A Small but Efficient Collaboration for the Spiral2 Control System Development

http://accelconf.web.cern.ch/AccelConf/ICALEPCS2013/papers/tucobab01.pdfThe Spiral2 radioactive ion beam facility to be commissioned in 2014 at Ganil (Caen) is built within international collaborations. This also concerns the control system development shared by three laboratories: Ganil has to coordinate the control and automated systems work packages, CEA/IRFU is in charge of the "injector" (sources and low energy beam lines) and the LLRF, CNRS/IPHC provides the emittancemeters and a beam diagnostics platform. Besides the technology Epics based, this collaboration, although being handled with a few people, nevertheless requires an appropriate and tight organization to reach the objectives given by the project. This contribution describes how, started in 2006, the collaboration for controls has been managed both from the technological point of view and the organizational one, taking into account not only the previous experience, technical background or skill of each partner, but also their existing working practices and "cultural" approaches. A first feedback comes from successful beam tests carried out at Saclay and Grenoble; a next challenge is the migration to operation, Ganil having to run Spiral2 as the other members are moving to new projects

Utility of Cardiac Magnetic Resonance to assess association between admission hyperglycemia and myocardial damage in patients with reperfused ST-Segment Elevation Myocardial Infarction

International audienceAbstract: Aims: to investigate the association between admission hyperglycemia and myocardial damage in patients with ST-segment elevation myocardial infarction (STEMI) using Cardiac Magnetic Resonance (CMR). Methods: We analyzed 113 patients with STEMI treated with successful primary percutaneous coronary intervention. Admission hyperglycemia was defined as a glucose level >= 7.8 mmol/l. Contrast-enhanced CMR was performed between 3 and 7 days after reperfusion to evaluate left ventricular function and perfusion data after injection of gadolinium-DTPA. First-pass images (FP), providing assessment of microvascular obstruction and Late Gadolinium Enhanced images (DE), reflecting the extent of infarction, were investigated and the extent of transmural tissue damage was determined by visual scores. Results: Patients with a supramedian FP and DE scores more frequently had left anterior descending culprit artery (p = 0.02 and < 0.001), multivessel disease (p = 0.02 for both) and hyperglycemia (p < 0.001). Moreover, they were characterized by higher levels of HbA(1c) (p = 0.01 and 0.04), peak plasma Creatine Kinase (p < 0.001), left ventricular end-systolic volume (p = 0.005 and < 0.001), and lower left ventricular ejection fraction (p = 0.001 and < 0.001). In a multivariate model, admission hyperglycemia remains independently associated with increased FP and DE scores. Conclusion: Our results show the existence of a strong relationship between glucose metabolism impairment and myocardial damage in patients with STEMI. Further studies are needed to show if aggressive glucose control improves myocardial perfusion, which could be assessed using CMR

Conceptual design of the AGATA 1π\pi array at GANIL

International audienceThe Advanced GAmma Tracking Array (AGATA) has been installed at the GANIL facility, Caen-France. This setup exploits the stable and radioactive heavy-ions beams delivered by the cyclotron accelerator complex of GANIL. Additionally, it benefits from a large palette of ancillary detectors and spectrometers to address in-beam gamma-ray spectroscopy of exotic nuclei. The set-up has been designed to couple AGATA with a magnetic spectrometer, charged-particle and neutron detectors, scintillators for the detection of high-energy gamma rays and other devices such as a plunger to measure nuclear lifetimes. In this paper, the design and the mechanical characteristics of the set-up are described. Based on simulations, expected performances of the AGATA l pi array are presente

Progress in the Design of the ASTERICS 28 GHz ECR Ion Source Superconducting Magnet for the NEWGAIN Project at GANIL

International audienceIn the framework of the NEWGAIN project (NEW GAnil INjector), a new injector is under development to supply the SPIRAL2 LINAC at GANIL with heavy ion of a mass to charge-state ratio up to A/q = 7. In order to produce this heavy ion beam, a superconducting 28 GHz ECR Ion Source called ASTERICS is under development and its superconducting magnet used for plasma confinement is designed at CEA in collaboration with LPSC and GANIL. The magnetic design of the ion source is based on the well-proved sextupole-in-solenoids configuration used in different laboratories worldwide. The superconducting coils will be in Nb-Ti placed in a He bath cooled by 6 in-situ cryocoolers. A magnetic and protection optimization has been done to meet the NEWGAIN requirements which calls for a bigger plasma chamber than the existing superconducting ECR ion sources while maintaining the same temperature margin in the coils. This paper focuses on the magnetic analysis, the protection studies and the choice of the superconducting conductor for the sextupole and the solenoids. To validate the coil fabrication steps and the assumptions made in the magnetic design, some winding trials have been done. Both simulations and mock-up results are presented here

Overview of the Iseult 11.7 T MRI Cryoplant Operation

International audienceThe Iseult whole-body MRI delivered its first images in October 2021. The masterpiece of this MRI is an actively shielded NbTi magnet providing a homogeneous magnetic field of 11.7 T within a 90 cm warm bore. A dedicated cryoplant was constructed to cool the magnet at 1.8 K using a superfluid helium bath and it is in nominal operation since March 2019. This paper will present the cryoplant design, as well as the connection of the cryogenic ancillary equipment with the magnet. Estimated thermal losses will be compared with experimental data collected since the beginning of the cooling phase. Then, we will describe the system maintenance and the periodic controls of the various pressurized components performed keeping the continuous nominal operation of the MRI. Finally, we will present the first lessons learned on this unique cryogenic system operation and possible options to improve its reliability

Status of the SPIRAL2 injector commissioning

International audienceThe SPIRAL2 injector, installed in its tunnel, is currently under commissioning at GANIL, Caen,France. The injector is composed of two low energy beam transport lines: one is dedicated tothe light ion beam production, the other to the heavy ions. The first light ion beam, created by a2.45 GHz electron cyclotron resonance ion source, has been successfully produced in December2014. The first beam of the PHOENIX V2 18 GHz heavy ion source was analyzed on 10 July2015. A status of the SPIRAL2 injector commissioning is given. An upgrade of the heavy ionsource, named PHOENIX V3 aimed to replace the V2, is presented. The new version features adoubled plasma chamber volume and the high charge state beam intensity is expected to increase bya factor of 1.5 to 2 up to the mass ∼50. A status of its assembly is proposed

Progress in the Design of the ASTERICS 28 GHz ECR Ion Source Superconducting Magnet for the NEWGAIN Project at GANIL

International audienceIn the framework of the NEWGAIN project (NEW GAnil INjector), a new injector is under development to supply the SPIRAL2 LINAC at GANIL with heavy ion of a mass to charge-state ratio up to A/q = 7. In order to produce this heavy ion beam, a superconducting 28 GHz ECR Ion Source called ASTERICS is under development and its superconducting magnet used for plasma confinement is designed at CEA in collaboration with LPSC and GANIL. The magnetic design of the ion source is based on the well-proved sextupole-in-solenoids configuration used in different laboratories worldwide. The superconducting coils will be in Nb-Ti placed in a He bath cooled by 6 in-situ cryocoolers. A magnetic and protection optimization has been done to meet the NEWGAIN requirements which calls for a bigger plasma chamber than the existing superconducting ECR ion sources while maintaining the same temperature margin in the coils. This paper focuses on the magnetic analysis, the protection studies and the choice of the superconducting conductor for the sextupole and the solenoids. To validate the coil fabrication steps and the assumptions made in the magnetic design, some winding trials have been done. Both simulations and mock-up results are presented here

ASTERICS, a new 28 GHz electron cyclotron resonance ion source for the SPIRAL2 accelerator

International audienceA new A/Q=7 injector is under development for the SPIRAL2 accelerator at Caen, France (NEWGAIN project). A new 28 GHz superconducting electron cyclotron resonance ion source named ASTERICS is under design for this project. The source features a modern cryostat and a large plasma chamber (91 mm radius and 600 mm length). The physical and technical motivations for a larger plasma volume are detailed and estimates of expected beam intensities enhancement are discussed. The source will mainly produce metallic ion beams: the concept of a temperature-controlled liner (up to 900°C) to stabilize high vapor pressure metal re-evaporation in the source is presented. The preliminary design of the ion source and its superconducting magnet are described

Recommandations françaises sur l’électroencéphalogramme [French guidelines on electroencephalogram]

National audienceElectroencephalography allows the functional analysis of electrical brain cortical activity and is the gold standard for analyzing electrophysiological processes involved in epilepsy but also in several other dysfunctions of the central nervous system. Morphological imaging yields complementary data, yet it cannot replace the essential functional analysis tool that is EEG. Furthermore, EEG has the great advantage of being non-invasive, easy to perform and allows control tests when follow-up is necessary, even at the patient's bedside. Faced with the advances in knowledge, techniques and indications, the Société de Neurophysiologie Clinique de Langue Française (SNCLF) and the Ligue Française Contre l'Épilepsie (LFCE) found it necessary to provide an update on EEG recommendations. This article will review the methodology applied to this work, refine the various topics detailed in the following chapters. It will go over the summary of recommendations for each of these chapters and underline proposals for writing an EEG report. Some questions could not be answered by the review of the literature; in those cases, an expert advice was given by the working and reading groups in addition to the guideline