61 research outputs found
Exploring Apprenticeship Learning for Player Modelling in Interactive Narratives
In this paper we present an early Apprenticeship Learning approach to mimic
the behaviour of different players in a short adaption of the interactive
fiction Anchorhead. Our motivation is the need to understand and simulate
player behaviour to create systems to aid the design and personalisation of
Interactive Narratives (INs). INs are partially observable for the players and
their goals are dynamic as a result. We used Receding Horizon IRL (RHIRL) to
learn players' goals in the form of reward functions, and derive policies to
imitate their behaviour. Our preliminary results suggest that RHIRL is able to
learn action sequences to complete a game, and provided insights towards
generating behaviour more similar to specific players.Comment: Extended Abstracts of the 2019 Annual Symposium on Computer-Human
Interaction in Play (CHI Play
A Highly Selective Cc Chemokine Receptor (Ccr)8 Antagonist Encoded by the Poxvirus Molluscum Contagiosum
The MC148 CC chemokine from the human poxvirus molluscum contagiosum (MCV) was probed in parallel with viral macrophage inflammatory protein (vMIP)-II encoded by human herpesvirus 8 (HHV8) in 16 classified human chemokine receptors. In competition binding using radiolabeled endogenous chemokines as well as radiolabeled MC148, MC148 bound with high affinity only to CCR8. In calcium mobilization assays, MC148 had no effect on its own on any of the chemokine receptors, but in a dose-dependent manner blocked the stimulatory effect of the endogenous I-309 chemokine on CCR8 without affecting chemokine-induced signaling of any other receptor. In contrast, vMIP-II acted as an antagonist on 10 of the 16 chemokine receptors, covering all four classes: XCR, CCR, CXCR, and CX3CR. In chemotaxis assays, MC148 specifically blocked the I-309–induced response but, for example, not stromal cell–derived factor 1α, monocyte chemoattractant protein 1, or interleukin 8–induced chemotaxis. We thus concluded that the two viruses choose two different ways to block the chemokine system: HHV8 encodes the broad-spectrum chemokine antagonist vMIP-II, whereas MCV encodes a highly selective CCR8 antagonist, MC148, conceivably to interfere with monocyte invasion and dendritic cell function. Because of its pharmacological selectivity, the MC148 protein could be a useful tool in the delineation of the role played by CCR8 and its endogenous ligand, I-309
Resonant Photonic Quasicrystalline and Aperiodic Structures
We have theoretically studied propagation of exciton-polaritons in
deterministic aperiodic multiple-quantum-well structures, particularly, in the
Fibonacci and Thue-Morse chains. The attention is concentrated on the
structures tuned to the resonant Bragg condition with two-dimensional
quantum-well exciton. The superradiant or photonic-quasicrystal regimes are
realized in these structures depending on the number of the wells. The
developed theory based on the two-wave approximation allows one to describe
analytically the exact transfer-matrix computations for transmittance and
reflectance spectra in the whole frequency range except for a narrow region
near the exciton resonance. In this region the optical spectra and the
exciton-polariton dispersion demonstrate scaling invariance and self-similarity
which can be interpreted in terms of the ``band-edge'' cycle of the trace map,
in the case of Fibonacci structures, and in terms of zero reflection
frequencies, in the case of Thue-Morse structures.Comment: 13 pages, 9 figures, submitted to Phys. Rev.
Критика Юркевичем утилітаризму
This work focuses on studying players behaviour in interactive narratives
with the aim to simulate their choices. Besides sub-optimal player behaviour
due to limited knowledge about the environment, the difference in each player's
style and preferences represents a challenge when trying to make an intelligent
system mimic their actions. Based on observations from players interactions
with an extract from the interactive fiction Anchorhead, we created a player
profile to guide the behaviour of a generic player model based on the BDI
(Belief-Desire-Intention) model of agency. We evaluated our approach using
qualitative and quantitative methods and found that the player profile can
improve the performance of the BDI player model. However, we found that players
self-assessment did not yield accurate data to populate their player profile
under our current approach.Comment: CHI Play 201
Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity
Objective: Given that cellular O-GlcNAcylation levels are thought to be real-time measures of cellular nutrient status and dysregulated O-GlcNAc signaling is associated with insulin resistance, we evaluated the role of O-GlcNAc transferase (OGT), the enzyme that mediates O-GlcNAcylation, in skeletal muscle. Methods: We assessed O-GlcNAcylation levels in skeletal muscle from obese, type 2 diabetic people, and we characterized muscle-specific OGT knockout (mKO) mice in metabolic cages and measured energy expenditure and substrate utilization pattern using indirect calorimetry. Whole body insulin sensitivity was assessed using the hyperinsulinemic euglycemic clamp technique and tissue-specific glucose uptake was subsequently evaluated. Tissues were used for histology, qPCR, Western blot, co-immunoprecipitation, and chromatin immunoprecipitation analyses. Results: We found elevated levels of O-GlcNAc-modified proteins in obese, type 2 diabetic people compared with well-matched obese and lean controls. Muscle-specific OGT knockout mice were lean, and whole body energy expenditure and insulin sensitivity were increased in these mice, consistent with enhanced glucose uptake and elevated glycolytic enzyme activities in skeletal muscle. Moreover, enhanced glucose uptake was also observed in white adipose tissue that was browner than that of WT mice. Interestingly, mKO mice had elevated mRNA levels of Il15 in skeletal muscle and increased circulating IL-15 levels. We found that OGT in muscle mediates transcriptional repression of Il15 by O-GlcNAcylating Enhancer of Zeste Homolog 2 (EZH2). Conclusions: Elevated muscle O-GlcNAc levels paralleled insulin resistance and type 2 diabetes in humans. Moreover, OGT-mediated signaling is necessary for proper skeletal muscle metabolism and whole-body energy homeostasis, and our data highlight O-GlcNAcylation as a potential target for ameliorating metabolic disorders. Keywords: O-GlcNAc signaling, Type 2 diabetes, N-acetyl-d-glucosamine, Tissue cross talk, Epigenetic regulation of Il15 transcription, Insulin sensitivit
Mixed-media game AI
Over the last decades, digital technologies have moved away from the personal computer (PC)
into cloud computing, ubiquitous computing, intelligent robots and smart devices. From wearable
technologies to remote-controlled household items and from sensors for crowd control to personal drones, there is a broad range of sources which can be exploited for artificial intelligence in games. While artificial intelligence (AI) is already a big part of the Internet of Things, raising concerns in terms of ethics and politics, games have been relatively partitioned away to PCs. Relevant work on wearable technologies as game controllers, mixed- or virtual-reality rendering, or technology-enhanced play in playgrounds, social robots for games or board games, has largely not taken advantage of artificial intelligence for controlling or mediating the experience. Using the term mixed-media to refer broadly to any media, digital or otherwise, outside the game data within a PC or a game-specific database, this working group attempted to map out the broad topic of mixed-media in terms of its applications for game AI.peer-reviewe
Nonrepetitive Colouring via Entropy Compression
A vertex colouring of a graph is \emph{nonrepetitive} if there is no path
whose first half receives the same sequence of colours as the second half. A
graph is nonrepetitively -choosable if given lists of at least colours
at each vertex, there is a nonrepetitive colouring such that each vertex is
coloured from its own list. It is known that every graph with maximum degree
is -choosable, for some constant . We prove this result
with (ignoring lower order terms). We then prove that every subdivision
of a graph with sufficiently many division vertices per edge is nonrepetitively
5-choosable. The proofs of both these results are based on the Moser-Tardos
entropy-compression method, and a recent extension by Grytczuk, Kozik and Micek
for the nonrepetitive choosability of paths. Finally, we prove that every graph
with pathwidth is nonrepetitively -colourable.Comment: v4: Minor changes made following helpful comments by the referee
The Impact of Coronavirus (COVID-19) Related Public-Health Measures on Training Behaviours of Individuals Previously Participating in Resistance Training: A Cross-Sectional Survey Study
Introduction Understanding the impact of lockdown upon resistance training (RT), and how people adapted their RT behaviours, has implications for strategies to maintain engagement in similar positive health behaviours. Further, doing so will provide a baseline for investigation of the long-term effects of these public health measures upon behaviours and perceptions, and facilitate future follow-up study. Objectives To determine how the onset of coronavirus (COVID-19), and associated ‘lockdown’, affected RT behaviours, in addition to motivation, perceived effectiveness, enjoyment, and intent to continue, in those who regularly performed RT prior to the pandemic. Methods We conducted an observational, cross-sectional study using online surveys in multiple languages (English, Danish, French, German, Italian, Portuguese, Slovakian, Swedish, and Japanese) distributed across social media platforms and through authors’ professional and personal networks. Adults (n = 5389; median age = 31 years [interquartile range (IQR) = 25, 38]), previously engaged in RT prior to lockdown (median prior RT experience = 7 years [IQR = 4, 12]) participated. Outcomes were self-reported RT behaviours including: continuation of RT during lockdown, location of RT, purchase of specific equipment for RT, method of training, full-body or split routine, types of training, repetition ranges, exercise number, set volumes (per exercise and muscle group), weekly frequency of training, perception of effort, whether training was planned/recorded, time of day, and training goals. Secondary outcomes included motivation, perceived effectiveness, enjoyment, and intent to continue RT. Results A majority of individuals (82.8%) maintained participation in RT during-lockdown. Marginal probabilities from generalised linear models and generalised estimating equations for RT behaviours were largely similar from pre- to during-lockdown. There was reduced probability of training in privately owned gyms (~ 59% to ~ 7%) and increased probability of training at home (~ 18% to ~ 89%); greater probability of training using a full-body routine (~ 38% to ~ 51%); reduced probability of resistance machines (~ 66% to ~ 13%) and free weight use (~ 96% to ~ 81%), and increased probability of bodyweight training (~ 62% to ~ 82%); reduced probability of moderate repetition ranges (~ 62–82% to ~ 55–66%) and greater probability of higher repetition ranges (~ 27% to ~ 49%); and moderate reduction in the perception of effort experienced during-training (r = 0.31). Further, individuals were slightly less likely to plan or record training during lockdown and many changed their training goals. Additionally, perceived effectiveness, enjoyment, and likelihood of continuing current training were all lower during-lockdown. Conclusions Those engaged in RT prior to lockdown these behaviours with only slight adaptations in both location and types of training performed. However, people employed less effort, had lower motivation, and perceived training as less effective and enjoyable, reporting their likelihood of continuing current training was similar or lower than pre-lockdown. These results have implications for strategies to maintain engagement in positive health behaviours such as RT during-restrictive pandemic-related public health measures
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