Critical current diffraction pattern of SIFS Josephson junctions with step-like F-layer

We present the latest generation of superconductor-insulator-ferromagnet-superconductor Josephson tunnel junctions with a step-like thickness of the ferromagnetic (F) layer. The F-layer thicknesses $d_1$ and $d_2$ in both halves were varied to obtain different combinations of positive and negative critical current densities $j_{c,1}$ and $j_{c,2}$. The measured dependences of the critical current on applied magnetic field can be well described by a model which takes into account different critical current densities (obtained from reference junctions) and different net magnetization of the multidomain ferromagnetic layer in both halves.Comment: 7 pages, 3 figure

Spectroscopy of a fractional Josephson vortex molecule

In long Josephson junctions with multiple discontinuities of the Josephson phase, fractional vortex molecules are spontaneously formed. At each discontinuity point a fractional Josephson vortex carrying a magnetic flux $|\Phi|<\Phi_0$, $\Phi_0\approx 2.07\times 10^{-15}$ Wb being the magnetic flux quantum, is pinned. Each vortex has an oscillatory eigenmode with a frequency that depends on $\Phi/\Phi_0$ and lies inside the plasma gap. We experimentally investigate the dependence of the eigenfrequencies of a two-vortex molecule on the distance between the vortices, on their topological charge $\wp=2\pi\Phi/\Phi_0$ and on the bias current $\gamma$ applied to the Josephson junction. We find that with decreasing distance between vortices, a splitting of the eigenfrequencies occurs, that corresponds to the emergence of collective oscillatory modes of both vortices. We use a resonant microwave spectroscopy technique and find good agreement between experimental results and theoretical predictions.Comment: submitted to Phys. Rev.

A tunable macroscopic quantum system based on two fractional vortices

We propose a tunable macroscopic quantum system based on two fractional vortices. Our analysis shows that two coupled fractional vortices pinned at two artificially created \kappa\ discontinuities of the Josephson phase in a long Josephson junction can reach the quantum regime where coherent quantum oscillations arise. For this purpose we map the dynamics of this system to that of a single particle in a double-well potential. By tuning the \kappa\ discontinuities with injector currents we are able to control the parameters of the effective double-well potential as well as to prepare a desired state of the fractional vortex molecule. The values of the parameters derived from this model suggest that an experimental realisation of this tunable macroscopic quantum system is possible with today's technology.Comment: We updated our manuscript due to a change of the focus from qubit to macroscopic quantum effect

Quantum tunneling of semifluxons

We consider a system of two semifluxons of opposite polarity in a 0-pi-0 long Josephson junction, which classically can be in one of two degenerate states: up-down or down-up. When the distance $a$ between the 0-pi boundaries (semifluxon's centers) is a bit larger than the crossover distance $a_c$, the system can switch from one state to the other due to thermal fluctuations or quantum tunneling. We map this problem to the dynamics of a single particle in a double well potential and estimate parameters for which quantum effects emerge. We also determine the classical-to-quantum crossover temperature as well as the tunneling rate (energy level splitting) between the states up-down and down-up.Comment: submitted to PRB, comments/questions are welcom

Thermal escape of fractional vortices in long Josephson junctions

We consider a fractional Josephson vortex in a long 0-kappa Josephson junction. A uniformly applied bias current exerts a Lorentz force on the vortex. If the bias current exceeds the critical current, an integer fluxon is torn off the kappa-vortex and the junction switches to the voltage state. In the presence of thermal fluctuations the escape process takes place with finite probability already at subcritical values of the bias current. We experimentally investigate the thermally induced escape of a fractional vortex by high resolution measurements of the critical current as a function of the topological charge kappa of the vortex and compare the results to numerical simulations for finite junction lengths and to theoretical predictions for infinite junction lengths. To study the effect caused by the junction geometry we compare the vortex escape in annular and linear junctions.Comment: submitted to PR

Theory of fractional vortex escape in a 0-kappa long Josephson junction

We consider a fractional Josephson vortex in an infinitely long 0-kappa Josephson junction. A uniform bias current applied to the junction exerts a Lorentz force acting on a vortex. When the bias current becomes equal to the critical (or depinning) current, the Lorentz force tears away an integer fluxon and the junction switches to the resistive state. In the presence of thermal and quantum fluctuations this escape process takes place with finite probability already at subcritical values of the bias current. We analyze the escape of a fractional vortex by mapping the Josephson phase dynamics to the dynamics of a single particle in a metastable potential and derive the effective parameters of this potential. This allows us to predict the behavior of the escape rate as a function of the topological charge of the vortex

Quantitative nanoscale vortex-imaging using a cryogenic quantum magnetometer

Microscopic studies of superconductors and their vortices play a pivotal role in our understanding of the mechanisms underlying superconductivity. Local measurements of penetration depths or magnetic stray-fields enable access to fundamental aspects of superconductors such as nanoscale variations of superfluid densities or the symmetry of their order parameter. However, experimental tools, which offer quantitative, nanoscale magnetometry and operate over the large range of temperature and magnetic fields relevant to address many outstanding questions in superconductivity, are still missing. Here, we demonstrate quantitative, nanoscale magnetic imaging of Pearl vortices in the cuprate superconductor YBCO, using a scanning quantum sensor in form of a single Nitrogen-Vacancy (NV) electronic spin in diamond. The sensor-to-sample distance of ~10nm we achieve allows us to observe striking deviations from the prevalent monopole approximation in our vortex stray-field images, while we find excellent quantitative agreement with Pearl's analytic model. Our experiments yield a non-invasive and unambiguous determination of the system's local London penetration depth, and are readily extended to higher temperatures and magnetic fields. These results demonstrate the potential of quantitative quantum sensors in benchmarking microscopic models of complex electronic systems and open the door for further exploration of strongly correlated electron physics using scanning NV magnetometry.Comment: Main text (5 pages, 4 figures) plus supplementary material (5 pages, 6 figures). Comments welcome. Further information under http://www.quantum-sensing.c

A COMPARISON OF CHOLINESTERASE DISTRIBUTION IN THE CEREBELLUM OF SEVERAL SPECIES *

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65142/1/j.1471-4159.1964.tb06717.x.pd

Air traffic and contrail changes over Europe during COVID-19: a model study

The strong reduction of air traffic during the COVID-19 pandemic provides a unique test case for the relationship between air traffic density, contrails, and their radiative forcing of climate change. Here, air traffic and contrail cirrus changes are quantified for a European domain for March to August 2020 and compared to the same period in 2019. Traffic data show a 72 % reduction in flight distance compared with 2019. This paper investigates the induced contrail changes in a model study. The contrail model results depend on various methodological details as discussed in parameter studies. In the reference case, the reduced traffic caused a reduction in contrail length. The reduction is slightly stronger than expected from the traffic change because the weather conditions in 2020 were less favorable for contrail formation than in 2019. Contrail coverage over Europe with an optical depth larger than 0.1 decreased from 4.6 % in 2019 to 1.4 % in 2020; the total cirrus cover amount changed by 28 % to 25 %. The reduced contrail coverage caused 70 % less longwave and 73 % less shortwave radiative forcing but, because of various nonlinearities, only 54 % less net forcing in this case. The methods include recently developed models for performance parameters and soot emissions. The overall propulsion efficiency of the aircraft is about 20 % smaller than estimated in earlier studies, resulting in 3 % fewer contrails. Considerable sensitivity to soot emissions is found, highlighting fuel and engine importance. The contrail model includes a new approximate method to account for water vapor exchange between contrails and background air and for radiative forcing changes due to contrail–contrail overlap. The water vapor exchange reduces available ice supersaturation in the atmosphere, which is critical for contrail formation. Contrail–contrail overlap changes the computed radiative forcing considerably. Comparisons to satellite observations are described and discussed in a parallel publication

Development of an in-vivo active reversible butyrylcholinesterase inhibitor

Alzheimer’s disease (AD) is characterized by severe basal forebrain cholinergic deficit, which results in progressive and chronic deterioration of memory and cognitive functions. Similar to acetylcholinesterase, butyrylcholinesterase (BChE) contributes to the termination of cholinergic neurotransmission. Its enzymatic activity increases with the disease progression, thus classifying BChE as a viable therapeutic target in advanced AD. Potent, selective and reversible human BChE inhibitors were developed. The solved crystal structure of human BChE in complex with the most potent inhibitor reveals its binding mode and provides the molecular basis of its low nanomolar potency. Additionally, this compound is noncytotoxic and has neuroprotective properties. Furthermore, this inhibitor moderately crosses the blood-brain barrier and improves memory, cognitive functions and learning abilities of mice in a model of the cholinergic deficit that characterizes AD, without producing acute cholinergic adverse effects. Our study provides an advanced lead compound for developing drugs for alleviating symptoms caused by cholinergic hypofunction in advanced AD