29 research outputs found

    Typology and Factorial Conditioning of Suicidal Behavior of Adolescents

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    The problem of suicidal behavior of an individual continues to remain relevant, due to the increase in the number of suicides among people of different ages, on the one hand, and insufficient information about the factors of suicidal behavior of an individual. The purpose of the study is to identify the factors that determine the formation of a certain type of personality who committed suicidal attempts in adolescence. In order to identify the types of adolescent suicides, there was conducted a survey of 20 doctors in psychiatric clinical hospitals in Moscow. The survey results were processed using cluster analysis. To identify the factorial conditioning of suicidal behavior of each personality type, a complex of psychodiagnostic techniques was used, focused on the study of the characteristics of the emotional, value-semantic and behavioral spheres of the personality. The obtained empirical data were processed with the help of factor analysis. Three clusters have been identified that combine similar personality characteristics of suicides. It was specified that among adolescents there are the following personality types: “militant” (22%), “sacrifice” (54%) and “self-deprecating” (24%). Each type of adolescent suicide is due to the characteristics of the emotional, value-semantic and behavioral spheres of their personality. To develop targeted programs for the prevention of suicidal behavior among adolescents, it is necessary to take into account the results of the study, since such programs should be aimed at blocking the factors that form a certain type of suicide

    Typology and Factorial Conditioning of Suicidal Behavior of Adolescents

    Get PDF
    The problem of suicidal behavior of an individual continues to remain relevant, due to the increase in the number of suicides among people of different ages, on the one hand, and insufficient information about the factors of suicidal behavior of an individual. The purpose of the study is to identify the factors that determine the formation of a certain type of personality who committed suicidal attempts in adolescence. In order to identify the types of adolescent suicides, there was conducted a survey of 20 doctors in psychiatric clinical hospitals in Moscow. The survey results were processed using cluster analysis. To identify the factorial conditioning of suicidal behavior of each personality type, a complex of psychodiagnostic techniques was used, focused on the study of the characteristics of the emotional, value-semantic and behavioral spheres of the personality. The obtained empirical data were processed with the help of factor analysis. Three clusters have been identified that combine similar personality characteristics of suicides. It was specified that among adolescents there are the following personality types: “militant” (22%), “sacrifice” (54%) and “self-deprecating” (24%). Each type of adolescent suicide is due to the characteristics of the emotional, value-semantic and behavioral spheres of their personality. To develop targeted programs for the prevention of suicidal behavior among adolescents, it is necessary to take into account the results of the study, since such programs should be aimed at blocking the factors that form a certain type of suicide

    Typology and Factorial Conditioning of Suicidal Behavior of Adolescents

    Get PDF
    The problem of suicidal behavior of an individual continues to remain relevant, due to the increase in the number of suicides among people of different ages, on the one hand, and insufficient information about the factors of suicidal behavior of an individual. The purpose of the study is to identify the factors that determine the formation of a certain type of personality who committed suicidal attempts in adolescence. In order to identify the types of adolescent suicides, there was conducted a survey of 20 doctors in psychiatric clinical hospitals in Moscow. The survey results were processed using cluster analysis. To identify the factorial conditioning of suicidal behavior of each personality type, a complex of psychodiagnostic techniques was used, focused on the study of the characteristics of the emotional, value-semantic and behavioral spheres of the personality. The obtained empirical data were processed with the help of factor analysis. Three clusters have been identified that combine similar personality characteristics of suicides. It was specified that among adolescents there are the following personality types: “militant” (22%), “sacrifice” (54%) and “self-deprecating” (24%). Each type of adolescent suicide is due to the characteristics of the emotional, value-semantic and behavioral spheres of their personality. To develop targeted programs for the prevention of suicidal behavior among adolescents, it is necessary to take into account the results of the study, since such programs should be aimed at blocking the factors that form a certain type of suicide

    Water-soluble hybrid materials based on {Mo₆X₈}⁎âș (X = Cl, Br, I) cluster complexes and sodium polystyrene sulfonate

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    Development of water-soluble forms of octahedral molybdenum clusters {Mo₆X₈}⁎âș (X = Cl, Br, I) is strongly motivated by the tremendous potential that these complexes have for biological applications, namely as agents for bioimaging and photodynamic therapy. In these work we report the first water-soluble hybrid materials, which represent sodium polystyrene sulfonate doped by molybdenum clusters, and evaluation of their photophysical and biological properties (dark and photoinduced cytotoxicity and cellular uptake) with the use of cervical cancer (HeLa) and human epidermoid larynx carcinoma (Hep-2) cell-lines as models

    The complete mitochondrial genome of the extinct Pleistocene horse (Equus cf. lenensis) from Kotelny Island (New Siberian Islands, Russia) and its phylogenetic assessment

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    The complete mitochondrial genome from the Pleistocene stallion horse (Equus cf. lenensis) which complete skull was found in 1901 on Kotelny Island (New Siberian Archipelago, Sakha Republic, Russia) is published in this paper. The mitochondrial DNA (mtDNA) is 16,584 base pairs (bp) in length and contained 13 protein-coding genes, 2 rRNA genes, 22 tRNA genes. The overall base composition of the genome in descending order was 32.3% – A, 28.5% – C, 13.4% – G, 25.8% - T without a significant AT bias of 58.2%.publishedVersio

    Molecular phylogeny of one extinct and two critically endangered Central Asian sturgeon species (genus Pseudoscaphirhynchus) based on their mitochondrial genomes

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    The enigmatic and poorly studied sturgeon genus Pseudoscaphirhynchus (Scaphirhynchinae: Acipenseridae) comprises three species: the Amu Darya shovelnose sturgeon (Pseudoscaphirhynchus kaufmanni (Bogdanow)), dwarf Amu Darya shovelnose sturgeon P. hermanni (Kessler), and Syr Darya shovelnose sturgeon (P. fedtschenkoi (Bogdanow). Two species – P. hermanni and P. kaufmanni – are critically endangered due to the Aral Sea area ecological disaster, caused by massive water use for irrigation to support cotton agriculture, subsequent pesticide pollution and habitat degradation. For another species – P. fedtschenkoi – no sightings have been reported since 1960-s and it is believed to be extinct, both in nature and in captivity. In this study, complete mitochondrial (mt) genomes of these three species of Pseudoscaphirhynchus were characterized using Illumina and Sanger sequencing platforms. Phylogenetic analyses showed the significant divergence between Amu Darya and Syr Darya freshwater sturgeons and supported the monophyletic origin of the Pseudoscaphirhynchus species. We confirmed that two sympatric Amu Darya species P. kaufmanni and P. hermanni form a single genetic cluster, which may require further morphological and genetic study to assess possible hybridization, intraspecific variation and taxonomic status and to develop conservation measures to protect these unique fishes.publishedVersio

    Biantennary oligoglycines and glyco-oligoglycines self-associating in aqueous medium

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    Oligoglycines designed in a star-like fashion, so-called tri- and tetraantennary molecules, were found to form highly ordered supramers in aqueous medium. The formation of these supramers occurred either spontaneously or due to the assistance of a mica surface. The driving force of the supramer formation is hydrogen bonding, the polypeptide chain conformation is related to the folding of helical polyglycine II (PG II). Tri- and tetraantennary molecules are capable of association if the antenna length reach 7 glycine (Gly) residues. Properties of similar biantennary molecules have not been investigated yet, and we compared their self-aggregating potency with similar tri- and tetraantennary analogs. Here, we synthesized oligoglycines of the general formula R-Glyn-Đ„-Glyn-R (X = -HN-(СН2)m-NH-, m = 2, 4, 10; n = 1–7) without pendant ligands (R = H) and with two pendant sialoligands (R = sialic acid or sialooligosaccharide). Biantennary oligoglycines formed PG II aggregates, their properties, however, differ from those of the corresponding tri- and tetraantennary oligoglycines. In particular, the tendency to aggregate starts from Gly4 motifs instead of Gly7. The antiviral activity of end-glycosylated peptides was studied, and all capable of assembling glycopeptides demonstrated an antiviral potency which was up to 50 times higher than the activity of peptide-free glycans
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