735 research outputs found

    The Importance of Digital Skills in Education in the COVID-19 Era

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    Education is a fundamental right and we have to make sure we hold on to it despite any crisis and beyond. Just like in all the world, Kosovo has been affected by the pandemic COVID -19 in March 2020. The pandemic situation has changed how things function and it looks like this is going to be a new normal. As a result of it, all industries including the educational institutions, those private and public, had to reimagine how to switch into online performance and computer-based learning. Online learning has served as a lever to continue with education in an online platform and teachers worked hard to expect growth and productivity in every student. It is worth mentioning that since Kosovo became an independent country, we have never witnessed the educational disruption on this scale. We cannot predict exactly what the future information society will look like but at this time due to COVID -19 the world has experienced a new way of living and together with it we are witnessing the importance of having digital skills as a revolution which is impacting every industry but also in a dramatic way, in the field of education. How the education continued during the pandemic of COVID - 19, in Kosovo has raised different voices in education development during the second semester of the academic year 2019/2020. This paper will discuss the problems and challenges of teaching and learning during the pandemic time, the importance of digital skill and digitalization as a backup plan, and as a solution, so the education must not freeze in time as this

    Is Methacholine Challenge Superior to Exhaled Nitric Oxide in the Evaluation of a Cough Variant Asthma? The Attitude Regarding its Management

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    Background: The aim of our study was the follow up of a patient presented only with dry chronic cough:Which is the main diagnostic procedure and the most effective therapeutic approach available for such patients at the first medical visit and during his follow up? Methods: Seventy patients (21 males and 49 females) age of 40, 47 year, presented only with chronic non productive cough were studied. They did accomplish 3 medical controls for a period of 8 months with a distance of 4 months from each other. A detailed history was taken to evaluate the existence of other contributing factors to chronic cough such as: Asthma, GERD, PNDS, and any respiratory infections. Only 65.71% of them accepted to undergo the Methacholline challenge test and the measurement of Exhaled nitric oxid. Results: From 41 patients who at the first visit were considered to have Cough Variant Asthma (CVA), 47.14% resulted to have GERD as a cofactor to cough and 42.86% resulted to have PNDS as a cofactor. The methacolline challenge test resulted to be positive in 89.13% of the patients at the first visit toward 62.85% who resulted positive at the third visit (p<0.05). The value of Exhaled nitric oxid was elevated at the first visit only in 51.28% of the patients toward 50% who had a high level of it at the third visit. Conclusion: and discussion GERD remains still the most frequent cofactor of chronic productive cough as a variant of asthma.Keywords: Asthma, methacholine, oxid nitric, cough, GERD

    Metodología de las palabras conexivas.

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    El artículo se propone llegar a una clara comprensión de la función de las palabras conexivas españolas y su correcta utilización en el lenguaje oral y ese rito. PA LA BRAS CLA VE: Palabras conexivas. Preposición. Conjunción. tun (`zoiz. litilízacion correcta

    Enfermedades infecciosas gastrointestinales

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    El presente trabajo fue realizado en el Servicio de Internación Pediátrica NºII del Hospital Dr. Humberto Notti, ubicado en Banderas de los Andes 2603, en el departamento de Guaymallén. Está orientado a investigar la relación que existe entre la aparición de infecciones gastrointestinales y el origen social, tomando como muestra a los pacientes menores de 5 años internados en dicho servicio comprendidos entre los meses de septiembre, octubre y noviembre de 2013. El objetivo de esta investigación es encontrar y determinar la relación que existe entre las variables mencionadas anteriormente, como así también determinar y valorar los conocimientos previos que poseen los familiares del paciente, acerca de factores importantes que pueden influir como el lavado de manos, manipulación de alimentos y nutrición; es decir describir el aspecto socio cultural de los mismos.Fil: Lama, Janet M.. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Escuela de Enfermería..Fil: Mancilla, Liliana. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Escuela de Enfermería..Fil: Castro, Romina V.. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Escuela de Enfermería.

    Design and Development of a Fingerprint Based Exam Hall Authentication System

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    Fingerprint exam hall authentication system is a system designed to allow valid users to the exam hall and block invalid users after their fingerprint scan authentication. This system offers an alternative solution to conventional paper type exam authentication. Besides, this system can also be utilized as an attendance system by storing and comparing the database of the students. Traditional paper type exam authentication and attendance list is sometimes regarded as unreliable due to paper lost or proxy attendance system. This system has been running with a R305 fingerprint scanner module and an ATmega328P microcontroller main board connected with several inputs/outputs. Barrel type push buttons are the inputs and LCD, buzzer and solenoid are the outputs used in the design. The system can be operated by push buttons or using Android app to control several operations such as fingerprint enrollment, verification and deletion. The Android app operates in similar way wirelessly by connecting to Bluetooth module but it has additional feature such as student attendance databases management and storing as well as PDF file export. The design can be operated as standalone and handheld method with both hardware and Android app is successfully implemented by using the prototype

    Improving Automatic Melanoma Diagnosis using Deep Learning-Based Segmentation of Irregular Networks

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    Deep Learning Has Achieved Significant Success in Malignant Melanoma Diagnosis. These Diagnostic Models Are Undergoing a Transition into Clinical Use. However, with Melanoma Diagnostic Accuracy in the Range of Ninety Percent, a Significant Minority of Melanomas Are Missed by Deep Learning. Many of the Melanomas Missed Have Irregular Pigment Networks Visible using Dermoscopy. This Research Presents an Annotated Irregular Network Database and Develops a Classification Pipeline that Fuses Deep Learning Image-Level Results with Conventional Hand-Crafted Features from Irregular Pigment Networks. We Identified and Annotated 487 Unique Dermoscopic Melanoma Lesions from Images in the ISIC 2019 Dermoscopic Dataset to Create a Ground-Truth Irregular Pigment Network Dataset. We Trained Multiple Transfer Learned Segmentation Models to Detect Irregular Networks in This Training Set. a Separate, Mutually Exclusive Subset of the International Skin Imaging Collaboration (ISIC) 2019 Dataset with 500 Melanomas and 500 Benign Lesions Was Used for Training and Testing Deep Learning Models for the Binary Classification of Melanoma Versus Benign. the Best Segmentation Model, U-Net++, Generated Irregular Network Masks on the 1000-Image Dataset. Other Classical Color, Texture, and Shape Features Were Calculated for the Irregular Network Areas. We Achieved an Increase in the Recall of Melanoma Versus Benign of 11% and in Accuracy of 2% over DL-Only Models using Conventional Classifiers in a Sequential Pipeline based on the Cascade Generalization Framework, with the Highest Increase in Recall Accompanying the Use of the Random Forest Algorithm. the Proposed Approach Facilitates Leveraging the Strengths of Both Deep Learning and Conventional Image Processing Techniques to Improve the Accuracy of Melanoma Diagnosis. Further Research Combining Deep Learning with Conventional Image Processing on Automatically Detected Dermoscopic Features is Warranted

    Immobilization of two endoglucanases from different sources

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    Cellulases are a important family of hydrolytic enzymes which catalyze the bond of cellulose and other related cello-oligosaccharide derivates. Industrial applications require enzymes highly stable and economically viable in terms of reusability. These costs can be reduced by immobilizing the cellulases, offering a potential solution through enzyme recycling and easy recovery. The covalent immobilization of enzymes is reported here: one is commercial cellulase from Aspergillus niger and other one is recombinant enzyme, named CelStrep it because was isolated from a new cellulolytic strain, Streptomyces sp. G12,. The optimal pH for binding is 4.6 for both cellulases and the optimal enzyme concentrations are 1 mg/mL and 5 mg/mL respectively. The support for immobilization is a poliacrylic matrix. Experiments carried out in this work show positive results of enzyme immobilization in terms of efficiency and stability and confirm the economic and biotechnical advantages of enzyme immobilization for a wide range of industrial applications

    La interrupción de las peregrinaciones etíopes a Tierra Santa en el contexto de la rivalidad entre otomanos y portugueses a principios del siglo XVI

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    From the earliest days of Christianity, Jerusalem was the main destination for Christian pilgrimages. Those that left from the western countries are well known today due to the considerable abundance of pilgrim tales. However, for geographical, political and linguistic reasons, Ethiopian Christians carried out in the Holy Land during the Middle Ages and early modern times are little known. For this reason, an exceptional importance should be given to the story of Francisco Alvares that was spread throughout Europe about the fortune of two pilgrimages that were heading to Jerusalem from the country of Preste Juan. This story is an incomparable testimony to the political, military and religious tensions that occurred in the Red Sea environment at the beginning of the 16th century.Desde los primeros tiempos del cristianismo, Jerusalén fue el principal destino de las peregrinaciones cristianas. Las que partían de los países occidentales son hoy bien conocidas debido a la considerable abundancia de relatos de peregrinos. Sin embargo, por razones geográficas, políticas y lingüísticas son poco conocidas las que realizaban a Tierra Santa los cristianos etíopes durante la Edad Media y los primeros tiempos modernos. Por eso mismo se debe conceder una importancia excepcional al relato de Francisco Álvarez que se divulgó por Europa sobre la fortuna de dos peregrinaciones que se dirigían a Jerusalén desde el país del Preste Juan. Dicho relato es un testimonio incomparable de las tensiones políticas, militares y religiosas que se produjeron en el entorno del mar Rojo a principios del siglo XVI

    Improved production of succinic acid from Basfia succiniciproducens growing on A-donax and process evaluation through material flow analysis

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    BackgroundDue to its wide range of applications in the food, pharmaceutical and chemical fields, microbial synthesis of succinic acid is receiving growing attention, generating already relevant industrial results, as well as fueling constant research for improvements. In order to develop a sustainable process, a special focus is now set on the exploitation and conversion of lignocellulosic biomasses into platform chemicals.ResultsIn the present work we used Basfia succiniciproducens BPP7 in separated hydrolysis and fermentation experiments with Arundo donax as starting material. Fed-batch strategies showed a maximal production of about 37g/L of succinic acid after 43h of growth and a productivity of 0.9g/Lh on the pilot scale. Global mass balance calculations demonstrated a hydrolysis and fermentation efficiency of about 75%. Moreover, the application of a material flow analysis showed the obtainment of 88.5 and 52 % of succinic acid, per kg of virgin biomass and on the total generated output, respectively.ConclusionsThe use of fed-batch strategies for the growth of B. succiniciproducens on A. donax improved the titer and productivity of succinic acid on pre-pilot scale. Process evaluation through material flow analysis showed successful results and predicted a yield of succinic acid of about 30% in a fed-batch process that uses A. donax as only carbon source also in the feed. Preliminary considerations on the possibility to achieve an energetic valorization of the residual solid coming from the fermentation process were also carried out
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