177 research outputs found
Features of the course and effectiveness of treatment of tuberculosis in pregnant women with different HIV status
The study presents the results of comparing the social status and the efficiency of TB treatment in pregnant women with or without HIV treated in Krasnoyarsk Regional TB Clinic β 1 in the years 2010β2014. It is based on a retrospective analysis of health cards of 133 pregnant TB patients divided into groups: Group 1 (TB), n=109; Group 2 (TB and HIV), n=24. More than a half of the women (51,3% and 54,1% accordingly) were new TB patients, the others had been previously treated for TB. A moderate immunodeficiency was more often detected in co-infected pregnant women (mean CD4+ lymphocyte count being 387 cells/ml), although in 4 patients the CD4 count was lower than 200 cells/ml. The registered rates of bacterioexcretion and lung disintegration were practically the same (57,7% and 58,3% versus 53,2% and 54,1% accordingly); MDR TB was diagnosed in 51,1% in Group 1 and in 60,0% in Group 2.Results: Patients of both groups had various social problems. However, the most aggravating medico-social factor among the co-infected women was active drug abuse during pregnancy (proved in 37,5%). The clinical course of TB in patients with HIV was severer, they more often developed acute forms of the disease. Preterm delivery was more frequent in TB/HIV cases (46,1% vs. 12,3%, p<0,01). Children born by the women with HIV co-infection showed signs of prematurity and intrauterine growth retardation more often than those born by HIV-negative patients (50,0% vs. 12,3%, p<0,01). Treatment efficiency for TB was authentically less in co-infected cases (33,4% vs. 58,7%, p<0,01). TB recurrence was more often registered in HIV-positive patients (25,0% vs. 3,1%, p<0,01). As for chemotherapy tolerance, treatment adherence or lethality rate, no authentic differences between the groups have been revealed
THE CHARACTERISTICS OF MORTALITY OF THE POPULATION OF IRKUTSK FROM EXTERNAL REASONS AND SOME DISEASES RELATED ETHYL ALCOHOL CONSUMPTION
To our mind, the population alcoholization is the one of the major medical-social problems in Irkutsk region. According to official statistics it is established that in recent years the average index of incidence with diagnosis of an alcoholism and alcoholic psychosis established for the first time as a whole was higher in Irkutsk region, than in the Russian Federation and Siberian Federal district -1,7 and 1,5 times respectively. Sociological polls of the population of Irkutsk showed that 10 % of adult population and less than 20 % of youth do not take alcoholic drinks only. Abuse of alcohol makes a particular contribution to increase in number of lethal cases from diseases of system of blood circulation and the external reasons (mechanical trauma, suicides). It is not possible to estimate these indexes according to statistical data. The purpose of the real research was studying of a share of deadly outcomes among the population of Irkutsk, associated with ethyl alcohol. The profound personified analysis of mortality of the population of Irkutsk from the external reasons and some diseases (according to the international classification of diseases of the 10th revision) was carried out according to archive of Irkutsk regional bureau of a forensic medical expertise during 2000-2012, in cases when ethyl alcohol was found in cadaver blood. It was established, that the share of acute poisonings with ethyl alcohol makes about 4 % in structure of common mortality of the population of Irkutsk. The share of persons of young age of the dead as a result of an acute alcoholic poisoning makes nearly 20 % in recentyears. The high level of suicide activity of the population of the city interfaced to alcohol intake was revealed. More than 50 % were in an alcohol intoxication of various degree, among the persons prematurely left life. The share of the lethal mechanical traumas, associated with alcohol intoxication, made about a half from all cases of a mechanical trauma. During the 13-year period the decrease of the share of death resulted from cardiovascular diseases, associated with ethyl alcohol, was observed (with 30 to 16 %). Thus among the persons of young age having diseases of cardiovascular system, more than 50 % were at the time of death approach in an alcohol intoxication. The conducted research shows that the actual"hidden" losses of the population interfaced to alcohol intake, are much higher. The alcoholization of the population influences not only formation of losses from acute alcoholic poisonings, but also from the external reasons and diseases against which there was an abuse of ethyl alcohol
Recombinant Pseudomonas Vaccine: Technological Aspects of Obtaining and Evaluating Quality Indicators
For an aim to prevent Pseudomonas aeruginosa, a candidate recombinant vaccine has been developed. This vaccine β (RPV) was based on two protective proteins of P. aeruginosa: the outer membrane protein F (OprF) and the recombinant truncated form of the Exotoxin A (toxoid) that were adsorbed on the aluminum hydroxide. The optimal immunization schedule for mice included two intraperitoneal administrations with a two-week interval. RPV promoted to increase survival rates in challenged immunized mice and stimulated humoral and innate immune responses. During preclinical studies, we confirmed the immunogenicity of the vaccine that had not pyrogenicity, acute and chronic toxicity, allergenicity and immunotoxicity.
Keywords: Pseudomonas aeruginosa, outer membrane protein F (OprF), toxoid, Pseudomonas Recombinant Vaccine (PRV
The model of monitoring of vocational pedagogical competences of professors in secondary vocational education
The relevance of the researched issue is preconditioned by the strategic changes in the secondary vocational education system taking place not only in Russia, but also in majority of industrially developed countries. Provision of the system with qualified pedagogical staff is the leading strategic objective of development of the secondary vocational educational system. Its solution must be based on the justified monitoring system, which objectively represents the condition as well as quantitative and qualitative changes taking place in the educational sphere. The article is aimed at developing, substantiating and approbating the model of monitoring of vocational pedagogical competences of professors in secondary vocational education. Integration of the competence, functional and general pedagogical analysis became the leading approach to research into this problem, which has enabled substantiating the model of monitoring of vocational pedagogical competences of professors in the secondary vocational education system. The article presents results of the theoretical and methodological analysis of Russian and foreign research dedicated to identification of key and emerging competences in various spheres. The competence model of a professor of secondary vocational education has been developed and substantiated as a monitoring basis. The article may be useful to improve the quality of the human resource potential in the secondary vocational education system in Russia, to define current and long-range objectives of its development. Β© 2016 Andryukhina et al
Vocational pedagogical competencies of a professor in the secondary vocational education system: Approbation of monitoring model
The relevance of the researched issue is preconditioned by the strategic changes in the secondary vocational education system taking place not only in Russia, but also in majority of industrially developed countries. Provision of the system with qualified pedagogical staff is the leading strategic objective of development of the secondary vocational educational system. Its solution must be based on the justified monitoring system, which objectively represents the condition as well as quantitative and qualitative changes taking place in the educational sphere. The article is aimed at approbating the model of monitoring of vocational pedagogical competences of professors in secondary vocational education. Integration of the competence, functional and general pedagogical analysis became the leading approach to research into this problem, which has enabled substantiating the model of monitoring of vocational pedagogical competences of professors in the secondary vocational education system. The competence model of a professor of secondary vocational education has been developed and substantiated as a monitoring basis. Results of model approbation and monitoring tools have been presented. The article may be useful to improve the quality of the human resource potential in the secondary vocational education system in Russia, to define current and long-range objectives of its development. Β© 2016 Andryukhina et al
CLINICAL COURSE OF HIV-ASSOCIATED TUBERCULOSIS IN THE PREGNANT WOMAN AND NEWBORN
The article describes the clinical case of TB/HIV coinfection in the pregnant woman and newborn. The discussion of the management tactics included main issues on which treatment success depended on: the right choice of chemotherapy regimen, correct decision on the time of delivery due to life-threatening conditions of the mother, timely diagnostics of tuberculosis in the newborn. It is necessary to develop cross-disciplinary guidelines by professional medical communities on the management of pregnant women with TB/HIV coinfection which will allow enhancing the quality of medical care to pregnant women and newborns at all stages of follow-up
ΠΠ½Π΅Π±ΠΎΠ»ΡΠ½ΠΈΡΠ½ΡΠ΅ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠΈ Ρ Π²Π·ΡΠΎΡΠ»ΡΡ Π±ΠΎΠ»ΡΠ½ΡΡ ΠΠΠ§-ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ: ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΡΠ΅ΡΠ΅Π½ΠΈΡ ΠΈ Π»Π΅ΡΠ΅Π½ΠΈΡ, ΠΏΡΠΎΡΠΈΠ»Π°ΠΊΡΠΈΠΊΠ°
This is a review of published data on community-acquired pneumonia (CAP) in adult HIV-infected patients. Morbidity of bacterial pneumonia in HIV-infected patients is 5- to 10-fold higher than that in general population. Wide use of antiretroviral therapy (ARVT) is associated with a reduction in morbidity of CAP in HIV-infected patients, but this reduction is not as significant as for other opportunistic infections. The most important risk factors for CAP are drug abuse, tobacco smoking, HIV-associated immunosuppression, hepatic cirrhosis, not to be treated with ARVT or ARVT withdrawal. Severe, complicated and invasive course of CAP and poor outcomes are seen more often in HIV-infected patients compared to general population. Bacterial pneumonia should be differed from pneumonia caused by Pneumocystis and from tuberculosis, especially in endemic countries and in patients with insidious onset of the disease. The standard therapy of CAP is applied in all patients independently of HIV status. However, administration of fluoroquinolones is restricted in regions with high prevalence of multi-drug resistant tuberculosis in HIV-infected patients before tuberculosis is excluded. Several studies have demonstrated that, in case of false initial diagnosis, 10-day monotherapy with a fluoroquinolone could form the resistance of Mycobacteria tuberculosis against this drug; this significantly complicates further treatment of tuberculosis and increases the treatment cost. Beta-lactams are not effective against tuberculosis; in 2016, WHO excluded macrolides from the list of medications for therapy of tuberculosis due to their low activity against M. tuberculosis. Therefore, empirical therapy of CAP in HIV-infected patients should be started with combination of beta-lactam antibiotic and newer macrolide. A strong protective effect of PPV23 vaccine against CAP was confirmed in HIV-infected patients, but the highest protective efficacy was seen in patients with relatively preserved immunity compared to patients with CD4 < 200 cells Γ Β΅L-1.ΠΠΎ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ°ΠΌ Π°Π½Π°Π»ΠΈΠ·Π° ΠΏΡΠ±Π»ΠΈΠΊΠ°ΡΠΈΠΉ ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π΅ΠΌΠΎΡΡΡ Π±Π°ΠΊΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠ΅ΠΉ Ρ ΠΈΠ½ΡΠΈΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
Π²ΠΈΡΡΡΠΎΠΌ ΠΈΠΌΠΌΡΠ½ΠΎΠ΄Π΅ΡΠΈΡΠΈΡΠ° ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ° (ΠΠΠ§) Π² 5β10 ΡΠ°Π· ΠΏΡΠ΅Π²ΡΡΠ°Π΅Ρ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Ρ Π² ΠΏΠΎΠΏΡΠ»ΡΡΠΈΠΈ. ΠΡΠΈ ΡΠΈΡΠΎΠΊΠΎΠΌΠ°ΡΡΡΠ°Π±Π½ΠΎΠΌ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠΈ Π°Π½ΡΠΈΡΠ΅ΡΡΠΎΠ²ΠΈΡΡΡΠ½ΠΎΠΉΒ ΡΠ΅ΡΠ°ΠΏΠΈΠΈΒ (ΠΠ ΠΠ’) Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π΅ΠΌΠΎΡΡΡ Π²Π½Π΅Π³ΠΎΡΠΏΠΈΡΠ°Π»ΡΠ½ΠΎΠΉ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠ΅ΠΉ (ΠΠ) ΡΠ½ΠΈΠΆΠ°Π΅ΡΡΡ, Π½ΠΎ Π½Π΅ ΡΠ°ΠΊ Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΠΎ, ΠΊΠ°ΠΊ Π² ΡΠ»ΡΡΠ°Π΅ Π΄ΡΡΠ³ΠΈΡ
ΠΎΠΏΠΏΠΎΡΡΡΠ½ΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΉ. ΠΠ°ΠΈΠ±ΠΎΠ»Π΅Π΅ Π·Π½Π°ΡΠΈΠΌΡΠΌΠΈ ΡΠ°ΠΊΡΠΎΡΠ°ΠΌΠΈ ΡΠΈΡΠΊΠ° ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΠ ΠΏΡΠΈΠ·Π½Π°Π½Ρ ΠΏΠΎΡΡΠ΅Π±Π»Π΅Π½ΠΈΠ΅ Π½Π°ΡΠΊΠΎΡΠΈΠΊΠΎΠ², ΡΠ°Π±Π°ΠΊΠΎΠΊΡΡΠ΅Π½ΠΈΠ΅, ΠΠΠ§-Π°ΡΡΠΎΡΠΈΠΈΡΠΎΠ²Π°Π½Π½Π°Ρ ΠΈΠΌΠΌΡΠ½ΠΎΡΡΠΏΡΠ΅ΡΡΠΈΡ, ΡΠΈΡΡΠΎΠ· ΠΏΠ΅ΡΠ΅Π½ΠΈ ΠΈ ΠΎΡΡΡΡΡΡΠ²ΠΈΠ΅ ΠΠ ΠΠ’ ΠΈΠ»ΠΈ ΠΏΠ΅ΡΠ΅ΡΡΠ²Ρ Π² Π»Π΅ΡΠ΅Π½ΠΈΠΈ. Π Π°Π·Π²ΠΈΡΠΈΠ΅ ΡΡΠΆΠ΅Π»ΡΡ
, ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½Π½ΡΡ
ΠΈ ΠΈΠ½Π²Π°Π·ΠΈΠ²Π½ΡΡ
ΡΠΎΡΠΌ ΠΠ ΠΈ, ΠΊΠ°ΠΊ ΡΠ»Π΅Π΄ΡΡΠ²ΠΈΠ΅, ΡΠΈΡΠΊ Π½Π΅Π±Π»Π°Π³ΠΎΠΏΡΠΈΡΡΠ½ΠΎΠ³ΠΎ ΠΈΡΡ
ΠΎΠ΄Π° Ρ Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΠΠ§-ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ Π²ΡΡΡΠ΅ΡΠ°Π΅ΡΡΡ Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΠΎ ΡΠ°ΡΠ΅, ΡΠ΅ΠΌ ΡΡΠ΅Π΄ΠΈ Π½Π°ΡΠ΅Π»Π΅Π½ΠΈΡ Π² ΡΠ΅Π»ΠΎΠΌ. Π ΡΠ½Π΄Π΅ΠΌΠΈΡΠ½ΡΡ
ΠΏΠΎ ΡΡΠ±Π΅ΡΠΊΡΠ»Π΅Π·Ρ ΡΡΡΠ°Π½Π°Ρ
Ρ Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΠΠ§-ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ Π±Π°ΠΊΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΡΡ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΡ Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ ΡΠ°ΡΡΠΎ ΠΏΡΠΈΡ
ΠΎΠ΄ΠΈΡΡΡ Π΄ΠΈΡΡΠ΅ΡΠ΅Π½ΡΠΈΡΠΎΠ²Π°ΡΡ Ρ ΠΏΠ½Π΅Π²ΠΌΠΎΡΠΈΡΡΠ½ΠΎΠΉ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠ΅ΠΉ ΠΈ ΡΡΠ±Π΅ΡΠΊΡΠ»Π΅Π·ΠΎΠΌ, ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎ Ρ Π»ΠΈΡ Ρ ΠΏΠΎΠ΄ΠΎΡΡΡΡΠΌ Π½Π°ΡΠ°Π»ΠΎΠΌ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ. ΠΠ°Π·ΠΎΠ²ΡΠ΅ ΠΏΡΠΈΠ½ΡΠΈΠΏΡ Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΠ ΠΎΠ΄ΠΈΠ½Π°ΠΊΠΎΠ²Ρ Π΄Π»Ρ Π²ΡΠ΅Ρ
ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Π²Π½Π΅ Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΠΈ ΠΎΡ ΠΠΠ§-ΡΡΠ°ΡΡΡΠ°. ΠΠ΄Π½Π°ΠΊΠΎ Π² ΡΠ΅Π³ΠΈΠΎΠ½Π°Ρ
Ρ Π²ΡΡΠΎΠΊΠΈΠΌ Π±ΡΠ΅ΠΌΠ΅Π½Π΅ΠΌ ΡΡΠ±Π΅ΡΠΊΡΠ»Π΅Π·Π° Ρ ΠΌΠ½ΠΎΠΆΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠΉ Π»Π΅ΠΊΠ°ΡΡΡΠ²Π΅Π½Π½ΠΎΠΉ ΡΡΡΠΎΠΉΡΠΈΠ²ΠΎΡΡΡΡ ΠΌΠΈΠΊΠΎΠ±Π°ΠΊΡΠ΅ΡΠΈΠΉ ΡΡΠ±Π΅ΡΠΊΡΠ»Π΅Π·Π° (ΠΠΠ’) Π½Π°Π·Π½Π°ΡΠ΅Π½ΠΈΠ΅ ΡΡΠΎΡΡ
ΠΈΠ½ΠΎΠ»ΠΎΠ½Π° ΠΠΠ§-ΠΈΠ½ΡΠΈΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΌΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΡ Ρ Π½Π΅ΠΈΡΠΊΠ»ΡΡΠ΅Π½Π½ΡΠΌ ΡΡΠ±Π΅ΡΠΊΡΠ»Π΅Π·ΠΎΠΌ ΠΈΠΌΠ΅Π΅Ρ ΡΠ΅ΡΡΠ΅Π·Π½ΡΠ΅ ΠΎΠ³ΡΠ°Π½ΠΈΡΠ΅Π½ΠΈΡ. ΠΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ Π² ΡΠ»ΡΡΠ°Π΅ ΠΎΡΠΈΠ±ΠΎΡΠ½ΠΎΠ³ΠΎ ΠΏΠ΅ΡΠ²ΠΎΠ½Π°ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ Π΄ΠΈΠ°Π³Π½ΠΎΠ·Π° Π·Π° 10 Π΄Π½Π΅ΠΉ ΠΌΠΎΠ½ΠΎΡΠ΅ΡΠ°ΠΏΠΈΠΈ ΡΡΠΎΡΡ
ΠΈΠ½ΠΎΠ»ΠΎΠ½ΠΎΠΌ ΠΠΠ’ ΡΠΎΡΠΌΠΈΡΡΡΡ ΡΡΡΠΎΠΉΡΠΈΠ²ΠΎΡΡΡ ΠΊ ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΡ, ΡΡΠΎ Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΠΎ ΡΡΠ»ΠΎΠΆΠ½ΡΠ΅Ρ ΠΈ Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΠΎ ΠΏΠΎΠ²ΡΡΠ°Π΅Ρ ΡΡΠΎΠΈΠΌΠΎΡΡΡ Π»Π΅ΡΠ΅Π½ΠΈΡ ΡΡΠ±Π΅ΡΠΊΡΠ»Π΅Π·Π°. Ξ²-ΠΠ°ΠΊΡΠ°ΠΌΠ½ΡΠ΅ Π°Π½ΡΠΈΠ±Π°ΠΊΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΡΠ΅ ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΡ (ΠΠΠ) Π½Π΅ ΠΎΠ±Π»Π°Π΄Π°ΡΡ ΠΏΡΠΎΡΠΈΠ²ΠΎΡΡΠ±Π΅ΡΠΊΡΠ»Π΅Π·Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡΡ, Π° ΠΌΠ°ΠΊΡΠΎΠ»ΠΈΠ΄Ρ ΠΏΠΎ ΠΏΡΠΈΡΠΈΠ½Π΅ ΡΡΠ΅Π·Π²ΡΡΠ°ΠΉΠ½ΠΎ ΡΠ»Π°Π±ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π² ΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠΈ ΠΠΠ’ ΠΡΠ΅ΠΌΠΈΡΠ½ΠΎΠΉ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠ΅ΠΉ Π·Π΄ΡΠ°Π²ΠΎΠΎΡ
ΡΠ°Π½Π΅Π½ΠΈΡ Π² 2016 Π³. ΠΈΡΠΊΠ»ΡΡΠ΅Π½Ρ ΠΈΠ· ΡΠΏΠΈΡΠΊΠ° ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠΎΠ² Π΄Π»Ρ Π»Π΅ΡΠ΅Π½ΠΈΡ ΡΡΠ±Π΅ΡΠΊΡΠ»Π΅Π·Π°. ΠΠΎΡΡΠΎΠΌΡ Ρ ΠΠΠ§-ΠΈΠ½ΡΠΈΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ ΠΎΠΏΡΠ°Π²Π΄Π°Π½Π½ΡΠΌ Π½Π°ΡΠ°Π»ΠΎΠΌ ΡΡΠ°ΡΡΠΎΠ²ΠΎΠΉ ΡΠΌΠΏΠΈΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΠ΅ΡΠ°ΠΏΠΈΠΈ ΠΠ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΈΠΌΠ΅Π½Π½ΠΎ ΠΊΠΎΠΌΠ±ΠΈΠ½Π°ΡΠΈΡ Ξ²-Π»Π°ΠΊΡΠ°ΠΌΠ½ΠΎΠ³ΠΎ ΠΠΠ ΠΈ ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠ³ΠΎ ΠΌΠ°ΠΊΡΠΎΠ»ΠΈΠ΄Π°. ΠΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ Π²Π°ΠΊΡΠΈΠ½Π°ΡΠΈΡ 23-Π²Π°Π»Π΅Π½ΡΠ½ΠΎΠΉ ΠΏΠΎΠ»ΠΈΡΠ°Ρ
Π°ΡΠΈΠ΄Π½ΠΎΠΉ ΠΏΠ½Π΅Π²ΠΌΠΎΠΊΠΎΠΊΠΊΠΎΠ²ΠΎΠΉ Π²Π°ΠΊΡΠΈΠ½ΠΎΠΉ ΠΈΠΌΠ΅Π΅Ρ ΡΠ΅ΡΡΠ΅Π·Π½ΠΎΠ΅ ΠΏΡΠΎΠ΅ΠΊΡΠΈΠ²Π½ΠΎΠ΅ Π΄Π΅ΠΉΡΡΠ²ΠΈΠ΅ Π² ΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠΈ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΠ Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ ΠΠΠ§-ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ, ΠΎΠ΄Π½Π°ΠΊΠΎ Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ Π²ΡΡΠΎΠΊΠΈΠΉ ΠΈΠ½Π΄Π΅ΠΊΡ ΠΏΡΠΎΡΠΈΠ»Π°ΠΊΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΎΡΠΌΠ΅ΡΠ΅Π½ Ρ Π»ΠΈΡ Ρ ΠΎΡΠ½ΠΎΡΠΈΡΠ΅Π»ΡΠ½ΠΎ ΡΠΎΡ
ΡΠ°Π½Π½ΡΠΌ ΠΈΠΌΠΌΡΠ½ΠΈΡΠ΅ΡΠΎΠΌ, Π½Π΅ΠΆΠ΅Π»ΠΈ Ρ Π±ΠΎΠ»ΡΠ½ΡΡ
Ρ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎΠΌ CD4 < 200 ΠΊΠ»Π΅ΡΠΎΠΊ / ΠΌΠΊΠ»
ΠΠ‘ΠΠΠΠΠΠΠ‘Π’Π Π’ΠΠ§ΠΠΠΠ― Π ΠΠ€Π€ΠΠΠ’ΠΠΠΠΠ‘Π’Π¬ ΠΠΠ§ΠΠΠΠ― Π’Π£ΠΠΠ ΠΠ£ΠΠΠΠ Π£ ΠΠΠ ΠΠΠΠΠΠ«Π₯ Π‘ Π ΠΠΠΠΠ§ΠΠ«Π ΠΠΠ§-Π‘Π’ΠΠ’Π£Π‘ΠΠ
The study presents the results of comparing the social status and the efficiency of TB treatment in pregnant women with or without HIV treated in Krasnoyarsk Regional TB Clinic β 1 in the years 2010β2014. It is based on a retrospective analysis of health cards of 133 pregnant TB patients divided into groups: Group 1 (TB), n=109; Group 2 (TB and HIV), n=24. More than a half of the women (51,3% and 54,1% accordingly) were new TB patients, the others had been previously treated for TB. A moderate immunodeficiency was more often detected in co-infected pregnant women (mean CD4+ lymphocyte count being 387 cells/ml), although in 4 patients the CD4 count was lower than 200 cells/ml. The registered rates of bacterioexcretion and lung disintegration were practically the same (57,7% and 58,3% versus 53,2% and 54,1% accordingly); MDR TB was diagnosed in 51,1% in Group 1 and in 60,0% in Group 2.Results: Patients of both groups had various social problems. However, the most aggravating medico-social factor among the co-infected women was active drug abuse during pregnancy (proved in 37,5%). The clinical course of TB in patients with HIV was severer, they more often developed acute forms of the disease. Preterm delivery was more frequent in TB/HIV cases (46,1% vs. 12,3%, p<0,01). Children born by the women with HIV co-infection showed signs of prematurity and intrauterine growth retardation more often than those born by HIV-negative patients (50,0% vs. 12,3%, p<0,01). Treatment efficiency for TB was authentically less in co-infected cases (33,4% vs. 58,7%, p<0,01). TB recurrence was more often registered in HIV-positive patients (25,0% vs. 3,1%, p<0,01). As for chemotherapy tolerance, treatment adherence or lethality rate, no authentic differences between the groups have been revealed.Β ΠΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Ρ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ ΡΠΎΡΠΈΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ°ΡΡΡΠ° ΠΈ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π»Π΅ΡΠ΅Π½ΠΈΡ ΡΡΠ±Π΅ΡΠΊΡΠ»Π΅Π·Π° Ρ Π±Π΅ΡΠ΅ΠΌΠ΅Π½Π½ΡΡ
Π² Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΠΈ ΠΎΡ ΠΠΠ§-ΡΡΠ°ΡΡΡΠ°, Π½Π°Ρ
ΠΎΠ΄ΠΈΠ²ΡΠΈΡ
ΡΡ ΠΏΠΎΠ΄ Π½Π°Π±Π»ΡΠ΄Π΅Π½ΠΈΠ΅ΠΌ Π² ΠΡΠ°ΡΠ½ΠΎΡΡΡΠΊΠΎΠΌ ΠΊΡΠ°Π΅Π²ΠΎΠΌ ΠΏΡΠΎΡΠΈΠ²ΠΎΡΡΠ±Π΅ΡΠΊΡΠ»Π΅Π·Π½ΠΎΠΌ Π΄ΠΈΡΠΏΠ°Π½ΡΠ΅ΡΠ΅ Π² ΠΏΠ΅ΡΠΈΠΎΠ΄ Ρ 2010 ΠΏΠΎ 2014 Π³. ΠΡΠΎΠ²Π΅Π΄Π΅Π½ ΡΠ΅ΡΡΠΎΡΠΏΠ΅ΠΊΡΠΈΠ²Π½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΈΡ
Π΄ΠΎΠΊΡΠΌΠ΅Π½ΡΠΎΠ² 133 Π±Π΅ΡΠ΅ΠΌΠ΅Π½Π½ΡΡ
, Π±ΠΎΠ»ΡΠ½ΡΡ
ΡΡΠ±Π΅ΡΠΊΡΠ»Π΅Π·ΠΎΠΌ: 1 Π³ΡΡΠΏΠΏΠ° (Π’Π) n= 109; 2 Π³ΡΡΠΏΠΏΠ° (ΠΠΠ§-ΠΈ/Π’Π) n=24. ΠΠ΅ΡΠ΅Π½ΠΈΠ΅ ΠΏΠΎ ΠΏΠΎΠ²ΠΎΠ΄Ρ Π²ΠΏΠ΅ΡΠ²ΡΠ΅ Π²ΡΡΠ²Π»Π΅Π½Π½ΠΎΠ³ΠΎ ΡΡΠ±Π΅ΡΠΊΡΠ»Π΅Π·Π° ΠΏΠΎΠ»ΡΡΠ°Π»ΠΈ Π±ΠΎΠ»Π΅Π΅ ΠΏΠΎΠ»ΠΎΠ²ΠΈΠ½Ρ ΠΆΠ΅Π½ΡΠΈΠ½ ΠΎΠ±Π΅ΠΈΡ
Π³ΡΡΠΏΠΏ (51,3% ΠΈ 54,1%), ΠΎΡΡΠ°Π»ΡΠ½ΡΠ΅ Π±ΡΠ»ΠΈ ΡΠ°Π½Π΅Π΅ Π»Π΅ΡΠ΅Π½Π½ΡΠ΅. Π£ Π±Π΅ΡΠ΅ΠΌΠ΅Π½Π½ΡΡ
Ρ ΠΊΠΎΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ ΡΠ°ΡΠ΅ ΡΠ΅Π³ΠΈΡΡΡΠΈΡΠΎΠ²Π°Π»ΠΈ ΡΠΌΠ΅ΡΠ΅Π½Π½ΡΠΉ ΠΈΠΌΠΌΡΠ½ΠΎΠ΄Π΅ΡΠΈΡΠΈΡ (ΠΌΠ΅Π΄ΠΈΠ°Π½Π° CD4+Π»ΠΈΠΌΡΠΎΡΠΈΡΠΎΠ² β 387 ΠΊΠ»Π΅ΡΠΎΠΊ/ΠΌΠΊΠ»), ΠΎΠ΄Π½Π°ΠΊΠΎ Ρ 4 ΠΆΠ΅Π½ΡΠΈΠ½ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ CD4 ΠΊΠ»Π΅ΡΠΎΠΊ Π½Π΅ ΠΏΡΠ΅Π²ΡΡΠ°Π»ΠΎ 200. ΠΠ°ΠΊΡΠ΅ΡΠΈΠΎΠ²ΡΠ΄Π΅Π»Π΅Π½ΠΈΠ΅ ΠΈΠ· ΠΌΠΎΠΊΡΠΎΡΡ ΠΈ ΡΠ°ΡΠΏΠ°Π΄ Π»Π΅Π³ΠΎΡΠ½ΠΎΠΉ ΡΠΊΠ°Π½ΠΈ Π²ΡΡΠ²Π»ΡΠ»ΠΈ ΠΏΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠΈ Ρ ΠΎΠ΄ΠΈΠ½Π°ΠΊΠΎΠ²ΠΎΠΉ ΡΠ°ΡΡΠΎΡΠΎΠΉ (Π² 57,7 ΠΈ 58,3%; 53,2 ΠΈ 54,1% ΡΠ»ΡΡΠ°Π΅Π² ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²Π΅Π½Π½ΠΎ), ΠΠΠ£ ΠΠΠ’ ΡΠ΅Π³ΠΈΡΡΡΠΈΡΠΎΠ²Π°Π»ΠΈ Π² 51,1% ΠΈ 60,0% ΡΠ»ΡΡΠ°Π΅Π² ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²Π΅Π½Π½ΠΎ.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ: ΡΠΎΡΠΈΠ°Π»ΡΠ½ΠΎΠ΅ Π½Π΅Π±Π»Π°Π³ΠΎΠΏΠΎΠ»ΡΡΠΈΠ΅ Π΄Π΅ΠΌΠΎΠ½ΡΡΡΠΈΡΠΎΠ²Π°Π»ΠΈ Π±ΠΎΠ»ΡΠ½ΡΠ΅ ΠΎΠ±Π΅ΠΈΡ
Π³ΡΡΠΏΠΏ, ΠΎΠ΄Π½Π°ΠΊΠΎ Ρ ΠΆΠ΅Π½ΡΠΈΠ½ Ρ ΠΊΠΎΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ Π² ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ ΠΎΡΡΠ³ΠΎΡΠ°ΡΡΠ΅Π³ΠΎ ΠΌΠ΅Π΄ΠΈ- ΠΊΠΎ-ΡΠΎΡΠΈΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ°ΠΊΡΠΎΡΠ° ΠΎΡΠΌΠ΅ΡΠ΅Π½ΠΎ Π°ΠΊΡΠΈΠ²Π½ΠΎΠ΅ Π½Π°ΡΠΊΠΎΠΏΠΎΡΡΠ΅Π±Π»Π΅Π½ΠΈΠ΅ Π² ΠΏΠ΅ΡΠΈΠΎΠ΄ Π±Π΅ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΡΡΠΈ (Ρ 37,5%). ΠΡΡΠ²Π»Π΅Π½ΠΎ, ΡΡΠΎ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΡΠ΅ΡΠ΅Π½ΠΈΠ΅ ΡΡΠ±Π΅ΡΠΊΡΠ»Π΅Π·Π½ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠ° Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠΊ Ρ ΠΠΠ§-ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ Π±ΡΠ»ΠΎ Π±ΠΎΠ»Π΅Π΅ ΡΡΠΆΠ΅Π»ΠΎΠ΅, ΡΠ°ΡΠ΅ ΡΠ΅Π³ΠΈΡΡΡΠΈΡΠΎΠ²Π°Π»ΠΈΡΡ ΠΎΡΡΡΠΎΠΏΡΠΎΠ³ΡΠ΅ΡΡΠΈΡΡΡΡΠΈΠ΅ ΡΠΎΡΠΌΡ. ΠΡΠ΅ΠΆΠ΄Π΅Π²ΡΠ΅ΠΌΠ΅Π½Π½ΡΠ΅ ΡΠΎΠ΄Ρ ΡΠ°ΡΠ΅ ΡΠ»ΡΡΠ°Π»ΠΈΡΡ Ρ ΠΆΠ΅Π½ΡΠΈΠ½ Ρ ΠΠΠ§-ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ (46,1% ΠΏΡΠΎΡΠΈΠ² 12,3%, p<0,01). ΠΠ΅ΡΠΈ, ΡΠΎΠΆΠ΄Π΅Π½Π½ΡΠ΅ ΠΎΡ ΠΌΠ°ΡΠ΅ΡΠ΅ΠΉ Ρ ΠΊΠΎΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ (ΠΠΠ§-ΠΈ/Π’Π), ΡΠ°ΡΠ΅ ΠΈΠΌΠ΅Π»ΠΈ ΠΏΡΠΈΠ·Π½Π°ΠΊΠΈ Π½Π΅Π΄ΠΎΠ½ΠΎΡΠ΅Π½Π½ΠΎΡΡΠΈ ΠΈ ΠΠΠ£Π , ΡΠ΅ΠΌ ΠΌΠ»Π°Π΄Π΅Π½ΡΡ ΠΎΡ ΠΌΠ°ΡΠ΅ΡΠ΅ΠΉ Π±Π΅Π· ΠΠΠ§-ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΈ (50,0% ΠΏΡΠΎΡΠΈΠ² 12,3%, p<0,01). ΠΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΊΡΡΡΠ° Π»Π΅ΡΠ΅Π½ΠΈΡ ΡΡΠ±Π΅ΡΠΊΡΠ»Π΅Π·Π° Π±ΡΠ»Π° Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΠΎ Π½ΠΈΠΆΠ΅ Ρ Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΊΠΎΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ (33,4% ΠΏΡΠΎΡΠΈΠ² 58,7%, p<0,01). Π Π΅ΡΠΈΠ΄ΠΈΠ² ΡΡΠ±Π΅ΡΠΊΡΠ»Π΅Π·Π° ΡΠ°ΡΠ΅ ΡΠ΅Π³ΠΈΡΡΡΠΈΡΠΎΠ²Π°Π»ΠΈ ΡΡΠ΅Π΄ΠΈ ΠΆΠ΅Π½ΡΠΈΠ½ Ρ ΠΠΠ§-ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ (25,0% ΠΏΡΠΎΡΠΈΠ² 3,1%, p<0,01). ΠΠΎ ΠΏΠ΅ΡΠ΅Π½ΠΎΡΠΈΠΌΠΎΡΡΠΈ Ρ
ΠΈΠΌΠΈΠΎΡΠ΅ΡΠ°ΠΏΠΈΠΈ, ΠΏΡΠΈΠ²Π΅ΡΠΆΠ΅Π½Π½ΠΎΡΡΠΈ ΠΊ Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΈ ΡΡΠΎΠ²Π½Ρ Π»Π΅ΡΠ°Π»ΡΠ½ΠΎΡΡΠΈ Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΡΡ
ΡΠ°Π·Π»ΠΈΡΠΈΠΉ Π² Π³ΡΡΠΏΠΏΠ°Ρ
ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ Π½Π΅ Π²ΡΡΠ²Π»Π΅Π½ΠΎ.
Future Teachersβ Attitude to the Security Problem and Counter Terrorism
The relevance of the theme under study is determined by the problem of ensuring stability and security of the society through young peopleβs attitude to terrorism. The human community must be able to protect a personβs world outlook, educational, scientific and cultural needs that determine a personβs existence and mental world. One of the key trends in the fight against extremist and terrorist acts in the social environment is their prevention. It is especially important to carry out such preventive measures among young people. The rising generation appears to be the most unprotected category of the population susceptible to the influence of xenophobia destroying traditional values of national cultures and religions which is in a peculiar kind of a spiritual and axiological vacuum. 79 students of 1-5 years of study at the age of 17 - 22 were questioned according to the test-questionnaire βYoung peopleβs attitude to terrorismβ. Almost all respondents (95%) confirmed that terrorism is dangerous for the society and the problem really exists. Most respondents distinguish such qualities as cruelty, mercenariness, quick temper, and instability when describing a terroristβs portrait. When analyzing major reasons why people become terrorists, the students gave the first place to striving to feel power over people. Among other important reasons that influence a terroristβs personality development, they stated commitment to a certain ideology and striving to achieve material wealth. We need an integral system of terrorism prevention including, among other things, its pedagogical foundations.
DOI: 10.5901/mjss.2015.v6n3s7p40
- β¦