An Intelligent Monitoring System of Vehicles on Highway Traffic

Vehicle speed monitoring and management of highways is the critical problem of the road in this modern age of growing technology and population. A poor management results in frequent traffic jam, traffic rules violation and fatal road accidents. Using traditional techniques of RADAR, LIDAR and LASAR to address this problem is time-consuming, expensive and tedious. This paper presents an efficient framework to produce a simple, cost efficient and intelligent system for vehicle speed monitoring. The proposed method uses an HD (High Definition) camera mounted on the road side either on a pole or on a traffic signal for recording video frames. On the basis of these frames, a vehicle can be tracked by using radius growing method, and its speed can be calculated by calculating vehicle mask and its displacement in consecutive frames. The method uses pattern recognition, digital image processing and mathematical techniques for vehicle detection, tracking and speed calculation. The validity of the proposed model is proved by testing it on different highways.Comment: 5 page

Stentless pyeloplasty for ureteropelvic junction obstruction in children

Introduction Stenting after pyeloplasty is an established practice and helps in  ensuring a patent anastomosis until healing has completed. Stents, however, may cause complications such as infection and displacement and increase the cost of management; therefore, stentless pyeloplasty is now considered as feasible  alternative.Patients and methods From August 2008 to October 2010, we retrospectively analyzed the results of stentless surgery in patients with ureteropelvic junction  (UPJ) obstruction. In all, 42 patients with UPJ obstruction were managed. Nine patients who were treated conservatively, one who underwent nephrectomy, and one pyelostomy for pyonephrosis in solitary kidney were excluded. Age range at surgery was 14 days–12 years with a mean age of 12.7 months.Results There were 23 male patients and eight female patients with a male-to-female ratio of 3 : 1. Fourteen patients had left, 12 right, and five had bilateral UPJ obstruction. A total of 34 pyeloplasties were performed in 31 patients. Of the five patients with bilateral UPJ obstruction, three underwent bilateral pyeloplasty and remaining two underwent unilateral pyeloplasty with conservative management on the opposite sides. Two patients underwent laparoscopic pyeloplasties and32 pyeloplasties by open technique. Double J stent was placed at initial surgery in three patients and 31 stentless pyeloplasties were performed. The mean operative time was 75 min. The mean perinephric drain removal time was 2 days. None of the patients had persistent urinary leak. The mean hospital stay was 3.2 days. Reduction in anteroposterior diameter was noticed in 91% cases on 12 weeks  follow-up scan. Complications included persistent or increase in hydronephrosis in three (9%) patients. In all the three patients, cystoscopic stenting was attempted. In two patients, size 4 Fr double J stent was passed easily into the renal pelvis. Onepatient improved, whereas other still has a dilated pelvis with static anteroposterior diameter after removal of stent at 6 weeks; patient is kept on close surveillance on regular ultrasonography. Re-exploration was performed in one patient, which showed kinking at the anastomosis site. Pyeloplasty was revised and patient improved. Other complications included lumbar hernia in one patient, which improved at 6-month follow-up, and stitch granuloma in one patient, which improved after removal of residual stitch.Conclusion Stentless surgery for UPJ obstruction is a safe and feasible technique; it reduces the cost of surgery and avoids multiple procedures. Keywords: management, pyeloplasty, stentless, ureteropelvic junction obstruction

A Novel Homozygous Frameshift Variant in XYLT2 Causes Spondyloocular Syndrome in a Consanguineous Pakistani Family

We report on three new patients with spondyloocular syndrome (SOS) in a consanguineous Pakistani family. All three patients present progressive generalized osteoporosis, short stature, recurrent fractures, hearing loss and visual impairments. WES revealed a novel homozygous frameshift variant in exon 11 of XYLT2 (NG 012175.1, NP_071450.2) resulting in loss of evolutionary conserved amino acid sequences (840 - 865/865) at C -terminus p.R840fs*115. Sanger Sequencing confirmed the presence of the novel homozygous mutation in all three patients while the parents were heterozygous carriers of the mutation, in accordance with an autosomal recessive inheritance pattern. Only nine variants worldwide have previously been reported in XYLT2 in patients with SOS phenotype. These three patients with novel homozygous variant extend the genotypic and phenotypic spectrum of SOS.Peer reviewe

Physical Properties of Different Brands of Cement Manufactured in KPK, Pakistan: A Case Study

One of the key elements affecting structural concrete's strength and longevity is the cement's quality. In Pakistan, large amounts of cement are utilized in construction projects. This study appraised some physical properties of five brands of Portland cement bought from cement industries in KPK. Cement brands are investigated, including Cherat cement, Askary cement, Luckey cement, Kohat +, and Bestway cement. The composition of the cement has been recorded from the cement bags. Each initial setting time, normal consistency, final setting time, fineness, and compressive strength cement samples (collected as bags from the market) have been tested in the laboratory at three days, seven days, 14 days, and 28 days per ASTM standards. Amongst these various cement brands in KPK, we aim to investigate the best cement brands taking into consideration the above all physical test and then test these brands after three months. Taking time as a factor, the best cement quality is to be found. According to the fineness of cement, Cherat cement is found to be the best amongst all five brands of cement when tested initially, while lucky and Kohat were the least in fineness properties. Consistency tests were performed for all brands of fresh types of cement, and Cherat and Kohat have more consistency, while Askary has the least consistency. Initial and Final setting time tests were performed for all brands, and Cherat cement was found to have the more initial and final setting time, while Kohat and Askary had the least setting time. In the case of the compressive strength test, Cherat cement was found to be the greater strength, while lucky had the least compressive strength. For seven days curing. For 28 days curing Cherat cement was the best one having greater strength, while Askary had the least strength among all. All the cement brands were tested the same way after three months of age, which shows that all five brands crossed the ranges for each test. Still, it has been observed that the decrease in the fineness is small for Cherat compared to all other brands while in case of compressive strength, the decrease in Cherat is greater than all other brands

New furocarbazole alkaloids from Lonicera quinquelocularis

Two new furocarbazole alkaloids, 3-formyl-6,7-dimethoxy-furo[1,2]carbazole (1) and methyl-6,7-dimethoxy-furo[1,2]carbazole-3-carboxylate (2), along with two known carbazole alkaloids, 3-formyl-2-hydroxy-7-methoxycarbazole (3) and methyl 2,7-dimethoxycarbazole-3-carboxylate (4) were isolated from the ethyl acetate soluble fraction of Lonicera quinquelocularis. Their structures were established on the basis of spectroscopic analysis

Una observación hacia los procesos asistidos por computadora en la producción de prendas de vestir. Comparación y análisis de software CAD/CAM en Bangladesh

This research paper inquires about different attributes of Computer-aided processes in garments production. This perspective Research was done by our courageous team from 2021 to 2022. It reveals adequate information on the Garments industry's Intension and criteria for choosing CAD/CAM software. For the sake of this Research, we visited more than 600 industries to gather raw data; Every Industry tried to attend this Research from a different region of Bangladesh willingly. After collecting all raw data from the garments industry. The data of the Garments industry was coordinated by Excel program. Consequently, the data was analyzed and implemented statistically to identify the Garments Industry attribute for satisfaction with CAD/CAM software. This process also detects many challenges and defines and advises a proper solution to the problems that the Garments industry is facing in the current situation. This research paper demonstrates adequate information about the Garment's criteria and demand in purchasing garments Computer-aided software.Este trabajo de investigación indaga sobre los diferentes atributos de los procesos asistidos por computadora en la producción de prendas de vestir. Esta investigación de perspectiva fue realizada por nuestro valiente equipo de 2021 a 2022. Revela información adecuada sobre la intención de la industria de la confección y los criterios para elegir el software CAD/CAM. Por el bien de esta investigación, visitamos más de 600 industrias para recopilar datos sin procesar; Cada industria trató de asistir a esta investigación desde una región diferente de Bangladesh de buena gana. Después de recopilar todos los datos sin procesar de la industria de la confección. Los datos de la industria de Vestuario fueron coordinados por el programa Excel. En consecuencia, los datos se analizaron e implementaron estadísticamente para identificar el atributo de la industria de la confección para la satisfacción con el software CAD/CAM. Este proceso también detecta muchos desafíos y define y aconseja una solución adecuada a los problemas que enfrenta la industria de la confección en la situación actual. Este trabajo de investigación demuestra información adecuada sobre los criterios de la prenda y la demanda en la compra de prendas Software asistido por computadora

Biallelic variants in CHST3 cause Spondyloepiphyseal dysplasia with joint dislocations in three Pakistani kindreds

Background Skeletal dysplasia is a heterogeneous group of disorders. Spondyloepiphyseal dysplasias comprise one subgroup. Deficiency of carbohydrate sulfotransferase 3 has been reported in a small number of patients with recessively inherited spondyloepiphyseal dysplasia with joint dislocation, short stature and scoliosis. We report here molecular and clinical findings of affected individuals in three consanguineous Pakistani families. Affected individuals in all three families had a uniform phenotype including severe short stature, multiple dislocated joints, progressive scoliosis and facial dysmorphism. Methods Clinical evaluation was done for three unrelated families. Radiological survey of bones was completed for patients from two of the families. Whole exome sequencing index patients from each family was performed followed by Sanger sequencing for validation of segregation of identified variants in respective families. In-silico analysis for determining pathogenicity of identified variants and conservation was done. Results Whole-exome sequencing revealed biallelic variants c.590 T > C;p.(Leu197Pro), c.603C > A;p.(Tyr201Ter) and c.661C > T;p.(Arg221Cys) in CHST3 (NM_004273.5) in the three families with eight, five and two affected individuals, respectively. Contrary to previous reports, affected individuals in none of the families exhibited a hearing loss. Conclusion We describe genotypic and phenotypic findings of three unrelated families with spondyloepiphyseal dysplasia. Our study confirms phenotypic variability and adds to the genotypic spectrum of spondyloepiphyseal dysplasia.Peer reviewe

A Novel Homozygous Frameshift Variant in XYLT2 Causes Spondyloocular Syndrome in a Consanguineous Pakistani Family

We report on three new patients with spondyloocular syndrome (SOS) in a consanguineous Pakistani family. All three patients present progressive generalized osteoporosis, short stature, recurrent fractures, hearing loss and visual impairments. WES revealed a novel homozygous frameshift variant in exon 11 of XYLT2 (NG 012175.1, NP_071450.2) resulting in loss of evolutionary conserved amino acid sequences (840 – 865/865) at C-terminus p.R840fs∗115. Sanger Sequencing confirmed the presence of the novel homozygous mutation in all three patients while the parents were heterozygous carriers of the mutation, in accordance with an autosomal recessive inheritance pattern. Only nine variants worldwide have previously been reported in XYLT2 in patients with SOS phenotype. These three patients with novel homozygous variant extend the genotypic and phenotypic spectrum of SOS

Role of behavioural communication change in integrated vector management against vector borne diseases especially dengue in Punjab, Pakistan

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