88 research outputs found
Commensal observing with the Allen Telescope array: software command and control
The Allen Telescope Array (ATA) is a Large-Number-Small-Diameter radio
telescope array currently with 42 individual antennas and 5 independent
back-end science systems (2 imaging FX correlators and 3 time domain beam
formers) located at the Hat Creek Radio Observatory (HCRO). The goal of the ATA
is to run multiple back-ends simultaneously, supporting multiple science
projects commensally. The primary software control systems are based on a
combination of Java, JRuby and Ruby on Rails. The primary control API is
simplified to provide easy integration with new back-end systems while the
lower layers of the software stack are handled by a master observing system.
Scheduling observations for the ATA is based on finding a union between the
science needs of multiple projects and automatically determining an efficient
path to operating the various sub-components to meet those needs. When
completed, the ATA is expected to be a world-class radio telescope, combining
dedicated SETI projects with numerous radio astronomy science projects.Comment: SPIE Conference Proceedings, Software and Cyberinfrastructure for
Astronomy, Nicole M. Radziwill; Alan Bridger, Editors, 77400Z, Vol 774
Cytokines genotypes as predictors of disease outcomes in HIV-1 infected Ukrainians
У тезах представлені дані щодо асоціації поліморфізмів генів цитокінів з опортуністичними інфекціями у українців з ВІЛ-1.В тезисах представлены данные об ассоциации полиморфизмов генов цитокинов с оппортунистическими инфекциями у украинцев с ВИЧ-1.The data of cytokines genotypes association with outcomes of the disease in Ukrainians with HIV-1 were presented
The Allen Telescope Array: The First Widefield, Panchromatic, Snapshot Radio Camera for Radio Astronomy and SETI
The first 42 elements of the Allen Telescope Array (ATA-42) are beginning to
deliver data at the Hat Creek Radio Observatory in Northern California.
Scientists and engineers are actively exploiting all of the flexibility
designed into this innovative instrument for simultaneously conducting surveys
of the astrophysical sky and conducting searches for distant technological
civilizations. This paper summarizes the design elements of the ATA, the cost
savings made possible by the use of COTS components, and the cost/performance
trades that eventually enabled this first snapshot radio camera. The
fundamental scientific program of this new telescope is varied and exciting;
some of the first astronomical results will be discussed.Comment: Special Issue of Proceedings of the IEEE: "Advances in Radio
Telescopes", Baars,J. Thompson,R., D'Addario, L., eds, 2009, in pres
The Allen Telescope Array Pi GHz Sky Survey I. Survey Description and Static Catalog Results for the Bootes Field
The Pi GHz Sky Survey (PiGSS) is a key project of the Allen Telescope Array.
PiGSS is a 3.1 GHz survey of radio continuum emission in the extragalactic sky
with an emphasis on synoptic observations that measure the static and
time-variable properties of the sky. During the 2.5-year campaign, PiGSS will
twice observe ~250,000 radio sources in the 10,000 deg^2 region of the sky with
b > 30 deg to an rms sensitivity of ~1 mJy. Additionally, sub-regions of the
sky will be observed multiple times to characterize variability on time scales
of days to years. We present here observations of a 10 deg^2 region in the
Bootes constellation overlapping the NOAO Deep Wide Field Survey field. The
PiGSS image was constructed from 75 daily observations distributed over a
4-month period and has an rms flux density between 200 and 250 microJy. This
represents a deeper image by a factor of 4 to 8 than we will achieve over the
entire 10,000 deg^2. We provide flux densities, source sizes, and spectral
indices for the 425 sources detected in the image. We identify ~100$ new flat
spectrum radio sources; we project that when completed PiGSS will identify 10^4
flat spectrum sources. We identify one source that is a possible transient
radio source. This survey provides new limits on faint radio transients and
variables with characteristic durations of months.Comment: Accepted for publication in ApJ; revision submitted with extraneous
figure remove
Screen of Non-annotated Small Secreted Proteins of \u3ci\u3ePseudomonas syringae\u3c/i\u3e Reveals a Virulence Factor That Inhibits Tomato Immune Proteases
Pseudomonas syringae pv. tomato DC3000 (PtoDC3000) is an extracellular model plant pathogen, yet its potential to produce secreted effectors that manipulate the apoplast has been under investigated. Here we identified 131 candidate small, secreted, non-annotated proteins from the PtoDC3000 genome, most of which are common to Pseudomonas species and potentially expressed during apoplastic colonization. We produced 43 of these proteins through a custom-made gateway-compatible expression system for extracellular bacterial proteins, and screened them for their ability to inhibit the secreted immune protease C14 of tomato using competitive activity-based protein profiling. This screen revealed C14-inhibiting protein-1 (Cip1), which contains motifs of the chagasin-like protease inhibitors. Cip1 mutants are less virulent on tomato, demonstrating the importance of this effector in apoplastic immunity. Cip1 also inhibits immune protease Pip1, which is known to suppress PtoDC3000 infection, but has a lower affinity for its close homolog Rcr3, explaining why this protein is not recognized in tomato plants carrying the Cf-2 resistance gene, which uses Rcr3 as a co-receptor to detect pathogen-derived protease inhibitors. Thus, this approach uncovered a protease inhibitor of P. syringae, indicating that also P. syringae secretes effectors that selectively target apoplastic host proteases of tomato, similar to tomato pathogenic fungi, oomycetes and nematodes
The Allen Telescope Array Twenty-centimeter Survey - A 690-Square-Degree, 12-Epoch Radio Dataset - I: Catalog and Long-Duration Transient Statistics
We present the Allen Telescope Array Twenty-centimeter Survey (ATATS), a
multi-epoch (12 visits), 690 square degree radio image and catalog at 1.4GHz.
The survey is designed to detect rare, very bright transients as well as to
verify the capabilities of the ATA to form large mosaics. The combined image
using data from all 12 ATATS epochs has RMS noise sigma = 3.94mJy / beam and
dynamic range 180, with a circular beam of 150 arcsec FWHM. It contains 4408
sources to a limiting sensitivity of S = 20 mJy / beam. We compare the catalog
generated from this 12-epoch combined image to the NRAO VLA Sky Survey (NVSS),
a legacy survey at the same frequency, and find that we can measure source
positions to better than ~20 arcsec. For sources above the ATATS completeness
limit, the median flux density is 97% of the median value for matched NVSS
sources, indicative of an accurate overall flux calibration. We examine the
effects of source confusion due to the effects of differing resolution between
ATATS and NVSS on our ability to compare flux densities. We detect no
transients at flux densities greater than 40 mJy in comparison with NVSS, and
place a 2-sigma upper limit on the transient rate for such sources of 0.004 per
square degree. These results suggest that the > 1 Jy transients reported by
Matsumura et al. (2009) may not be true transients, but rather variable sources
at their flux density threshold.Comment: 41 pages, 19 figures, ApJ accepted; corrected minor typo in Table
Screen of Non-annotated Small Secreted Proteins of \u3ci\u3ePseudomonas syringae\u3c/i\u3e Reveals a Virulence Factor That Inhibits Tomato Immune Proteases
Pseudomonas syringae pv. tomato DC3000 (PtoDC3000) is an extracellular model plant pathogen, yet its potential to produce secreted effectors that manipulate the apoplast has been under investigated. Here we identified 131 candidate small, secreted, non-annotated proteins from the PtoDC3000 genome, most of which are common to Pseudomonas species and potentially expressed during apoplastic colonization. We produced 43 of these proteins through a custom-made gateway-compatible expression system for extracellular bacterial proteins, and screened them for their ability to inhibit the secreted immune protease C14 of tomato using competitive activity-based protein profiling. This screen revealed C14-inhibiting protein-1 (Cip1), which contains motifs of the chagasin-like protease inhibitors. Cip1 mutants are less virulent on tomato, demonstrating the importance of this effector in apoplastic immunity. Cip1 also inhibits immune protease Pip1, which is known to suppress PtoDC3000 infection, but has a lower affinity for its close homolog Rcr3, explaining why this protein is not recognized in tomato plants carrying the Cf-2 resistance gene, which uses Rcr3 as a co-receptor to detect pathogen-derived protease inhibitors. Thus, this approach uncovered a protease inhibitor of P. syringae, indicating that also P. syringae secretes effectors that selectively target apoplastic host proteases of tomato, similar to tomato pathogenic fungi, oomycetes and nematodes
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