The Timing Counter of the MEG experiment: calibration and performance

The MEG detector is designed to test Lepton Flavor Violation in the $\mu^+\rightarrow e^+\gamma$ decay down to a Branching Ratio of a few $10^{-13}$. The decay topology consists in the coincident emission of a monochromatic photon in direction opposite to a monochromatic positron. A precise measurement of the relative time $t_{e^+\gamma}$ is crucial to suppress the background. The Timing Counter (TC) is designed to precisely measure the time of arrival of the $e^+$ and to provide information to the trigger system. It consists of two sectors up and down stream the decay target, each consisting of two layers. The outer one made of scintillating bars and the inner one of scintillating fibers. Their design criteria and performances are described.Comment: Presented at the 12th Topical Seminar on Innovative Particle and Radiation Detectors (IPRD10) 7 - 10 June 2010, Siena. Accepted by Nuclear Physics B (Proceedings Supplements) (2011)tal

Phenomenological interpolation of the inclusive J/psi cross section to proton-proton collisions at 2.76 TeV and 5.5 TeV

We present a study of the inclusive J/psi cross section at 2.76 TeV and 5.5 TeV. The energy dependence of the cross section, rapidity and transverse momentum distributions are evaluated phenomenologically. Their knowledge is crucial as a reference for the interpretation of A-A and p-A J/psi results at the LHC. Our approach is the following: first, we estimate the energy evolution of the pt-integrated J/psi cross section at mid-rapidity; then, we evaluate the rapidity dependence; finally, we study the transverse momentum distribution trend. Whenever possible, both theory driven (based on pQCD predictions) and functional form (data driven fits) calculations are discussed. Our predictions are compared with the recently obtained results by the ALICE collaboration in pp collisions at 2.76 TeV.Comment: 23 pages, 19 figures, updated text+figures, added comparison to ALICE measurements at 2.76Te

Padrões de desempenho e produtividade animal para recria-engorda de bovinos de corte no Acre.

Introdução; Fatores de manejo da pastagem; Padrões de desempenho; Padrões de produtividade; Obtenção dos coeficientes técnicosbitstream/CPAF-AC-2010/13951/1/doc98.pd

Selecting New \u3cem\u3eBrachiaria humidicola\u3c/em\u3e Hybrids for Western Brazilian Amazon

Brachiaria humidicola is a perennial and stoloniferous forage grass, with excellent adaptation to infertile soils and waterlogging. Producers in northern Brazil have become interested in this species, especially after the degradation of large areas of lowly permeable soils sown with B. brizantha cv. Marandu, which is highly intolerant of soil waterlogging (Andrade and Valentim 2006). However, since only 3 cultivars of B. humidicola are registered in Brazil (Mapa 2013), there is a need to develop new cultivars adapted to the range of environmental conditions experienced. Recently, Embrapa Beef Cattle obtained intraspecific hybrids of B. humidicola that need to be evaluated agronomically, aiming at subsequent grazing trials and future releases. The objective of this study was to evaluate and select apomictic and sexual hybrids of B. humidicola in the environmental conditions of the state of Acre, in western Brazilian Amazon

Selecting new Brachiaria humidicola hybrids for Western Brazilian Amazon.

Brachiaria humidicola is a perennial and stoloniferous forage grass, with excellent adaptation to infertile soils and waterlogging. Producers in northern Brazil have become interested in this species, especially after the degradation of large areas of lowly permeable soils sown with B. brizantha cv. Marandu, which is highly intoler-ant of soil waterlogging (Andrade and Valentim 2006). However, since only 3 cultivars of B. humidicola are registered in Brazil (Mapa 2013), there is a need to de-velop new cultivars adapted to the range of environ-mental conditions experienced. Recently, Embrapa Beef Cattle obtained intraspecific hybrids of B. humidicola that need to be evaluated agronomically, aiming at sub-sequent grazing trials and future releases. The objective of this study was to evaluate and select apomictic and sexual hybrids of B. humidicola under the environmental conditions of the state of Acre, in western Brazilian Amazon.Publicado também nos Anais do 22º INTERNATIONAL GRASSLAND CONGRESS, Sidney, 2013

Toxicological evaluation of lactose and chitosan delivered by inhalation

These days, inhalation constitutes a promising administration route for many drugs. However, this route exhibits unique limitations, and formulations aimed at pulmonary delivery should include as few as possible additives in order to maintain lung functionality. The purpose of this work was to investigate the safety of lactose and chitosan to the pulmonary tissue when delivered by inhalation. The study was carried out with 18 Wistar rats divided in three groups receiving distilled water, lactose or chitosan. A solution of each excipient was administered by inhalation at a dose of 20 mg. The lungs were excised and processed to determine several biochemical parameters used as toxicity biomarkers. Protein and carbonyl group content, lipid peroxidation, reduced and oxidized glutathione ( GSSG), myeloperoxidase ( MPO), cooper/zinc and manganese superoxide dismutase, catalase, glutathione S-transferase and glutathione peroxidase were determined. Results of myeloperoxidase activity and glutathione disulfide lung concentrations showed a relevant decrease for chitosan group compared to control: 4.67 +/- 2.27 versus 15.10 +/- 7.27 ( P = 0.011) for MPO and 0.89 +/- 0.68 versus 2.02 +/- 0.22 ( P = 0.014) for GSSG. The other parameters did not vary significantly among groups. Lactose and chitosan administered by inhalation failed to show toxic effects to the pulmonary tissue. A protective effect against oxidative stress might even be attributed to chitosan, since some biomarkers had values significantly lower than those observed in the control group when this product was inhaled. Nevertheless, caution must be taken regarding chemical composition and technological processes applied to incorporate these products during drug formulation, in particular for dry powder inhalators

Supersymmetric Origin of Neutrino Mass

Supersymmetry with breaking of R-parity provides an attractive way to generate neutrino masses and lepton mixing angles in accordance to present neutrino data. We review the main theoretical features of the bilinear R-parity breaking (BRpV) model, and stress that it is the simplest extension of the minimal supersymmetric standard model (MSSM) which includes lepton number violation. We describe how it leads to a successful phenomenological model with hierarchical neutrino masses. In contrast to seesaw models, the BRpV model can be probed at future collider experiments, like the Large Hadron Collider or the Next Linear Collider, since the decay pattern of the lightest supersymmetric particle provides a direct connection with the lepton mixing angles determined by neutrino experiments.Comment: 21 pages, 8 figures, review for NJP focus issue on neutrino

Genetic divergence among Brachiara humidicola (Rendle) Schweick hybrids evaluated in the Western Brazilian Amazon.

The objectives of this study were to detect genetic variability among genotypes of Brachiara humidicola, study the genetic diversity and identify redundant variables in the discrimination of hybrids. Fifteen genotypes were evaluated for morphological, agronomic and nutritive characteristics in a randomized block design with six replications, in Rio Branco, Acre. Analysis of variance was performed, followed by the Scott-Knott test. Different techniques of multivariate analysis were used to study genetic diversity. Significant differences in plant performance were observed for agronomic and morphological characteristics, but not for nutritive value. There was consistency between the different clustering techniques. Four redundant characteristics were identified hat can be discarded. The existence of divergent and superior hybrids that can be used in recurrent selection (sexual) programs or can be released as new (apomictic) cultivars after testing for animal response was confirmed. The lack of genetic variability in bromatological traits indicates the need for differentiated selection strategies

Application of different DNA extraction procedures, library preparation protocols and sequencing platforms: impact on sequencing results

In this study three DNA extraction procedures, two library preparation protocols and two sequencing platforms were applied to analyse six bacterial cultures and their corresponding DNA obtained as part of a proficiency test. The impact of each variable on sequencing results was assessed using the following parameters: reads quality, assembly and alignment statistics; number of single nucleotide polymorphisms (SNPs), detected applying assembly- and alignment-based strategies; antimicrobial resistance genes (ARGs), identified on de novo assemblies of all sequenced genomes. The investigated nucleic acid extraction procedures, library preparation kits and sequencing platforms do not significantly affect de novo assembly statistics and number of SNPs and ARGs. The only exception was observed for two duplicates, which were associated to one PCR-based library preparation kit. Results from this comparative study can support researchers in the choice toward the available pre-sequencing and sequencing options, and might suggest further comparisons to be performed