16 research outputs found
Early maternal separation followed by later stressors leads to dysregulation of the HPA-axis and increases in hippocampal NGF and NT-3 levels in a rat model.
- Publication venue
- Publication date
- 01/01/2006
- Field of study
Early adverse life events, followed by subsequent stressors, appear to increase susceptibility for subsequent onset of psychiatric disorders in humans. The molecular mechanisms that underlie this phenomenon remain unclear, but dysregulation of the HPA axis and alterations in neurotrophic factors have been implicated. The present study investigated the effects in rodents of early maternal separation, followed by stress in adolescence and adulthood on later HPA-axis activity and hippocampal neurotrophin levels (brain-derived neurotrophic factor, nerve growth factor, and neurotrophin-3). Animals subjected to repeated stressors showed a significant decrease in basal ACTH (p < 0.05) and CORT (p < 0.05) levels when compared to controls, as well as significantly increased levels of NGF in the dorsal (p < 0.001) and ventral hippocampus (p < 0.01), and of NT-3 in the dorsal hippocampus (p < 0.01). Dysregulation of the HPA axis after multiple stressors is consistent with previous preclinical and clinical work. Given that neurotrophins are important in neuronal survival and plasticity, it is possible to speculate that their elevation reflects a compensatory mechanism.Articl
Preclinical pharmacokinetic analysis of NOV-002, a glutathione disulfide mimetic
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
SNObase, a database for S-nitrosation modification
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
N-Acetylcysteine Inhibits Kynurenine Aminotransferase II
- Author
- Alexander
- Altuntas
- Bavarsad Shahripour
- Berk
- Bortz
- Breier
- Bridges
- Cao
- Chan
- Chess
- Conus
- Csontos
- de Bartolomeis
- Dean
- DeAngeli
- Deepmala
- Do
- Dodd
- Erhardt
- Erhardt
- Erhardt
- Farr
- Gawryluk
- Goff
- Green
- Guidetti
- Guidetti
- Hedges
- Hertz
- Heyes
- J.D. Uys
- K.V. Sathyasaikumar
- Keefe
- Klauser
- Konradsson-Geuken
- Kozak
- Kranich
- L.S. Pidugu
- Lavoie
- Lewis
- Linderholm
- Lowry
- McBean
- McQueen
- Miller
- Nikiforuk
- Olive
- Ooi
- Otte
- Oxenkrug
- Pershing
- Plitman
- Pocivavsek
- Potter
- R. Schwarcz
- Rapado-Castro
- Retsa
- Robbins
- Rossi
- Rushworth
- Samuni
- Sathyasaikumar
- Schwarcz
- Schwarcz
- Schwarcz
- Sepehrmanesh
- Sheffner
- Shepard
- Shibata
- Skvarc
- Steullet
- Swartz
- T. Blanco-Ayala
- Timofeeva
- Tsai
- Turski
- Uys
- V. Pérez-de-la-Cruz
- Wonodi
- Wonodi
- Xiong
- Yang
- Yolland
- Yolland
- Zmarowski
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Zukunftsstrategien für die Entdeckung neuer Antidepressiva
- Author
- A. Bilkei-Gorzo
- A. Gesing
- A. Steiger
- A. Vezzani
- A.G. Williams
- A.J. Rush
- A.W. Zobel
- B. Khakh
- C. Crochemore
- C. DeBattista
- C. Heim
- C. Mirescu
- C.A. Stockmeier
- C.J. Phiel
- C.J. Swanson
- D. Refojo
- D.A. Berry
- D.J. David
- D.L. Gerhold
- E. Binder
- E.R. Kloet de
- F. Holsboer
- F. Holsboer
- G. Griebel
- G. Kempermann
- G. Rajkowska
- H. Eldar-Finkelman
- H. Jahn
- H. Kitano
- H. Murck
- I.C. Weaver
- J. Angst
- J. Greef van der
- J. Kraft
- J. O’Donnell ó
- J. Temsamani
- J.A. Blendy
- J.D. Uys
- J.E. Malberg
- J.M. Reul
- J.P. Mayer
- J.P. Redrobe
- K. Fujimaki
- L. Santarelli
- M. Heilig
- M. Ising
- M. Ising
- M. Keller
- M. Roy
- M.A. Saunders
- M.B. Müller
- M.B. Müller
- M.E. Keck
- M.F. Fraga
- M.S. Kramer
- N.M. Tsankova
- O. Kaidanovich-Beilin
- R. Alonso
- R. Landgraf
- R. Wehrle
- R.D. Bhardwaj
- R.D. Palmiter
- S. Krömer
- S. Lucae
- S.C. Ceide
- T. Kato
- T. Nickel
- T. Shimazaki
- W.W. Fleischhacker
- X. Lu
- X. Lu
- Y.I. Sheline
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2008
- Field of study
Tubular Structures
- Author
- A. Lamas
- A. Mordecai
- A. Osyczka
- A. Osyczka
- A. Snyman J
- A. Snyman J
- A. Snyman J
- A. Snyman J
- A. Spagnoli
- A. Spagnoli
- A. Spagnoli
- A.A. Groenwold
- A.H. Buchanan
- A.H. Buchanan
- A.L. Telojan
- A.V. Fiacco
- C.J.P. Rodrigues
- C.P. Ellinas
- C.T.F. Ross
- C.T.F. Ross
- D. Dasgupta
- D. Dutta
- D. Dutta
- D. Lungu
- D. Lungu
- D.A. Spera
- D.E. Goldberg
- D.M. Himmelblau
- D.M. Himmelblau
- E. Pettersen
- E.S. Kameshki
- F. Orbán
- G. Cox
- G. Cox
- G. Glushkov
- G. Horváth
- G. Y. Grondin
- G.I.N Rozvany
- H. A. Schade
- H. Ge
- H.H. Rosenbrock
- H.H. Rosenbrock
- H.J.M. Bodt
- HR Evans
- I Mikami
- I. Lavassas
- I. Tímár
- J A Snyman
- J A Snyman
- J A Snyman
- J A Snyman
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Haroutel
- J. K. Paik
- J. Koski
- J. Rondal
- J. Singer
- J. Tian
- J. Wardenier
- J.A. Snyman
- J.A. Snyman
- J.A. Snyman
- J.A. Snyman
- J.A. Snyman
- J.D. Farmer
- J.K. Paik
- J.L. Zhou
- J.N. Siddall
- J.N. Siddall
- J.P.C. Rodrigues
- JR. Birchfield
- K. Azuma
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Miura
- L.M.C. Simões
- L.M.C. Simões
- L.M.C. Simões
- M. Dorigo
- M. Fujikubo
- M. Ifrim
- M. Ifrim
- M. Iványi
- M. Steenhuis
- M.J. Box
- M.J. Box
- M.K. Chryssanthopoulos
- M.M. Millonas
- N. Bazeos
- N.S. Moskalev
- NE Shanmugam
- O. Steinhardt
- P. Sahmel
- P.E. Uys
- R. Storn
- S. Kmet'
- S.L. Lee
- S.P. Timoshenko
- S.P. Timoshenko
- S.P. Timoshenko
- S.P. Timoshenko
- S.S. Rao
- S.S. Rao
- S.S. Rao
- S.W. Golomb
- Shen Hui-shen
- T. Liszkai
- T.R. Kay
- T.R. Kay
- Ts. Usami
- U. Klansek
- U. Klansek
- V. Pareto
- V.K. Kachurin
- V.K. Koumousis
- W.M.K. Tizani
- X.L. Zhao
- Y. Fan
- Y. Kurobane
- Y. Kurobane
- Y.A. Al-Salloum
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2008
- Field of study
Welded Stiffened Cylindrical and Conical Shells
- Author
- A. Lamas
- A. Mordecai
- A. Osyczka
- A. Osyczka
- A. Snyman J
- A. Snyman J
- A. Snyman J
- A. Snyman J
- A. Spagnoli
- A. Spagnoli
- A. Spagnoli
- A.A. Groenwold
- A.H. Buchanan
- A.H. Buchanan
- A.L. Telojan
- A.V. Fiacco
- C.J.P. Rodrigues
- C.P. Ellinas
- C.T.F. Ross
- C.T.F. Ross
- D. Dasgupta
- D. Dutta
- D. Dutta
- D. Lungu
- D. Lungu
- D.A. Spera
- D.E. Goldberg
- D.M. Himmelblau
- D.M. Himmelblau
- E. Pettersen
- E.S. Kameshki
- F. Orbán
- G. Cox
- G. Cox
- G. Glushkov
- G. Horváth
- G. Y. Grondin
- G.I.N Rozvany
- H. A. Schade
- H. Ge
- H.H. Rosenbrock
- H.H. Rosenbrock
- H.J.M. Bodt
- HR Evans
- I Mikami
- I. Lavassas
- I. Tímár
- J A Snyman
- J A Snyman
- J A Snyman
- J A Snyman
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Haroutel
- J. K. Paik
- J. Koski
- J. Rondal
- J. Singer
- J. Tian
- J. Wardenier
- J.A. Snyman
- J.A. Snyman
- J.A. Snyman
- J.A. Snyman
- J.A. Snyman
- J.D. Farmer
- J.K. Paik
- J.L. Zhou
- J.N. Siddall
- J.N. Siddall
- J.P.C. Rodrigues
- JR. Birchfield
- K. Azuma
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Miura
- L.M.C. Simões
- L.M.C. Simões
- L.M.C. Simões
- M. Dorigo
- M. Fujikubo
- M. Ifrim
- M. Ifrim
- M. Iványi
- M. Steenhuis
- M.J. Box
- M.J. Box
- M.K. Chryssanthopoulos
- M.M. Millonas
- N. Bazeos
- N.S. Moskalev
- NE Shanmugam
- O. Steinhardt
- P. Sahmel
- P.E. Uys
- R. Storn
- S. Kmet'
- S.L. Lee
- S.P. Timoshenko
- S.P. Timoshenko
- S.P. Timoshenko
- S.P. Timoshenko
- S.S. Rao
- S.S. Rao
- S.S. Rao
- S.W. Golomb
- Shen Hui-shen
- T. Liszkai
- T.R. Kay
- T.R. Kay
- Ts. Usami
- U. Klansek
- U. Klansek
- V. Pareto
- V.K. Kachurin
- V.K. Koumousis
- W.M.K. Tizani
- X.L. Zhao
- Y. Fan
- Y. Kurobane
- Y. Kurobane
- Y.A. Al-Salloum
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2008
- Field of study
Cost Calculations
- Author
- A. Lamas
- A. Mordecai
- A. Osyczka
- A. Osyczka
- A. Snyman J
- A. Snyman J
- A. Snyman J
- A. Snyman J
- A. Spagnoli
- A. Spagnoli
- A. Spagnoli
- A.A. Groenwold
- A.H. Buchanan
- A.H. Buchanan
- A.L. Telojan
- A.V. Fiacco
- C.J.P. Rodrigues
- C.P. Ellinas
- C.T.F. Ross
- C.T.F. Ross
- D. Dasgupta
- D. Dutta
- D. Dutta
- D. Lungu
- D. Lungu
- D.A. Spera
- D.E. Goldberg
- D.M. Himmelblau
- D.M. Himmelblau
- E. Pettersen
- E.S. Kameshki
- F. Orbán
- G. Cox
- G. Cox
- G. Glushkov
- G. Horváth
- G. Y. Grondin
- G.I.N Rozvany
- H. A. Schade
- H. Ge
- H.H. Rosenbrock
- H.H. Rosenbrock
- H.J.M. Bodt
- HR Evans
- I Mikami
- I. Lavassas
- I. Tímár
- J A Snyman
- J A Snyman
- J A Snyman
- J A Snyman
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Haroutel
- J. K. Paik
- J. Koski
- J. Rondal
- J. Singer
- J. Tian
- J. Wardenier
- J.A. Snyman
- J.A. Snyman
- J.A. Snyman
- J.A. Snyman
- J.A. Snyman
- J.D. Farmer
- J.K. Paik
- J.L. Zhou
- J.N. Siddall
- J.N. Siddall
- J.P.C. Rodrigues
- JR. Birchfield
- K. Azuma
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Miura
- L.M.C. Simões
- L.M.C. Simões
- L.M.C. Simões
- M. Dorigo
- M. Fujikubo
- M. Ifrim
- M. Ifrim
- M. Iványi
- M. Steenhuis
- M.J. Box
- M.J. Box
- M.K. Chryssanthopoulos
- M.M. Millonas
- N. Bazeos
- N.S. Moskalev
- NE Shanmugam
- O. Steinhardt
- P. Sahmel
- P.E. Uys
- R. Storn
- S. Kmet'
- S.L. Lee
- S.P. Timoshenko
- S.P. Timoshenko
- S.P. Timoshenko
- S.P. Timoshenko
- S.S. Rao
- S.S. Rao
- S.S. Rao
- S.W. Golomb
- Shen Hui-shen
- T. Liszkai
- T.R. Kay
- T.R. Kay
- Ts. Usami
- U. Klansek
- U. Klansek
- V. Pareto
- V.K. Kachurin
- V.K. Koumousis
- W.M.K. Tizani
- X.L. Zhao
- Y. Fan
- Y. Kurobane
- Y. Kurobane
- Y.A. Al-Salloum
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2008
- Field of study
References
- Author
- A. Lamas
- A. Mordecai
- A. Osyczka
- A. Osyczka
- A. Snyman J
- A. Snyman J
- A. Snyman J
- A. Snyman J
- A. Spagnoli
- A. Spagnoli
- A. Spagnoli
- A.A. Groenwold
- A.H. Buchanan
- A.H. Buchanan
- A.L. Telojan
- A.V. Fiacco
- C.J.P. Rodrigues
- C.P. Ellinas
- C.T.F. Ross
- C.T.F. Ross
- D. Dasgupta
- D. Dutta
- D. Dutta
- D. Lungu
- D. Lungu
- D.A. Spera
- D.E. Goldberg
- D.M. Himmelblau
- D.M. Himmelblau
- E. Pettersen
- E.S. Kameshki
- F. Orbán
- G. Cox
- G. Cox
- G. Glushkov
- G. Horváth
- G. Y. Grondin
- G.I.N Rozvany
- H. A. Schade
- H. Ge
- H.H. Rosenbrock
- H.H. Rosenbrock
- H.J.M. Bodt
- HR Evans
- I Mikami
- I. Lavassas
- I. Tímár
- J A Snyman
- J A Snyman
- J A Snyman
- J A Snyman
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Haroutel
- J. K. Paik
- J. Koski
- J. Rondal
- J. Singer
- J. Tian
- J. Wardenier
- J.A. Snyman
- J.A. Snyman
- J.A. Snyman
- J.A. Snyman
- J.A. Snyman
- J.D. Farmer
- J.K. Paik
- J.L. Zhou
- J.N. Siddall
- J.N. Siddall
- J.P.C. Rodrigues
- JR. Birchfield
- K. Azuma
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Miura
- L.M.C. Simões
- L.M.C. Simões
- L.M.C. Simões
- M. Dorigo
- M. Fujikubo
- M. Ifrim
- M. Ifrim
- M. Iványi
- M. Steenhuis
- M.J. Box
- M.J. Box
- M.K. Chryssanthopoulos
- M.M. Millonas
- N. Bazeos
- N.S. Moskalev
- NE Shanmugam
- O. Steinhardt
- P. Sahmel
- P.E. Uys
- R. Storn
- S. Kmet'
- S.L. Lee
- S.P. Timoshenko
- S.P. Timoshenko
- S.P. Timoshenko
- S.P. Timoshenko
- S.S. Rao
- S.S. Rao
- S.S. Rao
- S.W. Golomb
- Shen Hui-shen
- T. Liszkai
- T.R. Kay
- T.R. Kay
- Ts. Usami
- U. Klansek
- U. Klansek
- V. Pareto
- V.K. Kachurin
- V.K. Koumousis
- W.M.K. Tizani
- X.L. Zhao
- Y. Fan
- Y. Kurobane
- Y. Kurobane
- Y.A. Al-Salloum
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2008
- Field of study
Frames
- Author
- A. Lamas
- A. Mordecai
- A. Osyczka
- A. Osyczka
- A. Snyman J
- A. Snyman J
- A. Snyman J
- A. Snyman J
- A. Spagnoli
- A. Spagnoli
- A. Spagnoli
- A.A. Groenwold
- A.H. Buchanan
- A.H. Buchanan
- A.L. Telojan
- A.V. Fiacco
- C.J.P. Rodrigues
- C.P. Ellinas
- C.T.F. Ross
- C.T.F. Ross
- D. Dasgupta
- D. Dutta
- D. Dutta
- D. Lungu
- D. Lungu
- D.A. Spera
- D.E. Goldberg
- D.M. Himmelblau
- D.M. Himmelblau
- E. Pettersen
- E.S. Kameshki
- F. Orbán
- G. Cox
- G. Cox
- G. Glushkov
- G. Horváth
- G. Y. Grondin
- G.I.N Rozvany
- H. A. Schade
- H. Ge
- H.H. Rosenbrock
- H.H. Rosenbrock
- H.J.M. Bodt
- HR Evans
- I Mikami
- I. Lavassas
- I. Tímár
- J A Snyman
- J A Snyman
- J A Snyman
- J A Snyman
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Farkas
- J. Haroutel
- J. K. Paik
- J. Koski
- J. Rondal
- J. Singer
- J. Tian
- J. Wardenier
- J.A. Snyman
- J.A. Snyman
- J.A. Snyman
- J.A. Snyman
- J.A. Snyman
- J.D. Farmer
- J.K. Paik
- J.L. Zhou
- J.N. Siddall
- J.N. Siddall
- J.P.C. Rodrigues
- JR. Birchfield
- K. Azuma
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Jármai
- K. Miura
- L.M.C. Simões
- L.M.C. Simões
- L.M.C. Simões
- M. Dorigo
- M. Fujikubo
- M. Ifrim
- M. Ifrim
- M. Iványi
- M. Steenhuis
- M.J. Box
- M.J. Box
- M.K. Chryssanthopoulos
- M.M. Millonas
- N. Bazeos
- N.S. Moskalev
- NE Shanmugam
- O. Steinhardt
- P. Sahmel
- P.E. Uys
- R. Storn
- S. Kmet'
- S.L. Lee
- S.P. Timoshenko
- S.P. Timoshenko
- S.P. Timoshenko
- S.P. Timoshenko
- S.S. Rao
- S.S. Rao
- S.S. Rao
- S.W. Golomb
- Shen Hui-shen
- T. Liszkai
- T.R. Kay
- T.R. Kay
- Ts. Usami
- U. Klansek
- U. Klansek
- V. Pareto
- V.K. Kachurin
- V.K. Koumousis
- W.M.K. Tizani
- X.L. Zhao
- Y. Fan
- Y. Kurobane
- Y. Kurobane
- Y.A. Al-Salloum
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2008
- Field of study