, NO together with total phenolic content. Antimicrobial screen, LC–MS/MS technique and FTIR measurements were performed. Different isolates exhibited different AChE activity, with PSH being the strongest (SRB, M, 28 days IC90 79.73 ± 26.34 µg/mL), while in EtOH extracts, IT stood out (F, 14 days, IC50 0.8 ± 0.6 µg/mL). PSH extracts (7 days) exhibit significant antioxidative activity (AO), opposite to EtOH extracts where 14 and 21days periods stood out. Only tw extracts showed antibacterial activity. Following LC–MS/MS analysis p-hydroxybenzoic and gallic acids were the most abundant phenolics. PSH extracts demonstrated remarkable results, making this study debut and introducing S. commune as a valuable resource of AChE inhibitors

Risk factors associated with adverse fetal outcomes in pregnancies affected by Coronavirus disease 2019 (COVID-19): a secondary analysis of the WAPM study on COVID-19.

Objectives To evaluate the strength of association between maternal and pregnancy characteristics and the risk of adverse perinatal outcomes in pregnancies with laboratory confirmed COVID-19. Methods Secondary analysis of a multinational, cohort study on all consecutive pregnant women with laboratory-confirmed COVID-19 from February 1, 2020 to April 30, 2020 from 73 centers from 22 different countries. A confirmed case of COVID-19 was defined as a positive result on real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay of nasal and pharyngeal swab specimens. The primary outcome was a composite adverse fetal outcome, defined as the presence of either abortion (pregnancy loss before 22 weeks of gestations), stillbirth (intrauterine fetal death after 22 weeks of gestation), neonatal death (death of a live-born infant within the first 28 days of life), and perinatal death (either stillbirth or neonatal death). Logistic regression analysis was performed to evaluate parameters independently associated with the primary outcome. Logistic regression was reported as odds ratio (OR) with 95% confidence interval (CI). Results Mean gestational age at diagnosis was 30.6+/-9.5 weeks, with 8.0% of women being diagnosed in the first, 22.2% in the second and 69.8% in the third trimester of pregnancy. There were six miscarriage (2.3%), six intrauterine device (IUD) (2.3) and 5 (2.0%) neonatal deaths, with an overall rate of perinatal death of 4.2% (11/265), thus resulting into 17 cases experiencing and 226 not experiencing composite adverse fetal outcome. Neither stillbirths nor neonatal deaths had congenital anomalies found at antenatal or postnatal evaluation. Furthermore, none of the cases experiencing IUD had signs of impending demise at arterial or venous Doppler. Neonatal deaths were all considered as prematurity-related adverse events. Of the 250 live-born neonates, one (0.4%) was found positive at RT-PCR pharyngeal swabs performed after delivery. The mother was tested positive during the third trimester of pregnancy. The newborn was asymptomatic and had negative RT-PCR test after 14 days of life. At logistic regression analysis, gestational age at diagnosis (OR: 0.85, 95% CI 0.8-0.9 per week increase; pPeer reviewe