Programmable time-multiplexed squeezed light source

One of the leading approaches to large-scale quantum information processing (QIP) is the continuous-variable (CV) scheme based on time multiplexing (TM). As a fundamental building block for this approach, quantum light sources to sequentially produce time-multiplexed squeezed-light pulses are required; however, conventional CV TM experiments have used fixed light sources that can only output the squeezed pulses with the same squeezing levels and phases. We here demonstrate a programmable time-multiplexed squeezed light source that can generate sequential squeezed pulses with various squeezing levels and phases at a time interval below 100 ns. The generation pattern can be arbitrarily chosen by software without changing its hardware configuration. This is enabled by using a waveguide optical parametric amplifier and modulating its continuous pump light. Our light source will implement various large-scale CV QIP tasks.Comment: 14 pages, 7 figure

Blood Rheology and Platelet Function in Untreated Early-Stage Essential Hypertensives Complicated with Metabolic Syndrome

We examined whether hemorheology and platelet function are affected in essential hypertensives (EHTs) of the World Health Organization stage I when complicated with metabolic syndrome (Mets). In 156 untreated EHTs, blood viscosity and platelet surface markers were determined. Blood viscosity was significantly elevated in 54 subjects with Mets compared with 102 subjects without Mets. Hematocrit and plasma viscosity increased in the group with Mets, although red blood cell rigidity index “k” did not differ between groups. As a whole group, blood viscosity correlated positively with hematocrit and plasma viscosity. Additionally, plasma viscosity correlated positively with plasma leptin, triglyceride, homeostasis model assessment index, C-reactive protein, and plasma fibrinogen, but negatively with high-density lipoprotein cholesterol. In contrast, no differences were seen in platelet surface markers between groups. In conclusion, EHTs of the early stage complicated with Mets are characterized by increased blood viscosity due to hemoconcentration and increased plasma viscosity

Clinical Study Blood Rheology and Platelet Function in Untreated Early-Stage Essential Hypertensives Complicated with Metabolic Syndrome

We examined whether hemorheology and platelet function are affected in essential hypertensives (EHTs) of the World Health Organization stage I when complicated with metabolic syndrome (Mets). In 156 untreated EHTs, blood viscosity and platelet surface markers were determined. Blood viscosity was significantly elevated in 54 subjects with Mets compared with 102 subjects without Mets. Hematocrit and plasma viscosity increased in the group with Mets, although red blood cell rigidity index "k" did not differ between groups. As a whole group, blood viscosity correlated positively with hematocrit and plasma viscosity. Additionally, plasma viscosity correlated positively with plasma leptin, triglyceride, homeostasis model assessment index, C-reactive protein, and plasma fibrinogen, but negatively with high-density lipoprotein cholesterol. In contrast, no differences were seen in platelet surface markers between groups. In conclusion, EHTs of the early stage complicated with Mets are characterized by increased blood viscosity due to hemoconcentration and increased plasma viscosity

キカンレンケイ ノ アセスメント ミズカラ ギャクタイ コウイ オ ウッタエテクル ハハオヤ エノ エンジョ

1990年以降、子育て期の母親の多くが、その時には子どもの虐待へリフレインする傾向があることがわかってきた。さらに顕在的に問題がない家庭の多くが危機的な状況にあることも明らかになった。子育て期における子供の虐待へリフレインする傾向のある母親やその家族へのサポート体制は現在も余りなく、また、実際進行している子供の虐待に対するフォーマルなサポートさえも少ない。そしてサポートされながらも、実際には長期的・継続的なケアが受けられていない。これらのことより、この増加し続ける可能性の高い子どもの虐待に対し、母親やその家族に対して、早期に発見し援助することがさらなる子どもの虐待を予防することになると考える。従って母親のニーズや問題を判断し、いかに適切な資源を送致して、危機を回避するかが重要となる。このことより、意思決定を最適なものにするために、アセスメント指標が必要となる。いかに有効なアセスメントが成し得たかにより援助者にとって、より望ましい援助となったかにつながる。本研究は電話相談にみるアセスメント指標作成プロセスおよびその段階での機能を有効に果たしたかを評価したものであり、予防支援を考察する場合の基礎的研究といえる

セイキョウイク ニ オケル CAI ノ サイヨウ ノ ココロミ

これまでにわれわれはCAI(Computer Assisted Instruction)を1.学習者のランクに合わせた提示ができる2.学習者の自己選択ができる3.自主学習ができる4.繰り返し学習ができるとし、効果的な教育方法の一つとして報告した。このCAIは様々な画面提示が大きな力を発揮することが可能である視覚的教材でもある。性教育においては多くの混乱とその解決案について試行錯誤がされており、視覚的に提示していくことの有効性が報告されている。そこで、CAIの採用が前述の利点によって効果があり、性の現状の解決方法の一つになると考え、"CAI性教育"コースウエアの開発、試行を行った。青少年を対象にコースウエア作成を行ったが、性の基礎的理解をねらいとしたため、内容は学童後期より活用できる内容とした。その具体的内容は人間学的性の理解を目指し、男女の性差と役割・男女交際と家族・生命誕生の3部構成とした。今回はこの性教育にどのような内容のコースウエアを作成したかを主眼とした

Prognostic Factors for Severe-to-Fatal Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis: A Multicenter Prospective Cohort Study

The prognostic factors associated with severe-to-fatal post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) remain unclear despite the extensive number of studies on PEP. In total, 3739 ERCP patients with biliary disease with an intact papilla and indicated for ERCP were prospectively enrolled at 36 centers from April 2017 to March 2018. Those with acute pancreatitis diagnosed before ERCP, altered gastrointestinal anatomy, and an American Society of Anesthesiologists (ASA) physical status > 4 were excluded. Univariate and multivariate logistic regression analyses were performed on patient-related factors, operator-related factors, procedure-related factors, and preventive measures to identify potential prognostic factors for severe-to-fatal PEP. Multivariate analyses revealed pancreatic guidewire-assisted biliary cannulation (OR 13.59, 95% CI 4.21–43.83, p p p = 0.015) as significant risk factors for severe-to-fatal PEP. Preventive measures included endoscopic biliary sphincterotomy (EST; OR 0.29, 95% CI, 0.11–0.79, p = 0.015) and prophylactic pancreatic stents (PPSs; OR 0.11, 95% CI, 0.01–0.87, p = 0.036). In biliary ERCP, pancreatic guidewire-assisted biliary cannulation, NSAID administration after ERCP, and previous pancreatitis were risk factors for severe-to-fatal PEP, whereas EST and PPS were significant preventive measures for severe-to-fatal PEP