58 research outputs found
Role of malaria exposure on renin-angiotensin aldosterone system polymorphisms and hypertension
Resummed next-to-soft corrections to rapidity distribution of Higgs Boson to
We present the resumed predictions consisting of both soft-virtual(SV) as
well as next-to-SV(NSV) threshold logarithms to all orders in perturbative QCD
for the rapidity distribution of Higgs Boson till
accuracy at LHC. Using our recent formalism\cite{Ajjath:2020lwb}, the
resummation is carried out in the double Mellin space by restricting the NSV
contributions only from diagonal channel. We perform the inverse Mellin
ransformation using the minimal prescription procedure and match it with the
corresponding fixed order results. We do a detailed analysis of the numerical
impact of the resummed result. The K-factor values at different logarithmic
accuracy suggest that the prediction for the rapidity distribution converges
and becomes more reliable at order. We further
observed that the inclusion of resumed NSV contribution improves the
renormalisation scale uncertainty at every order in perturbation theory.
However, the uncertainty due to factorisation scale increases by the addition
of resummed SV+NSV predictions to the fixed order rapidity distribution
Rapidity distribution of pseudo-scalar Higgs boson to
We present the differential predictions for the rapidity distribution of
pseudo-scalar Higgs boson through gluon fusion at the LHC. These results are
obtained taking into account the soft-virtual (SV) as well as the next-to-soft
virtual (NSV) resummation effects to next-to-next-to-leading-logarithmic
() accuracy and matching them to the approximate fixed
order next-to-next-to-leading-order () computation. We perform the
resummation in two dimensional Mellin space using our recent formalism
\cite{Ajjath:2020lwb} by limiting ourselves to the contributions only from
gluon-gluon () initiated channels. The rapidity distribution
of pseudo-scalar Higgs is obtained by applying a ratio method on the NNLO
rapidity distribution of the scalar Higgs boson. We also present the first
analytical results of rapidity distribution of pseudo-scalar Higgs
at SV+NSV accuracy. The phenomenological impacts of
predictions for 13 TeV LHC are studied. We
observe that, for =125(700) GeV, the SV+NSV resummation at level brings about 14.76\% (11.48\%) corrections to the
results at the central scale value of . Further,
we find that the sensitivity to the renormalisation scale gets improved
substantially by the inclusion of NSV resummed predictions at accuracy.Comment: 64 pages, 6 figure
Next-to-soft Virtual Resummation for QCD Observables
We present a framework that resums threshold-enhanced logarithms, originating from soft-virtual and next-to-soft virtual (NSV) contributions in colour-singlet productions, to all orders in perturbation theory. The numerical impacts for these resummed predictions are discussed for the inclusive Drell–Yan di-lepton process up to next-to-next-to-leading logarithmic accuracy, restricting to only diagonal partonic channels
Resummed Higgs boson cross section at next-to SV to
We present the resummed predictions for inclusive cross section for the
production of Higgs boson at next-to-next-to leading logarithmic () accuracy taking into account both soft-virtual ()
and next-to SV () threshold logarithms. We derive the -dependent
coefficients and the -independent constants in Mellin- space for our
study. Using the minimal prescription we perform the inverse Mellin
transformation and match it with the corresponding fixed order results. We
report in detail the numerical impact of -independent part of resummed
result and explore the ambiguity involved in exponentiating them. By studying
the K factors at different logarithmic accuracy, we find that the perturbative
expansion shows better convergence improving the reliability of the prediction
at accuracy. For instance, the cross-section at
accuracy reduces by as compared to the
result for the central scale at 13 TeV LHC.
We also observe that the resummed result improves the
renormalisation scale uncertainty at every order in perturbation theory. The
uncertainty from the renormalisation scale ranges between at whereas it goes down to at
accuracy. However, the factorisation scale
uncertainty is worsened by the inclusion of these NSV logarithms hinting the
importance of resummation beyond terms. We also present our
predictions for resummed result at different collider energies.Comment: 51 pages, 6 Figure
Parthenocarpic potential in Capsicum annuum L. is enhanced by carpelloid structures and controlled by a single recessive gene
<p>Abstract</p> <p>Background</p> <p>Parthenocarpy is a desirable trait in <it>Capsicum annuum </it>production because it improves fruit quality and results in a more regular fruit set. Previously, we identified several <it>C. annuum </it>genotypes that already show a certain level of parthenocarpy, and the seedless fruits obtained from these genotypes often contain carpel-like structures. In the <it>Arabidopsis bel1 </it>mutant ovule integuments are transformed into carpels, and we therefore carefully studied ovule development in <it>C. annuum </it>and correlated aberrant ovule development and carpelloid transformation with parthenocarpic fruit set.</p> <p>Results</p> <p>We identified several additional <it>C. annuum </it>genotypes with a certain level of parthenocarpy, and confirmed a positive correlation between parthenocarpic potential and the development of carpelloid structures. Investigations into the source of these carpel-like structures showed that while the majority of the ovules in <it>C. annuum </it>gynoecia are unitegmic and anatropous, several abnormal ovules were observed, abundant at the top and base of the placenta, with altered integument growth. Abnormal ovule primordia arose from the placenta and most likely transformed into carpelloid structures in analogy to the <it>Arabidopsis bel1 </it>mutant. When pollination was present fruit weight was positively correlated with seed number, but in the absence of seeds, fruit weight proportionally increased with the carpelloid mass and number. <it>Capsicum </it>genotypes with high parthenocarpic potential always showed stronger carpelloid development. The parthenocarpic potential appeared to be controlled by a single recessive gene, but no variation in coding sequence was observed in a candidate gene <it>CaARF8</it>.</p> <p>Conclusions</p> <p>Our results suggest that in the absence of fertilization most <it>C. annuum </it>genotypes, have parthenocarpic potential and carpelloid growth, which can substitute developing seeds in promoting fruit development.</p
Silkworm Thermal Biology: A Review of Heat Shock Response, Heat Shock Proteins and Heat Acclimation in the Domesticated Silkworm, Bombyx mori
Heat shock proteins (HSPs) are known to play ecological and evolutionary roles in this postgenomic era. Recent research suggests that HSPs are implicated in cardiovascular biology and disease development, proliferation and regulation of cancer cells, cell death via apoptosis, and several other key cellular functions. These activities have generated great interest amongst cell and molecular biologists, and these biologists are keen to unravel other hitherto unknown potential functions of this group of proteins. Consequently, the biological significance of HSPs has led to cloning and characterization of genes encoding HSPs in many organisms including the silkworm, Bombyx mori L. (Lepidoptera: Bombycidae). However, most of the past investigations in B. mori were confined to expression of HSPs in tissues and cell lines, whereas information on their specific functional roles in biological, physiological, and molecular processes is scarce. Naturally occurring or domesticated polyvoltines (known to be the tropical race) are more resistant to high temperatures and diseases than bi- or univoltines (temperate races). The mechanism of ecological or evolutionary modification of HSPs during the course of domestication of B. mori - particularly in relation to thermotolerance in geographically distinct races/strains - is still unclear. In addition, the heat shock response, thermal acclimation, and hardening have not been studied extensively in B. mori compared to other organisms. Towards this, recent investigations on differential expression of HSPs at various stages of development, considering the concept of the whole organism, open ample scope to evaluate their biological and commercial importance in B. mori which has not been addressed in any of the representative organisms studied so far. Comparatively, heat shock response among different silkworm races/strains of poly-, bi-, and univoltines varies significantly and thermotolerance increases as the larval development proceeds. Hence, this being the first review in this area, an attempt has been made to collate all available information on the heat shock response, HSPs expression, associated genes, amino acid sequences, and acquired/unacquired thermotolerance. The aim is to present this as a valuable resource for addressing the gap in knowledge and understanding evolutionary significance of HSPs between domesticated (B. mori) and non-domesticated insects. It is believed that the information presented here will also help researchers/breeders to design appropriate strategies for developing novel strains for the tropics
Mapping and characterization of novel parthenocarpy QTLs in tomato
Parthenocarpy is the development of the fruit in absence of pollination and/or fertilization. In tomato, parthenocarpy is considered as an attractive trait to solve the problems of fruit setting under unfavorable conditions. We studied the genetics of parthenocarpy in two different lines, IL5-1 and IVT-line 1, both carrying Solanum habrochaites chromosome segments. Parthenocarpy in IL5-1 is under the control of two QTLs, one on chromosome 4 (pat4.1) and one on chromosome 5 (pat5.1). IVT-line 1 also contains two parthenocarpy QTLs, one on chromosome 4 (pat4.2) and one on chromosome 9 (pat9.1). In addition, we identified one stigma exsertion locus in IL5-1, located on the long arm of chromosome 5 (se5.1). It is likely that pat4.1, from IL5-1 and pat4.2, from IVT-line 1, both located near the centromere of chromosome 4 are allelic. By making use of the microsynteny between tomato and Arabidopsis in this genetic region, we identified ARF8 as a potential candidate gene for these two QTLs. ARF8 is known to act as an inhibitor for further carpel development in Arabidopsis, in absence of pollination/fertilization. Expression of an aberrant form of the ArabidopsisARF8 gene, in tomato, has been found to cause parthenocarpy. This candidate gene approach may lead to the first isolation of a parthenocarpy gene in tomato and will allow further use in several crop species
Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial
Background
Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy
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