Pengaruh Lingkungan Kerja Non Fisik terhadap Kepuasan Kerja Dosen Tetap Studi pada Fakultas Komunikasi dan Bisnis Universitas Telkom Bandung

The purpose of this study is to determine the influence of non-physical work environment on job satisfaction lecturer of the Faculty of Communication and Business at the University of Telkom Bandung. The independentvariable X of the study is non-physical work environment while the dependent variable Y is job satisfaction. The data are obtained by distributing questionnaires, sampling technique uses the saturation. The analytical method used is a simple linear regression analysis method.The research results prove that the non-physical work environment by 38.8% have influence on job satisfaction lecturer of the Faculty of Communication and Business, University of Telkom Bandung and theremaining 61.2% is influenced by other factors that are not observed in this study. In other words, there is a partial effect of non-physical work environment on permanent lecturers’ job satisfaction on the Faculty ofCommunication and Business, University of Telkom Bandung

Pemetaan Kesesuaian Lahan untuk Tanaman Pangan di Kecamatan Soyo Jaya Kabupaten Morowali Utara

This study aims to map land suitability classes for the development of food crops, especially crops Rice (Oryza sativa) in the Soyo Jaya Subdistrict, Morowali Utara District. This research is useful for information and recommendations about the suitability of land as well a basis for the development of crop cultivation Rice (Oryza sativa). This study was conducted from November to March 2016, located in the Soyo Jaya Subdistrict, Morowali Utara District. The research method used is a survey method of conducting surveys directly in the field. Grouping of land suitability classes on each unit of land use systems based on the key criteria of land suitability for crops Rice (Oryza sativa). The results showed that the actual land suitability classes are S3rfne (marginally suitable) with 36,123.54 hectare land area, while the potential land suitability class is S2rfne (appropriately enough) and the actual land suitability classes N1re (not appropriate at this time) with an area 18,761.58 hectares, while the potential land suitability class is S3re

Pembuatan Bilayer Anode (Nio-csz) - Elektrolit Csz Dengan Metode Electrophoretic Deposition

PEMBUATAN BILAYER ANODE (NiO-CSZ) - ELEKTROLIT CSZ DENGAN METODE ELECTROPHORETIC DEPOSITION. Telah dilakukan pembuatan bilayer anode NiO-CSZ - elektrolit CSZ dengan metode Electrophoretic Deposition (EPD). Substrat (anode) NiO-CSZ dibuat dengan metode pressing dan elektrolit CSZ ditumbuhkan di atas substrat NiO-CSZ dengan metode EPD. Elektrolit CSZ ditumbuhkan di atas substrat NiO-CSZ dengan variasi waktu deposisi masing-masing 10 menit, 20 menit, dan 30 menit dan disinter pada suhu 1250oC. Dari analisis yang dilakukan menggunakan X-Ray Diffractometer (XRD), diketahui terdapat 3 fasa yakni CSZ, Ni, dan NiO pada bilayer NiO-CSZ/CSZ untukwaktu deposisi 30menit. Pemeriksaan ketebalan lapisan CSZ dilakukan menggunakan mikroskop optik. Data foto memperlihatkan bahwa ketebalan lapisan CSZ di atas substrat NiO-CSZ meningkat dengan meningkatnya waktu deposisi. Berdasarkan hasil karakterisasi sifat listrik lapisan CSZ menggunakan LCR meter diketahui bahwa peningkatan waktu deposisi menurunkan nilai konduktivitas ionik lapisan CSZ untuk masing-masing waktu deposisi 10 menit, 20 menit, dan 30 menit sebesar 0,078 mS/cm, 0,062 mS/cm, dan 0,004 mS/cm pada suhu 300 oC

The relationship between nutritional status and menstrual cycle regularity

In adolescence, there is a period called puberty. In young women, puberty is characterized by the onset of the first menstruation that occurs at 10-16 years old. The menstruation cycle is a clinical sign of female reproduction. Normal menstruation cycle length occurs around 21-35 days. Age, nutritional status, stress, and body fat mass affect the menstruation cycle. Less or more nutritional status can cause menstrual cycle irregularities. The aim of the study was to find out the relationship between nutritional status and the regularity of menstruation cycles in female students of the Medical Faculty Indonesia Christian University. The type of this research is an analytical survey with a cross-sectional design. The population of this study was female students of the Medical Faculty Indonesia Christian University. The sampling technique used a random sampling method to obtain 57 respondents. The chi-square statistic test showed a correlation between nutritional status and menstruation cycle regularity because of p-value = 0,000 (p <0.05). The result is that there is a relationship between nutritional status and the regularity of the menstrual cycle in female students of Medical Faculty Indonesia Christian University Class of 2015. Therefore, it is concluded that the female students must begin to know themselves and their bodies and pay attention to body changes by recording the menstrual cycle every month Keywords: menstrual cycles, nutritional statu

HER2 induced EMT and tumorigenicity in breast epithelial progenitor cells is inhibited by coexpression of EGFR.

To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access.The members of the epidermal growth factor receptor (EGFR) kinase family are important players in breast morphogenesis and cancer. EGFR2/HER2 and EGFR expression have a prognostic value in certain subtypes of breast cancer such as HER2-amplified, basal-like and luminal type B. Many clinically approved small molecular inhibitors and monoclonal antibodies have been designed to target HER2, EGFR or both. There is, however, still limited knowledge on how the two receptors are expressed in normal breast epithelium, what effects they have on cellular differentiation and how they participate in neoplastic transformation. D492 is a breast epithelial cell line with stem cell properties that can undergo epithelial to mesenchyme transition (EMT), generate luminal- and myoepithelial cells and form complex branching structures in three-dimensional (3D) culture. Here, we show that overexpression of HER2 in D492 (D492(HER2)) resulted in EMT, loss of contact growth inhibition and increased oncogenic potential in vivo. HER2 overexpression, furthermore, inhibited endogenous EGFR expression. Re-introducing EGFR in D492(HER2) (D492(HER2/EGFR)) partially reversed the mesenchymal state of the cells, as an epithelial phenotype reappeared both in 3D cultures and in vivo. The D492(HER2/EGFR) xenografts grow slower than the D492(HER2) tumors, while overexpression of EGFR alone (D492(EGFR)) was not oncogenic in vivo. Consistent with the EGFR-mediated epithelial phenotype, overexpression of EGFR drove the cells toward a myoepithelial phenotype in 3D culture. The effect of two clinically approved anti-HER2 and EGFR therapies, trastuzumab and cetuximab, was tested alone and in combination on D492(HER2) xenografts. While trastuzumab had a growth inhibitory effect compared with untreated control, the effect of cetuximab was limited. When administered in combination, the growth inhibitory effect of trastuzumab was less pronounced. Collectively, our data indicate that in HER2-overexpressing D492 cells, EGFR can behave as a tumor suppressor, by pushing the cells towards epithelial differentiation.Landspitali University Hospital Science Fund, University of Iceland Research Fund, Science and Technology Policy Council Research Fund and Grant of Excellence, ‘Göngum saman’, a supporting group for breast cancer research in Iceland

Mediated Plastid RNA Editing in Plant Immunity

[EN] Plant regulatory circuits coordinating nuclear and plastid gene expression have evolved in response to external stimuli. RNA editing is one of such control mechanisms. We determined the Arabidopsis nuclear-encoded homeodomain-containing protein OCP3 is incorporated into the chloroplast, and contributes to control over the extent of ndhB transcript editing. ndhB encodes the B subunit of the chloroplast NADH dehydrogenase-like complex (NDH) involved in cyclic electron flow (CEF) around photosystem I. In ocp3 mutant strains, ndhB editing efficiency decays, CEF is impaired and disease resistance to fungal pathogens substantially enhanced, a process recapitulated in plants defective in editing plastid RNAs encoding NDH complex subunits due to mutations in previously described nuclear-encoded pentatricopeptide-related proteins (i.e. CRR21, CRR2). Furthermore, we observed that following a pathogenic challenge, wild type plants respond with editing inhibition of ndhB transcript. In parallel, rapid destabilization of the plastidial NDH complex is also observed in the plant following perception of a pathogenic cue. Therefore, NDH complex activity and plant immunity appear as interlinked processes.This work was supported by the Spanish MICINN (CONSOLIDER and BFU2012 to PV), and Generalitat Valenciana (Prometeo2010/020 to PV). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.García-Andrade Serrano, J.; Ramirez Garcia, V.; López Sánchez, A.; Vera Vera, P. (2013). Mediated Plastid RNA Editing in Plant Immunity. PLoS Pathogens. 9(10):1003713-1003713. https://doi.org/10.1371/ journal.ppat.1003713S1003713100371391