1,578 research outputs found
Detecting Spin-Polarized Currents in Ballistic Nanostructures
We demonstrate a mesoscopic spin polarizer/analyzer system that allows the
spin polarization of current from a quantum point contact in an in-plane
magnetic field to be measured. A transverse focusing geometry is used to couple
current from an emitter point contact into a collector point contact. At large
in-plane fields, with the point contacts biased to transmit only a single spin
(g < e^2/h), the voltage across the collector depends on the spin polarization
of the current incident on it. Spin polarizations of greater than 80% are found
for both emitter and collector at 300mK and 7T in-plane field.Comment: related papers at http://marcuslab.harvard.ed
Spin separation in cyclotron motion
Charged carriers with different spin states are spatially separated in a
two-dimensional hole gas. Due to strong spin-orbit interaction holes at the
Fermi energy have different momenta for two possible spin states travelling in
the same direction and, correspondingly, different cyclotron orbits in a weak
magnetic field. Two point contacts, acting as a monochromatic source of
ballistic holes and a narrow detector in the magnetic focusing geometry are
demonstrated to work as a tunable spin filter.Comment: 4 pages, 2 figure
Influence of a Uniform Current on Collective Magnetization Dynamics in a Ferromagnetic Metal
We discuss the influence of a uniform current, , on the
magnetization dynamics of a ferromagnetic metal. We find that the magnon energy
has a current-induced contribution proportional to
, where is the spin-current, and
predict that collective dynamics will be more strongly damped at finite . We obtain similar results for models with and without local moment
participation in the magnetic order. For transition metal ferromagnets, we
estimate that the uniform magnetic state will be destabilized for . We discuss the relationship of this effect to
the spin-torque effects that alter magnetization dynamics in inhomogeneous
magnetic systems.Comment: 12 pages, 2 figure
Hemispheric Asymmetry in New Neurons in Adulthood Is Associated with Vocal Learning and Auditory Memory
Many brain regions exhibit lateral differences in structure and function, and also incorporate new neurons in adulthood, thought to function in learning and in the formation of new memories. However, the contribution of new neurons to hemispheric differences in processing is unknown. The present study combines cellular, behavioral, and physiological methods to address whether 1) new neuron incorporation differs between the brain hemispheres, and 2) the degree to which hemispheric lateralization of new neurons correlates with behavioral and physiological measures of learning and memory. The songbird provides a model system for assessing the contribution of new neurons to hemispheric specialization because songbird brain areas for vocal processing are functionally lateralized and receive a continuous influx of new neurons in adulthood. In adult male zebra finches, we quantified new neurons in the caudomedial nidopallium (NCM), a forebrain area involved in discrimination and memory for the complex vocalizations of individual conspecifics. We assessed song learning and recorded neural responses to song in NCM. We found significantly more new neurons labeled in left than in right NCM; moreover, the degree of asymmetry in new neuron numbers was correlated with the quality of song learning and strength of neuronal memory for recently heard songs. In birds with experimentally impaired song quality, the hemispheric difference in new neurons was diminished. These results suggest that new neurons may contribute to an allocation of function between the hemispheres that underlies the learning and processing of complex signals
Gramella portivictoriae sp nov, a novel member of the family Flavobacteriaceae isolated from marine sediment (vol 55, pg 2497, 2005)
A yellow-pigmented, Gram-negative, slowly gliding, rod-shaped, strictly aerobic bacterium
(UST040801-001T) was isolated from marine sediment. The DNA G+C content was 39?9 mol%.
The predominant fatty acids were a15 : 0, i15 : 0, i15 : 0 3-OH, i17 : 1v9c, i17 : 0 3-OH and
summed feature 3, comprising i15 : 0 2-OH and/or 16 : 1v7c (altogether representing 76?2% of
the total). MK-6 was the only respiratory quinone. Flexirubin-type pigments were not produced.
Phylogenetic analysis based on 16S rRNA gene sequences indicated that Gramella echinicola
KMM 6050T (the only species in the genus) was the closest relative of UST040801-001T,
sharing 98?0% sequence similarity. The DNA–DNA relatedness between UST040801-001T and
Gramella echinicola KMM 6050T was 13 %. Strain UST040801-001T can be distinguished
from G. echinicola by means of 11 phenotypic traits. The results of molecular and phenotypic
analyses suggested that UST040801-001T represents a novel species of Gramella. The name
Gramella portivictoriae sp. nov. is proposed for this bacterium, with UST040801-001T
(=NRRL 41137T=JCM 13192T) as the type strain
Electron focusing, mode spectroscopy and mass enhancement in small GaAs/AlGaAs rings
A new electron focusing effect has been discovered in small single and
coupled GaAs/AlGaAs rings. The focusing in the single ring is attributed solely
to internal orbits. The focusing effect allows the ring to be used as a small
mass spectrometer. The focusing causes peaks in the magnetoresistance at low
fields, and the peak positions were used to study the dispersion relation of
the one-dimensional magnetoelectric subbands. The electron effective mass
increases with the applied magnetic field by a factor of , at a magnetic
field of . This is the first time this increase has been measured
directly. General agreement obtains between the experiment and the subband
calculations for straight channels.Comment: 13 pages figures are available by reques
The global, regional, and national burden of cirrhosis by cause in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017
Background Cirrhosis and other chronic liver diseases (collectively referred to as cirrhosis in this paper) are a major cause of morbidity and mortality globally, although the burden and underlying causes differ across locations and demographic groups. We report on results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 on the burden of cirrhosis and its trends since 1990, by cause, sex, and age, for 195 countries and territories.
Methods We used data from vital registrations, vital registration samples, and verbal autopsies to estimate mortality. We modelled prevalence of total, compensated, and decompensated cirrhosis on the basis of hospital and claims data. Disability-adjusted life-years (DALYs) were calculated as the sum of years of life lost due to premature death and years lived with disability. Estimates are presented as numbers and age-standardised or age-specific rates per 100 000 population, with 95% uncertainty intervals (UIs). All estimates are presented for five causes of cirrhosis: hepatitis B, hepatitis C, alcohol-related liver disease, non-alcoholic steatohepatitis (NASH), and other causes. We compared mortality, prevalence, and DALY estimates with those expected according to the Socio-demographic Index (SDI) as a proxy for the development status of regions and countries.
Findings In 2017, cirrhosis caused more than 1.32 million (95% UI 1.27-1.45) deaths (440000 [416 000-518 000; 33.3%] in females and 883 000 [838 000-967 000; 66.7%] in males) globally, compared with less than 899 000 (829 000-948 000) deaths in 1990. Deaths due to cirrhosis constituted 2.4% (2.3-2.6) of total deaths globally in 2017 compared with 1.9% (1.8-2.0) in 1990. Despite an increase in the number of deaths, the age-standardised death rate decreased from 21.0 (19.2-22.3) per 100 000 population in 1990 to 16.5 (15.8-18-1) per 100 000 population in 2017. Sub-Saharan Africa had the highest age-standardised death rate among GBD super-regions for all years of the study period (32.2 [25.8-38.6] deaths per 100 000 population in 2017), and the high-income super-region had the lowest (10.1 [9.8-10-5] deaths per 100 000 population in 2017). The age-standardised death rate decreased or remained constant from 1990 to 2017 in all GBD regions except eastern Europe and central Asia, where the age-standardised death rate increased, primarily due to increases in alcohol-related liver disease prevalence. At the national level, the age-standardised death rate of cirrhosis was lowest in Singapore in 2017 (3.7 [3.3-4.0] per 100 000 in 2017) and highest in Egypt in all years since 1990 (103.3 [64.4-133.4] per 100 000 in 2017). There were 10.6 million (10.3-10.9) prevalent cases of decompensated cirrhosis and 112 million (107-119) prevalent cases of compensated cirrhosis globally in 2017. There was a significant increase in age-standardised prevalence rate of decompensated cirrhosis between 1990 and 2017. Cirrhosis caused by NASH had a steady age-standardised death rate throughout the study period, whereas the other four causes showed declines in age-standardised death rate. The age-standardised prevalence of compensated and decompensated cirrhosis due to NASH increased more than for any other cause of cirrhosis (by 33.2% for compensated cirrhosis and 54.8% for decompensated cirrhosis) over the study period. From 1990 to 2017, the number of prevalent cases snore than doubled for compensated cirrhosis due to NASH and more than tripled for decompensated cirrhosis due to NASH. In 2017, age-standardised death and DALY rates were lower among countries and territories with higher SDI.
Interpretation Cirrhosis imposes a substantial health burden on many countries and this burden has increased at the global level since 1990, partly due to population growth and ageing. Although the age-standardised death and DALY rates of cirrhosis decreased from 1990 to 2017, numbers of deaths and DALYs and the proportion of all global deaths due to cirrhosis increased. Despite the availability of effective interventions for the prevention and treatment of hepatitis B and C, they were still the main causes of cirrhosis burden worldwide, particularly in low-income countries. The impact of hepatitis B and C is expected to be attenuated and overtaken by that of NASH in the near future. Cost-effective interventions are required to continue the prevention and treatment of viral hepatitis, and to achieve early diagnosis and prevention of cirrhosis due to alcohol-related liver disease and NASH
Stenothermobacter spongiae gen. nov., sp. nov., a novel member of the family Flavobacteriaceae isolated from a marine sponge in the Bahamas, and emended description of Nonlabens tegetincola
A bacterial strain, UST030701-156T, was isolated from a marine sponge in the Bahamas. Strain UST030701-156T was orange-pigmented, Gram-negative, rod-shaped with tapered ends, slowly motile by gliding and strictly aerobic. The predominant fatty acids were a15 : 0, i15 : 0, i15 : 0 3-OH, i17 : 0 3-OH, i17 : 1ω9c and summed feature 3, comprising i15 : 0 2-OH and/or 16 : 1ω7c. MK-6 was the only respiratory quinone. Flexirubin-type pigments were not produced. Phylogenetic analysis based on 16S rRNA gene sequences placed UST030701-156T within a distinct lineage in the family Flavobacteriaceae, with 93·3 % sequence similarity to the nearest neighbour, Nonlabens tegetincola. The DNA G+C content of UST030701-156T was 41·0 mol% and was much higher than that of N. tegetincola (33·6 mol%). Strain UST030701-156T can be distinguished from other members of the Flavobacteriaceae by means of a number of chemotaxonomic and phenotypic characteristics. It is proposed, therefore, that UST030701-156T represents a novel taxon designated Stenothermobacter spongiae gen. nov., sp. nov. The type strain is UST030701-156T (=NRRL B-41138T=JCM 13191T). Carbon-source utilization by N. tegetincola was re-examined and an emended description is therefore included
Description of Fabibacter halotolerans gen. nov., and reclassification of [Marinicola] seohaensis as Roseivirga seahaensis comb. nov.
Bacterial strains UST030701-097T and UST030701-084T were isolated from a marine sponge in the Bahamas. Both strains were pink-pigmented, Gram-negative, strictly aerobic and chemo-organotrophic. Cells of strain UST030701-097T were short, curved rods with fast-gliding motility, whereas those of strain UST030701-084T were straight rods with a less rapid gliding motion. The two strains had MK-7 as the major respiratory quinone and did not produce flexirubin-type pigments. The DNA G+C contents of strains UST030701-097T and UST030701-084T were 42.5 and 43.7 mol%, respectively. Phylogenetic analysis based on 16S rRNA gene sequences indicated that the two strains belonged to the family 'Flexibacteraceae' of the phylum Bacteroidetes. 16S rRNA gene sequence similarity between strains UST030701-097T and UST030701-084T was 95.0 %; their closest relative was [Marinicola] seohaensis, with 93.3 % and 96.0 % sequence similarity, respectively. Phylogenetic tree topology indicated that the two strains belonged to the same lineage, but were on separate branches. Whilst strain UST030701-084T and [Marinicola] seohaensis were found on one branch, strain UST030701-097T was in another branch that had no species with validly published names. Based on the polyphasic taxonomic data obtained in the present study, we propose that strain UST030701-097T represents a novel genus and that strain UST030701-084T represents a novel species in the phylum Bacteroidetes. The genus Fabibacter gen. nov. is proposed, with strain UST030701-097T (=NRRL B-41220T=JCM 13334T) as the type strain of the type species, Fabibacter halotolerans sp. nov. Strain UST030701-084T (=NRRL B-41219T=JCM 13337T) is proposed as the type strain of Roseivirga spongicola sp. nov. In an earlier study, it was suggested that the genus Marinicola is a later heterotypic synonym of the genus Roseivirga. However, a formal proposal to reclassify [Marinicola] seohaensis, the only member of the genus Marinicola, has not yet been made. The results of phylogenetic analyses in this study support the reclassification of [Marinicola] seohaensis as Roseivirga seohaensis comb. nov
Nanolithography based on real-time electrically-controlled indentation with an atomic force microscope for nanocontacts elaboration
We report on the fabrication of nanocontacts by indentation of an ultrathin
insulating photoresist layer deposited on various types of conductive
structures. A modified atomic force microscope (AFM) designed for local
resistance measurements is used as a nanoindenter. The nanoindentation is
performed while measuring continuously the resistance between the conductive
tip of the AFM and the conductive layer, which is used as the trigger parameter
to stop the indentation. This allows an extremely accurate control of the
indentation process. The indented hole is subsequently filled by a metal to
create a contact on the underlying layer. We show that nanocontacts in the
range of 1 to 10 nm2 can be created with this technique
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