4,719 research outputs found

    Explanations of Emigration From Grenada, West Indies

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    Paper by Peter M. Tobia

    Fixation in finite populations evolving in fluctuating environments

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    The environment in which a population evolves can have a crucial impact on selection. We study evolutionary dynamics in finite populations of fixed size in a changing environment. The population dynamics are driven by birth and death events. The rates of these events may vary in time depending on the state of the environment, which follows an independent Markov process. We develop a general theory for the fixation probability of a mutant in a population of wild-types, and for mean unconditional and conditional fixation times. We apply our theory to evolutionary games for which the payoff structure varies in time. The mutant can exploit the environmental noise; a dynamic environment that switches between two states can lead to a probability of fixation that is higher than in any of the individual environmental states. We provide an intuitive interpretation of this surprising effect. We also investigate stationary distributions when mutations are present in the dynamics. In this regime, we find two approximations of the stationary measure. One works well for rapid switching, the other for slowly fluctuating environments

    OpSeF : Open Source Python Framework for Collaborative Instance Segmentation of Bioimages

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    Various pre-trained deep learning models for the segmentation of bioimages have been made available as developer-to-end-user solutions. They are optimized for ease of use and usually require neither knowledge of machine learning nor coding skills. However, individually testing these tools is tedious and success is uncertain. Here, we present the Open Segmentation Framework (OpSeF), a Python framework for deep learning-based instance segmentation. OpSeF aims at facilitating the collaboration of biomedical users with experienced image analysts. It builds on the analysts' knowledge in Python, machine learning, and workflow design to solve complex analysis tasks at any scale in a reproducible, well-documented way. OpSeF defines standard inputs and outputs, thereby facilitating modular workflow design and interoperability with other software. Users play an important role in problem definition, quality control, and manual refinement of results. OpSeF semi-automates preprocessing, convolutional neural network (CNN)-based segmentation in 2D or 3D, and postprocessing. It facilitates benchmarking of multiple models in parallel. OpSeF streamlines the optimization of parameters for pre- and postprocessing such, that an available model may frequently be used without retraining. Even if sufficiently good results are not achievable with this approach, intermediate results can inform the analysts in the selection of the most promising CNN-architecture in which the biomedical user might invest the effort of manually labeling training data. We provide Jupyter notebooks that document sample workflows based on various image collections. Analysts may find these notebooks useful to illustrate common segmentation challenges, as they prepare the advanced user for gradually taking over some of their tasks and completing their projects independently. The notebooks may also be used to explore the analysis options available within OpSeF in an interactive way and to document and share final workflows. Currently, three mechanistically distinct CNN-based segmentation methods, the U-Net implementation used in Cellprofiler 3.0, StarDist, and Cellpose have been integrated within OpSeF. The addition of new networks requires little; the addition of new models requires no coding skills. Thus, OpSeF might soon become both an interactive model repository, in which pre-trained models might be shared, evaluated, and reused with ease.Peer reviewe

    Regional Cultures and the Psychological Geography of Switzerland: Person-Environment-Fit in Personality Predicts Subjective Wellbeing.

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    The present study extended traditional nation-based research on person-culture-fit to the regional level. First, we examined the geographical distribution of Big Five personality traits in Switzerland. Across the 26 Swiss cantons, unique patterns were observed for all traits. For Extraversion and Neuroticism clear language divides emerged between the French- and Italian-speaking South-West vs. the German-speaking North-East. Second, multilevel modeling demonstrated that person-environment-fit in Big Five, composed of elevation (i.e., mean differences between individual profile and cantonal profile), scatter (differences in mean variances) and shape (Pearson correlations between individual and cantonal profiles across all traits; Furr, 2008, 2010), predicted the development of subjective wellbeing (i.e., life satisfaction, satisfaction with personal relationships, positive affect, negative affect) over a period of 4 years. Unexpectedly, while the effects of shape were in line with the person-environment-fit hypothesis (better fit predicted higher subjective wellbeing), the effects of scatter showed the opposite pattern, while null findings were observed for elevation. Across a series of robustness checks, the patterns for shape and elevation were consistently replicated. While that was mostly the case for scatter as well, the effects of scatter appeared to be somewhat less robust and more sensitive to the specific way fit was modeled when predicting certain outcomes (negative affect, positive affect). Distinguishing between supplementary and complementary fit may help to reconcile these findings and future research should explore whether and if so under which conditions these concepts may be applicable to the respective facets of person-culture-fit

    In--out intermittency in PDE and ODE models

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    We find concrete evidence for a recently discovered form of intermittency, referred to as in--out intermittency, in both PDE and ODE models of mean field dynamos. This type of intermittency (introduced in Ashwin et al 1999) occurs in systems with invariant submanifolds and, as opposed to on--off intermittency which can also occur in skew product systems, it requires an absence of skew product structure. By this we mean that the dynamics on the attractor intermittent to the invariant manifold cannot be expressed simply as the dynamics on the invariant subspace forcing the transverse dynamics; the transverse dynamics will alter that tangential to the invariant subspace when one is far enough away from the invariant manifold. Since general systems with invariant submanifolds are not likely to have skew product structure, this type of behaviour may be of physical relevance in a variety of dynamical settings. The models employed here to demonstrate in--out intermittency are axisymmetric mean--field dynamo models which are often used to study the observed large scale magnetic variability in the Sun and solar-type stars. The occurrence of this type of intermittency in such models may be of interest in understanding some aspects of such variabilities.Comment: To be published in Chaos, June 2001, also available at http://www.eurico.web.co

    Can Self-Tracking Solutions Help with Understanding Quality of Smart, Connected Products?

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    Smart connected products (SCPs) have gained significant attention in different domains because they offer numerous benefits and change the form of competition and value creation. While quality is im-portant for SCPs, no holistic quality model is available to target the present quality problems. Further-more, since the concept of an SCP is quite abstract, a bottom-up approach that starts with a concrete example seems suitable. Therefore, this paper identifies the five key components of SCPs and maps them to self-tracking solutions (STS) in order to show that STSs are appropriate examples. We also analyse quality models in corresponding areas to verify the absence of a holistic quality model for the selected example. This contribution identifies the research gap regarding holistic, stakeholder-oriented quality models and helps researchers understand SCPs better

    Single-photon emission at a rate of 143 MHz from a deterministic quantum-dot microlens triggered by a mode-locked vertical-external-cavity surface-emitting laser

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    This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Appl. Phys. Lett. 107, 041105 (2015) and may be found at https://doi.org/10.1063/1.4927429.We report on the realization of a quantum dot (QD) based single-photon source with a record-high single-photon emission rate. The quantum light source consists of an InGaAs QD which is deterministically integrated within a monolithic microlens with a distributed Bragg reflector as back-side mirror, which is triggered using the frequency-doubled emission of a mode-locked vertical-external-cavity surface-emitting laser (ML-VECSEL). The utilized compact and stable laser system allows us to excite the single-QD microlens at a wavelength of 508 nm with a pulse repetition rate close to 500 MHz at a pulse width of 4.2 ps. Probing the photon statistics of the emission from a single QD state at saturation, we demonstrate single-photon emission of the QD-microlens chip with g(2)(0) < 0.03 at a record-high single-photon flux of (143 ± 16) MHz collected by the first lens of the detection system. Our approach is fully compatible with resonant excitation schemes using wavelength tunable ML-VECSELs, which will optimize the quantum optical properties of the single-photon emission in terms of photon indistinguishability.BMBF, 03V0630, Entwicklung einer Halbleiterbasierten Einzelphotonenquelle für die Quanteninformationstechnologie (QSOURCE)DFG, 43659573, SFB 787: Halbleiter - Nanophotonik: Materialien, Modelle, BauelementeDFG, 192635911, GRK 1782: Funktionalisierung von HalbleiternDFG, 223848855, SFB 1083: Struktur und Dynamik innerer Grenzfläche

    Tuning the mobility of a driven Bose-Einstein condensate via diabatic Floquet bands

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    We study the response of ultracold atoms to a weak force in the presence of a temporally strongly modulated optical lattice potential. It is experimentally demonstrated that the strong ac-driving allows for a tailoring of the mobility of a dilute atomic Bose-Einstein condensate with the atoms moving ballistically either along or against the direction of the applied force. Our results are in agreement with a theoretical analysis of the Floquet spectrum of a model system, thus revealing the existence of diabatic Floquet bands in the atom's band spectra and highlighting their role in the non-equilibrium transport of the atoms

    Theory of semiconductor quantum-wire based single- and two-qubit gates

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    A GaAs/AlGaAs based two-qubit quantum device that allows the controlled generation and straightforward detection of entanglement by measuring a stationary current-voltage characteristic is proposed. We have developed a two-particle Green's function method of open systems and calculate the properties of three-dimensional interacting entangled systems non-perturbatively. We present concrete device designs and detailed, charge self-consistent predictions. One of the qubits is an all-electric Mach-Zehnder interferometer that consists of two electrostatically defined quantum wires with coupling windows, whereas the second qubit is an electrostatically defined double quantum dot located in a second two-dimensional electron gas beneath the quantum wires. We find that the entanglement of the device can be controlled externally by tuning the tunneling coupling between the two quantum dots.Comment: 16 pages, 13 figures, RevTex4 two-column format, to appear in Phys. Rev.

    Understanding the variation of physical elements and their impact on properties and functions: a case study on roll stabilization systems

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    This paper explores the variation in physical elements, functions, and properties of roll stabilization systems in automobiles over successive generations. Two key methodologies, Characteristics-Properties Modelling (CPM) / Property-Driven Development/Design (PDD) and the C&C²-Approach (Contact and Channel Approach), are utilized to analyze the attributes of the system elements and their functional correlations. Through detailed comparison of traditional roll stabilization subsystems and the active roll stabilization system, the research uncovers several correlations between variation types and system properties. The findings show the importance of attribute variation for understanding complex mechatronic systems. The research results may guide future planning of new product generations and foster innovative solutions in the early phases of product development
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