3,553 research outputs found
Borderland Blacks: Two Cities in the Niagara Region during the Final Decades of Slavery
dann J. Broyld offers a “pivotal new understanding of the geopolitics and the confluences of the Underground Railroad and Black mobility, identity, and abolitionism on both sides of the American-Canadian border in Western New York
Evaluation of the Induction of Immune Memory following Infant Immunisation with Serogroup C Neisseria meningitidis Conjugate Vaccines - Exploratory Analyses within a Randomised Controlled Trial
Aim: We measured meningococcal serogroup C (MenC)-specific memory B-cell responses in infants by Enzyme-Linked Immunospot (ELISpot) following different MenC conjugate vaccine schedules to investigate the impact of priming on immune memory. Methods: Infants aged 2 months were randomised to receive 1 or 2 doses of MenC-CRM197 at 3 or 3 and 4 months, 1 dose of MenC-TT at 3 months, or no primary MenC doses. All children received a Haemophilus influenzae type b (Hib)-MenC booster at 12 months. Blood was drawn at 5, 12, 12 months +6 days and 13 months of age. Results: Results were available for 110, 103, 76 and 44 children from each group respectively. Following primary immunisations, and prior to the 12-month booster, there were no significant differences between 1- or 2-dose primed children in the number of MenC memory B-cells detected. One month following the booster, children primed with 1 dose MenC-TT had more memory B-cells than children primed with either 1-dose (p = 0.001) or 2-dose (p<0.0001) MenC-CRM197. There were no differences in MenC memory B-cells detected in children who received 1 or 2 doses of MenC-CRM197 in infancy and un-primed children. Conclusions: MenC-specific memory B-cell production may be more dependent on the type of primary vaccine used than the number of doses administered. Although the mechanistic differences between MenC-CRM197 and MenC-TT priming are unclear, it is possible that structural differences, including the carrier proteins, may underlie differential interactions with B- and T-cell populations, and thus different effects on various memory B-cell subsets. A MenC-TT/Hib-MenC-TT combination for priming/boosting may offer an advantage in inducing more persistent antibody.peer-reviewe
Dramaturgies of Democracy: Performance, Cultural Policy, and Citizenship in Chile, 1979–Present
This dissertation examines the relationship between performance, cultural policy, and citiÂzenship in Chile (1979-present). Through emblematic case studies of key performance interventions (including the work of the Colectivo Acciones de Arte [CADA], Andrés Pérez, Manuela Infante, and Guillermo Calderón), intertwined with analyses of cultural policy and political discourse, I ask how Chilean performance dramaturgically enacts forms of democratic citizenship—first during Pinochet’s dictatorship as a hoped-for future and later, folÂlowing the democratic transition, as a present, if incomplete, reality. ReÂsponding to the vexed transitions to democracy, scholarship on Latin American theatre and performance has emphasized its resistance to the state. I complicate this formulation by examining how these perÂformances have been shaped by the political and institutional structures contingent to their producÂtion and by considering how critical poÂlitical performance is a category produced, in part, by the state. I therefore develop a model that allows for a more nuanced understanding of the performing arts to poliÂtics—one that accounts for an interdependÂent, sometimes paradoxical, and often mutuÂally constitutive dynamic
A Geoarcheological Survey of the Proposed Plainview Hike and Bike Trail, Hale County, Texas
In March of 2005, the Texas Department of Transportation issued work authorization #575-01-SA005 to the Center for Archaeological Research (CAR) at the University of Texas at San Antonio to conduct a survey of areas affected by proposed improvements to the Plainview hike and bike trail in southern Plainview, Hale County, Texas. The survey was conduced under Texas Antiquities Permit #3707 between March 31 and April 7, 2005. Steve Tomka and Raymond Mauldin served as Principal Investigators.
Trail construction included 2.0 miles of additional construction and 1.3 miles of improvements to existing trails. The Right-of-Way is 50 feet and extends from one to three feet below ground surface. Archeological services included a pedestrian survey, excavation of fifty-five auger tests placed no more than 100 m apart, and twenty-one Gradall trenches. Two of these trenches exposed the stratigraphy of Running Water Draw near the Plainview Site, 41HA1. Bulk samples were collected for OSL dating, diatoms analysis, and lithologic analysis for further examination of the age and stratigraphic context of the Plainview Site, which is a State Archeological Landmark, a National Landmark, and a National Register of Historic Places property. Site 41HA12 was re-examined with 10 mechanical auger tests and 1 trench, which found only recent alluvial and cultural deposition. No additional archeological sites were recorded. This report includes descriptions of the fieldwork, results of the special analyses performed on bulk sediment samples collected, and a discussion of the geomorphology of Running Water Draw with specific focus on the results from trenches excavated near the Plainview Site.
The single artifact and all documents and photographs generated from this project are curated at the Center for Archaeological Research at The University of Texas at San Antonio
Psychometric Properties of the Family Caregiver Delirium Knowledge Questionnaire
A valid, reliable measure of family caregivers’ knowledge about delirium was not located in the literature; such an instrument is essential to assess learning needs and outcomes of education provided. The purpose of the current study was to (a) develop a family Caregiver Delirium Knowledge Questionnaire (CDKQ) based on the Symptom Interpretation Model; and (b) establish validity and reliability of the measure. The 19-item CDKQ was developed and administered to 164 family caregivers for community-dwelling older adults. Descriptive statistics were examined for all variables. Psychometric testing included confirmatory factor analysis, item-to-total correlations, and internal consistency reliability. A three-factor model provided the best fit for the data. The findings support initial validity and reliability of the CDKQ with family caregivers. Although the CDKQ was developed for use with family caregivers, it has potential for use with other caregivers, such as home health aides
Recommended from our members
Validation of self-reported weights and heights in the avoiding diabetes after pregnancy trial (ADAPT)
Background: Randomized controlled trials that test the effectiveness of mobile health-based weight loss programs are attractive to participants, funders, and researchers because of the low implementation cost, minimal participant burden, and the ability to recruit participants from longer distances. Collecting weight data from geographically dispersed participants is a challenge. Relying on participant self-report is one approach to data collection, but epidemiologic studies indicate that self-reported anthropometric data may be inaccurate. Methods: We provided women enrolled in a randomized controlled trial (RCT) of postpartum weight loss after gestational diabetes with a digital scale and training to collect and report weight via a web-based survey. To validate self-reported weights and heights, we visited 30 randomly selected women in their homes, with a reference scale and stadiometer, a mean of 34 days after the self-report. We ran linear regression models to identify characteristics that were associated with underreporting or overreporting of anthropometric measures. Results: Of the 30 women we visited, 11 women (37%) were assigned to the weight loss intervention group and 19 women (63%) were in the control group. Mean age was 38.5 years (SD 4.5). The overall mean difference between participants’ self-reported weights and the weights obtained at their home visit was 0.70 kg (+1.92). Women assigned to the intervention group underreported their weight in comparison with the control group by 1.29 kg (95% CI −2.52, −0.06). The overall difference in collected to self-reported height was −0.56 cm (±1.91). No characteristics were associated with underreporting or overreporting of height. Conclusions: Our research suggests that by providing a digital scale and developing a weight collection protocol, researchers can train women to collect and record their own study weights with reasonable validity. To achieve the level of validity required for clinical trials, researchers should consider additional strategies to assure the validity of the data. Trial registration NCT01923350
Comparing cover crop research in farmer-led and researcher-led experiments in the Western Corn Belt
Cover crops can mitigate soil degradation and nutrient loss and can be used to achieve continuous living cover in cropping systems, although their adoption in the Western Corn Belt of the United States remains low. It is increasingly recognized that cover crop integration into corn (Zea mays L.)-based crop rotations is complex, requiring site and operation specific management. In this review, we compared on-farm, farmer-led field scale trials to researcher-led trials carried out in small plots on University of Nebraska-Lincoln experiment stations. Although there is a range of cover crop research conducted in the state, there is no synthesis of the scope and key results of such eorts. Common cover crop challenges and goals in the state are similar to those reported nationwide; challenges include adequate planting timing, associated costs, and weather, while a top goal of cover crop use is to improve soil health. Farmer-led trials most frequently compared a cover crop to a no-cover crop control, likely reflecting a desire to test a basic design determining site-specific performance. Both researcher-led and farmer-led trials included designs testing cash crop planting timing, while some portion of farmer-led trials tested cover crop seeding rates, which are directly related to reported cover crop challenges. Farmer-led trials were carried out on a greater variety of soils, including sandy soils, whereas sandy soils were absent from researcher-led trials. More than half of farmer- led experiments were conducted on fields with slopes of 6–17% while most researcher-led experiments were conducted on fields with slopes of \u3c1%. Mean cover crop biomass production was 600 kg/ha in farmer-led and 2,000 kg/ha in researcher-led trials. Crop yields were not significantly aected by cover crops in either farmer-led or researcher-led trials. Such comparisons demonstrate that in some instances, cover crop research is addressing challenges, and in some instances, it could be expanded. This synthesis expands our knowledge base in a way that can promote co-learning between dierent scales of experiments, and ultimately, reduce risks associated with cover crop management and further promote continuous living cover of agricultural landscapes
- …