585 research outputs found

    Desafíos del Estado hoy frente al no registro del trabajo doméstico entre mujeres

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    En esta ponencia se a presentan los resultados preliminares del trabajo de investigación en curso sobre las causas y fundamentos socio-culturales de la problemática del trabajo domestico femenino no registrado en la Provincia de Buenos Aires. Desde una perspectiva teórico metodológico que privilegia el punto de vista de los sujetos (trabajadoras domésticas y empleadores), el presente trabajo propone discutir y evaluar el desarrollo de políticas públicas orientadas a la regularización del servicio doméstico sosteniendo que la aplicación de tales acciones debe tener en cuenta la realdad socio- cultural y las prácticas cotidianas de los sujetos involucrados. A su vez, la investigación propone otros elementos simbólicos y culturales que deben ser analizados a hora de comprender las dificultades que enfrenta el Estado para fortalecer el registro laboral de esta actividad y la informalidad y falta de derechos sociales que la caracteriza. De ese modo, el trabajo en curso enfatiza la necesidad de interpretar el punto de vista de las trabajadoras y de analizar como estas logran, en contextos desfavorables, desarrollar e incorporar como parte de su trabajo estrategias de vida donde los actores sociales del empleo doméstico, carente de derechos y estabilidad, resulta funcional a la dinámica familiar propia, a la estructuración de la economía domestica y a la reproducción de relaciones sociale

    Determination of 5-aminosalicylic acid in pharmaceutical formulations by square wave voltammetry at pencil graphite electrodes

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    An analytical method for the determination of the anti-inflammatory drug 5-aminosalicylic acid (5-ASA) in pharmaceutical formulations using square wave voltammetry at pencil graphite electrodes was developed. After the optimization of the experimental conditions, calibration curves were obtained in the linear concentration range from 9.78 × 10-7 to 7.25 × 10-5 mol L-1 resulting in a limit of detection of 2.12 ± 0.05 x 10-8 mol L-1. Statistical tests showed that the concentrations of 5-ASA in commercial tablets and enemas obtained with the proposed voltammetric method agreed with HPLC values at a 95% confidence level.CNPqFAPES

    Nandrolone Decanoate associated with exercise training inhibit vascular endothelial growth factor (VEGF) mRNA expression in rat soleus muscle

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    Androgenic-anabolic steroids (AAS) have been used for both performance improvement and aesthetic reasons. It is well know that high doses of AAS induce serious adverse effects such as skeletal muscle injuries, including increase in the rate of muscle strains/ruptures. Vascular endothelial growth factor (VEGF) is a key factor in angiogenesis induction on both physiological and pathological conditions The aim of this study was to investigate VEGF mRNA expression in rat soleus muscle after jumping training associated with AAS administration. Wistar rats were grouped into: sedentary (S); trained without AAS (T); sedentary nandrolone decanoate (ND)-treated (AAS); and trained with AAS (AAST). The trained groups carried out jumps in water at 32°C.: 4 series of 10 jumps each, with a 30-second interval among series, for 7 weeks, with 50-80% overload of the animal corporal mass. The AAS (Decadurabolin® - 5mg/kg) was injected subcutaneously in the animal’s back twice a week. Real-time PCR analyses showed that training significantly increased VEGF mRNA expression in comparison with the S and AAS groups. When exercise training was associated with nandrolone decanoate, the VEGF mRNA expression was inhibited compared with T group. The inhibition of VEGF expression by AAS administration can decrease angiogenesis in skeletal muscle. These results suggest that the AAS may be strongly prejudicial to muscle remodeling and performance

    A study of lectin activity in buds of Sophora japonica L

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    Purpose: To identify lectins in Sophora japonica L. (green flower buds, fully formed flower buds, and flower buds as they begin to open) and to study their activity.Methods: Lectin activity was studied using rat hemagglutination method. The protein concentration of the extracts of the agglutinate was determined using Bradford assay.Results: Lectin activity of green flower buds was 1.61 ± 0.11 units/mg protein; fully formed flower buds, 1.81 ± 0.08 units/mg protein; flower buds as they began to open, and 2.05 ± 0.05 units/mg protein. The protein content of extracts from the buds of Sophora japonica L. collected at the stage of green flower buds, at the stage of formed buds, and at the stage of opening flower buds were 3.97 ± 0,04, 3.53 ± 0.07 and 3.13 ± 0.09 mg/ml respectively.Conclusion: This study shows the existence of lectins in Sophora japonica L. buds studied at three different stages of development. The highest lectin activity and protein content are found in the stage of green flower buds.Keywords: Lectins, Sophora japonica L, Flower buds, Ratuserytroagglutinatio

    Deformation and Damage Accumulation in a Ceramic Composite under Dynamic Loading

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    Methods of computer modelling were used to investigate the processes of deformation and microdamage formation in ceramic composite materials under intense dynamic loading. It was shown that there was no damage caused by dynamic compression in the vicinity of phase borders of a nanostructured aluminum oxide matrix and reinforcing particles of tetragonal zirconium dioxide. Also, the local origination of microdamages occurs only in the zones close to micropores

    Leishmania-specific surface antigens show sub-genus sequence variation and immune recognition.

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    A family of hydrophilic acylated surface (HASP) proteins, containing extensive and variant amino acid repeats, is expressed at the plasma membrane in infective extracellular (metacyclic) and intracellular (amastigote) stages of Old World Leishmania species. While HASPs are antigenic in the host and can induce protective immune responses, the biological functions of these Leishmania-specific proteins remain unresolved. Previous genome analysis has suggested that parasites of the sub-genus Leishmania (Viannia) have lost HASP genes from their genomes
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