29 research outputs found
Professional Behaviors and Fieldwork: A Curriculum Based Model in Occupational Therapy
Professional behaviors have been identified as imperative for fieldwork success in occupational therapy, and are held to high expectations by fieldwork educators. This study consisted of three phases. Phase one was a retrospective analysis of past Fieldwork Performance Evaluations (FWPE; n=319). Phase two consisted of the development of a curricular model and Level I Fieldwork Seminar with a focus on low-scoring professional behaviors on the FWPEs, which included verbal/ non-verbal communication, written communication, professional responsibility, work behaviors, and time management. Finally, phase three was a review of the course by the Philadelphia Region Fieldwork Consortium and edits to the seminar based on their feedback. Two theories, situated cognition and self-directed learning, were used to guide the curriculum development
Faint Infrared Flares from the Microquasar GRS 1915+105
We present simultaneous infrared and X-ray observations of the Galactic
microquasar GRS 1915+105 using the Palomar 5-m telescope and Rossi X-ray Timing
Explorer on July 10, 1998 UT. Over the course of 5 hours, we observed 6 faint
infrared (IR) flares with peak amplitudes of mJy and durations
of seconds. These flares are associated with X-ray
soft-dip/soft-flare cycles, as opposed to the brighter IR flares associated
with X-ray hard-dip/soft-flare cycles seen in August 1997 by Eikenberry et al.
(1998). Interestingly, the IR flares begin {\it before} the X-ray oscillations,
implying an ``outside-in'' origin of the IR/X-ray cycle. We also show that the
quasi-steady IR excess in August 1997 is due to the pile-up of similar faint
flares. We discuss the implications of this flaring behavior for understanding
jet formation in microquasars.Comment: 10 pages, 4 figures Accepted for publication in ApJ Letter
Gene expression differences in relation to age and social environment in queen and worker bumble bees
Eusocial insects provide special insights into the genetic pathways influencing aging because of their long-lived queens and flexible aging schedules. Using qRT-PCR in the primitively eusocial bumble bee Bombus terrestris (Linnaeus), we investigated expression levels of four candidate genes associated with taxonomically widespread age-related pathways (coenzyme Q biosynthesis protein 7, COQ7; DNA methyltransferase 3, Dnmt3; foraging, for; and vitellogenin, vg). In Experiment 1, we tested how expression changes with queen relative age and productivity. We found a significant age-related increase in COQ7 expression in queen ovary. In brain, all four genes showed higher expression with increasing female (queen plus worker) production, with this relationship strengthening as queen age increased, suggesting a link with the positive association of fecundity and longevity found in eusocial insect queens. In Experiment 2, we tested effects of relative age and social environment (worker removal) in foundress queens and effects of age and reproductive status in workers. In this experiment, workerless queens showed significantly higher for expression in brain, as predicted if downregulation of for is associated with the cessation of foraging by foundress queens following worker emergence. Workers showed a significant age-related increase in Dnmt3 expression in fat body, suggesting a novel association between aging and methylation in B. terrestris. Ovary activation was associated with significantly higher vg expression in fat body and, in younger workers, in brain, consistent with vitellogenin's ancestral role in regulating egg production. Overall, our findings reveal a mixture of novel and conserved features in age-related genetic pathways under primitive eusociality
KID Project:an internet-based digital video atlas of capsule endoscopy for research purposes
BACKGROUND AND AIMS:
Capsule endoscopy (CE) has revolutionized small-bowel (SB) investigation. Computational methods can enhance diagnostic yield (DY); however, incorporating machine learning algorithms (MLAs) into CE reading is difficult as large amounts of image annotations are required for training. Current databases lack graphic annotations of pathologies and cannot be used. A novel database, KID, aims to provide a reference for research and development of medical decision support systems (MDSS) for CE.
METHODS:
Open-source software was used for the KID database. Clinicians contribute anonymized, annotated CE images and videos. Graphic annotations are supported by an open-access annotation tool (Ratsnake). We detail an experiment based on the KID database, examining differences in SB lesion measurement between human readers and a MLA. The Jaccard Index (JI) was used to evaluate similarity between annotations by the MLA and human readers.
RESULTS:
The MLA performed best in measuring lymphangiectasias with a JI of 81\u200a\ub1\u200a6\u200a%. The other lesion types were: angioectasias (JI 64\u200a\ub1\u200a11\u200a%), aphthae (JI 64\u200a\ub1\u200a8\u200a%), chylous cysts (JI 70\u200a\ub1\u200a14\u200a%), polypoid lesions (JI 75\u200a\ub1\u200a21\u200a%), and ulcers (JI 56\u200a\ub1\u200a9\u200a%).
CONCLUSION:
MLA can perform as well as human readers in the measurement of SB angioectasias in white light (WL). Automated lesion measurement is therefore feasible. KID is currently the only open-source CE database developed specifically to aid development of MDSS. Our experiment demonstrates this potential
Building the Games Students Want to Play: BiblioBouts Project Interim Report #2
The University of Michigan’s School of Information and its partner, the Center for
History and New Media at George Mason University, are undertaking the 3-year
BiblioBouts Project (October 1, 2008 to September 30, 2011) to support the design,
development, testing, and evaluation of a computer game to teach incoming
undergraduate students information literacy skills and concepts. This second interim
report describes the project team’s 5-month progress achieving 2 of the project’s 4
objectives, designing the BiblioBouts game and engaging in evaluation activities. It also
enumerates major tasks that will occupy the team for the next 6 months. Appendixes A
and B describe the game’s design and include pedagogical goals and how the game
scores players.Institute of Museum and Library Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/64293/1/bbInterimReportToIMLS02.pd
Building the Games Students Want to Play: BiblioBouts Project Interim Report #3
The University of Michigan's School of Information and its partner, the Center for
History and New Media at George Mason University, are undertaking the 3-year
BiblioBouts Project (October 1, 2008 to September 30, 2011) to support the design,
development, testing, and evaluation of the web-based BiblioBouts game to teach
incoming undergraduate students information literacy skills and concepts. This third
interim report describes the BiblioBouts Project team’s 6-month progress achieving the project's 4 objectives: designing, developing, deploying, and evaluating the BiblioBouts game and recommending best practices for future information literacy games. This latest 6-month period was marked by extensive progress in the deployment and evaluation of the alpha version of BiblioBouts. Major tasks that will occupy the team for the next 6 months are applying evaluation findings to game redesign and enhancement. For general information about game design, pedagogical goals, scoring, game play, project participants, and playing BiblioBouts in your course, consult the BiblioBouts Project web site.Institute of Museum and Library Serviceshttp://deepblue.lib.umich.edu/bitstream/2027.42/69157/1/bbInterimReportToIMLS03.pd
Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome : Insights from the LUNG SAFE study
Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods: In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence of hyperoxemia (PaO2 > 100 mmHg) on day 1, sustained (i.e., present on day 1 and day 2) hyperoxemia, or excessive oxygen use (FIO2 ≥ 0.60 during hyperoxemia). Results: Of 2005 patients that met the inclusion criteria, 131 (6.5%) were hypoxemic (PaO2 < 55 mmHg), 607 (30%) had hyperoxemia on day 1, and 250 (12%) had sustained hyperoxemia. Excess FIO2 use occurred in 400 (66%) out of 607 patients with hyperoxemia. Excess FIO2 use decreased from day 1 to day 2 of ARDS, with most hyperoxemic patients on day 2 receiving relatively low FIO2. Multivariate analyses found no independent relationship between day 1 hyperoxemia, sustained hyperoxemia, or excess FIO2 use and adverse clinical outcomes. Mortality was 42% in patients with excess FIO2 use, compared to 39% in a propensity-matched sample of normoxemic (PaO2 55-100 mmHg) patients (P = 0.47). Conclusions: Hyperoxemia and excess oxygen use are both prevalent in early ARDS but are most often non-sustained. No relationship was found between hyperoxemia or excessive oxygen use and patient outcome in this cohort. Trial registration: LUNG-SAFE is registered with ClinicalTrials.gov, NCT02010073publishersversionPeer reviewe
Building the Games Students Want to Play: BiblioBouts Project Interim Report #4
The University of Michigan's School of Information and its partner, the Center for History and New Media at George Mason University, are undertaking the 3-year BiblioBouts Project (October 1, 2008 to September 30, 2011) to support the design, development, testing, and evaluation of the web-based BiblioBouts game to teach incoming undergraduate students information literacy skills and concepts. This fourth interim report describes the BiblioBouts Project team’s 5-month progress achieving the project’s 4 objectives: designing, developing, deploying, and evaluating the BiblioBouts game and recommending best practices for future information literacy games. This latest 5-month period was marked by extensive progress in the analysis of evaluation data from the testing of the alpha version of BiblioBouts and putting to work what was learned from this analysis in the design and development of the beta version of BiblioBouts. Major tasks that will occupy the team for the next 7 months are completing the development of beta BiblioBouts, pretesting BiblioBouts, testing BiblioBouts in classes at the five participating institutions, and evaluating test administrations. For general information about game design, pedagogical goals, scoring, game play, project participants, and playing BiblioBouts in your course, consult the BiblioBouts Project web site at http://bibliobouts.si.umich.edu/.Institute of Museum and Library Serviceshttp://deepblue.lib.umich.edu/bitstream/2027.42/78021/1/bbInterimReportToIMLS04.pd