166 research outputs found
Visualizing Spacetime Curvature via Frame-Drag Vortexes and Tidal Tendexes II. Stationary Black Holes
When one splits spacetime into space plus time, the Weyl curvature tensor
(which equals the Riemann tensor in vacuum) splits into two spatial, symmetric,
traceless tensors: the tidal field , which produces tidal forces, and the
frame-drag field , which produces differential frame dragging. In recent
papers, we and colleagues have introduced ways to visualize these two fields:
tidal tendex lines (integral curves of the three eigenvector fields of ) and
their tendicities (eigenvalues of these eigenvector fields); and the
corresponding entities for the frame-drag field: frame-drag vortex lines and
their vorticities. These entities fully characterize the vacuum Riemann tensor.
In this paper, we compute and depict the tendex and vortex lines, and their
tendicities and vorticities, outside the horizons of stationary (Schwarzschild
and Kerr) black holes; and we introduce and depict the black holes' horizon
tendicity and vorticity (the normal-normal components of and on the
horizon). For Schwarzschild and Kerr black holes, the horizon tendicity is
proportional to the horizon's intrinsic scalar curvature, and the horizon
vorticity is proportional to an extrinsic scalar curvature. We show that, for
horizon-penetrating time slices, all these entities (, , the tendex lines
and vortex lines, the lines' tendicities and vorticities, and the horizon
tendicities and vorticities) are affected only weakly by changes of slicing and
changes of spatial coordinates, within those slicing and coordinate choices
that are commonly used for black holes. [Abstract is abbreviated.]Comment: 19 pages, 7 figures, v2: Changed to reflect published version
(changes made to color scales in Figs 5, 6, and 7 for consistent
conventions). v3: Fixed Ref
Visualizing Spacetime Curvature via Frame-Drag Vortexes and Tidal Tendexes III. Quasinormal Pulsations of Schwarzschild and Kerr Black Holes
In recent papers, we and colleagues have introduced a way to visualize the
full vacuum Riemann curvature tensor using frame-drag vortex lines and their
vorticities, and tidal tendex lines and their tendicities. We have also
introduced the concepts of horizon vortexes and tendexes and 3-D vortexes and
tendexes (regions where vorticities or tendicities are large). Using these
concepts, we discover a number of previously unknown features of quasinormal
modes of Schwarzschild and Kerr black holes. These modes can be classified by
mode indexes (n,l,m), and parity, which can be electric [(-1)^l] or magnetic
[(-1)^(l+1)]. Among our discoveries are these: (i) There is a near duality
between modes of the same (n,l,m): a duality in which the tendex and vortex
structures of electric-parity modes are interchanged with the vortex and tendex
structures (respectively) of magnetic-parity modes. (ii) This near duality is
perfect for the modes' complex eigenfrequencies (which are well known to be
identical) and perfect on the horizon; it is slightly broken in the equatorial
plane of a non-spinning hole, and the breaking becomes greater out of the
equatorial plane, and greater as the hole is spun up; but even out of the plane
for fast-spinning holes, the duality is surprisingly good. (iii)
Electric-parity modes can be regarded as generated by 3-D tendexes that stick
radially out of the horizon. As these "longitudinal," near-zone tendexes rotate
or oscillate, they generate longitudinal-transverse near-zone vortexes and
tendexes, and outgoing and ingoing gravitational waves. The ingoing waves act
back on the longitudinal tendexes, driving them to slide off the horizon, which
results in decay of the mode's strength. (iv) By duality, magnetic-parity modes
are driven in this same manner by longitudinal, near-zone vortexes that stick
out of the horizon. [Abstract abridged.]Comment: 53 pages with an overview of major results in the first 11 pages, 26
figures. v2: Very minor changes to reflect published version. v3: Fixed Ref
Visualizing Spacetime Curvature via Frame-Drag Vortexes and Tidal Tendexes I. General Theory and Weak-Gravity Applications
When one splits spacetime into space plus time, the Weyl curvature tensor
(vacuum Riemann tensor) gets split into two spatial, symmetric, and trace-free
(STF) tensors: (i) the Weyl tensor's so-called "electric" part or tidal field,
and (ii) the Weyl tensor's so-called "magnetic" part or frame-drag field. Being
STF, the tidal field and frame-drag field each have three orthogonal
eigenvector fields which can be depicted by their integral curves. We call the
integral curves of the tidal field's eigenvectors tendex lines, we call each
tendex line's eigenvalue its tendicity, and we give the name tendex to a
collection of tendex lines with large tendicity. The analogous quantities for
the frame-drag field are vortex lines, their vorticities, and vortexes. We
build up physical intuition into these concepts by applying them to a variety
of weak-gravity phenomena: a spinning, gravitating point particle, two such
particles side by side, a plane gravitational wave, a point particle with a
dynamical current-quadrupole moment or dynamical mass-quadrupole moment, and a
slow-motion binary system made of nonspinning point particles. [Abstract is
abbreviated; full abstract also mentions additional results.]Comment: 25 pages, 20 figures, matches the published versio
Frame-Dragging Vortexes and Tidal Tendexes Attached to Colliding Black Holes: Visualizing the Curvature of Spacetime
When one splits spacetime into space plus time, the spacetime curvature (Weyl
tensor) gets split into an "electric" part E_{jk} that describes tidal gravity
and a "magnetic" part B_{jk} that describes differential dragging of inertial
frames. We introduce tools for visualizing B_{jk} (frame-drag vortex lines,
their vorticity, and vortexes) and E_{jk} (tidal tendex lines, their tendicity,
and tendexes), and also visualizations of a black-hole horizon's (scalar)
vorticity and tendicity. We use these tools to elucidate the nonlinear dynamics
of curved spacetime in merging black-hole binaries.Comment: 4 pages, 5 figure
Frame-Dragging Vortexes and Tidal Tendexes Attached to Colliding Black Holes: Visualizing the Curvature of Spacetime
When one splits spacetime into space plus time, the spacetime curvature (Weyl
tensor) gets split into an "electric" part E_{jk} that describes tidal gravity
and a "magnetic" part B_{jk} that describes differential dragging of inertial
frames. We introduce tools for visualizing B_{jk} (frame-drag vortex lines,
their vorticity, and vortexes) and E_{jk} (tidal tendex lines, their tendicity,
and tendexes), and also visualizations of a black-hole horizon's (scalar)
vorticity and tendicity. We use these tools to elucidate the nonlinear dynamics
of curved spacetime in merging black-hole binaries.Comment: 4 pages, 5 figure
Detection of prions in the faeces of sheep naturally infected with classical scrapie
Classical scrapie is a naturally transmitted prion disease of sheep and goats. Contaminated environments may contribute to the spread of disease and evidence from animal models has implicated urine, blood, saliva, placenta and faeces as possible sources of the infection. Here we sought to determine whether sheep naturally infected with classical scrapie shed prions in their faeces. We used serial protein misfolding cyclic amplification (sPMCA) along with two extraction methods to examine faeces from sheep during both the clinical and preclinical phases of the disease and showed amplification of PrPSc in 7 of 15 and 14 of 14 sheep respectively. However PrPSc was not amplified from the faeces of 25 sheep not exposed to scrapie. These data represent the first demonstration of prion shedding in faeces from a naturally infected host and thus a likely source of prion contamination in the environment
A Six-Gene Signature Predicts Survival of Patients with Localized Pancreatic Ductal Adenocarcinoma
Jen Jen Yeh and colleagues developed and validated a six-gene signature in patients with pancreatic ductal adenocarcinoma that may be used to better stage the disease in these patients and assist in treatment decisions
The nationwide impact of COVID-19 on life support courses. A retrospective evaluation by Resuscitation Council UK
Aim:
To determine the impact of the COVID-19 pandemic on Resuscitation Council UK Advanced Life Support (ALS) and Immediate Life Support (ILS) course numbers and outcomes.
Methods:
We conducted a before-after study using course data from the Resuscitation Council UK Learning Management System between January 2018 and December 2021, using 23 March 2020 as the cut-off between pre- and post-pandemic periods. Demographics and outcomes were analysed using chi-squared tests and regression models.
Results:
There were 90,265 ALS participants (51,464 pre-; 38,801 post-) and 368,140 ILS participants (225,628 pre-; 142,512 post-). There was a sharp decline in participants on ALS/ILS courses due to COVID-19. ALS participant numbers rebounded to exceed pre-pandemic levels, whereas ILS numbers recovered to a lesser degree with increased uptake of e-learning versions. Mean ALS course participants reduced from 20.0 to 14.8 post-pandemic (P < 0.001).
Post-pandemic there were small but statistically significant decreases in ALS Cardiac Arrest Simulation Test pass rates (from 82.1 % to 80.1 % (OR = 0.90, 95 % CI = 0.86–0.94, P < 0.001)), ALS MCQ score (from 86.6 % to 86.0 % (mean difference = -0.35, 95 % CI −0.44 to −0.26, P < 0.001)), and overall ALS course results (from 95.2 %to 94.7 %, OR = 0.92, CI = 0.85–0.99, P = 0.023). ILS course outcomes were similar post-pandemic (from 99.4 % to 99.4 %, P = 0.037).
Conclusion:
COVID-19 caused a sharp decline in the number of participants on ALS/ILS courses and an accelerated uptake of e-learning versions, with the average ALS course size reducing significantly. The small reduction in performance on ALS courses requires further research to clarify the contributing factors
Testing gravitational-wave searches with numerical relativity waveforms: Results from the first Numerical INJection Analysis (NINJA) project
The Numerical INJection Analysis (NINJA) project is a collaborative effort
between members of the numerical relativity and gravitational-wave data
analysis communities. The purpose of NINJA is to study the sensitivity of
existing gravitational-wave search algorithms using numerically generated
waveforms and to foster closer collaboration between the numerical relativity
and data analysis communities. We describe the results of the first NINJA
analysis which focused on gravitational waveforms from binary black hole
coalescence. Ten numerical relativity groups contributed numerical data which
were used to generate a set of gravitational-wave signals. These signals were
injected into a simulated data set, designed to mimic the response of the
Initial LIGO and Virgo gravitational-wave detectors. Nine groups analysed this
data using search and parameter-estimation pipelines. Matched filter
algorithms, un-modelled-burst searches and Bayesian parameter-estimation and
model-selection algorithms were applied to the data. We report the efficiency
of these search methods in detecting the numerical waveforms and measuring
their parameters. We describe preliminary comparisons between the different
search methods and suggest improvements for future NINJA analyses.Comment: 56 pages, 25 figures; various clarifications; accepted to CQ
Future perspectives in melanoma research. Meeting report from the "Melanoma Research: a bridge Naples-USA. Naples, December 6th-7 th2010"
Progress in understanding the molecular basis of melanoma has made possible the identification of molecular targets with important implications in clinical practice. In fact, new therapeutic approaches are emerging from basic science and it will be important to implement their rapid translation into clinical practice by active clinical investigation
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