657 research outputs found
Teaching writing to students from Asia: linking approach and motivation
This article is based on a study of the motivation and perceived outcomes of students from non-English speaking backgrounds enrolled in the English for Academic Study program at the Auckland University of Technology. It discusses the implications of the findings for tutors responsible for teaching writing. The findings indicate that that the motivation and immediate needs of those students are mainly instrumental, to write assignments and projects in a university environment, while the long-term goals are to use language in the workplace. For such students, we argue that a writing program will need to cater for generic forms acceptable to academic as well as real (often business) world readership. We also argue that while introducing an element of ideological critique is important when teaching writing, it does not seem to immediately help students with actual use or application of the genres relevant in real world situations. However, when considering long-term goals, the article looks at how the work of academic literacies thinkers can help alert students to power and ideological aspects of writing. The discussion in this article could also be generalized for the teaching of writing in ESL and EFL contexts
Premelting of Thin Wires
Recent work has raised considerable interest on the nature of thin metallic
wires. We have investigated the melting behavior of thin cylindrical Pb wires
with the axis along a (110) direction, using molecular dynamics and a
well-tested many-body potential. We find that---in analogy with cluster
melting---the melting temperature of a wire with radius is lower
than that of a bulk solid, , by . Surface melting
effects, with formation of a thin skin of highly diffusive atoms at the wire
surface, is observed. The diffusivity is lower where the wire surface has a
flat, local (111) orientation, and higher at (110) and (100) rounded areas. The
possible relevance to recent results on non-rupturing thin necks between an STM
tip and a warm surface is addressed.Comment: 10 pages, 4 postscript figures are appended, RevTeX, SISSA Ref.
131/94/CM/S
Preliminary findings of down-regulated genes in nasopharyngeal carcinoma
The cause and mechanism of nasopharyngeal carcinoma (NPC) progression are multifactorial and multigenic in nature. Despite the increasing number of genes found to be linked with NPC, the comprehensive list of associated genetic factors remains incomplete and the precise molecular pathways to this cancer are largely undefined. Here we show early evidence of possible association between several genes and the tumourigenesis of NPC. By employing the GeneFishingTM DEG Technique that allows the comparative analysis of expression profiles between normal and tumour nasopharyngeal biopsy tissues, we have identified 10 differentially expressed genes. These genes were down-regulated in tumours relative to normal control and have never been brought into the context of NPC tumourigenicity. Our findings represent preliminary yet novel clues of several associative genetic factors to neoplastic malignancy of the nasopharynx
The impact of social capital-based selection practices on talent management: evidence from telecom MNCs in Bangladesh
The purpose of this paper is to explore how social capital-based selection practices influence talent management (TM) in multinational companies (MNC). To date, little is known about this relationship. Empirical data were collected from 12 managers of three telecommunication firms in
Bangladesh using in-depth interviews. Our study found a significant influence of social capital-based selection practices on TM. We found that the relational
and cognitive dimensions of social capital were the major drivers of selection practices that influenced a talent search process. Trust and cultural norms within networking relationships affected TM through shared narratives, codes,
and language. Therefore, the role of existing human resource management (HRM) system for selection practices was found inadequate without the integration of social capital. For practical implications, upper-level managers
used social capital-based selection practices beyond HRM systems that were deemed pragmatic in selecting the right candidates for positions in organisations favouring intra-group homogeneity
Analysis towards the current management of limited common property in Malaysia
Strata properties in Malaysia were getting popular especially in the urban areas. As the population density in urban centres are expected to grow continuously, the number of residents for strata properties are expected to rise continuously which help to promote the mix-developments to be developed under a strata scheme. However, there are some issues regarding the unfair management for the common property in mixdevelopment where certain owners have to pay the maintenance fee for common properties which are not enjoyable by them. Therefore, this paper has the objective to examine the current practice of strata management towards limited common property. The enactment of Strata Management Act 2013 and enforcement in 2015 promoted the self-governance for strata scheme in Malaysia. For the current strata property, the scheme will be managed by all strata unit owners where Strata Title Act 1985 and Strata Management Act 2013 provide the framework in establishing the Management Corporation to administer and manage the strata scheme. MC is allowed to establish Subsidiary Management Corporation (Sub-MC) to manage limited common property and the designation of limited common property for different interest of parcel proprietors especially for mixdevelopment properties. Although the frameworks and procedures to establish the subsidiary management corporation were introduced under the Circular of JUPEM in 2017, however the number of establishment for Sub-MC is still low as there is only Sub-MC in Malaysia was proposed to be formed at 1 Mont’ Kiara mixed-use stratified development. Quantitative method and descriptive analysis were used in this research. Result shows that the management body has the knowledge in forming limited common property in their strata scheme. However, the low number in forming limited common property might due to problems in the procedure. Therefore, common pool resource theory was applied to describe the benefit in forming the limited common property
Breed-Specific Hematological Phenotypes in the Dog: A Natural Resource for the Genetic Dissection of Hematological Parameters in a Mammalian Species
Remarkably little has been published on hematological phenotypes of the domestic dog, the most polymorphic species on the planet. Information on the signalment and complete blood cell count of all dogs with normal red and white blood cell parameters judged by existing reference intervals was extracted from a veterinary database. Normal hematological profiles were available for 6046 dogs, 5447 of which also had machine platelet concentrations within the reference interval. Seventy-five pure breeds plus a mixed breed control group were represented by 10 or more dogs. All measured parameters except mean corpuscular hemoglobin concentration (MCHC) varied with age. Concentrations of white blood cells (WBCs), neutrophils, monocytes, lymphocytes, eosinophils and platelets, but not red blood cell parameters, all varied with sex. Neutering status had an impact on hemoglobin concentration, mean corpuscular hemoglobin (MCH), MCHC, and concentrations of WBCs, neutrophils, monocytes, lymphocytes and platelets. Principal component analysis of hematological data revealed 37 pure breeds with distinctive phenotypes. Furthermore, all hematological parameters except MCHC showed significant differences between specific individual breeds and the mixed breed group. Twenty-nine breeds had distinctive phenotypes when assessed in this way, of which 19 had already been identified by principal component analysis. Tentative breed-specific reference intervals were generated for breeds with a distinctive phenotype identified by comparative analysis. This study represents the first large-scale analysis of hematological phenotypes in the dog and underlines the important potential of this species in the elucidation of genetic determinants of hematological traits, triangulating phenotype, breed and genetic predisposition
A sleeping phantom leg awakened following hemicolectomy, thrombosis, and chemotherapy: a case report
INTRODUCTION: We describe the case of a patient who experienced phantom pain that began 42 years after right above-the-knee amputation. Immediately prior to phantom pain onset, this long-term amputee had experienced, in rapid succession, cancer, hemicolectomy, chemotherapy, and thrombotic occlusion. Very little has been published to date on the association between chemotherapy and exacerbation of neuropathic pain in amputees, let alone the phenomenon of bringing about pain in amputees who have been pain-free for many decades. While this patient presented with a unique profile following a rare sequence of medical events, his case should be recognized considering the frequent co-occurrence of osteomyelitis, chemotherapy, and amputation. CASE PRESENTATION: A 68-year-old Australian Caucasian man presented 42 years after right above-the-knee amputation with phantom pain immediately following hemicolectomy, thrombotic occlusion in the amputated leg, and chemotherapy treatment with leucovorin and 5-fluorouracil. He exhibited probable hyperalgesia with a reduced pinprick threshold and increased stump sensitivity, indicating likely peripheral and central sensitization. CONCLUSION: Our patient, who had long-term nerve injury due to amputation, together with recent ischemic nerve and tissue injury due to thrombosis, exhibited likely chemotherapy-induced neuropathy. While he presented with unique treatment needs, cases such as this one may actually be quite common considering that osteosarcoma can frequently lead to amputation and be followed by chemotherapy. The increased susceptibility of amputees to developing potentially intractable chemotherapy-induced neuropathic pain should be taken into consideration throughout the course of chemotherapy treatment. Patients in whom chronic phantom pain then develops, perhaps together with mobility issues, inevitably place greater demands on healthcare service providers that require treatment by various clinical specialists, including oncologists, neurologists, prosthetists, and, most frequently, general practitioners
Basin boundary, edge of chaos, and edge state in a two-dimensional model
In shear flows like pipe flow and plane Couette flow there is an extended
range of parameters where linearly stable laminar flow coexists with a
transient turbulent dynamics. When increasing the amplitude of a perturbation
on top of the laminar flow, one notes a a qualitative change in its lifetime,
from smoothly varying and short one on the laminar side to sensitively
dependent on initial conditions and long on the turbulent side. The point of
transition defines a point on the edge of chaos. Since it is defined via the
lifetimes, the edge of chaos can also be used in situations when the turbulence
is not persistent. It then generalises the concept of basin boundaries, which
separate two coexisting attractors, to cases where the dynamics on one side
shows transient chaos and almost all trajectories eventually end up on the
other side. In this paper we analyse a two-dimensional map which captures many
of the features identified in laboratory experiments and direct numerical
simulations of hydrodynamic flows. The analysis of the map shows that different
dynamical situations in the edge of chaos can be combined with different
dynamical situations in the turbulent region. Consequently, the model can be
used to develop and test further characterisations that are also applicable to
realistic flows.Comment: 24 pages, 9 color figure
PER2 Variation is Associated with Diurnal Preference in a Korean Young Population
The PER2 gene has been reported to influence diurnal preference. In this study, we have attempted to characterize the associations between the PER2 gene polymorphisms and diurnal preference in a population of healthy young subjects, controlling for the social and environmental confounding factors. Subjects were 299 students in a college, carefully selected to be mentally and physically healthy. All subjects completed the 13-item composite scale for morningness (CSM). PER2 gene polymorphisms were genotyped by PCR-based methods. Genotype and allele carrier status of a PER2 G3853A polymorphism (rs934945) were associated with CSM scores. Carriers of the 3853G allele showed significantly higher CSM scores (P = 0.004, P = 0.009, and P = 0.001; total, morningness, and activity plan, respectively). There were no significant differences on CSM scores among genotypes and allele status of PER2 rs2304672. This result indicates that rs934945 of PER2 may be associated with diurnal preference in a Korean healthy population
Initial Sequence and Comparative Analysis of the Cat Genome
The genome sequence (1.9-fold coverage) of an inbred Abyssinian domestic cat was assembled, mapped, and annotated with a comparative approach that involved cross-reference to annotated genome assemblies of six mammals (human, chimpanzee, mouse, rat, dog, and cow). The results resolved chromosomal positions for 663,480 contigs, 20,285 putative feline gene orthologs, and 133,499 conserved sequence blocks (CSBs). Additional annotated features include repetitive elements, endogenous retroviral sequences, nuclear mitochondrial (numt) sequences, micro-RNAs, and evolutionary breakpoints that suggest historic balancing of translocation and inversion incidences in distinct mammalian lineages. Large numbers of single nucleotide polymorphisms (SNPs), deletion insertion polymorphisms (DIPs), and short tandem repeats (STRs), suitable for linkage or association studies were characterized in the context of long stretches of chromosome homozygosity. In spite of the light coverage capturing ∼65% of euchromatin sequence from the cat genome, these comparative insights shed new light on the tempo and mode of gene/genome evolution in mammals, promise several research applications for the cat, and also illustrate that a comparative approach using more deeply covered mammals provides an informative, preliminary annotation of a light (1.9-fold) coverage mammal genome sequence
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