Функціональний стан м’язів зубощелепного апарату до та після лікування дітей з аномаліями прикусу та мовленнєвими порушеннями

During the examination of orthodontic patients, children with speech disorders were found. The myodynamic balance of antagonistic muscles and synergistic muscles is the relative stability of masticatory and mimic muscles, which for a long time persists without noticeable oscillations, contributes to the relatively stable state of dentoalveolar apparatus. The aim of the study – to determine the functional status of muscles of the dentoalveolar apparatus before and after treatment of children with anomalies of bite and speech disorders. Materials and Methods. To achieve study objectives for treatment we selected 44 patients with severe orthodontic pathology and speech disorders, with normal hearing and intellect. The method of a total (surface) electromyography was used to determine and analyze the indices of bioelectric activity of the muscles. Results and Discussion. There was normalization of parameters of bioelectric activity, decrease of parafunctional manifestations in muscles and decrease of the frequency of outbreaks of spontaneous activity of muscles at rest; normalization of the average amplitude of biopotentials in the state of activity, absence of fragmentation, improvement of synchronization and coordination of contractions of examined muscles in all pathologies of dental occlusion after the treatment. Conclusions. The orthodontic treatment performed provided the restoration of the neuromuscular balance of the dentoalveolar apparatus of patients with various dental occlusion pathologies, which has a beneficial effect on the correction of speech disorders.При обследовании ортодонтических пациентов были дети с речевыми нарушениями. Миодинамическое равновесие мышц-антагонистов и синергистов – это относительная устойчивость жевательных и мимических мышц, которая в течении длительного времени сохраняется без заметных изменений, способствует относительной стабильности зубочелюстного аппарата. Цель исследования – определить функциональное состояние мышц зубочелюстного аппарата до и после лечения детей с аномалиями прикуса и речевыми нарушениями. Материалы и методы. Для достижения поставленной цели было принято на лечение 44 пациента с выраженной ортодонтической патологией и речевыми нарушениями с нормальным слухом и интеллектом. Для определения и анализа показателей биоэлектрической активности мышц использован метод суммарной (поверхностной) электромиографии. Результаты исследований и их обсуждение. После проведённого лечения наблюдали нормализацию показателей биоэлектрической активности, уменьшение парафункциональних проявлений в мышцах и частоты вспышек спонтанной активности мышц в состоянии покоя, нормализация средней амплитуды биопотенциалов в состоянии активности, отсутствие фрагментаций, улучшение синхронности и координации сокращений обследованных мышц при всех патологиях прикуса. Выводы. Проведённое ортодонтическое лечение обеспечило восстановление нейромышечного баланса зубочелюстного аппарата пациентов с различными патологиями прикуса, что имеет благоприятное воздействие на коррекцию речевых нарушений.Під час обстеження ортодонтичних пацієнтів були діти з мовленнєвими порушеннями. Міодинамічна рівновага м’язів-антагоністів та синергістів – це відносна стійкість жувальних та мімічних м’язів, що протягом тривалого часу зберігається без помітних коливань, сприяє відносно стабільного стану зубощелепного апарату. Мета дослідження – визначити функціональний стан м’язів зубощелепного апарату до та після лікування дітей з аномаліями прикусу та мовленнєвими порушеннями. Матеріали і методи. Для досягнення поставленої мети було прийнято на лікування 44 пацієнти з вираженою ортодонтичною патологією та мовленнєвими порушеннями із нормальним слухом та інтелектом. Для визначення та аналізу показників біоелектричної активності м’язів використано метод сумарної (поверхневої) електроміографії. Результати досліджень та їх обговорення. Після проведеного лікування спостерігали нормалізацію показників біоелектричної активності, зменшення парафункціональних проявів у м’язах та частоти спалахів спонтанної активності м’язів у стані спокою, нормалізація середньої амплітуди біопотенціалів у стані активності, відсутність фрагментацій, покращення синхронності та координації скорочень обстежених м’язів при усіх патологіях прикусу. Висновки. Проведене ортодонтичне лікування забезпечило відновлення нейром’язового балансу зубощелепного апарату пацієнтів із різними патологіями прикусу, що має сприятливий вплив на корекцію мовленнєвих порушень

The origin of paramagnetic magnetization in field-cooled YBa2Cu3O7 films

Temperature dependences of the magnetic moment have been measured in YBa_2Cu_3O_{7-\delta} thin films over a wide magnetic field range (5 <= H <= 10^4 Oe). In these films a paramagnetic signal known as the paramagnetic Meissner effect has been observed. The experimental data in the films, which have strong pinning and high critical current densities (J_c ~ 2 \times 10^6 A/cm^2 at 77 K), are quantitatively shown to be highly consistent with the theoretical model proposed by Koshelev and Larkin [Phys. Rev. B 52, 13559 (1995)]. This finding indicates that the origin of the paramagnetic effect is ultimately associated with nucleation and inhomogeneous spatial redistribution of magnetic vortices in a sample which is cooled down in a magnetic field. It is also shown that the distribution of vortices is extremely sensitive to the interplay of film properties and the real experimental conditions of the measurements.Comment: RevTex, 8 figure

DETERMINATION OF OPTIMIZATION WAYS OF RE-PROTHESIS USING VARIOUS SCHEMES GNATHOLOGICAL SUPPORT OF PATIENTS AT THE PREPARATORY STAGE TO THE ORTHOPEDIC CORRECTION OF PATIENTS WITH OCCLUSIVE IATROGENIC DISORDERS OF TOOTH-JAW APPARATUS

We brought to the light that one of the the most controversial issues is the moment of adaptation to reconstructive procedures. Often it becomes unclear which and in which order to use medical diagnostic equipment, to training for fixed prosthetic stages. Our studies make it possible to predict not only the treatment time, but the amount of occlusal adjustment in conjunction with the reconstruction of the position of the mandible.One of the most debated issues is the time of adaptation to reconstructive manipulation. Often it becomes unclear how and in what order medical diagnostic equipment should be used in the preparatory stages of the stationary prosthetics. Our studies make it possible to predict not only the treatment time, and the amount of occlusal adjustment in conjunction with the reconstruction of the lower jaw. Keywords: tooth-jaw apparatus, temporomandibular joint, violation functional occlusion, dental surgery, medical diagnostic devices, muscle disorders, adaptation, occlusal splint, occlusal adjustment, chewing muscles, provisional design

Genotypic and ecological variability of zinc content in the grain of spring bread wheat varieties in the international nursery KASIB

Spring bread wheat is the staple crop in Western Siberia and Kazakhstan, a significant portion of which goes for export. Wheat breeding with a high level of zinc in wheat grain is the most cost-effective and environmentally friendly way to address zinc de iciency in the diet. The purpose of this work was to evaluate the contribution of the factors ‘location’ and ‘genotype’ in the variability of zinc content in wheat grain, and to identify the best varieties as sources of this trait for breed-ing. The research on screening zinc content in the wheat grain of 49 spring bread wheat varieties from the Kazakhstan-Siberia Spring Wheat Trial (KASIB) nursery was carried out at 4 sites in Russia (Chelyabinsk, Omsk, Tyumen, Novosibirsk) and 2 sites in Kazakhstan (Karabalyk and Shortandy) in 2017–2018. The content of zinc in wheat grain was evaluated at the Ionomic Facility of University of Nottingham in the framework of the EU pro ject European Plant Phenotyping Network-2020. The analysis of variance showed that the main contribution into the general phenotypic variation of the studied trait, 38.7 %, was made by the factor ‘location’ due to different contents of zinc and moisture in the soil of trial sites; the effect of the factor ‘year’ was 13.5 %, and the effect of the factor ‘genotype’ was 8.0 %. The most favorable environmental conditions for accumulation of zinc in wheat grain were observed in the Omsk region. In Omsk, the average zinc content in all studied varieties was 50.4 mg/kg, with 63.7 mg/ kg in the best variety ‘OmGAU 100’. These values are higher than the target values of the international program Harvest Plus. ‘Novosibirskaya 16’ (49.4 mg/kg), ‘Silach’ (48.4 mg/kg), ‘Line 4-10-16’ (47.2 mg/ kg), ‘Element 22’ (46.3 mg/kg) and ‘Lutescens 248/01’ (46.0 mg/kg) were identi ied as being the best varieties. Significant possibilities for the production of wheat grain with high zinc content, which is in demand for the production of bread and pastry products with functional properties, were identified in the Western Siberian region

All-sky search for time-integrated neutrino emission from astrophysical sources with 7 years of IceCube data

Since the recent detection of an astrophysical flux of high energy neutrinos, the question of its origin has not yet fully been answered. Much of what is known about this flux comes from a small event sample of high neutrino purity, good energy resolution, but large angular uncertainties. In searches for point-like sources, on the other hand, the best performance is given by using large statistics and good angular reconstructions. Track-like muon events produced in neutrino interactions satisfy these requirements. We present here the results of searches for point-like sources with neutrinos using data acquired by the IceCube detector over seven years from 2008--2015. The discovery potential of the analysis in the northern sky is now significantly below $E_\nu^2d\phi/dE_\nu=10^{-12}\:\mathrm{TeV\,cm^{-2}\,s^{-1}}$, on average $38\%$ lower than the sensitivity of the previously published analysis of four years exposure. No significant clustering of neutrinos above background expectation was observed, and implications for prominent neutrino source candidates are discussed.Comment: 19 pages, 17 figures, 3 tables; ; submitted to The Astrophysical Journa

Neutrinos and Cosmic Rays Observed by IceCube

The core mission of the IceCube Neutrino observatory is to study the origin and propagation of cosmic rays. IceCube, with its surface component IceTop, observes multiple signatures to accomplish this mission. Most important are the astrophysical neutrinos that are produced in interactions of cosmic rays, close to their sources and in interstellar space. IceCube is the first instrument that measures the properties of this astrophysical neutrino flux, and constrains its origin. In addition, the spectrum, composition and anisotropy of the local cosmic-ray flux are obtained from measurements of atmospheric muons and showers. Here we provide an overview of recent findings from the analysis of IceCube data, and their implications on our understanding of cosmic rays.Comment: Review article, to appear in Advances in Space Research, special issue "Origins of Cosmic Rays

Lowering IceCube’s energy threshold for point source searches in the southern sky

Observation of a point source of astrophysical neutrinos would be a "smoking gun" signature of a cosmic-ray accelerator. While IceCube has recently discovered a diffuse flux of astrophysical neutrinos, no localized point source has been observed. Previous IceCube searches for point sources in the southern sky were restricted by either an energy threshold above a few hundred TeV or poor neutrino angular resolution. Here we present a search for southern sky point sources with greatly improved sensitivities to neutrinos with energies below 100 TeV. By selecting charged-current nu(mu) interacting inside the detector, we reduce the atmospheric background while retaining efficiency for astrophysical neutrino-induced events reconstructed with sub-degree angular resolution. The new event sample covers three years of detector data and leads to a factor of 10 improvement in sensitivity to point sources emitting below 100 TeV in the southern sky. No statistically significant evidence of point sources was found, and upper limits are set on neutrino emission from individual sources. A posteriori analysis of the highest-energy (similar to 100 TeV) starting event in the sample found that this event alone represents a 2.8 sigma deviation from the hypothesis that the data consists only of atmospheric background

Search for astrophysical sources of neutrinos using cascade events in IceCube

The IceCube neutrino observatory has established the existence of a flux of high-energy astrophysical neutrinos inconsistent with the expectation from atmospheric backgrounds at a significance greater than $5\sigma$. This flux has been observed in analyses of both track events from muon neutrino interactions and cascade events from interactions of all neutrino flavors. Searches for astrophysical neutrino sources have focused on track events due to the significantly better angular resolution of track reconstructions. To date, no such sources have been confirmed. Here we present the first search for astrophysical neutrino sources using cascades interacting in IceCube with deposited energies as small as 1 TeV. No significant clustering was observed in a selection of 263 cascades collected from May 2010 to May 2012. We show that compared to the classic approach using tracks, this statistically-independent search offers improved sensitivity to sources in the southern sky, especially if the emission is spatially extended or follows a soft energy spectrum. This enhancement is due to the low background from atmospheric neutrinos forming cascade events and the additional veto of atmospheric neutrinos at declinations $\lesssim-30^\circ$.Comment: 14 pages, 9 figures, 1 tabl