398 research outputs found

    Daily entropy of dissolved oxygen reveals different energetic regimes and drivers among high‐mountain stream types

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    High‐resolution time series of dissolved oxygen (DO) have revealed different ecosystem energetics regimes across various stream types. Ecosystem energetic regimes are relevant to better understand the transformation and retention of nutrients and carbon in stream ecosystems. However, the patterns and controls of stream energetics in high‐mountain landscapes remain largely unknown. Here we monitored percent DO saturation (every 10 min) over 2 years in a glacier‐fed, krenal (groundwater‐fed) and a nival (snowmelt‐fed) stream as they are typical for the high mountains. We used daily Shannon entropy to explore the temporal dynamics of stream water DO and to infer information on the ecosystem energetics and on the potential drivers. We found that discharge modulated the drivers of DO variations at daily and seasonal scales. Elevated bed movement along with high turbidity and very high gas exchange rates drove the daily DO patterns in the glacier‐fed stream during snow and ice melt, whereas light seemed to drive DO dynamics in the krenal and nival streams. We found a window of favorable conditions for potential gross primary production (GPP) during the onset of the snowmelt in the glacier‐fed stream, whereas potential GPP seemed to extend over longer periods in the krenal and nival streams. Our findings suggest how the energetic regimes of these high‐mountain streams may change in the future as their biological and physical drivers change owing to climate warming

    Shuntchirurgie bei HĂ€modialysepatienten: Teil 2: Revisionen

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    Zusammenfassung: Aufgrund der demografischen Entwicklung und der ansteigenden PrĂ€valenz des Diabetes mellitus steigt die Zahl dialysepflichtiger Patienten stetig an. Bei vielen dieser Erkrankten stellt die Anlage einer autologen arterio-venösen Fistel eine echte Herausforderung dar. Im ersten Teil wurde die Thematik der Neuanlage von HĂ€modialysezugĂ€ngen besprochen. FrĂŒh- und SpĂ€tkomplikationen von Shunts wie Stenosen, VerschlĂŒsse, Aneurysmen, Infekte und Steal-Syndrom sind bei dieser chirurgischen Technik hĂ€ufig und mĂŒssen nach heute gĂŒltigen Richtlinien behandelt werden, was in diesem 2. Teil abgehandelt wir

    Shuntchirurgie bei HĂ€modialysepatienten: Teil 1: Die Erstanlage

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    Zusammenfassung: Aufgrund der demografischen Entwicklung und der ansteigenden PrĂ€valenz des Diabetes mellitus nimmt die Zahl dialysepflichtiger Patienten stetig zu. Bei vielen dieser Erkrankten stellt die Anlage einer autologen arterio-venösen Fistel eine echte Herausforderung dar. Erweist sie sich als unmöglich, muss der GefĂ€ĂŸchirurg mit alternativen ZugĂ€ngen sowie den Vor- und Nachteilen von alloplastischen und heterologen Prothesen vertraut sein (Teil 1). FrĂŒh- und SpĂ€tkomplikationen wie Aneurysmen, Stenosen, VerschlĂŒsse, Infekte und Steal-Syndrom sind in der Shuntchirurgie hĂ€ufig und sollten nach heute gĂŒltigen Richtlinien behandelt werden (Teil 2

    Does continuous renal replacement therapy favourably influence the outcome of the patients?

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    Continuous haemodialysis and continuous haemofiltration are efficient and safe techniques for the treatment of acute renal failure. Theoretical advantages are improved haemodynamic stability and easier fluid removal. All 15 available studies comparing intermittent (522 patients) with continuous (651 patients) renal replacement therapy have been reviewed. From these studies it cannot be established, whether the use of a continuous instead of an intermittent treatment modality improves the outcome in patients with acute renal failure. Reviewing all 67 published studies dealing with continuous renal replacement therapy revealed a trend to a decreasing mortality rate (P<0.08) over the last 11 years, whereas the mean age and the severity of illness of the patients, measured by the APACHE II score, did not change. In order to establish whether the quality of treatment has improved as a function of time, two quality factors (QF) were created, i.e. QF for age (mean age/mean mortality rate of the patients treated) and QF for severity of diseases (mean APACHE II/mean mortality rate). Both QF improved from 1984 until 1994, when analyzed for continuous (P<0.001) or intermittent (P<0.001) treatment modality. Thus the quality of treatment of patients with acute renal failure improved during the last decade. However, there is no evidence with respect to survival rate that a continuous renal replacement therapy is superior to an intermittent on

    Quantitative Determination of Temperature in the Approach to Magnetic Order of Ultracold Fermions in an Optical Lattice

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    We perform a quantitative simulation of the repulsive Fermi-Hubbard model using an ultracold gas trapped in an optical lattice. The entropy of the system is determined by comparing accurate measurements of the equilibrium double occupancy with theoretical calculations over a wide range of parameters. We demonstrate the applicability of both high-temperature series and dynamical mean-field theory to obtain quantitative agreement with the experimental data. The reliability of the entropy determination is confirmed by a comprehensive analysis of all systematic errors. In the center of the Mott insulating cloud we obtain an entropy per atom as low as 0.77k(B) which is about twice as large as the entropy at the Neel transition. The corresponding temperature depends on the atom number and for small fillings reaches values on the order of the tunneling energy

    Haemodialysis activates phospholipase A2 enzyme

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    Background Clinical and experimental evidence suggest that haemodialysis (HD) procedure is an inflammatory process. For the production of proinflammatory lipid mediators in many inflammatory reactions, the release of arachidonic acid by phospholipase A2 (PLA2 enzyme is a prerequisite. Therefore, the purpose of the present investigation was to establish whether the activity of PLA2 increases during HD and whether the increase depends on the type of dialyser used. Methods We performed dialysis in eight chronic HD patients. Blood samples entering and leaving the dialyser were obtained before and at 15, 60, 120 and 180 min after the dialysis was started, on one occasion using a cuprophane and on another occasion a cellulose triacetate dialyser. PLA2 activity was assessed in crude plasma and in plasma extract. Results PLA2 activity in plasma extract exhibited similar biochemical properties to that of inflammatory human synovial fluid PLA2 enzyme which is of group II PLA2. PLA2 activity in crude plasma represents a type of PLA2 other than the synovial type. In HD patients, baseline PLA2 activities in crude plasma and plasma extract were significantly increased when compared to normal subjects. An increase in PLA2 activity was observed in crude plasma with a peak appearing at 15 min when the patients were dialysed with cuprophane and cellulose triacetate membranes. This increase was observed in both arterial and venous blood samples and was more pronounced when the patients were dialysed with cuprophane than with cellulose triacetate membranes. When PLA2 was assessed in plasma extract, the activity increased only with cuprophane but not with cellulose triacetate membranes. Conclusions PLA2 activity in plasma is increased in HD patients and increases during the dialysis procedure to a greater extent with a less biocompatible membrane. Continuous activation of PLA2 might be relevant for long-term deleterious consequences of H

    Hemodynamic Modeling of the Intrarenal Circulation

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    Three dimensional, time dependent numerical simulations of healthy and pathological conditions in a model kidney were performed. Blood flow in a kidney is not commonly investigated by computational approach, in contrast for example, to the flow in a heart. The flow in a kidney is characterized by relatively small Reynolds number (100<Re<0.01—laminar regime). The presented results give insight into the structure of such flow, which is hard to measure in vivo. The simulations have suggested that venous thrombosis is more likely than arterial thrombosis—higher shear rate observed. The obtained maximum velocity, as a result of the simulations, agrees with the observed in vivo measurements. The time dependent simulations show separation regimes present in the vicinity of the maximum pressure value. The pathological constriction introduced to the arterial geometry leads to the changes in separation structures. The constriction of a single vessel affects flow in the whole kidney. Pathology results in different flow rate values in healthy and affected branches, as well as, different pulsate cycle characteristic for the whole syste

    Artificial graphene as a tunable Dirac material

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    Artificial honeycomb lattices offer a tunable platform to study massless Dirac quasiparticles and their topological and correlated phases. Here we review recent progress in the design and fabrication of such synthetic structures focusing on nanopatterning of two-dimensional electron gases in semiconductors, molecule-by-molecule assembly by scanning probe methods, and optical trapping of ultracold atoms in crystals of light. We also discuss photonic crystals with Dirac cone dispersion and topologically protected edge states. We emphasize how the interplay between single-particle band structure engineering and cooperative effects leads to spectacular manifestations in tunneling and optical spectroscopies.Comment: Review article, 14 pages, 5 figures, 112 Reference
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