984 research outputs found

    Participation of Different Forces and Coeducation in Peking University: From Reports of Newspaper Media, 1918-1920

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    It was an important achievement that Peking University abolished female forbiddance and implemented coeducation in Women’s Liberation Movement during the May 4th New Culture Movement. In this period, newspaper media kept up with the historical trend. As the leader of public opinion, Newspaper media intervened, reported and publicized the abolishment of female forbiddance and the implementation of coeducation in Peking University. It promoted the involvement of different social forces: the Principal of Peking University — Cai Yuanpei, female intellectuals, teachers and students of Peking university. These various forces played different roles in this trend. In their interaction, the abolishment of female forbiddance and the implementation of coeducation in Peking University began with appeals and debates and eventually ended with the realization. Furthermore, it aroused a nationwide impact in the education field. It not only reflects that coeducation in universities is a historical trend of democratization and modernization in higher education, but also indicates that newspaper media plays an indispensable role in Women’s Liberation Movement

    Posouzení finanční pozice vybraného podniku

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    The main purpose of this paper is to conduct a comprehensive analysis of the operational status of selected Alma Media Corporation during the 2013-2017 period using selected financial analysis methods and DuPont analysis. This paper uses a series of professional analytical techniques and methods to improve the profitability of past and present financing activities, investment activities, business activities and distribution activities. Economic management activities are used to analyze and assess business capabilities, solvency and growth capabilities. It helps focus on the past, assessing the company's current situation, predicting the company's future decisions and making accurate decisions.   According to the basic information of Alma Media Corporation, you can understand that in the past Alma  Media Corparation is primarily a media company that prints and publishes newspapers. However, with the development of technology, people no longer rely on the past to obtain information through printed newspapers, people can get the latest news through the network platform. This forced Alma Media to transform. In terms of transformation, Alma Media has made many changes. Alma Markets develops its business by expanding and deepening its services around current entities, including housing, automotive and recruitment.   The ultimate transformation of Alma Media, we can learn from the changes that operating companies need to adapt to the times. Products need to constantly innovate to meet the needs of consumers, rather than stick to a successful business model. It is stubborn that past companies may be expanded by Finland's last economy, and it can try to globalize products, thereby reducing the impact of some external factors. While consumer demand and changes in the national economy may have a negative impact on the company's operations, it also provides opportunities for companies that understand innovation.Hlavním cílem je provést finanční analýza vybraného subjektu v období 2013-2017 za použití vybraných metod finanční analýzy a pyramidálního rozkladu s důrazem na posouzení finančních aktivit, obchodních a prodejních aktivit.154 - Katedra financívelmi dobř

    Porcine rotavirus mainly infects primary porcine enterocytes at the basolateral surface

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    Intestinal epithelium functions as a barrier to protect multicellular organisms from the outside world. It consists of epithelial cells closely connected by intercellular junctions, selective gates which control paracellular difusion of solutes, ions and macromolecules across the epithelium and keep out pathogens. Rotavirus is one of the major enteric viruses causing severe diarrhea in humans and animals. It specifcally infects the enterocytes on villi of small intestines. The polarity of rotavirus replication in their target enterocytes and the role of intestinal epithelial integrity were examined in the present study. Treatment with EGTA, a drug that chelates calcium and disrupts the intercellular junctions, (i) signifcantly enhanced the infection of rotavirus in primary enterocytes, (ii) increased the binding of rotavirus to enterocytes, but (iii) considerably blocked internalization of rotavirus. After internalization, rotavirus was resistant to EGTA treatment. To investigate the polarity of rotavirus infection, the primary enterocytes were cultured in a transwell system and infected with rotavirus at either the apical or the basolateral surface. Rotavirus preferentially infected enterocytes at the basolateral surface. Restriction of infection through apical inoculation was overcome by EGTA treatment. Overall, our fndings demonstrate that integrity of the intestinal epithelium is crucial in the host’s innate defense against rotavirus infection. In addition, the intercellular receptor is located basolaterally and disruption of intercellular junctions facilitates the binding of rotavirus to their receptor at the basolateral surface
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