Appendicular peritonitis in situs inversus totalis: a case report

<p>Abstract</p> <p>Introduction</p> <p><it>Situs inversus </it>is a congenital anomaly characterized by the transposition of the abdominal viscera. When associated with dextrocardia, it is known as <it>situs inversus totalis</it>. This condition is rare and can be a diagnostic problem when associated with appendicular peritonitis.</p> <p>Case presentation</p> <p>We report the case of a 20-year-old African man who presented to the emergency department with a 4-day history of diffuse abdominal pain, which began in his left iliac region and hypogastrium. After examination, we initiated a surgical exploration for peritonitis. We discovered a <it>situs inversus </it>at the left side of his liver, and his appendix was perforated in its middle third. A complementary post-operative thoracic and abdominal tomodensitometry revealed a <it>situs inversus totalis</it>.</p> <p>Conclusion</p> <p>Appendicular peritonitis in <it>situs inversus </it>is a rare association that can present a diagnostic problem. Morphologic exploration methods such as ultrasonography, tomodensitometry, magnetic resonance imaging, and laparoscopy may contribute to the early management of the disease and give guidance in choosing the most appropriate treatment for patients.</p

Water quality and immatures of the M and S forms of Anopheles gambiae s.s. and An. arabiensis in a Malian village

INTRODUCTION: The associations between the immatures of Anopheles gambiae s.s. (Diptera: Culicidae), its M and S forms, and Anopheles arabiensis among and within larval breeding habitats in Banambani, Mali were investigated under varying conditions of water quality and rainfall. The intent was to elucidate on niche partitioning of these taxa. METHODS: Immatures of An. arabiensis, An. gambiae s.s., and its M and S forms were sampled every alternate day for a month in mid-rainy season from three sampling sites in each of the larval breeding habitats (rock pools, swamp, and puddles). Water quality was characterized by alkalinity, conductivity, dissolved oxygen (D.O.), nitrate, orthophosphate, pH, temperature, total dissolved solids (TDS), and turbidity. A type 3 analysis of the GENMOD model was used to examine the associations between the proportional frequencies of young (first and second instar larvae) and old (third and fourth instar larvae and pupae) or total immatures of species or forms among sampling sites within and among larval breeding habitats during a category of rainfall as influenced by water quality. RESULTS: Of the 4,174 immatures sampled, 1,300 were molecularly identified to species and forms. Significant association between the proportional frequencies of young larvae of An. arabiensis, An. gambiae s.s., its M and S forms was found among sampling sites within habitats but not among larval breeding habitats. The proportional frequencies of young larvae of M and S forms varied daily perhaps due to recruitment, mortality, and dispersal within habitats. Conductivity and TDS had significant effects when the proportional frequencies of young larvae of M and S forms among sampling sites within habitats were significantly associated. Alkalinity, D.O., orthophosphate, pH, nitrate, temperature and turbidity had no effects on niche partitioning of species and forms among sampling sites within habitats. Rainfall did not affect the frequencies of these immatures. CONCLUSION: Conductivity and TDS have significant effects on niche partitioning of young larvae of M and S forms among sampling sites within habitats in Banambani, Mali

A rare case of anatomical variation of the femoral artery and vein

During a dissection of the two femoral trigons in a female corpse, about 14 years old, we discovered on the right side, the deep artery of the thigh arising from the medial side of the femoral artery and passed in front of the femoral vein above the mouth of the great saphenous vein; on both sides, there was the presence of a collateral canal which communicated the external iliac vein with the femoral vein on the right, on the left, it communicated the external iliac vein with the quadricipital vein. The lower part of the femoral vein was duplicated on both sides, but on the right, there was an interconnecting channel between the two trunks of the duplication. Variations of the femoral vessels are very frequent and can be responsible for an incident during the practice of certain gestures at the level of the femoral trigon such as: catheterization of the femoral artery or vein, the treatment of femoral hernias. Key words: Deep thigh artery, collateral venous canal, external iliac vein, anatomic variations

Physicochemical and Nutritional Properties of Varieties of Carrot (Daucus carota) grown in Region of Korhogo, North of Côte d’Ivoire

Very popular for its therapeutic and nutritional virtues, culture of carrot (Daucus carota) has developed in temperate zones of Asia and Europe but also in some tropical regions of Africa including Côte d'Ivoire. Agronomic factors, commercial and food requirements require selection of varieties with good nutritional values. In this study, physicochemical properties and nutritional values of four carrot varieties namely Amazonia, Bahia, Madona and Pamela+ were compared after cultivation and harvest in region of Korhogo. Results showed that, Amazonia, the control carrot variety stands out for its acidity and minerals levels. Bahia is the richest variety with high levels of carbohydrate and protein. Madona is the most basic, wettest and fatest carrot. For a long storage, Pamela is most interesting variety. To our knowledge, it is the first time that physicochemical and nutritional parameters of carrot varieties in region of Korhogo have been studied. Future research on these carrot varieties will be studied of their post-harvest conservation, their sensory analysis and their transformation

Dynamics of multiple insecticide resistance in the malaria vector Anopheles gambiae in a rice growing area in South-Western Burkina Faso

<p>Abstract</p> <p>Background</p> <p>Insecticide resistance of the main malaria vector, <it>Anopheles gambiae</it>, has been reported in south-western Burkina Faso, West Africa. Cross-resistance to DDT and pyrethroids was conferred by alterations at site of action in the sodium channel, the Leu-Phe <it>kdr </it>mutation; resistance to organophosphates and carbamates resulted from a single point mutation in the oxyanion hole of the acetylcholinesterase enzyme designed as <it>ace-1</it>^<it>R</it>.</p> <p>Methods</p> <p>An entomological survey was carried out during the rainy season of 2005 at Vallée du Kou, a rice growing area in south-western Burkina Faso. At the Vallée du Kou, both insecticide resistance mechanisms have been previously described in the M and S molecular forms of <it>An. gambiae</it>. This survey aimed i) to update the temporal dynamics and the circumsporozoite infection rate of the two molecular forms M and S of <it>An. gambiae </it>ii) to update the frequency of the Leu-Phe <it>kdr </it>mutation within these forms and finally iii) to investigate the occurrence of the <it>ace-1</it>^{<it>R </it>}mutation.</p> <p>Mosquitoes collected by indoor residual collection and by human landing catches were counted and morphologically identified. Species and molecular forms of <it>An. gambiae</it>, <it>ace-1</it>^{<it>R </it>}and Leu-Phe <it>kdr </it>mutations were determined using PCR techniques. The presence of the circumsporozoite protein of <it>Plasmodium falciparum </it>was determined using ELISA.</p> <p>Results</p> <p><it>Anopheles gambiae </it>populations were dominated by the M form. However the S form occurred in relative important proportion towards the end of the rainy season with a maximum peak in October at 51%. Sporozoite rates were similar in both forms. The frequency of the Leu-Phe <it>kdr </it>mutation in the S form reached a fixation level while it is still spreading in the M form. Furthermore, the <it>ace</it>-<it>1</it>^{<it>R </it>}mutation prevailed predominately in the S form and has just started spreading in the M form. The two mutations occurred concomitantly both in M and S populations.</p> <p>Conclusion</p> <p>These results showed that the Vallée du Kou, a rice growing area formerly occupied mainly by M susceptible populations, is progressively colonized by S resistant populations living in sympatry with the former. As a result, the distribution pattern of insecticide resistance mutations shows the occurrence of both resistance mechanisms concomitantly in the same populations. The impact of multiple resistance mechanisms in M and S populations of <it>An. gambiae </it>on vector control measures against malaria transmission, such as insecticide-treated nets (ITNs) and indoor residual spraying (IRS), in this area is discussed.</p

Evaluation and optimization of membrane feeding compared to direct feeding as an assay for infectivity

<p>Abstract</p> <p>Background</p> <p>Malaria parasite infectivity to mosquitoes has been measured in a variety of ways and setting, includind direct feeds of and/or membrane feeding blood collected from randomly selected or gametocytemic volunteers. <it>Anopheles gambiae s.l </it>is the main vector responsible of <it>Plasmodium falciparum </it>transmission in Bancoumana and represents about 90% of the laboratory findings, whereas <it>Plasmodium malariae </it>and <it>Plasmodium ovale </it>together represent only 10%.</p> <p>Materials and methods</p> <p>Between August 1996 and December 1998, direct and membrane feeding methods were compared for the infectivity of children and adolescent gametocyte carriers to anopheline mosquitoes in the village of Bancoumana in Mali. Gametocyte carriers were recruited twice a month through a screening of members of 30 families using Giemsa-stained thick blood smears. F1 generation mosquitoes issued from individual female wild mosquitoes from Bancoumana were reared in a controlled insectary conditions and fed 5% sugar solution in the laboratory in Bamako, until the feeding day when they are starved 12 hours before the feeding experiment. These F1 generation mosquitoes were divided in two groups, one group fed directly on gametocyte carriers and the other fed using membrane feeding method.</p> <p>Results</p> <p>Results from 372 <it>Plasmodium falciparum </it>gametocyte carriers showed that children aged 4–9 years were more infectious than adolescents (p = 0.039), especially during the rainy season. Data from 35 carriers showed that mosquitoes which were used for direct feeding were about 1.5 times more likely to feed (p < 0.001) and two times more likely to become infected, if they fed (p < 0.001), than were those which were used for membrane feeding. Overall, infectivity was about three-times higher for direct feeding than for membrane feeding (p < 0.001).</p> <p>Conclusion</p> <p>Although intensity of infectivity was lower for membrane feeding, it could be a surrogate to direct feeding for evaluating transmission-blocking activity of candidate malaria vaccines. An optimization of the method for future trials would involve using about three-times more mosquitoes than would be used for direct feeding.</p

Sensitivity study of the regional climate model RegCM4 to different convective schemes over West Africa

Abstract. The latest version of RegCM4 with CLM4.5 as a land surface scheme was used to assess the performance and sensitivity of the simulated West African climate system to different convection schemes. The sensitivity studies were performed over the West African domain from November 2002 to December 2004 at a spatial resolution of 50 km × 50 km and involved five convective schemes: (i) Emanuel; (ii) Grell; (iii) Emanuel over land and Grell over ocean (Mix1); (iv) Grell over land and Emanuel over ocean (Mix2); and (v) Tiedtke. All simulations were forced with ERA-Interim data. Validation of surface temperature at 2 m and precipitation were conducted using data from the Climate Research Unit (CRU), Global Precipitation Climatology Project (GPCP) and the Tropical Rainfall Measurement Mission (TRMM) during June to September (rainy season), while the simulated atmospheric dynamic was compared to ERA-Interim data. It is worth noting that the few previous similar sensitivity studies conducted in the region were performed using BATS as a land surface scheme and involved less convective schemes. Compared with the previous version of RegCM, RegCM4-CLM also shows a general cold bias over West Africa whatever the convective scheme used. This cold bias is more reduced when using the Emanuel convective scheme. In terms of precipitation, the dominant feature in model simulations is a dry bias that is better reduced when using the Emanuel convective scheme. Considering the good performance with respect to a quantitative evaluation of the temperature and precipitation simulations over the entire West African domain and its subregions, the Emanuel convective scheme is recommended for the study of the West African climate system

Internal supravesical hernia as a rare cauase of intestinal obstruction: a case report

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