Ovarian cyst impacted in the pouch of Douglas at 20 weeks' gestation managed by laparoscopic ovarian cystectomy: a case report

<p>Abstract</p> <p>Introduction</p> <p>The frequency of ovarian cysts in pregnancy is reported to be 1 in 1000 pregnancies. Laparoscopic ovarian cystectomy has been described in the literature as case series but this is the first case where an ovarian cyst at 20 weeks' gestation impacted in the pouch of Douglas was managed exclusively by laparoscopy.</p> <p>Case presentation</p> <p>A 31-year-old primigravida woman was diagnosed as having an 11 cm ovarian cyst at 20 weeks' gestation. At the 19th week routine ultrasound scan, the mass appeared to be cystic with no solid component. She was asymptomatic. In view of the size of the cyst, options were discussed with her including laparoscopic ovarian cystectomy which she agreed to. Laparoscopic surgery during pregnancy is reported to be safe and beneficial for pregnant women. At laparoscopy, a transvaginal scan was performed to localize the cyst and an ovarian cystectomy was carried out. The patient had an uneventful recovery and subsequent antenatal period. She had a lower segment caesarean section for non-progress of labour when both ovaries were found to be normal and mobile.</p> <p>Conclusions</p> <p>Laparoscopic surgery during pregnancy has numerous advantages compared to open laparotomy. This is a rare example of an ovarian cyst in the pouch of Douglas impacted behind the uterus which was managed by laparoscopy and shows the safety of the technique in the presence of an expert laparoscopic surgeon.</p

Effect of cowpea flour processing on the chemical properties and acceptability of a novel cowpea blended maize porridge

Childhood growth stunting is a pervasive problem in Malawi and is in large part due to low quality complementary foods and chronic gut inflammation. Introducing legumes such as cowpea (Vigna unguiculata) into the complementary diet has the potential to improve childhood growth by improving diet quality through improvements in macro- and micronutrients and also by reducing gut inflammation. However, cowpea is relatively underutilized in complementary feeding in Malawi due to its strong taste, long processing time, and high energy requirements for processing. Effective utilization of cowpea in complementary feeding requires processing which may affect chemical composition as well as sensory quality. The present study evaluated the effect of processing on the retention of zinc, crude fibre, and flavonoid in roasted, boiled, and dehulled cowpea flours, and assessed the acceptability of maize porridge (70%) enriched with one of the three cowpea flours (30%). Roasting, dehulling, and boiling did not have any effect on zinc content. Crude fibre content increased after processing by all methods. Processing had no effect on measurable flavonoids. Roasted, boiled, and dehulled cowpea blended maize porridges were acceptable to children with mean quantities of leftover food of less than 3g from the given 100g. Caregivers also rated the blended flours to be highly acceptable to them as well, with maize porridge blended with dehulled cowpea flour the most acceptable to both children and caregivers. These results demonstrate that cowpea flour, processed by any of these three different methods, could serve as a useful addition to maize porridge for complementary feeding of children in sub-Saharan Africa

Foreign students and community relations: A case study of the International Student Association, Cambridge, Massachusetts

Thesis (M.S.)--Boston Universit

The Effect of Misch Metal Additions on the Structure and Workability of Al-Mg (7-100/.) Alloys

ON the alloying elements used in aluminium alloys, copper was one of' the earliest employed commercially and for many years it has been the principal one. Aluminium-copper alloys to which manganese, magnesium or silicon has been added, belong to the important group generally known as "Duralumin". The binary alloys of aluminium with magnesium attra- cted the interest of investigators as early as 1900. There have been numerous attempts to utilise for general purposes alloys containing as Much as 10% magnesium ; alloys containing up to 30% magnesium have been used for special purposes

Barriers to Ethnic Minority and Women’s Enterprise:Existing Evidence, Policy Tensions and Unsettled Questions

This article presents an overarching review of the evidence regarding enterprise diversity. It discusses the context of ethnic minorities and women in enterprise and summarises research evidence relating to their relative access to finance, market selection and management skills. Policy within the field of diversity and enterprise is characterised by a number of tensions and unresolved questions including the presence of perceived or actual discrimination, the quantity and quality of ethnic minority and women-led businesses, potential market failure in the support provided to diverse enterprises and the substantive uniqueness of ethnic minority and women-led enterprises. Particular implications for policy and practice as well as directions for future research are discussed

Protein Kinase C Epsilon Overexpression in Prostate Adenocarcinoma is Associated with Oncogenesis

Background:&nbsp;PKCε, an isozyme of serine-threonine kinase, has been implicated in epithelial cancer metastasis and progression. This study investigates the impact of the oncogenic PKCε, overexpressed abnormally in human Prostate tumor samples and cell lines, to understand its efficacy. Methods: The microarray dataset, GSE86257, was processed for normalization. The identification of upregulated and downregulated genes was based on FDR &gt;1 and p &lt;0.05 values. Cytoscape analysis and functional enrichment of significant genes were done. The identified genes were validated on the TCGA dataset and survival analysis was performed by Kaplan-Meier analysis. Results: A total of 1524 DEGs were identified with 728 upregulated genes and 818 downregulated genes. The two significant modules with MCODE score:9.0 and Venn analysis provided cyclin-dependent kinase inhibitor protein (CDK1), Cyclin B1 (CCNB1), Phospholipase C Gamma 1 (PLCG1), Cyclin Dependent Kinase 9 (CDK9), Phosphoinositide-3-Kinase Regulatory Subunit 3 (PIK3R3), H4 Clustered Histone 6 (H4C6), Phospholipase C Gamma 2 (PLCG2) as most interacting genes. TCGA data analysis and Prognostic analysis revealed CCNBI, CDK9, and PLCG1 associated with poor prognosis. Conclusion:&nbsp;PKCε regulates genes that are responsible for cancer progression. Therefore, targeting PKCε in Prostate cancer may serve as an important regulatory effect and may improve the prognosis of the disease.&nbsp

Academics in pursuit of the part-time doctorate: Pressures and support issues associated with the career development of business and management academics

This article poses the question, how might the application of human resource development, career development (CD) and critical management studies perspectives cast light on the development of doctoral student? Nine part-time students took part in a longitudinal study that required them to complete monthly reflective reports or journals and participate in semi-structured interviews. Most of these part-time students are also in full-time employment as academics within ‘Post-1992' university employment in the United Kingdom. Post-1992 UK universities, also classified as ʼnew’ or ‘modern’ universities, comprised UK higher education institutions that were transformed from polytechnic institutions in or after 1992. Those part-time students within this study who are also in full-time employment as academics complained the lack of time for study has proved to be a significant hindrance and even a threat to their doctoral progress. From a critical management stance, it is proposed that power asymmetries exist between these students and the leaders of their employment organisations. These students are considered to be working towards CD within the turbulence of ʼnew’ universities, primarily in the strife for employment security. It is suggested that these concerns link with Grey’s (Grey, C. 1994) critical management perspective relating to ‘self-management’ as an example of labour process discipline. As such, this article offers a new perspective within CMS discourse, that of critical career development