332 research outputs found

    On the Skin of a Doll

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    When does research end? : the emotional labour of researching abjection

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    In this article, I ask the question: when does research end? I am motivated to engage with this question because I still labour over my doctoral research that I completed a few years ago. Feelings of guilt, shame, and above all, abjection, continue to haunt my subject position of researcher and academic. I seek to trouble the idea that research has clear beginning, middle, and end points, and I reflect on the politics, labour and emotion involved in conducting research, particularly when it involves understandings and experiences of violence. I expose how theoretical and pragmatic decisions, as well as incidents and accidents, leave mnemic traces on our bodies. I demonstrate how personal, theoretical and methodological decisions are complexly intertwined in research, and I argue that it is incumbent upon researchers to think through what they research, why they do it, its effects, and consequences – for researcher, researched, and society

    Unexceptional Violence in Exceptional Times: Disablist and Ableist Violence During the COVID-19 Pandemic

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    It is well established that violence and oppression towards vulnerable and marginalised communities are intensified and compounded during times of social upheaval, and the COVID-19 pandemic has exacerbated disablist and ableist violence against disabled people. During the first year of the pandemic, we have been confronted with instances of violence meted out to disabled subjects. In this article, we provide a theorisation of such violence. Based on an assemblage of our collective readings of Butler, Campbell and Young, as well as our own observations and experiences, we suggest that added anxieties currently confronting people’s fragile corporeal embodiment are licensing abled subjects to violate disabled subjects to put them back in their place. Through an excavation of ‘Norms, Binaries, and Anxieties’, ‘Abjection, Substitutability, and Disavowal’, and ‘Ableism and (Un)grievability’, we trace the social contours of disablist and ableist violence, both within and beyond the context of the COVID-19 pandemic, and provide a way of imagining otherwise to resist this violence.

    Starch mobilization in leaves

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    Starch mobilization is well understood in cereal endosperms, but both the pathway and the regulation of the process are poorly characterized in other types of plant organs. Arabidopsis leaves offer the opportunity for rapid progress in this area, because of the genomic resources available in this species and the ease with which starch synthesis and degradation can be monitored and manipulated. Progress in understanding three aspects of starch degradation is described: the role of disproportionating enzyme, the importance of phosphorolytic degradation, and new evidence about the involvement of a starch‐phosphorylating enzyme in the degradative process. Major areas requiring further research are outline

    A dual process model of emotion

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    The thesis brings together philosophical, psychological and neuroscientific theories of affect in developing a dual process account of emotion. Philosophers and psychologists who take a cognitivist view claim that emotions in humans and other mammalian species require intentionality, arising as the product of evaluations which bear upon our survival or wellbeing, whereas neuroscientists conclude from their research that emotion has its foundations in subcortical affect mechanisms by which behaviours may arise as spontaneous responses to valuable stimuli. Parts I and II of the thesis examine these two accounts, which are construed as cognitive-evaluative and primitive emotional processes respectively. It is further proposed that both these manifestations of emotion are to be found in mammalian species. Given that cognitive-evaluative and primitive emotional states can be demonstrated to coexist and function separately in mammalian species, how do we explain cases in which the two processes seem to be non-accidentally associated? To exemplify: how does it come about that an appraisal that I have been unfairly treated is accompanied by aggressive feelings and impulses towards the object of my anger? Cognitivists accept that the somatic changes accompanying emotions are associated with appraisals but argue that such changes play no role in emotion as an evaluative process other than that of marking the appraisal as significant for our wellbeing. In contrast, a dual process model of emotion is proposed for the interaction of primitive emotions and emotional appraisals whereby the appraisal process arouses a primitive emotion through the detection of patterns within complex external contexts which have a significance for an individual’s wellbeing. The neurophysiological changes associated with the primitive emotion when so aroused, will in turn, invest the appraisal with feelings, sensations characteristic of those neurophysiologies. These feelings influence evaluation in ways which are fundamental to the successful performance of everyday mental functions

    Moral judgement development during medical student clinical training

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    Background: Whereas experience and cognitive maturity drives moral judgement development in most young adults, medical students show slowing, regression, or segmentation in moral development during their clinical years of training. The aim of this study was to explore the moral development of medical students during clinical training. Methods: A cross-sectional sample of medical students from three clinical years of training were interviewed in groups or individually at an Australian medical school in 2018. Thematic analysis identified three themes which were then mapped against the stages and dimensions of Self-authorship Theory. Results: Thirty five medical students from years 3–5 participated in 11 interviews and 6 focus groups. Students shared the impacts of their clinical experiences as they identified with their seniors and increasingly understood the clinical context. Their accounts revealed themes of early confusion followed by defensiveness characterised by desensitization and justification. As students approached graduation, some were planning how they would make moral choices in their future practice. These themes were mapped to the stages of self-authorship: External Formulas, Crossroads and Self-authorship. Conclusions: Medical students recognise, reconcile and understand moral decisions within clinical settings to successfully reach or approach self-authorship. Curriculum and support during clinical training should match and support this progress

    Brain transcriptome sequencing and assembly of three songbird model systems for the study of social behavior

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    Funding for this work was provided by the US National Institutes of Health, National Institute for General Medical Sciences 1RC1GM091556 (to David F. Clayton), the US National Science Foundation, Division of Integrative Organismal Systems 1010429 (to John C. Wingfield), the University Research Council at Indiana State University, NIH 1R01GM084229 (to EM Tuttle and RA Gonser) and East Carolina University. The following grant information was disclosed by the authors: NIH: 1RC1GM091556. NSF: IOS-1010429. University Research Council at Indiana State University NIH: 1R01GM084229. East Carolina University

    MINT and IntAct contribute to the Second BioCreative challenge: serving the text-mining community with high quality molecular interaction data

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    In the absence of consolidated pipelines to archive biological data electronically, information dispersed in the literature must be captured by manual annotation. Unfortunately, manual annotation is time consuming and the coverage of published interaction data is therefore far from complete. The use of text-mining tools to identify relevant publications and to assist in the initial information extraction could help to improve the efficiency of the curation process and, as a consequence, the database coverage of data available in the literature. The 2006 BioCreative competition was aimed at evaluating text-mining procedures in comparison with manual annotation of protein-protein interactions
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