Atomic transition frequencies, isotope shifts, and sensitivity to variation of the fine structure constant for studies of quasar absorption spectra

Theories unifying gravity with other interactions suggest spatial and temporal variation of fundamental "constants" in the Universe. A change in the fine structure constant, alpha, could be detected via shifts in the frequencies of atomic transitions in quasar absorption systems. Recent studies using 140 absorption systems from the Keck telescope and 153 from the Very Large Telescope, suggest that alpha varies spatially. That is, in one direction on the sky alpha seems to have been smaller at the time of absorption, while in the opposite direction it seems to have been larger. To continue this study we need accurate laboratory measurements of atomic transition frequencies. The aim of this paper is to provide a compilation of transitions of importance to the search for alpha variation. They are E1 transitions to the ground state in several different atoms and ions, with wavelengths ranging from around 900 - 6000 A, and require an accuracy of better than 10^{-4} A. We discuss isotope shift measurements that are needed in order to resolve systematic effects in the study. The coefficients of sensitivity to alpha-variation (q) are also presented.Comment: Includes updated version of the "alpha line" lis

Parafermionic Liouville field theory and instantons on ALE spaces

In this paper we study the correspondence between the $\hat{\textrm{su}}(n)_{k}\oplus \hat{\textrm{su}}(n)_{p}/\hat{\textrm{su}}(n)_{k+p}$ coset conformal field theories and $\mathcal{N}=2$ SU(n) gauge theories on $\mathbb{R}^{4}/\mathbb{Z}_{p}$. Namely we check the correspondence between the SU(2) Nekrasov partition function on $\mathbb{R}^{4}/\mathbb{Z}_{4}$ and the conformal blocks of the $S_{3}$ parafermion algebra (in $S$ and $D$ modules). We find that they are equal up to the U(1)-factor as it was in all cases of AGT-like relations. Studying the structure of the instanton partition function on $\mathbb{R}^4/\mathbb{Z}_p$ we also find some evidence that this correspondence with arbitrary $p$ takes place up to the U(1)-factor.Comment: 21 pages, 6 figures, misprints corrected, references added, version to appear in JHE

Theoretical Uncertainties in Electroweak Boson Production Cross Sections at 7, 10, and 14 TeV at the LHC

We present an updated study of the systematic errors in the measurements of the electroweak boson cross-sections at the LHC for various experimental cuts for a center of mass energy of 7, 10 and 14 TeV. The size of both electroweak and NNLO QCD contributions are estimated, together with the systematic error from the parton distributions. The effects of new versions of the MSTW, CTEQ, and NNPDF PDFs are considered.Comment: PDFLatex with JHEP3.cls. 22 pages, 43 figures. Version 2 adds the CT10W PDF set to analysis and updates the final systematic error table and conclusions, plus several citations and minor wording changes. Version 3 adds some references on electroweak and mixed QED/QCD corrections. Version 4 adds more references and acknowledgement

Manipulation of drugs to achieve the required dose is intrinsic to paediatric practice but is not supported by guidelines or evidence

Background: A lack of age-appropriate formulations can make it difficult to administer medicines to children. A manipulation of the dosage form may be required to achieve the required dose. This study aimed to describe medicines that are manipulated to achieve the required dose in paediatric practice.Method: A structured, undisguised observational study and postal survey. The observational study investigated drug manipulations occurring in clinical practice across three sites. The questionnaire, administered to a sample of paediatric nurses throughout the UK, surveyed manipulations conducted and nurses' experiences and views.Results: The observational study identified 310 manipulations, of which 62% involved tablets, 21% were intravenous drugs and 10% were sachets. Of the 54 observed manipulations 40 involved tablets with 65% of the tablets being cut and 30% dispersed to obtain a smaller dose. 188 manipulations were reported by questionnaire respondents, of these 46% involved tablets, 12% were intravenous drugs, and 12% were nebuliser solutions. Manipulations were predominantly, but not exclusively, identified in specialist clinical areas with more highly dependent patients. Questionnaire respondents were concerned about the accuracy of the dose achieved following manipulations and the lack of practice guidance.Conclusion: Manipulations to achieve the required dose occur throughout paediatric in-patient settings. The impact of manipulations on the efficacy of the drugs, the accuracy of the dose and any adverse effects on patients is not known. There is a need to develop evidence-based guidance for manipulations of medicines in children

Combination of electroweak and QCD corrections to single W production at the Fermilab Tevatron and the CERN LHC

Precision studies of the production of a high-transverse momentum lepton in association with missing energy at hadron colliders require that electroweak and QCD higher-order contributions are simultaneously taken into account in theoretical predictions and data analysis. Here we present a detailed phenomenological study of the impact of electroweak and strong contributions, as well as of their combination, to all the observables relevant for the various facets of the p\smartpap \to {\rm lepton} + X physics programme at hadron colliders, including luminosity monitoring and Parton Distribution Functions constraint, $W$ precision physics and search for new physics signals. We provide a theoretical recipe to carefully combine electroweak and strong corrections, that are mandatory in view of the challenging experimental accuracy already reached at the Fermilab Tevatron and aimed at the CERN LHC, and discuss the uncertainty inherent the combination. We conclude that the theoretical accuracy of our calculation can be conservatively estimated to be about 2% for standard event selections at the Tevatron and the LHC, and about 5% in the very high $W$ transverse mass/lepton transverse momentum tails. We also provide arguments for a more aggressive error estimate (about 1% and 3%, respectively) and conclude that in order to attain a one per cent accuracy: 1) exact mixed ${\cal O}(\alpha \alpha_s)$ corrections should be computed in addition to the already available NNLO QCD contributions and two-loop electroweak Sudakov logarithms; 2) QCD and electroweak corrections should be coherently included into a single event generator.Comment: One reference added. Final version to appear in JHE

Hopf algebras, coproducts and symbols: an application to Higgs boson amplitudes

We show how the Hopf algebra structure of multiple polylogarithms can be used to simplify complicated expressions for multi-loop amplitudes in perturbative quantum field theory and we argue that, unlike the recently popularized symbol-based approach, the coproduct incorporates information about the zeta values. We illustrate our approach by rewriting the two-loop helicity amplitudes for a Higgs boson plus three gluons in a simplified and compact form involving only classical polylogarithms.Comment: 46 page

Lorentzian and Euclidean Quantum Gravity - Analytical and Numerical Results

We review some recent attempts to extract information about the nature of quantum gravity, with and without matter, by quantum field theoretical methods. More specifically, we work within a covariant lattice approach where the individual space-time geometries are constructed from fundamental simplicial building blocks, and the path integral over geometries is approximated by summing over a class of piece-wise linear geometries. This method of ``dynamical triangulations'' is very powerful in 2d, where the regularized theory can be solved explicitly, and gives us more insights into the quantum nature of 2d space-time than continuum methods are presently able to provide. It also allows us to establish an explicit relation between the Lorentzian- and Euclidean-signature quantum theories. Analogous regularized gravitational models can be set up in higher dimensions. Some analytic tools exist to study their state sums, but, unlike in 2d, no complete analytic solutions have yet been constructed. However, a great advantage of our approach is the fact that it is well-suited for numerical simulations. In the second part of this review we describe the relevant Monte Carlo techniques, as well as some of the physical results that have been obtained from the simulations of Euclidean gravity. We also explain why the Lorentzian version of dynamical triangulations is a promising candidate for a non-perturbative theory of quantum gravity.Comment: 69 pages, 16 figures, references adde

Ocean warming enhances respiration and carbon demand of coastal microbial plankton

Abstract The increase of anthropogenic CO 2 during this century is expected to cause warming of large regions of the ocean. Microbes lead the biological role in the CO 2 balance of marine ecosystems, their activity is known to be influenced by temperature, and it is important to constrain and quantify these effects on bacterial carbon use. Furthermore, if warming were to enhance the carbon demand (production 1 respiration) of planktonic microbes but would maintain their efficiency low (as it generally is), then most carbon consumed would end up respired. We designed a strategy in which we measured bacterial production and respiration throughout a seasonal cycle in a coastal Mediterranean site, and determined experimentally the effects of ca. 2.5 1C on these processes. We show that warming will increase nearly 20% the total carbon demand of coastal microbial plankton without any effect on their (commonly low) growth efficiency, which could generate a positive feedback between coastal warming and CO 2 production

Instanton partition functions in N=2 SU(N) gauge theories with a general surface operator, and their W-algebra duals

We write down an explicit conjecture for the instanton partition functions in 4d N=2 SU(N) gauge theories in the presence of a certain type of surface operator. These surface operators are classified by partitions of N, and for each partition there is an associated partition function. For the partition N=N we recover the Nekrasov formalism, and when N=1+...+1 we reproduce the result of Feigin et. al. For the case N=1+(N-1) our expression is consistent with an alternative formulation in terms of a restricted SU(N)xSU(N) instanton partition function. When N=1+...+1+2 the partition functions can also be obtained perturbatively from certain W-algebras known as quasi-superconformal algebras, in agreement with a recent general proposal.Comment: 20 page

Theoretical study of the insulating oxides and nitrides: SiO2, GeO2, Al2O3, Si3N4, and Ge3N4

An extensive theoretical study is performed for wide bandgap crystalline oxides and nitrides, namely, SiO_{2}, GeO_{2}, Al_{2}O_{3}, Si_{3}N_{4}, and Ge_{3}N_{4}. Their important polymorphs are considered which are for SiO_{2}: $\alpha$-quartz, $\alpha$- and $\beta$-cristobalite and stishovite, for GeO_{2}: $\alpha$-quartz, and rutile, for Al_{2}O_{3}: $\alpha$-phase, for Si_{3}N_{4} and Ge_{3}N_{4}: $\alpha$- and $\beta$-phases. This work constitutes a comprehensive account of both electronic structure and the elastic properties of these important insulating oxides and nitrides obtained with high accuracy based on density functional theory within the local density approximation. Two different norm-conserving \textit{ab initio} pseudopotentials have been tested which agree in all respects with the only exception arising for the elastic properties of rutile GeO_{2}. The agreement with experimental values, when available, are seen to be highly satisfactory. The uniformity and the well convergence of this approach enables an unbiased assessment of important physical parameters within each material and among different insulating oxide and nitrides. The computed static electric susceptibilities are observed to display a strong correlation with their mass densities. There is a marked discrepancy between the considered oxides and nitrides with the latter having sudden increase of density of states away from the respective band edges. This is expected to give rise to excessive carrier scattering which can practically preclude bulk impact ionization process in Si_{3}N_{4} and Ge_{3}N_{4}.Comment: Published version, 10 pages, 8 figure