The replacement histone H2A.Z in a hyperacetylated form is a feature of active genes in the chicken

The replacement histone H2A.Z is variously reported as being linked to gene expression and preventing the spread of heterochromatin in yeast, or concentrated at heterochromatin in mammals. To resolve this apparent dichotomy, affinity-purified antibodies against the N-terminal region of H2A.Z, in both a triacetylatedandnon- acetylatedstate, areusedin native chromatin immmuno-precipitation experiments with mononucleosomes from three chicken cell types. The hyperacetylated species concentrates at the 50 end of active genes, both tissue specific and housekeeping but is absent from inactive genes, while the unacetylated form is absent from both active and inactive genes. A concentration of H2A.Z is also found at insulators under circumstances implying a link to barrier activity but not to enhancer blocking. Although acetylated H2A.Z is widespread throughout the interphase genome, at mitosis its acetylation is erased, the unmodified form remaining. Thus, although H2A.Z may operate as an epigenetic marker for active genes, its N-terminal acetylation does not

The replacement histone H2A.Z in a hyperacetylated form is a feature of active genes in the chicken

The replacement histone H2A.Z is variously reported as being linked to gene expression and preventing the spread of heterochromatin in yeast, or concentrated at heterochromatin in mammals. To resolve this apparent dichotomy, affinity-purified antibodies against the N-terminal region of H2A.Z, in both a triacetylatedandnon- acetylatedstate, areusedin native chromatin immmuno-precipitation experiments with mononucleosomes from three chicken cell types. The hyperacetylated species concentrates at the 50 end of active genes, both tissue specific and housekeeping but is absent from inactive genes, while the unacetylated form is absent from both active and inactive genes. A concentration of H2A.Z is also found at insulators under circumstances implying a link to barrier activity but not to enhancer blocking. Although acetylated H2A.Z is widespread throughout the interphase genome, at mitosis its acetylation is erased, the unmodified form remaining. Thus, although H2A.Z may operate as an epigenetic marker for active genes, its N-terminal acetylation does not

The Emission of Electromagnetic Radiation from Charges Accelerated by Gravitational Waves and its Astrophysical Implications

We provide calculations and theoretical arguments supporting the emission of electromagnetic radiation from charged particles accelerated by gravitational waves (GWs). These waves have significant indirect evidence to support their existence, yet they interact weakly with ordinary matter. We show that the induced oscillations of charged particles interacting with a GW, which lead to the emission of electromagnetic radiation, will also result in wave attenuation. These ideas are supported by a small body of literature, as well as additional arguments for particle acceleration based on GW memory effects. We derive order of magnitude power calculations for various initial charge distributions accelerated by GWs. The resulting power emission is extremely small for all but very strong GWs interacting with large quantities of charge. If the results here are confirmed and supplemented, significant consequences such as attenuation of early universe GWs could result. Additionally, this effect could extend GW detection techniques into the electromagnetic regime. These explorations are worthy of study to determine the presence of such radiation, as it is extremely important to refine our theoretical framework in an era of active GW astrophysics.Comment: Appears in Gravitational Wave Astrophysics, Editor C.F. Sopuerta, Astrophysics and Space Science Proceedings, Volume 40. ISBN 978-3-319-10487-4. Springer International Publishing Switzerland, 2015, p. 30

RIVER-RAD: A computer code for simulating the transport of radionuclides in rivers

A screening-level model, RIVER-RAD, has been developed to assess the potential fate of radionuclides released to rivers. The model is simplified in nature and is intended to provide guidance in determining the potential importance of the surface water pathway, relevant transport mechanisms, and key radionuclides in estimating radiological dose to man. The purpose of this report is to provide a description of the model and a user's manual for the FORTRAN computer code

Vortex Pinball Under Crossed AC Drives in Superconductors with Periodic Pinning Arrays

Vortices driven with both a transverse and a longitudinal AC drive which are out of phase are shown to exhibit a novel commensuration-incommensuration effect when interacting with periodic substrates. For different AC driving parameters, the motion of the vortices forms commensurate orbits with the periodicity of the pinning array. When the commensurate orbits are present, there is a finite DC critical depinning threshold, while for the incommensurate phases the vortices are delocalized and the DC depinning threshold is absent.Comment: 4 pages, 4 postscript figure

Plasma Wave Properties of the Schwarzschild Magnetosphere in a Veselago Medium

We re-formulate the 3+1 GRMHD equations for the Schwarzschild black hole in a Veselago medium. Linear perturbation in rotating (non-magnetized and magnetized) plasma is introduced and their Fourier analysis is considered. We discuss wave properties with the help of wave vector, refractive index and change in refractive index in the form of graphs. It is concluded that some waves move away from the event horizon in this unusual medium. We conclude that for the rotating non-magnetized plasma, our results confirm the presence of Veselago medium while the rotating magnetized plasma does not provide any evidence for this medium.Comment: 20 pages, 15 figures, accepted for publication in Astrophys. Space Sc

Uncertainty in Signals of Large-Scale Climate Variations in Radiosonde and Satellite Upper-Air Temperature Datasets

There is no single reference dataset of long-term global upper-air temperature observations, although several groups have developed datasets from radiosonde and satellite observations for climate-monitoring purposes. The existence of multiple data products allows for exploration of the uncertainty in signals of climate variations and change. This paper examines eight upper-air temperature datasets and quantifies the magnitude and uncertainty of various climate signals, including stratospheric quasi-biennial oscillation (QBO) and tropospheric ENSO signals, stratospheric warming following three major volcanic eruptions, the abrupt tropospheric warming of 1976–77, and multidecadal temperature trends. Uncertainty estimates are based both on the spread of signal estimates from the different observational datasets and on the inherent statistical uncertainties of the signal in any individual dataset. The large spread among trend estimates suggests that using multiple datasets to characterize large-scale upperair temperature trends gives a more complete characterization of their uncertainty than reliance on a single dataset. For other climate signals, there is value in using more than one dataset, because signal strengths vary. However, the purely statistical uncertainty of the signal in individual datasets is large enough to effectively encompass the spread among datasets. This result supports the notion of an 11th climate-monitoring principle, augmenting the 10 principles that have now been generally accepted (although not generally implemented) by the climate community. This 11th principle calls for monitoring key climate variables with multiple, independent observing systems for measuring the variable, and multiple, independent groups analyzing the data

Species of Bursaphelenchus Fuchs, 1937 (Nematoda: Parasitaphelenchidae) and other nematode genera associated with insects from Pinus pinaster in Portugal

Insects associated with maritime pine, Pinus pinaster, in Portugal were collected and screened for the presence of Bursaphelenchus species. Nematodes were identified using Internal Transcribed Spacers-Restriction Fragment Length Polymorphism (ITS-RFLP) analysis of dauer juveniles and morphological identification of adults that developed from dauer juveniles on fungal cultures or on cultures in pine wood segments at 26 C. Several associations are described: Bursaphelenchus teratospicularis and Bursaphelenchus sexdentati are associated with Orthotomicus erosus; Bursaphelenchus tusciae, B. sexdentati and/or Bursaphelenchus pinophilus with Hylurgus ligniperda and Bursaphelenchus hellenicus with Tomicus piniperda, Ips sexdentatus and H. ligniperda. An unidentified Bursaphelenchus species is vectored by Hylobius sp. The previously reported association of Bursaphelenchus xylophilus with Monochamus galloprovincialis was confirmed. The association of Bursaphelenchus leoni with Pityogenes sp. is not definitively established and needs further studies for clarification. Other nematode genera besides Bursaphelenchus were found to be associated with the insects sampled, including two different species of Ektaphelenchus, Parasitorhabditis sp., Parasitaphelenchus sp., Contortylenchus sp. and other unidentified nematodes. The Ektaphelenchus species found in O. erosus is morphologically similar to B. teratospicularis found in the same insect; adults of both the species are found in cocoon-like structures under the elytra of the insects. Introduction Approximately one third of the nematodes belonging to the order Aphelenchida Siddiqi, 1980 are associated with insects (Poinar, 1983). These nematodes establish a variety of associations with the insects, which may be described as commensalism, e.g. phoresy (to the benefit of the nematode but not affecting the insect), mutualism (both the organisms benefit) or parasitism (nematodes benefit at the expense of the insect) (Giblin-Davis, 2004). Most Bursaphelenchus Fuchs, 1937 species are mycetophagous, feeding on fungi in the galleries of bark beetles and thu

Creation of the CMB spectrum: precise analytic solutions for the blackbody photosphere

The blackbody spectrum of CMB was created in the blackbody photosphere at redshifts z>2x10^6. At these early times, the Universe was dense and hot enough that complete thermal equilibrium between baryonic matter (electrons and ions) and photons could be established. Any perturbation away from the blackbody spectrum was suppressed exponentially. New physics, for example annihilation and decay of dark matter, can add energy and photons to CMB at redshifts z>10^5 and result in a Bose-Einstein spectrum with a non-zero chemical potential ($\mu$). Precise evolution of the CMB spectrum around the critical redshift of z~2x10^6 is required in order to calculate the $\mu$-type spectral distortion and constrain the underlying new physics. Although numerical calculation of important processes involved (double Compton process, comptonization and bremsstrahlung) is not difficult, analytic solutions are much faster and easier to calculate and provide valuable physical insights. We provide precise (better than 1%) analytic solutions for the decay of $\mu$, created at an earlier epoch, including all three processes, double Compton, Compton scattering on thermal electrons and bremsstrahlung in the limit of small distortions. This is a significant improvement over the existing solutions with accuracy ~10% or worse. We also give a census of important sources of energy injection into CMB in standard cosmology. In particular, calculations of distortions from electron-positron annihilation and primordial nucleosynthesis illustrate in a dramatic way the strength of the equilibrium restoring processes in the early Universe. Finally, we point out the triple degeneracy in standard cosmology, i.e., the $\mu$ and $y$ distortions from adiabatic cooling of baryons and electrons, Silk damping and annihilation of thermally produced WIMP dark matter are of similar order of magnitude (~ 10^{-8}-10^{-10})