The Investigation of Machinability and Surface Properties of Aluminium Alloy Matrix Composites

Aluminum matrix composites (AMCs) are crucial to the progress of composite application areas due to their remarkable mechanical properties. Their usage has expanded into different fields such as the aerospace, automobile, and defense industries. The present study used wrought Al alloy AA6061 as the matrix, while ilmenite (FeTiO3) particles were used as reinforcement at different weight percentages to prepare metal matrix composites. One of the most economical and simple casting routes among the several available fabrication techniques for the preparation of composites is the stir casting method, which was applied in the present investigation to prepare the AMCs. The machinability of the fabricated composites and the surface roughness property after machining were studied to understand the effect of speed and feed during machining. The results showed that an increase in speed decreased the cutting forces and the surface roughness. Meanwhile, an increase in surface roughness was observed with an increase in feed

Image Description Generator using Residual Neural Network and Long Short-Term Memory

Human beings can describe scenarios and objects in a picture through vision easily whereas performing the same task with a computer is a complicated one. Generating captions for the objects of an image helps everyone to understand the scenario of the image in a better way. Instinctively describing the content of an image requires the apprehension of computer vision as well as natural language processing. This task has gained huge popularity in the field of technology and there is a lot of research work being carried out. Recent works have been successful in identifying objects in the image but are facing many challenges in generating captions to the given image accurately by understanding the scenario. To address this challenge, we propose a model to generate the caption for an image. Residual Neural Network (ResNet) is used to extract the features from an image. These features are converted into a vector of size 2048. The caption generation for the image is obtained with Long Short-Term Memory (LSTM). The proposed model is experimented on the Flickr8K dataset and obtained an accuracy of 88.4\%. The experimental results indicate that our model produces appropriate captions compared to the state of art models

Searching For Dark Matter with Plasma Haloscopes

We summarise the recent progress of the Axion Longitudinal Plasma HAloscope (ALPHA) Consortium, a new experimental collaboration to build a plasma haloscope to search for axions and dark photons. The plasma haloscope is a novel method for the detection of the resonant conversion of light dark matter to photons. ALPHA will be sensitive to QCD axions over almost a decade of parameter space, potentially discovering dark matter and resolving the Strong CP problem. Unlike traditional cavity haloscopes, which are generally limited in volume by the Compton wavelength of the dark matter, plasma haloscopes use a wire metamaterial to create a tuneable artificial plasma frequency, decoupling the wavelength of light from the Compton wavelength and allowing for much stronger signals. We develop the theoretical foundations of plasma haloscopes and discuss recent experimental progress. Finally, we outline a baseline design for ALPHA and show that a full-scale experiment could discover QCD axions over almost a decade of parameter space.Comment: Endorsers: Jens Dilling, Michael Febbraro, Stefan Knirck, and Claire Marvinney. 26 pages, 17 figures, version accepted in Physical Review

T Regulatory Cells Control Susceptibility to Invasive Pneumococcal Pneumonia in Mice

Streptococcus pneumoniae is an important human pathogen responsible for a spectrum of diseases including pneumonia. Immunological and pro-inflammatory processes induced in the lung during pneumococcal infection are well documented, but little is known about the role played by immunoregulatory cells and cytokines in the control of such responses. We demonstrate considerable differences in the immunomodulatory cytokine transforming growth factor (TGF)-β between the pneumococcal pneumonia resistant BALB/c and susceptible CBA/Ca mouse strains. Immunohistochemistry and flow cytometry reveal higher levels of TGF-β protein in BALB/c lungs during pneumococcal pneumonia that correlates with a rapid rise in lung Foxp3+Helios+ T regulatory cells. These cells have protective functions during pneumococcal pneumonia, because blocking their induction with an inhibitor of TGF-β impairs BALB/c resistance to infection and aids bacterial dissemination from lungs. Conversely, adoptive transfer of T regulatory cells to CBA/Ca mice, prior to infection, prolongs survival and decreases bacterial dissemination from lungs to blood. Importantly, strong T regulatory cell responses also correlate with disease-resistance in outbred MF1 mice, confirming the importance of immunoregulatory cells in controlling protective responses to the pneumococcus. This study provides exciting new evidence for the importance of immunomodulation during pulmonary pneumococcal infection and suggests that TGF-β signalling is a potential target for immunotherapy or drug design

Toxoplasma gondii virulence is predictable in cultured human cells.36523

Toxoplasma gondii virulence is predictable in cultured human cells.</p

Effect of vitamin E level and dietary zinc source on performance and intestinal health parameters in male broilers exposed to a temperature challenge in the finisher period

The objective of this study was to evaluate the interaction of zinc source (ZnSO4 vs. zinc amino acid complex) and vitamin E level (50 IU vs. 100 IU) on performance and intestinal health of broilers exposed to a temperature challenge in the finisher period. A total of 1224 day old male Ross 308 broilers were randomly distributed among 4 dietary treatments (9 replicates per treatment). Dietary treatments were organized in a 2 x 2 factorial arrangement: two sources of zinc, 60 mg/kg of Zn as ZnSO4.7H(2)O or 60 mg/kg of Zn as zinc amino acid complexes (ZnAA) combined with two levels of vitamin E (50 or 100 IU/kg). Zinc and vitamin E were added to a wheat/rye-based diet that was designed to create a mild nutritional challenge. From day 28 until day 36 (finisher period), all birds were subjected to chronic cyclic high temperatures (32 degrees C +/- 2 degrees C and RH 55-65% for 6 h daily). The combination of ZnAA and 50 IU/kg of vitamin E improved weight gain in the starter (day 0-10), finisher (day 28-36) and overall period (day 0-36) and feed conversion ratio in the starter (day 0-10) and finisher phase (day 28-36). Providing Zn as ZnAA significantly improved villus length and villus/crypt ratio in the starter, grower and finisher period and decreased infiltration of T-lymphocytes and ovotransferrin leakage in the finisher period. In conclusion, providing broilers with a diet supplemented with ZnAA and a vitamin E level of 50 IU/kg, resulted in better growth performance as compared to all other dietary treatments. Interestingly, under the conditions of this study, positive effects of ZnAA on performance did not occur when vitamin E was supplemented at 100 IU/kg in feed. Moreover, providing zinc as zinc amino acid complex improved intestinal health