Versión española abreviada del cuestionario de ansiedad relacionada con el embarazo

The aim of this study is to obtain a Spanish brief version of the Pregnancy Related Anxiety Questionnaire and analyse its psychometric properties. A longitudinal study was carried out on a sample of 569 Spanish pregnant women with normal risk status. Participants were assessed in the first, second, and third trimesters of pregnancy by using a socio-demographic and obstetric-gynaecological questionnaire, the PRAQ-55, the Edinburgh Postnatal Depression Scale, and the State-Trait Anxiety Inventory. PRAQ-55 items with factorial loads > .50 were selected resulting in a final scale of 20 items. A cut-off point ≥ 67 (85th percentile) was used to identify women with high pregnancy-specific anxiety. The findings revealed that PRAQ-20 can be considered a useful screening tool in clinical practice to assess pregnancy-related anxiety in both nulliparous and multiparous pregnant womenEl objetivo de este estudio es obtener una versión breve en español del Cuestionario de Ansiedad Relacionada con el Embarazo y analizar sus propiedades psicométricas. Se realizó un estudio longitudinal en una muestra de 569 mujeres embarazadas españolas con un embarazo de riesgo normal. Se evaluó a las participantes en el primer, segundo y tercer trimestre de embarazo utilizando un cuestionario sociodemográfico y obstétrico-ginecológico, el PRAQ-55, la Escala de Depresión Postparto de Edimburgo y el Inventario de Ansiedad de Estado-Rasgo. Se seleccionaron los ítems de la PRAQ-55 con cargas factoriales > .50, lo que dio como resultado una escala final de 20 ítems. Se utilizó como punto de corte 67 (percentil 85) para identificar a aquellas mujeres con elevada ansiedad específica del embarazo. Los resultados mostraron que el PRAQ-20 puede considerarse una herramienta de cribado útil en la práctica clínica para evaluar la ansiedad relacionada con el embarazo tanto en mujeres embarazadas nulíparas como multíparasS

Prevalence of Depression during Pregnancy in Spanish Women: Trajectory and Risk Factors in Each Trimester

The aims of this research were to determine the trajectories of probable depression and major depression during pregnancy and to identify the associated and predictor variables (sociodemographic, pregnancy-related, and psychological) for both conditions in each trimester of pregnancy. A longitudinal study was carried out with 569 pregnant Spanish women who were assessed in the first, second, and third trimesters of pregnancy. Depression was assessed using the Edinburgh Postnatal Depression Scale and a clinical interview. Measures of anxiety and stress were also included. The prevalence of probable depression in the first, second, and third trimesters was 23.4%, 17.0%, and 21.4%, respectively, and that of major depression was 5.1%, 4.0%, and 4.7%. Thus, the prevalence of both conditions was the highest in the first and third trimesters. The trajectories of probable depression and major depression followed the same pattern throughout pregnancy. All of the psychological variables studied were associated with both conditions in all three trimesters, with perceived stress being a predictor at all times. The association between the other variables and both conditions of depression was similar. Two exceptions stand out: having had previous miscarriages, which was only associated with probable depression and was also a predictor, in the first trimester; and complications during pregnancy, which was only associated with probable and major depression in the third trimester. These findings should be taken into account in routine pregnancy follow-ups, and necessary interventions should be started in the first trimester.S

Yogur desnatado con transglutaminasa microbiana: evaluación de la aceptación del consumidor

The decrease in the fat content of yoghurt causes sensory modifications. Microbial transglutaminase (TG) has been proposed as an alternative for reducing the problems caused by the fat reduction. This work deals with the evaluation of the sensory profile, acceptance and preferences of skim yoghurt produced with TG at pilot scale. A group of 124 consumers of yoghurts were randomly selected. A lower firmness has been observed in yoghurt without TG (NoTG). TG Yoghurt has shown a lower whey odor and less acid taste than NoTG yoghurt. Free whey was not observed in the TG yoghurt. Despite of those differences, consumers only observed minor textural differences. In terms of overall acceptance and preference, no statistically significant differences were observed. The use of TG avoids the addition of milk protein or other texture additives into the yoghurt, decreasing production cost with the same overall acceptance and preference by consumers.La disminución del contenido graso del yogur provoca modificaciones sensoriales. La transglutami- nasa microbiana (TG) se ha propuesto como una alternativa para reducir los problemas causados por la reducción de grasa. Este trabajo trata sobre la evaluación del perfil sensorial, la aceptación y la preferencia del yogur desnatado producido con TG en una planta piloto. Un grupo de 124 consumidores de yogures fueron seleccionados al azar. Una menor firmeza se observó en el yogur sin TG (NoTG). EL yogur con TG mostró menor olor a suero, menor sabor ácido que el yogur NoTG. No se observó suero en el yogur con TG. A pesar de esas diferencias, los consumidores solo observaron pequeñas diferencias de textura. En términos de aceptación global y preferencia, no se observaron diferencias estadísticamente significativas. El uso de TG evita la adición de proteínas de la leche u otros aditivos para mejorar la textura del yogur, lo que reduce los costes de producción manteniéndose la aceptación y preferencia por parte de los consumidores.This research was supported by MICINN (Spain) [Project No. RTC2014- 1835-2] and Consellería de Cultura, Educación e Ordenación Universitaria, Xunta de Galicia (ES) [Project No. ED431B 2016/009]S

Sensory descriptive analysis and hedonic consumer test for Galician type breads

Bread consumption has declined in recent years due to the loss of its sensory quality. To identify the key sensory attributes for the consumer, in this study will provide to the bakery industry with a powerful tool to design products adapted to the consumer preferences will be provided to the bakery industry. For identifying the key attributes 7 Galician breads were evaluated by a trained panel using 22 attributes using the Quantitative Descriptive Analysis. In addition, a sensory acceptance test carried out by 97 consumers provided hedonic evaluations. The results of the joint analysis (trained panel and consumers) demonstrated that the loaves with the moistest bread crumb, with a predominance of large cells, and an alveolation with non-uniform distribution were the ones that presented the greatest acceptance. The use of an artisanal production process (sourdough and long fermentation time) and the incorporation into the recipe of indigenous flour (around 40%) improved the acceptance of the Galician breadS

Rapid decrease in titer and breadth of neutralizing anti-HCV antibodies in HIV/HCV-coinfected patients who achieved SVR

The main targets for neutralizing anti-hepatitis C virus (HCV) antibodies (HCV-nAbs) are the E1 and E2 envelope glycoproteins. We have studied the characteristics of HCV-nAbs through a retrospective study involving 29 HIV/HCV-coinfected patients who achieved sustained virological response (SVR) with pegIFNα+ribavirin anti-HCV therapy. Plasma samples at baseline and week 24 after SVR were used to perform neutralization assays against fve JFH1-based HCV recombinant viruses coding for E1 and E2 from genotypes 1a (H77), 1b (J4), 2a (JFH1), 3a (S52) and 4a (ED43). At baseline, the majority of plasma samples neutralized 1a, 1b, 2a, and 4a, but not 3a, genotypes. Twenty-four weeks following SVR, most neutralizing titers declined substantially. Furthermore, titers against 3a and 2a were not detected in many patients. Plasma samples with high HCV-nAb titers neutralized all genotypes, and the highest titers at the starting point correlated with the highest titers at week 24 after SVR. In conclusion, high titers of broad-spectrum HCV-nAbs were detected in HIV/HCV-coinfected individuals, however, those titers declined soon after SVRThis study was supported by grants from Instituto de Salud Carlos III (ISCIII; grant numbers PI14/01094 and PI17/00657 to JB, PI17/00903 to JGG, PI14CIII/00011 and PI17CIII/00003 to SR) and Ministerio de Sanidad, Servicios Sociales e Igualdad (grant number EC11-241). Te study was also funded by the RD16CIII/0002/0002, RD16/0025/0018, and RD16/0025/0017 projects as part of the Plan Nacional R+D+I and co-funded by ISCIII- Subdirección General de Evaluación and the Fondo Europeo de Desarrollo Regional (FEDER

Cuidados en el puerperio durante la Crisis sanitaria por CoVid-19

Introducción: la infección por el nuevo coronavirus COVID-19, es actualmente una emergencia de salud pública internacional y ha sido declarada pandemia por la OMS. Aún se desconocen ciertos datos sobre su etiopatogenia, surgiendo la necesidad de analizar la influencia de la enfermedad por coronavirus durante la etapa puerperal y sus conse-cuencias. Objetivo: sintetizar el conocimiento y las últimas recomendaciones disponibles acerca de los cuidados específicos durante el periodo del puerperio, en relación con la crisis sanitaria por COVID-19. Metodología: se llevó a cabo una búsqueda sistemática en la literatura científica para localizar los documentos de evidencia científica disponibles en las principales bases de datos referenciales: Pubmed, Biblioteca Cochrane y Science Direct. Resultados: la lactancia materna aporta numerosos beneficios al recién nacido, entre ellos, la protección frente a infecciones respiratorias como el coronavirus. Si el estado materno y neonatal lo permite, se recomienda promover la lactancia materna durante el periodo de riesgo infeccioso. La SEGO y la SETH recomiendan la administra-ción de heparina de bajo peso molecular a dosis profilácticas para evitar la enfermedad tromboembólica. La evidencia actual indica que el riesgo de transmisión a través de la lactancia materna al recién nacido es muy poco probable. Discusión/conclusiones: la limitación principal fue la escasez de literatura científica sobre el COVID-19 en relación con el periodo puerperal. Es fundamental que cualquier puérpera con una infección por COVID-19 y su recién nacido sean valorados de manera individualizada, precozmente y evaluada por un equipo multidisciplinar para prevenir resultados adversosIntroduction: the new coronavirus COVID-19 infection is currently an international pu-blic health emergency and it has been declared a pandemic by the WHO. Certain data about its etiopathogenesis is still unknown, arising the need to analyse the influence of coronavirus disease during the puerperal stage and its consequences. Objective:to synthesize the knowledge and the latest available recommendations about specific care during puerperium period, related to the health crisis due to COVID-19. Methodo-logy: a systematic search was carried out in the scientific literature in order to locate the scientific evidence documents available in the main reference databases: PubMed, Cochrane Library and Science Direct. Results: breastfeeding brings many benefits to newborns, including protection against respiratory infections, such as coronavirus. If maternal and neonatal status allows it, it is recommended promoting breastfeeding during the infectious risk period. Both SEGO and SETH recommend the administration of low molecular weight heparin at prophylactic doses in order to avoid thromboembolic disease. Discussion/conclusions: the main limitation was the paucity of scientific lite-rature about COVID-19 in relation to puerperal period. It is essential that any puerperal woman with COVID-19 infection and her newborn are assessed individually, early and evaluated by a multidisciplinary team to prevent adverse outcome

Los montes submarinos en los márgenes continentales de Iberia

Seamounts are first-order morphological elements on continental margins and in oceanic domains, which have been extensively researched over recent decades in all branches of oceanography. These features favour the development of several geological processes, and their study gives us a better understanding of their geological and morphological domains. The seamounts around Iberia are numerous and provide excellent examples of the geodiversity of these morphological elements. Here we present a compilation of 15 seamounts around the Iberian Peninsula. These seamounts have different origins related to the geodynamic evolution (volcanism, extensional or compressive tectonics, and diapirism) of the domains where they are located. The current configuration of their relief has been influenced by Neogene-Quaternary tectonics. Their positioning controls the current morpho-sedimentary processes in the basins and on the margins, and highlights the fact that downslope processes on seamount flanks (mass flows, turbidite flows, and landslides) and processes parallel to seamounts (contouritic currents) correspond to the major geological features they are associated with them. Biogenic structures commonly develop on the tops of seamounts where occasionally isolated shelves form that have carbonate-dominated sedimentation.Los montes submarinos son rasgos morfológicos singulares, cuyo estudio tiene gran relevancia desde el punto de vista de las distintas ramas de la oceanografía. Su presencia favorece el desarrollo de diferentes procesos geológicos y proporciona un mejor conocimiento de los dominios geológicos y morfológicos en los que se encuentran. En el entorno de Iberia, los montes submarinos tienen una amplia representación y tipología. En este trabajo, se presenta una recopilación geológica de 15 montes submarinos (ocho en el Mar Mediterráneo y siete en el Océano Atlántico) de los márgenes continentales de Iberia y en el dominio Oceánico Atlántico, utilizándose levantamientos batimétricos y geofísicos. El origen de estos montes es muy diferente y está relacionado con la evolución geodinámica del dominio geológico en el que aparecen (volcanismo, tectónica extensional o compresional y diapirismo). La configuración actual del relieve ha sido controlada por la actividad tectónica en el Neógeno-Cuaternario. Su presencia controla el desarrollo de los procesos morfosedimentarios recientes de márgenes y cuencas. Los principales procesos sedimentarios asociados a estos montes se relacionan con procesos longitudinales (flujos en masa, flujos turbidíticos, deslizamientos) y transversales a dichos montes (corrientes de contorno). Además es frecuente en ellos el desarrollo de cuerpos biogénicos sobre sus cimas e incluso de plataformas con sedimentación carbonatada. Los montes submarinos de Iberia muestran una gran geodiversidad y constituyen un elemento morfológico de primer orden para comprender los procesos geológicos que tienen lugar en sus márgenes continentales y dominios oceánicos adyacentes.Versión del editor0,000

Expressed sequence tags (ESTs) from immune tissues of turbot (Scophthalmus maximus) challenged with pathogens

Background: The turbot (Scophthalmus maximus; Scophthalmidae; Pleuronectiformes) is a flatfish species of great relevance for marine aquaculture in Europe. In contrast to other cultured flatfish, very few genomic resources are available in this species. Aeromonas salmonicida and Philasterides dicentrarchi are two pathogens that affect turbot culture causing serious economic losses to the turbot industry. Little is known about the molecular mechanisms for disease resistance and hostpathogen interactions in this species. In this work, thousands of ESTs for functional genomic studies and potential markers linked to ESTs for mapping (microsatellites and single nucleotide polymorphisms (SNPs)) are provided. This information enabled us to obtain a preliminary view of regulated genes in response to these pathogens and it constitutes the basis for subsequent and more accurate microarray analysis. Results: A total of 12584 cDNAs partially sequenced from three different cDNA libraries of turbot (Scophthalmus maximus) infected with Aeromonas salmonicida, Philasterides dicentrarchi and from healthy fish were analyzed. Three immune-relevant tissues (liver, spleen and head kidney) were sampled at several time points in the infection process for library construction. The sequences were processed into 9256 high-quality sequences, which constituted the source for the turbot EST database. Clustering and assembly of these sequences, revealed 3482 different putative transcripts, 1073 contigs and 2409 singletons. BLAST searches with public databases detected significant similarity (e-value ≤ 1e-5) in 1766 (50.7%) sequences and 816 of them (23.4%) could be functionally annotated. Two hundred three of these genes (24.9%), encoding for defence/immunerelated proteins, were mostly identified for the first time in turbot. Some ESTs showed significant differences in the number of transcripts when comparing the three libraries, suggesting regulation in response to these pathogens. A total of 191 microsatellites, with 104 having sufficient flanking sequences for primer design, and 1158 putative SNPs were identified from these EST resources in turbot. Conclusion: A collection of 9256 high-quality ESTs was generated representing 3482 unique turbot sequences. A large proportion of defence/immune-related genes were identified, many of them regulated in response to specific pathogens. Putative microsatellites and SNPs were identified. These genome resources constitute the basis to develop a microarray for functional genomics studies and marker validation for genetic linkage and QTL analysis in turbot.This study was supported by a Consellería de Pesca e Asuntos Marítimos and the Dirección Xeral de I+D – Xunta de Galicia project (2004/CP480)S

Influencia de la tectónica cuaternaria sobre la morfología del talud continental de la región de Adra (Mar de Alborán septentrional)

El análisis de un mosaico batimétrico y de perfiles sísmicos de alta resolución ha permitido definir la geomorfología tectónica del Margen de Adra, sector norte del Mar de Alborán. Se han identificado cuatro tipos morfológicos relacionados con estructuras tectónicas: (i) Crestas longitudinales (N50-70); (ii) Escarpes lineales (N30, N55, N130, N165, N-S); (iii) Depresiones tectónicas (N130, N165, N-S), y (iv) Líneas de cambio de la pendiente (N130). Este esquema morfoestructural se relaciona con un cabalgamiento ciego (NO-SE) en el sector NO, y en el oriental con la falla de desgarre siniestra de La Serrata (NE-SO). Entre estas dos estructuras se ha desarrollado un sistema de fallas de desgarre diestras (NO-SE) que incluye a la Falla de Adra, y un corredor NNE-SSO constituido por fallas secundarias NNO-SSE. Además se han observado fallas inversas menores N-S que pueden ser consecuencia de la interferencia de los principales sistemas de fallas de la región con el Banco de Chella.The analysis of multibeam bathymetric data and high resolution seismic profiles has allowed us to define the tectonic geomorphology of the Adra margin, northern Alboran Sea. Four geomorphic tectonic-related structures have been analyzed: (i) Longitudinal ridges (N50-70); (ii) Linear scarps (N30, N55, N130, N165, N-S); (iii) Tectonic depressions (N130, N165, N-S), and (iv) Lines of changes in the slope gradient (N130). In the northwestern sector morphostructure is related to a blind thrust (NE-SW), which folds Quaternary units, and in the eastern sector is linked to the NE-SW sinistral strike slip fault of La Serrata (NE-SW). Between these two structures, a NW-SE dextral strike-slip fault system, including the Adra Fault, and a NNE-SSW highly deformed corridor constituted by secondary NNW-SSE faults have been developed. Minor high angle N-S reverse faults can be related to secondary deformation features, due mainly to the interference of Chella Bank and the regional main fault systems.Postprin