3,553 research outputs found

    Borderland Blacks: Two Cities in the Niagara Region during the Final Decades of Slavery

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    dann J. Broyld offers a “pivotal new understanding of the geopolitics and the confluences of the Underground Railroad and Black mobility, identity, and abolitionism on both sides of the American-Canadian border in Western New York

    Evaluation of the Induction of Immune Memory following Infant Immunisation with Serogroup C Neisseria meningitidis Conjugate Vaccines - Exploratory Analyses within a Randomised Controlled Trial

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    Aim: We measured meningococcal serogroup C (MenC)-specific memory B-cell responses in infants by Enzyme-Linked Immunospot (ELISpot) following different MenC conjugate vaccine schedules to investigate the impact of priming on immune memory. Methods: Infants aged 2 months were randomised to receive 1 or 2 doses of MenC-CRM197 at 3 or 3 and 4 months, 1 dose of MenC-TT at 3 months, or no primary MenC doses. All children received a Haemophilus influenzae type b (Hib)-MenC booster at 12 months. Blood was drawn at 5, 12, 12 months +6 days and 13 months of age. Results: Results were available for 110, 103, 76 and 44 children from each group respectively. Following primary immunisations, and prior to the 12-month booster, there were no significant differences between 1- or 2-dose primed children in the number of MenC memory B-cells detected. One month following the booster, children primed with 1 dose MenC-TT had more memory B-cells than children primed with either 1-dose (p = 0.001) or 2-dose (p<0.0001) MenC-CRM197. There were no differences in MenC memory B-cells detected in children who received 1 or 2 doses of MenC-CRM197 in infancy and un-primed children. Conclusions: MenC-specific memory B-cell production may be more dependent on the type of primary vaccine used than the number of doses administered. Although the mechanistic differences between MenC-CRM197 and MenC-TT priming are unclear, it is possible that structural differences, including the carrier proteins, may underlie differential interactions with B- and T-cell populations, and thus different effects on various memory B-cell subsets. A MenC-TT/Hib-MenC-TT combination for priming/boosting may offer an advantage in inducing more persistent antibody.peer-reviewe

    Dramaturgies of Democracy: Performance, Cultural Policy, and Citizenship in Chile, 1979–Present

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    This dissertation examines the relationship between performance, cultural policy, and citi­zenship in Chile (1979-present). Through emblematic case studies of key performance interventions (including the work of the Colectivo Acciones de Arte [CADA], Andrés Pérez, Manuela Infante, and Guillermo Calderón), intertwined with analyses of cultural policy and political discourse, I ask how Chilean performance dramaturgically enacts forms of democratic citizenship—first during Pinochet’s dictatorship as a hoped-for future and later, fol­lowing the democratic transition, as a present, if incomplete, reality. Re­sponding to the vexed transitions to democracy, scholarship on Latin American theatre and performance has emphasized its resistance to the state. I complicate this formulation by examining how these per­formances have been shaped by the political and institutional structures contingent to their produc­tion and by considering how critical po­litical performance is a category produced, in part, by the state. I therefore develop a model that allows for a more nuanced understanding of the performing arts to poli­tics—one that accounts for an interdepend­ent, sometimes paradoxical, and often mutu­ally constitutive dynamic

    A Geoarcheological Survey of the Proposed Plainview Hike and Bike Trail, Hale County, Texas

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    In March of 2005, the Texas Department of Transportation issued work authorization #575-01-SA005 to the Center for Archaeological Research (CAR) at the University of Texas at San Antonio to conduct a survey of areas affected by proposed improvements to the Plainview hike and bike trail in southern Plainview, Hale County, Texas. The survey was conduced under Texas Antiquities Permit #3707 between March 31 and April 7, 2005. Steve Tomka and Raymond Mauldin served as Principal Investigators. Trail construction included 2.0 miles of additional construction and 1.3 miles of improvements to existing trails. The Right-of-Way is 50 feet and extends from one to three feet below ground surface. Archeological services included a pedestrian survey, excavation of fifty-five auger tests placed no more than 100 m apart, and twenty-one Gradall trenches. Two of these trenches exposed the stratigraphy of Running Water Draw near the Plainview Site, 41HA1. Bulk samples were collected for OSL dating, diatoms analysis, and lithologic analysis for further examination of the age and stratigraphic context of the Plainview Site, which is a State Archeological Landmark, a National Landmark, and a National Register of Historic Places property. Site 41HA12 was re-examined with 10 mechanical auger tests and 1 trench, which found only recent alluvial and cultural deposition. No additional archeological sites were recorded. This report includes descriptions of the fieldwork, results of the special analyses performed on bulk sediment samples collected, and a discussion of the geomorphology of Running Water Draw with specific focus on the results from trenches excavated near the Plainview Site. The single artifact and all documents and photographs generated from this project are curated at the Center for Archaeological Research at The University of Texas at San Antonio

    Psychometric Properties of the Family Caregiver Delirium Knowledge Questionnaire

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    A valid, reliable measure of family caregivers’ knowledge about delirium was not located in the literature; such an instrument is essential to assess learning needs and outcomes of education provided. The purpose of the current study was to (a) develop a family Caregiver Delirium Knowledge Questionnaire (CDKQ) based on the Symptom Interpretation Model; and (b) establish validity and reliability of the measure. The 19-item CDKQ was developed and administered to 164 family caregivers for community-dwelling older adults. Descriptive statistics were examined for all variables. Psychometric testing included confirmatory factor analysis, item-to-total correlations, and internal consistency reliability. A three-factor model provided the best fit for the data. The findings support initial validity and reliability of the CDKQ with family caregivers. Although the CDKQ was developed for use with family caregivers, it has potential for use with other caregivers, such as home health aides

    Comparing cover crop research in farmer-led and researcher-led experiments in the Western Corn Belt

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    Cover crops can mitigate soil degradation and nutrient loss and can be used to achieve continuous living cover in cropping systems, although their adoption in the Western Corn Belt of the United States remains low. It is increasingly recognized that cover crop integration into corn (Zea mays L.)-based crop rotations is complex, requiring site and operation specific management. In this review, we compared on-farm, farmer-led field scale trials to researcher-led trials carried out in small plots on University of Nebraska-Lincoln experiment stations. Although there is a range of cover crop research conducted in the state, there is no synthesis of the scope and key results of such eorts. Common cover crop challenges and goals in the state are similar to those reported nationwide; challenges include adequate planting timing, associated costs, and weather, while a top goal of cover crop use is to improve soil health. Farmer-led trials most frequently compared a cover crop to a no-cover crop control, likely reflecting a desire to test a basic design determining site-specific performance. Both researcher-led and farmer-led trials included designs testing cash crop planting timing, while some portion of farmer-led trials tested cover crop seeding rates, which are directly related to reported cover crop challenges. Farmer-led trials were carried out on a greater variety of soils, including sandy soils, whereas sandy soils were absent from researcher-led trials. More than half of farmer- led experiments were conducted on fields with slopes of 6–17% while most researcher-led experiments were conducted on fields with slopes of \u3c1%. Mean cover crop biomass production was 600 kg/ha in farmer-led and 2,000 kg/ha in researcher-led trials. Crop yields were not significantly aected by cover crops in either farmer-led or researcher-led trials. Such comparisons demonstrate that in some instances, cover crop research is addressing challenges, and in some instances, it could be expanded. This synthesis expands our knowledge base in a way that can promote co-learning between dierent scales of experiments, and ultimately, reduce risks associated with cover crop management and further promote continuous living cover of agricultural landscapes
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