The genome of the Trinidadian guppy, Poecilia reticulata, and variation in the Guanapo population

For over a century, the live bearing guppy, Poecilia reticulata, has been used to study sexual selection as well as local adaptation. Natural guppy populations differ in many traits that are of intuitively adaptive significance such as ornamentation, age at maturity, brood size and body shape. Water depth, light supply, food resources and predation regime shape these traits, and barrier waterfalls often separate contrasting environments in the same river. We have assembled and annotated the genome of an inbred single female from a high-preda- tion site in the Guanapo drainage. The final assembly comprises 731.6 Mb with a scaffold N50 of 5.3 MB. Scaffolds were mapped to linkage groups, placing 95% of the genome assembly on the 22 autosomes and the X-chromosome. To investigate genetic variation in the population used for the genome assembly, we sequenced 10 wild caught male individu- als. The identified 5 million SNPs correspond to an average nucleotide diversity (π) of 0.0025. The genome assembly and SNP map provide a rich resource for investigating adap- tation to different predation regimes. In addition, comparisons with the genomes of other Poeciliid species, which differ greatly in mechanisms of sex determination and maternal resource allocation, as well as comparisons to other teleost genera can begin to reveal how live bearing evolved in teleost fish

Black Holes in Higher Dimensions

We review black hole solutions of higher-dimensional vacuum gravity, and of higher-dimensional supergravity theories. The discussion of vacuum gravity is pedagogical, with detailed reviews of Myers-Perry solutions, black rings, and solution-generating techniques. We discuss black hole solutions of maximal supergravity theories, including black holes in anti-de Sitter space. General results and open problems are discussed throughout.Comment: 76 pages, 14 figures; review article for Living Reviews in Relativity. v2: some improvements and refs adde

Winnicott, Donald

Winnicott was a British psychoanalyst famous for identifying an area of experiencing between inner psychic life and social reality called the potential space. In his work, potentiality is what can emerge on the basis of what is already there, or, in other words, it is there, where new possibilities can emerge. The idea of potentiality – and a practical concern with the possibility of possibility – can be found at the heart of all aspects of his work. First, as a researcher, he pragmatically expanded the psychoanalytical tradition on the basis of his unique clinical experience. Second, as a theoretician, he developed an understanding of human development whereby the child emerges as a person within a good-enough environment, and, in a first phase, differentiates from the carer thanks to a complex and paradoxical process of self-formation through symbol use. These observations led him to propose the ideas of transitional phenomena or potential space. What might be called “potential phenomena” (or phenomena of potentialization) mark the beginning of symbolism in the play between infant and carer and evolve via more elaborate child’s play into the cultural experiencing and creativity that can continue throughout adulthood. Third, in his clinical work, Winnicott considered psychotherapy as a technique for creating a potential space to engage in a form of shared play. For children or adults who lacked the possibility to play, these therapeutic spaces aimed to provide a good enough environment –institutional, relational – within which the person can come to experience phenomena of potentialization which render the possible, possible