Propuesta de intervención psicopedagógica en resiliencia con hijas e hijos de víctimas de violencia de género

Ante la preocupación actual y personal sobre la violencia de género como principal obstáculo en el camino hacia la plena igualdad entre hombres y mujeres, este trabajo se centrará en la intervención con las personas que sufren este tipo de violencia. Una de las debilidades encontradas en esta meta global, es la atención que se presta a las niñas y niños que viven esta violencia en sus hogares. Por ello, este trabajo se apoya en documentación relevante sobre la violencia de género, con el fin de comprender las consecuencias de la convivencia de los menores en un contexto familiar de violencia de género, tratarlos como un colectivo en el que existen una serie de necesidades a analizar y encontrar recursos y herramientas que les ayuden a su recuperación y su continuidad vital de una forma sana y positiva. En el camino, se verá como la promoción de la Resiliencia es una de las formas más completas para poder intervenir en sus necesidades y abrir diversas vías para continuar con su vida, sin que el trauma condicione su desarrollo. Con esta fundamentación como base, se propone una intervención a través de un programa, que por su variabilidad, puede llegar a un gran grupo de niñas y niños y por su generalidad permite amoldarse a las necesidades individuales de cada grupo y de cada niña y niño.Because of the current concern about gender-based violence as the main obstacle on the way to full equality between men and women. This work focuses of the intervention with all those suffering this type of violence. One of the weak points found in this global goal is the attention paid to those girls and boys who experience this type of violence in their homes. Therefore, this End-of-Master’s Project collects relevant documentation on gender-based violence in order to reach its the consequences in those children, to treat them as a group in which there are a series of specific needs and finally to analyze and find resources and tools that help minors to their recovery and to ensure the continuity of their lives in a healthy and positive way Along the way, it will see how the promotion of Resilience is one of the most complete ways to intervene directly in those children’s needs and helps to create other open diverse paths to support themselves in order to continue with their life without trauma conditions their development. With this basis and foundation, this project proposes an intervention through an action plan that, due to its variability, can reach a large group of children and, due to its general nature, allows to be adapted to the individual needs of each group and of each child.Departamento de PsicologíaMáster en Psicopedagogí

Modeling Horizontal Ultraviolet Irradiance for All Sky Conditions by Using Artificial Neural Networks and Regression Models

In the present study, different models constructed with meteorological variables are proposed for the determination of horizontal ultraviolet irradiance (IUV), on the basis of data collected at Burgos (Spain) during an experimental campaign between March 2020 and May 2022. The aim is to explore the effectiveness of a range of variables for modelling horizontal ultraviolet irradiance through a comparison of supervised artificial neural network (ANN) and regression model results. A preliminary feature selection process using the Pearson correlation coefficient was sufficient to determine the variables for use in the models. The following variables and their influence on horizontal ultraviolet irradiance were analyzed: horizontal global irradiance (IGH), clearness index (kt), solar altitude angle (α), horizontal beam irradiance (IBH), diffuse fraction (D), temperature (T), sky clearness (ε), cloud cover (Cc), horizontal diffuse irradiance (IDH), and sky brightness (∆). The ANN models yielded results of greater accuracy than the regression models.This research is a result of the project RTI2018-098900-B-I00 financed by the Spanish Ministry of Science and Innovation, project TED2021-131563B-I00 financed by MCIN/AEI/10.13039/501100011033 and the European Union “NextGenerationEU”/PRTR», and Junta de Castilla y León, under grant number INVESTUN/19/BU/0004

Serum nuclear magnetic resonance metabolomics analysis of human metastatic colorectal cancer: Biomarkers and pathway analysis

Junta de Andalucía, Grant/Award Numbers: 102C2000004, UAL2020-AGR-B1781, P20_01041; Gobierno de España, Grant/Award Numbers: PDC2021– 121248-I00, PLEC2021–007774; Instituto de Salud Carlos III (ISCIII), Grant/Award Number: PI19/01478; CTS-107 and FQM-376 groupsWe describe the use of nuclear magnetic resonance metabolomics to analyze blood serum samples from healthy individuals (n = 26) and those with metastatic colorectal cancer (CRC; n = 57). The assessment, employing both linear and nonlinear multivari- ate data analysis techniques, revealed specific metabolite changes associated with metastatic CRC, including increased levels of lactate, glutamate, and pyruvate, and decreased levels of certain amino acids and total fatty acids. Biomarker ratios such as glutamate-to-glutamine and pyruvate-to-alanine were also found to be related to CRC. The study also found that glutamate was linked to progression-free survival and that both glutamate and 3-hydroxybutyrate were risk factors for metastatic CRC. Additionally, gas chromatography coupled to flame-ionization detection was utilized to analyze the fatty acid profile and pathway analysis was performed on the profiled metabolites to understand the metabolic processes involved in CRC. A correlation was also found between the presence of certain metabolites in the blood of CRC patients and certain clinical features.Junta de Andalucia 102C2000004, UAL2020-AGR-B1781, P20_01041Gobierno de España MCIN/AEI/10.13039/501100011033/Unión Europea “Next GenerationEU”/PRTR (PDC2021–121248-I00 and PLEC2021–007774)Instituto de Salud Carlos III (ISCIII) (PI19/01478) (FEDER)CTS-107FQM-37

Retrieval of monthly average hourly values of direct and diffuse solar irradiance from measurements of global radiation in Spain

An exhaustive evaluation of the performance of decomposition models to estimate direct and diffuse components from the global horizontal solar irradiance has been carried out in this work. The main objective of this work has been to compare the model performance for two different time bases, hourly and monthly average hourly bases. An extensive database of horizontal solar irradiance from nine locations in Spain was used for the study. The data span through January 1980 to December 2012 of hourly solar irradiance for the nine locations and thus indicate a cumulative year sum of 132 years. This study first investigated the decomposition of the hourly horizontal irradiance into hourly direct and diffuse components using six decomposition models widely referenced in the bibliography. In the hourly decomposition investigation, it was observed that there are no significant differences between the six models for each specific location. Nevertheless, the performance of each of the models was strongly dependent on cloudiness conditions and the solar altitude at the location which is associated with the climatic condition of each site. Further investigations using the six decomposition models were conducted to estimate monthly average hourly values of direct and diffuse components of the solar irradiance with proper assessment of the different models' performance at various locations. Based on the results of the investigations which present no significant differences in the performance of the different models, an extremely simple algorithm was developed to estimate monthly average hourly values of direct and diffuse solar irradiance, which reduces the statistical errors in all locations investigated.Spanish Government (ENE2014-54601R) and the 506 Regional Government of Castile and Leon (BU358A12-2

Pedro de Alloylizen erretaula proiektua Mondragoeko San Agustin komenturako

 Same as in many other towns and villages in the Basque Country, the convent of St. Augustine in Mondragon was emptied and demolished during the 20th century. As a result of this action, the pieces of art guarded in the convent scattered around or even disappeared, casting them almost in complete oblivion. But we emphasize almost because we have discovered the sketch of the altarpiece made for the convent by the baroque architect and sculptor Pedro de Alloytiz, in the Historical Archive of Notary Records of Gipuzkoa. Thanks to this sketch, we now know that the image of St. Augustine that presides the convent of the same name in Hernani was originally in the convent in Mondragon.Euskal Herriko beste zenbait herritan gertatu den bezala, XX. mendean Mondragoen San Agustin komentua hustua eta eraitsia izan zen. Horren ondorioz, bertan gordetzen ziren artelanak desagertu edo sakabanatu ziren, horien memoria ia betiko galduz. Eta ia diogu, Gipuzkoako Protokoloen Artxibo Historikoan aurkitu baitugu Pedro de Alloytiz arkitekto eta eskultore barrokoak komentu horrentzako trazatutako San Agustinen erretaula. Horri esker, jakin izan dugu egun Hernaniko San Agustin komentuan ikus daitekeen San Agustinen eskulturaren jatorria Mondragoeko komentua zela

Garbancito

No publicado. Fecha tomada del código del documentoEsta Unidad Didáctica desarrolla un macrocentro de interés que tiene una temporalización de un trimestre. A través de doce fichas se busca que el niño desarrolle una serie de capacidades y destrezas: expresión plástico-oral y plástico-gráfica; pensamiento lógico y orientación espacio-temporal. Los objetivos generales son el desarrollo de la motricidad fina y el conocimiento del esquema corporal; conocimiento de los conceptos espaciales básicos; orientarse y actuar autónomamente en situaciones cotidianas; discriminación visual de errores; desarrollo del lenguaje oral mediante la discriminación de objetos; desarrollo de la grafomotricidad y de la noción de cantidad; desarrollo de la atención mediante el concocimiento de los colores; desarrollo de la discriminación auditiva y memoria y desarrollo de la expresión musical.Castilla y LeónES

The Isolation of Specialty Compounds from Amphidinium carterae Biomass by Two-Step Solid-Phase and Liquid-Liquid Extraction

The two main methods for partitioning crude methanolic extract from Amphidinium carterae biomass were compared. The objective was to obtain three enriched fractions containing amphidinols (APDs), carotenoids, and fatty acids. Since the most valuable bioproducts are APDs, their recovery was the principal goal. The first method consisted of a solid-phase extraction (SPE) in reverse phase that, for the first time, was optimized to fractionate organic methanolic extracts from Amphidinium carterae biomass using reverse-phase C18 as the adsorbent. The second method consisted of a two-step liquid-liquid extraction coupled with SPE and, alternatively, with solvent partitioning. The SPE method allowed the recovery of the biologically-active fraction (containing the APDs) by eluting with methanol (MeOH): water (H2O) (80:20 v/v). Alternatively, an APD purification strategy using solvent partitioning proved to be a better approach for providing APDs in a clear-cut way. When using n-butanol, APDs were obtained at a 70% concentration (w/w), whereas for the SPE method, the most concentrated fraction was only 18% (w/w). For the other fractions (carotenoids and fatty acids), a two-step liquid-liquid extraction (LLE) method coupled with the solvent partitioning method presented the best results

Feasibility of different cleaning methods for silver-copper alloys by X-ray fluorescence: application to ancient Greek silver coins

Archeological pieces with high Ag concentrations often have a surface enrichment of Ag. Usually, researchers in this field do not agree on the causes of these enrichments, one of which could be the cleaning procedures. In this work, a set of 18 ancient Greek silver coins was selected to study the effects of different cleaning procedures in terms of producing a surface Ag enrichment. The aim of this study is to find and select the less aggressive one in terms of the lower modification of Ag concentrations and visual aspect. These coins were analyzed by X-ray fluorescence (XRF) before and after each cleaning procedure

Subcutaneous anti-COVID-19 hyperimmune immunoglobulin for prevention of disease in asymptomatic individuals with SARS-CoV-2 infection: a double-blind, placebo-controlled, randomised clinical trialResearch in context

Summary: Background: Anti-COVID-19 hyperimmune immunoglobulin (hIG) can provide standardized and controlled antibody content. Data from controlled clinical trials using hIG for the prevention or treatment of COVID-19 outpatients have not been reported. We assessed the safety and efficacy of subcutaneous anti-COVID-19 hyperimmune immunoglobulin 20% (C19-IG20%) compared to placebo in preventing development of symptomatic COVID-19 in asymptomatic individuals with SARS-CoV-2 infection. Methods: We did a multicentre, randomized, double-blind, placebo-controlled trial, in asymptomatic unvaccinated adults (≥18 years of age) with confirmed SARS-CoV-2 infection within 5 days between April 28 and December 27, 2021. Participants were randomly assigned (1:1:1) to receive a blinded subcutaneous infusion of 10 mL with 1 g or 2 g of C19-IG20%, or an equivalent volume of saline as placebo. The primary endpoint was the proportion of participants who remained asymptomatic through day 14 after infusion. Secondary endpoints included the proportion of individuals who required oxygen supplementation, any medically attended visit, hospitalisation, or ICU, and viral load reduction and viral clearance in nasopharyngeal swabs. Safety was assessed as the proportion of patients with adverse events. The trial was terminated early due to a lack of potential benefit in the target population in a planned interim analysis conducted in December 2021. ClinicalTrials.gov registry: NCT04847141. Findings: 461 individuals (mean age 39.6 years [SD 12.8]) were randomized and received the intervention within a mean of 3.1 (SD 1.27) days from a positive SARS-CoV-2 test. In the prespecified modified intention-to-treat analysis that included only participants who received a subcutaneous infusion, the primary outcome occurred in 59.9% (91/152) of participants receiving 1 g C19-IG20%, 64.7% (99/153) receiving 2 g, and 63.5% (99/156) receiving placebo (difference in proportions 1 g C19-IG20% vs. placebo, −3.6%; 95% CI -14.6% to 7.3%, p = 0.53; 2 g C19-IG20% vs placebo, 1.1%; −9.6% to 11.9%, p = 0.85). None of the secondary clinical efficacy endpoints or virological endpoints were significantly different between study groups. Adverse event rate was similar between groups, and no severe or life-threatening adverse events related to investigational product infusion were reported. Interpretation: Our findings suggested that administration of subcutaneous human hyperimmune immunoglobulin C19-IG20% to asymptomatic individuals with SARS-CoV-2 infection was safe but did not prevent development of symptomatic COVID-19. Funding: Grifols