701 research outputs found

    Superconducting Fluctuation Corrections to the Thermal Current in Granular Metals

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    The first-order superconducting fluctuation corrections to the thermal conductivity of a granular metal are calculated. A suppression of thermal conductivity proportional to Tc/(T−Tc)T_c/(T-T_c) is observed in a region not too close to the critical temperature TcT_c. As T≃TcT\simeq T_c, a saturation of the correction is found, and its sign depends on the ratio between the barrier transparency and the critical temperature. In both regimes, the Wiedemann-Franz law is violated.Comment: 9 pages, 7 figures. Replaced with published version. Important change

    Weak localization effects in granular metals

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    The weak localization correction to the conductivity of a granular metal is calculated using the diagrammatic technique in the reciprocal grain lattice representation. The properties of this correction are very similar to that one in disordered metal, with the replacement of the electron mean free path ℓ\ell by the grain diameter dd and the dimensionless conductance gg by the tunnelling dimensionless conductance gTg_{T}. In particular, we demonstrate that at zero temperature no conducting phase can exist for dimensions D≤2D\leq 2. We also analyze the WL correction to magnetoconductivity in the weak field limit.Comment: 4 pages, 3 figures; minor corrections adde

    Changes in leaf size and in the rate of leaf production contribute to cytokinin-mediated growth promotion in Epipremnum aureum L. cuttings

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    The growth of ornamental foliage plants is often limited by pot size, which exerts a restriction on root growth and, therefore, on the production of root-synthesised cytokinins which play key regulatory roles in the development and growth of the shoot. We studied the effect of exogenous 6-benzylaminopurine (BAP) on plant growth and on the development of leaf area in Epipremnum aureum L. plants grown in pots. The hypothesis was that increasing the concentration of shoot cytokinins by foliar spraying of BAP would promote plant growth by overcoming the effects of root restriction on whole plant development. Three glasshouse experiments were conducted using (i) different concentrations of BAP, (ii) different numbers of spray applications, and (iii) different light environments. The results showed that a single spray application of BAP at 5 mg l–1 significantly (P ≤ 0.05) increased leaf area (by 20 – 40%) and biomass [fresh weight (FW)] accumulation (by 30 – 35%), while higher BAP concentrations, or repeated spray applications had less effect. The maximum effect of BAP was observed under intermediate levels of irradiance. The increased development of leaf area in BAP-sprayed plants resulted from increases in both individual average leaf areas (by 100 – 150% cf. the controls) and the rate of leaf initiation (by 30 – 120% cf. the controls). The latter could be attributed to a shortening of the phyllochron, since no branching was observed under any BAP spray treatment. Alternative physiological explanations, as well as possible commercial applications of these BAP-elicited responses are discussed.Fil: Di Benedetto, A.. Universidad de Buenos Aires. Facultad de Agronomia; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; ArgentinaFil: Galmarini, Claudio Romulo. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Cuyo Mendoza-san Juan. Estación Experimental Agropecuaria la Consulta; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mendoza; ArgentinaFil: Tognetti, J.. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentin

    Fenología, producción y conservación post cosecha de diferentes cultivares de cebolla en el sudeste de Buenos Aires

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    p.73-80Los cultivos de cebolla en el S.E. de la Provincia de Buenos Aires se realizan casi exclusivamente con el cultivar Valcatorce INTA. Aunque se ha propuesto el cultivo de cebollas de ciclo más corto, prácticamente no existe información acerca del comportamiento de estos cultivares en la región. En este trabajo se evalúa la fenología, producción y comportamiento postcosecha de seis cultivares de diferente longitud de ciclo, en comparación con Valcatorce. De acuerdo a nuestros ensayos, el empleo de los genotipos de ciclo corto evaluados sólo sería factible para consumo inmediato, debido a su mala conservación. Por otra parte, Valcatorce presentó la mejor conservación y una producción aceptable, mientras que Armada se destacó como una interesante alternativa. Se evalúan, asimismo, diferentes parámetros como indicadores de la longevidad post-cosecha

    Spectral shapes of solid neon

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    We present a Path Integral Monte Carlo calculation of the first three moments of the displacement-displacement correlation functions of solid neon at different temperatures for longitudinal and transverse phonon modes. The Lennard-Jones potential is considered. The relevance of the quantum effects on the frequency position of the peak and principally on the line-width of the spectral shape is clearly pointed out. The spectrum is reconstructed via a continued fraction expansion; the approximations introduced using the effective potential quantum molecular dynamics are discussed.Comment: 3 pages, 2 figures, 3 table

    Anisotropy and Ising-like transition of the S=5/2 two-dimensional Heisenberg antiferromagnet Mn-formate di-Urea

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    Recently reported measurements of specific heat on the compound Mn-formate di-Urea (Mn-f-2U) by Takeda et al. [Phys. Rev. B 63, 024425 (2001)] are considered. As a model to describe the overall thermodynamic behavior of such compound, the easy-axis two-dimensional Heisenberg antiferromagnet is proposed and studied by means of the 'pure quantum self-consistent harmonic approximation' (PQSCHA). In particular it is shown that, when the temperature decreases, the compound exhibits a crossover from 2D-Heisenberg to 2D-Ising behavior, followed by a 2D-Ising-like phase transition, whose location allows to get a reliable estimate of the easy-axis anisotropy driving the transition itself. Below the critical temperature T_N=3.77 K, the specific heat is well described by the two-dimensional easy-axis model down to a temperature T*=1.47 K where a T^3-law sets in, possibly marking a low-temperature crossover of magnetic fluctuations from two to three dimensions.Comment: 3 pages, 2 figures, 47th Annual Conference on Magnetism and Magnetic Materials (Tampa, FL, USA, 11-15/11/2002

    Heisenberg antiferromagnet on the square lattice for S>=1

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    Theoretical predictions of a semiclassical method - the pure-quantum self-consistent harmonic approximation - for the correlation length and staggered susceptibility of the Heisenberg antiferromagnet on the square lattice (2DQHAF) agree very well with recent quantum Monte Carlo data for S=1, as well as with experimental data for the S=5/2 compounds Rb2MnF4 and KFeF4. The theory is parameter-free and can be used to estimate the exchange coupling: for KFeF4 we find J=2.33 +- 0.33 meV, matching with previous determinations. On this basis, the adequacy of the quantum nonlinear sigma model approach in describing the 2DQHAF when S>=1 is discussed.Comment: 4 pages RevTeX file with 5 figures included by psfi

    Line-field confocal optical coherence tomography: a new tool for non-invasive differential diagnosis of pustular skin disorders

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    Background The spectrum of pustular skin disorders (PSD) is large and particularly challenging, including inflammatory, infectious and amicrobial diseases. Moreover, although pustules represent the unifying clinical feature, they can be absent or not fully developed in the early stage of the disease. The line-field confocal optical coherence tomography (LC-OCT) is a recently developed imaging technique able to perform a non-invasive, in vivo, examination of the epidermis and upper dermis, reaching very high image resolution and virtual histology. Objectives We aimed to investigate the potentialities of LC-OCT in the non-invasive differential diagnosis of a series of 11 PSD with different aetiology, microscopic features, body location and incidence rates. Materials and Methods Complete LC-OCT imaging (i.e. 2D/3D frames, videos) was performed on a total of 19 patients (10 females and 9 males) aged between 35 and 79 years. Images were blindly evaluated and compared with corresponding histopathologic findings. Results The LC-OCT imaging was able to detect with high accuracy the pustule structure including shape, margins, morphology and cellular content, along with peculiar epidermal and adnexal alterations in each condition, including: Acute Generalized Exanthematous Pustulosis, Generalized pustular psoriasis, Generalized pustular figurate erythema, Subcorneal Pustular Dermatosis, Intraepidermal IgA pustulosis, Palmoplantar pustulosis, Palmoplantar pustular psoriasis. Herpetic whitlow, Acrodermatitis continua of Hallopeau, Vesicopustular Sweet syndrome and Vesicopustular Eosinophilic cellulitis, with pustular appearance, were also compared. Conclusions The new LC-OCT can represent a rapid, non-invasive and painless tool which can help differentiating among PSD of different aetiology and microscopic morphology in clinical mimickers in daily practice

    Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and function

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    Eukaryotic cells license each DNA replication origin during G1 phase by assembling a prereplication complex that contains a Mcm2-7 (minichromosome maintenance proteins 2-7) double hexamer. During S phase, each Mcm2-7 hexamer forms the core of a replicative DNA helicase. However, the mechanisms of origin licensing and helicase activation are poorly understood. The helicase loaders ORC-Cdc6 function to recruit a single Cdt1-Mcm2-7 heptamer to replication origins prior to Cdt1 release and ORC-Cdc6-Mcm2-7 complex formation, but how the second Mcm2-7 hexamer is recruited to promote double-hexamer formation is not well understood. Here, structural evidence for intermediates consisting of an ORC-Cdc6-Mcm2-7 complex and an ORC-Cdc6-Mcm2-7-Mcm2-7 complex are reported, which together provide new insights into DNA licensing. Detailed structural analysis of the loaded Mcm2-7 double-hexamer complex demonstrates that the two hexamers are interlocked and misaligned along the DNA axis and lack ATP hydrolysis activity that is essential for DNA helicase activity. Moreover, we show that the head-to-head juxtaposition of the Mcm2-7 double hexamer generates a new protein interaction surface that creates a multisubunit-binding site for an S-phase protein kinase that is known to activate DNA replication. The data suggest how the double hexamer is assembled and how helicase activity is regulated during DNA licensing, with implications for cell cycle control of DNA replication and genome stability

    A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNA.

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    The regulated loading of the replicative helicase minichromosome maintenance proteins 2–7 (MCM2–7) onto replication origins is a prerequisite for replication fork establishment and genomic stability. Origin recognition complex (ORC), Cdc6, and Cdt1 assemble two MCM2–7 hexamers into one double hexamer around dsDNA. Although the MCM2–7 hexamer can adopt a ring shape with a gap between Mcm2 and Mcm5, it is unknown which Mcm interface functions as the DNA entry gate during regulated helicase loading. Here, we establish that the Saccharomyces cerevisiae MCM2–7 hexamer assumes a closed ring structure, suggesting that helicase loading requires active ring opening. Using a chemical biology approach, we show that ORC–Cdc6–Cdt1-dependent helicase loading occurs through a unique DNA entry gate comprised of the Mcm2 and Mcm5 subunits. Controlled inhibition of DNA insertion triggers ATPase-driven complex disassembly in vitro, while in vivo analysis establishes that Mcm2/Mcm5 gate opening is essential for both helicase loading onto chromatin and cell cycle progression. Importantly, we demonstrate that the MCM2–7 helicase becomes loaded onto DNA as a single hexamer during ORC/Cdc6/Cdt1/MCM2–7 complex formation prior to MCM2–7 double hexamer formation. Our study establishes the existence of a unique DNA entry gate for regulated helicase loading, revealing key mechanisms in helicase loading, which has important implications for helicase activation
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