1,174 research outputs found

    Ultra-fast escape maneuver of an octopus-inspired robot

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    We design and test an octopus-inspired flexible hull robot that demonstrates outstanding fast-starting performance. The robot is hyper-inflated with water, and then rapidly deflates to expel the fluid so as to power the escape maneuver. Using this robot we verify for the first time in laboratory testing that rapid size-change can substantially reduce separation in bluff bodies traveling several body lengths, and recover fluid energy which can be employed to improve the propulsive performance. The robot is found to experience speeds over ten body lengths per second, exceeding that of a similarly propelled optimally streamlined rigid rocket. The peak net thrust force on the robot is more than 2.6 times that on an optimal rigid body performing the same maneuver, experimentally demonstrating large energy recovery and enabling acceleration greater than 14 body lengths per second squared. Finally, over 53% of the available energy is converted into payload kinetic energy, a performance that exceeds the estimated energy conversion efficiency of fast-starting fish. The Reynolds number based on final speed and robot length is Re700,000Re \approx 700,000. We use the experimental data to establish a fundamental deflation scaling parameter σ\sigma^* which characterizes the mechanisms of flow control via shape change. Based on this scaling parameter, we find that the fast-starting performance improves with increasing size.Comment: Submitted July 10th to Bioinspiration & Biomimetic

    Efficiency of Fish Propulsion

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    It is shown that the system efficiency of a self-propelled flexible body is ill-defined unless one considers the concept of quasi-propulsive efficiency, defined as the ratio of the power needed to tow a body in rigid-straight condition over the power it needs for self-propulsion, both measured for the same speed. Through examples we show that the quasi-propulsive efficiency is the only rational non-dimensional metric of the propulsive fitness of fish and fish-like mechanisms. Using two-dimensional viscous simulations and the concept of quasi-propulsive efficiency, we discuss the efficiency two-dimensional undulating foils. We show that low efficiencies, due to adverse body-propulsor hydrodynamic interactions, cannot be accounted for by the increase in friction drag

    The impact of uncertainty shocks on the volatility of commodity prices

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    In this paper, we empirically examine the impact of uncertainty shocks on the volatility of commodity prices. Using alternative measures of economic uncertainty for the U.S. we estimate their effects on commodity price volatility by employing both VAR and OLS regression models. We find that the unobservable economic uncertainty measures of Jurado et al. (2015) have a significant and long-lasting positive impact on the volatility of commodity prices. Our results indicate that a positive shock in both macroeconomic and financial uncertainty leads to a persistent increase in the volatility of the broad commodity market index and of the individual commodity prices, with the macroeconomic effect being more significant. The impact is stronger in energy commodities compared to the agricultural and metals markets. In addition, our findings show that the measure of unpredictability of the macroeconomic environment has the most significant impact on the commodity price volatility when compared to the observable measures of economic uncertainty that have a rather small and transitory effect. Finally, we show that uncertainty in the macroeconomy is significantly reduced after the occurrence of large commodity market volatility episodes

    Echo-Time and Field Strength Dependence of BOLD Reactivity in Veins and Parenchyma Using Flow-Normalized Hypercapnic Manipulation

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    While the BOLD (Blood Oxygenation Level Dependent) contrast mechanism has demonstrated excellent sensitivity to neuronal activation, its specificity with regards to differentiating vascular and parenchymal responses has been an area of ongoing concern. By inducing a global increase in Cerebral Blood Flow (CBF), we examined the effect of magnetic field strength and echo-time (TE) on the gradient-echo BOLD response in areas of cortical gray matter and in resolvable veins. In order to define a quantitative index of BOLD reactivity, we measured the percent BOLD response per unit fractional change in global gray matter CBF induced by inhaling carbon dioxide (CO[scubript 2]). By normalizing the BOLD response to the underlying CBF change and determining the BOLD response as a function of TE, we calculated the change in R[scubript 2]* (ΔR[scubript 2]*) per unit fractional flow change; the Flow Relaxation Coefficient, (FRC) for 3T and 1.5T in parenchymal and large vein compartments. The FRC in parenchymal voxels was 1.76±0.54 fold higher at 3T than at 1.5T and was 2.96±0.66 and 3.12±0.76 fold higher for veins than parenchyma at 1.5T and 3T respectively, showing a quantitative measure of the increase in specificity to parenchymal sources at 3T compared to 1.5T. Additionally, the results allow optimization of the TE to prioritize either maximum parenchymal BOLD response or maximum parenchymal specificity. Parenchymal signals peaked at TE values of 62.0±11.5 ms and 41.5±7.5 ms for 1.5T and 3T, respectively, while the response in the major veins peaked at shorter TE values; 41.0±6.9 ms and 21.5±1.0 ms for 1.5T and 3T. These experiments showed that at 3T, the BOLD CNR in parenchymal voxels exceeded that of 1.5T by a factor of 1.9±0.4 at the optimal TE for each field.National Institutes of Health (U.S.)National Center for Research Resources (U.S.)National Institutes of Health (U.S.) (P41 Regional Resource Grant P41RR14075)National Institutes of Health (U.S.) (P41 Regional Resource Grant RO1RR1453A01)Mental Illness and Neuroscience Discovery (MIND) InstituteNatural Sciences and Engineering Research Council of Canada (NSERC) (355583-2010)Canadian Institutes of Health Research (MOP 84378

    Added mass energy recovery of octopus-inspired shape change

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    Dynamic shape change of the octopus mantle during fast jet escape manoeuvres results in added mass energy recovery to the energetic advantage of the octopus, giving escape thrust and speed additional to that due to jetting alone. We show through numerical simulations and experimental validation of overall wake behaviour, that the success of the energy recovery is highly dependent on shrinking speed and Reynolds number, with secondary dependence on shape considerations and shrinking amplitude. The added mass energy recovery ratio η[subscript ma], which measures momentum recovery in relation to the maximum momentum recovery possible in an ideal flow, increases with increasing the non-dimensional shrinking parameter σ[superscript ∗]=ȧ[subscript max]/U√(Re[subscript 0]), where ȧ[subscript max] is the maximum shrinking speed, U is the characteristic flow velocity and √(Re0) is the Reynolds number at the beginning of the shrinking motion. An estimated threshold σ[superscript ∗]≈10 determines whether or not enough energy is recovered to the body to produce net thrust. Since there is a region of high transition for 10100 added mass energy is recovered at diminishing returns, we propose a design criterion for shrinking bodies to be in the range of 50<σ[superscript ∗]<100, resulting in 61–82 % energy recovery

    Shape of retracting foils that model morphing bodies controls shed energy and wake structure

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    The flow mechanisms of shape-changing moving bodies are investigated through the simple model of a foil that is rapidly retracted over a spanwise distance as it is towed at constant angle of attack. It is shown experimentally and through simulation that by altering the shape of the tip of the retracting foil, different shape-changing conditions may be reproduced, corresponding to: (i) a vanishing body, (ii) a deflating body and (iii) a melting body. A sharp-edge, ‘vanishing-like’ foil manifests strong energy release to the fluid; however, it is accompanied by an additional release of energy, resulting in the formation of a strong ring vortex at the sharp tip edges of the foil during the retracting motion. This additional energy release introduces complex and quickly evolving vortex structures. By contrast, a streamlined, ‘shrinking-like’ foil avoids generating the ring vortex, leaving a structurally simpler wake. The ‘shrinking’ foil also recovers a large part of the initial energy from the fluid, resulting in much weaker wake structures. Finally, a sharp edged but hollow, ‘melting-like’ foil provides an energetic wake while avoiding the generation of a vortex ring. As a result, a melting-like body forms a simple and highly energetic and stable wake, that entrains all of the original added mass fluid energy. The three conditions studied correspond to different modes of flow control employed by aquatic animals and birds, and encountered in disappearing bodies, such as rising bubbles undergoing phase change to fluid

    Hypoxia-inducible factor-1 (HIF-1) pathway activation by quercetin in human lens epithelial cells

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    Quercetin is a dietary bioflavonoid which has been shown to inhibit lens opacification in a number of models of cataract. The objectives of this study were to determine gene expression changes in human lens epithelial cells in response to quercetin and to investigate in detail the mechanisms underlying the responses. FHL-124 cells were treated with quercetin (10 µM) and changes in gene expression were measured by microarray. It was found that 65% of the genes with increased expression were regulated by the hypoxia-inducible factor-1 (HIF-1) pathway. Quercetin (10 and 30 µM) induced a time-dependent increase in HIF-1a protein levels. Quercetin (30 µM) was also responsible for a rapid and long-lasting translocation of HIF-1a from the cytoplasm to the nucleus. Activation of HIF-1 signaling by quercetin was confirmed by qRT–PCR which showed upregulation of the HIF-1 regulated genes EPO, VEGF, PGK1 and BNIP3. Analysis of medium taken from FHL-124 cells showed a sustained dose-dependent increase in VEGF secretion following quercetin treatment. The quercetin-induced increase and nuclear translocation of HIF-1a was reversed by addition of excess iron (100 µM). These results demonstrate that quercetin activates the HIF-1 signaling pathway in human lens epithelial cells

    Commodity price volatility and the economic uncertainty of pandemics

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    In this paper, we empirically investigate the impact of pandemics on commodity price volatility. In specific, we explore the impact of economic uncertainty related to global pandemics on the volatility of the SandP GSCI commodity index as well as on the sub-indexes of crude oil and gold. The results show that uncertainty related to pandemics have a strong negative impact on the volatility of commodity markets and especially on crude oil market, while the effect on gold market is positive but less significant. Our findings remain robust to a series of robustness checks

    What Drives False Memories in Psychopathology? A Case for Associative Activation

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    In clinical and court settings, it is imperative to know whether posttraumatic stress disorder (PTSD) and depression may make people susceptible to false memories. We conducted a review of the literature on false memory effects in participants with PTSD, a history of trauma, or depression. When emotional associative material was presented to these groups, their levels of false memory were raised relative to those in relevant comparison groups. This difference did not consistently emerge when neutral or nonassociative material was presented. Our conclusion is supported by a quantitative comparison of effect sizes between studies using emotional associative or neutral, nonassociative material. Our review suggests that individuals with PTSD, a history of trauma, or depression are at risk for producing false memories when they are exposed to information that is related to their knowledge base
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