984 research outputs found
Participation of Different Forces and Coeducation in Peking University: From Reports of Newspaper Media, 1918-1920
It was an important achievement that Peking University abolished female forbiddance and implemented coeducation in Women’s Liberation Movement during the May 4th New Culture Movement. In this period, newspaper media kept up with the historical trend. As the leader of public opinion, Newspaper media intervened, reported and publicized the abolishment of female forbiddance and the implementation of coeducation in Peking University. It promoted the involvement of different social forces: the Principal of Peking University — Cai Yuanpei, female intellectuals, teachers and students of Peking university. These various forces played different roles in this trend. In their interaction, the abolishment of female forbiddance and the implementation of coeducation in Peking University began with appeals and debates and eventually ended with the realization. Furthermore, it aroused a nationwide impact in the education field. It not only reflects that coeducation in universities is a historical trend of democratization and modernization in higher education, but also indicates that newspaper media plays an indispensable role in Women’s Liberation Movement
Estimates of the 2016 global burden of kidney disease attributable to ambient fine particulate matter air pollution
Associations of ambient coarse particulate matter, nitrogen dioxide, and carbon monoxide with the risk of kidney disease: A cohort study
Estimates of all cause mortality and cause specific mortality associated with proton pump inhibitors among US veterans: Cohort study
Long-term kidney outcomes among users of proton pump inhibitors without intervening acute kidney injury
Risk of death among users of Proton Pump Inhibitors: A longitudinal observational cohort study of United States veterans
Posouzení finanční pozice vybraného podniku
The main purpose of this paper is to conduct a comprehensive analysis of the operational status of selected Alma Media Corporation during the 2013-2017 period using selected financial analysis methods and DuPont analysis. This paper uses a series of professional analytical techniques and methods to improve the profitability of past and present financing activities, investment activities, business activities and distribution activities. Economic management activities are used to analyze and assess business capabilities, solvency and growth capabilities. It helps focus on the past, assessing the company's current situation, predicting the company's future decisions and making accurate decisions.
According to the basic information of Alma Media Corporation, you can understand that in the past Alma
Media Corparation is primarily a media company that prints and publishes newspapers. However, with the development of technology, people no longer rely on the past to obtain information through printed newspapers, people can get the latest news through the network platform. This forced Alma Media to transform. In terms of transformation, Alma Media has made many changes. Alma Markets develops its business by expanding and deepening its services around current entities, including housing, automotive and recruitment.
The ultimate transformation of Alma Media, we can learn from the changes that operating companies need to adapt to the times. Products need to constantly innovate to meet the needs of consumers, rather than stick to a successful business model. It is stubborn that past companies may be expanded by Finland's last economy, and it can try to globalize products, thereby reducing the impact of some external factors. While consumer demand and changes in the national economy may have a negative impact on the company's operations, it also provides opportunities for companies that understand innovation.Hlavním cílem je provést finanční analýza vybraného subjektu v období 2013-2017 za použití vybraných metod finanční analýzy a pyramidálního rozkladu s důrazem na posouzení finančních aktivit, obchodních a prodejních aktivit.154 - Katedra financívelmi dobř
Porcine rotavirus mainly infects primary porcine enterocytes at the basolateral surface
Intestinal epithelium functions as a barrier to protect multicellular organisms from the outside world. It consists
of epithelial cells closely connected by intercellular junctions, selective gates which control paracellular difusion
of solutes, ions and macromolecules across the epithelium and keep out pathogens. Rotavirus is one of the major
enteric viruses causing severe diarrhea in humans and animals. It specifcally infects the enterocytes on villi of small
intestines. The polarity of rotavirus replication in their target enterocytes and the role of intestinal epithelial integrity
were examined in the present study. Treatment with EGTA, a drug that chelates calcium and disrupts the intercellular junctions, (i) signifcantly enhanced the infection of rotavirus in primary enterocytes, (ii) increased the binding of
rotavirus to enterocytes, but (iii) considerably blocked internalization of rotavirus. After internalization, rotavirus was
resistant to EGTA treatment. To investigate the polarity of rotavirus infection, the primary enterocytes were cultured
in a transwell system and infected with rotavirus at either the apical or the basolateral surface. Rotavirus preferentially
infected enterocytes at the basolateral surface. Restriction of infection through apical inoculation was overcome by
EGTA treatment. Overall, our fndings demonstrate that integrity of the intestinal epithelium is crucial in the host’s
innate defense against rotavirus infection. In addition, the intercellular receptor is located basolaterally and disruption
of intercellular junctions facilitates the binding of rotavirus to their receptor at the basolateral surface
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