Further caries decline in Swiss recruits from 1996 to 2006

Swiss army recruits (N = 606) from the army base at Thun were dentally examined with a standardized method in the year 2006. The results were compared with those of previous surveys (1985 and 1996). The mean DM6FT-value in the year 2006 was 3.11, whereas in 1996 it had been clearly higher (4.95). This corresponds to a caries decline of 37%. The observed caries decline can only partly be explained. Recruits, who were smokers, showed an increased caries experience. Recruits of the German-speaking part of Switzerland who had profited from oral health lessons by oral health instructors in Kindergarten and primary schools did not differ in caries experience from recruits of the French-speaking part of Switzerland

Weiterer Kariesrückgang bei Schweizer Rekruten von 1996 bis 2006

Rekruten der Rekrutenschule Thun (N = 606) wurden im Jahr 2006 mit einer standardisierten Methode zahnmedizinisch untersucht. Die Resultate wurden mit denjenigen aus früheren Erhebungen (1985 und 1996) verglichen. Der DM6FT-Wert betrug im Jahr 2006 im Durchschnitt 3,11; im Jahr 1996 lag er noch deutlich höher (4,95). Dies entspricht einem Kariesrückgang von 37%. Der beobachtete Kariesrückgang konnte nur zum Teil erklärt werden. Rekruten, die rauchten, zeigten einen erhöhten Kariesbefall. Rekruten aus der Deutschschweiz, die in Kindergarten und Primarschule von Schulzahnpflege- Instruktorinnen betreut worden waren, unterschieden sich im Kariesbefall nicht von den Rekruten aus der Romandie

Climate stories: enabling and sustaining arts interventions in climate science communication

This is the final version. Available from Copernicus Publications via the DOI in this record. Data availability. The research data used for this paper are not available in the public domain because of the ethical implications of making full transcripts available. The research was undertaken with a small sample of individuals from two institutions (University of Exeter and UK Met Office). The nature of the interview conversations held, which comprise the qualitative data in this paper, would enable individuals to be identified. Interviewees were specifically asked to discuss potentially sensitive issues related to their research training, experiences, emotions, feelings, and ethical positionality as part of the process of data collection. Because of this, publishing full interview transcripts would breach the ethical standard set for the research and approved by the Geography Ethics Committee at the University of Exeter, which stated that data would not be reported in a way that an individual could be identified. This was the basis for participants signing a consent form regarding how their data would be stored and used.The climate science community faces a major challenge with respect to communicating the risks associated with climate change within a heavily politicised landscape that is characterised by varying degrees of denial, scepticism, distrust in scientific enterprise, and an increased prevalence of misinformation (“fake news”). This issue is particularly significant given the reliance on conventional “deficit” communication approaches, which are based on the assumption that scientific information provision will necessarily lead to desired behavioural changes. Indeed, the constrained orthodoxy of scientific practices in seeking to maintain strict objectivity and political separation imposes very tangible limits on the potential effectiveness of climate scientists for communicating risk in many contemporary settings. To address these challenges, this paper uses insights from a collaboration between UK climate scientists and artist researchers to argue for a more creative and emotionally attentive approach to climate science engagement and advocacy. In so doing, the paper highlights innovative ways in which climate change communication can be reimagined through different art forms to enable complex concepts to become knowable. We suggest that in learning to express their work through forms of art, including print-making, theatre and performance, song-writing, and creative writing, researchers experienced not only a sense of liberation from the rigid communicative framework operating in their familiar scientific environment but also a growing self-confidence in their ability and willingness to engage in new ways of expressing their work. As such, we argue that scientific institutions and funding bodies should recognise the potential value of climate scientists engaging in advocacy through art–science collaborations and that these personal investments and contributions to science engagement by individuals should be rewarded and valued alongside conventional scientific outputs.Natural Environment Research Counci

Patient-reported outcomes in the aging population of adults with congenital heart disease: results from APPROACH-IS.

The congenital heart disease (CHD) population now comprises an increasing number of older persons in their 6th decade of life and beyond. We cross-sectionally evaluated patient-reported outcomes (PROs) in persons with CHD aged 60 years or older, and contrasted these with PROs of younger patients aged 40-59 years and 18-39 years. Adjusted for demographic and medical characteristics, patients ≥60 years had a lower Physical Component Summary, higher Mental Component Summary, and lower anxiety (Hospital Anxiety and Depression Scale-Anxiety) scores than patients in the two younger categories. For satisfaction with life, older persons had a higher score than patients aged 40-59 years. Registration: ClinicalTrials.gov NCT02150603

Quality of life in Maltese Adults with Congenital Heart Disease : a Second Look – An APPROACH-IS Substudy

Background A first quality of life (QOL) study among Maltese adults with congenital heart disease (ACHD) in 2016 found no significant differences when compared to the general population. The aims of the present study were to (1) compare QOL between Maltese and other European ACHD patients and (2) investigate medical predictors (i.e. number of surgical/non-surgical interventions, heart failure, arrhythmias, pacemaker/implantable cardioverter-defibrillator, cardiac hospitalisation during preceding year, follow-up frequency, other medical conditions, mood/anxiety/psychiatric disorders) of QOL in Maltese patients. Methods Data collected during \u201cAssessment of Patterns of Patient-Reported Outcomes in Adults with Congenital Heart disease\u2013International Study\u201d (APPROACH-IS) was used. QOL was measured using linear analog scale (LAS) and Satisfaction With Life Scale (SWLS). QOL in 109 Maltese and 1510 European participants was compared. Multivariable logistic regression was used to test the predictive value of medical factors on QOL in Maltese patients. Results There were no significant differences in QOL between the two cohorts [mean LAS Malta 80.51 (95% CI 77.96,83.07) vs. European 79.43 (95% CI 78.65,80.21) (p=0.776); mean SWLS Malta 26.00 (95% CI 24.94,27.06) vs. European 26.26 (95% CI 25.95,26.57) (p=0.288)] and no significant differences when cohorts were divided by gender and age. Only a mood/anxiety/other psychiatric disorder significantly predicted poorer QOL on both scales in Maltese patients (LAS ( f=-.389, p<0.001), SWLS ( f=-.352, p=0.001)). Conclusions Maltese ACHD patients have a good QOL comparable to that of European counterparts. Mood, anxiety and other psychiatric disorders can negatively impact Maltese patients\u2019 QOL. Better access to clinical psychology services should be ensured

Rationale, design and methodology of APPROACH-IS II: International study of patient-reported outcomes and frailty phenotyping in adults with congenital heart disease.

In recent years, patient-reported outcomes (PROs) have received increasing prominence in cardiovascular research and clinical care. An understanding of the variability and global experience of PROs in adults with congenital heart disease (CHD), however, is still lacking. Moreover, information on epidemiological characteristics and the frailty phenotype of older adults with CHD is minimal. The APPROACH-IS II study was established to address these knowledge gaps. This paper presents the design and methodology of APPROACH-IS II. APPROACH-IS II is a cross-sectional global multicentric study that includes Part 1 (assessing PROs) and Part 2 (investigating the frailty phenotype of older adults). With 53 participating centers, located in 32 countries across six continents, the aim is to enroll 8000 patients with CHD. In Part 1, self-report surveys are used to collect data on PROs (e.g., quality of life, perceived health, depressive symptoms, autonomy support), and explanatory variables (e.g., social support, stigma, illness identity, empowerment). In Part 2, the cognitive functioning and frailty phenotype of older adults are measured using validated assessments. APPROACH-IS II will generate a rich dataset representing the international experience of individuals in adult CHD care. The results of this project will provide a global view of PROs and the frailty phenotype of adults with CHD and will thereby address important knowledge gaps. Undoubtedly, the project will contribute to the overarching aim of improving optimal living and care provision for adults with CHD

The decrease of maximal oxygen consumption during hypoxia in man: a mirror image of the oxygen equilibrium curve.

1. Endurance athletes (E) undergo a marked reduction of arterial O2 saturation (Sa,O2) at maximal exercise in normoxia, which disappears when they breathe hyperoxic mixtures. In addition, at a given level of hypoxia, the drop in maximal O2 consumption (VO2,max) is positively related to the individual normoxic VO2,max. 2. These data suggest that the curve relating VO2,max to PI,O2 may be steeper and perhaps less curved in E than in sedentary subjects (S) with low VO2,max values because of the greater hypoxaemia in the latter, whence the hypotheses that (i) the relationship between VO2,max and PI,O2 may be set by the shape of the oxygen equilibrium curve; and (ii) the differences between E and S may be due to the different position on the oxygen equilibrium curve on which these subjects operate. These hypotheses have been tested by performing a systematic comparison of the VO2,max or Sa,O2 vs. PI,O2 relationships in E and S. 3. On ten subjects (five S and five E), VO2,max was measured by standard procedure during cycloergometric exercise. Sa,O2 was measured by finger-tip infrared oximetry. Arterialized blood PO2 (Pa,O2) and PCO2 (Pa,CO2) were determined in 80 microliters blood samples from an ear lobe. The subjects breathed ambient air or a N2-O2 mixture with an inspired O2 fraction (FI,O2) of 0.30, 0.18, 0.16, 0.13 and 0.11, respectively, VO2,max was normalized with respect to that obtained at the highest FI,O2. 4. The relationships between Sa,O2 or normalized VO2,max and FI,O2 (or PI,O2) had similar shapes, the data for E being systematically below and significantly different from those for S. Linear relationships between Sa,O2 and normalized VO2,max, statistically equal between E and S, were found. 5. We conclude that the relationships between either VO2,max or Sa,O2 and FI,O2 (or Pa,O2) may indeed be the mirror images of one another, implying a strict link between the decrease of VO2,max in hypoxia and the shape of the oxygen equilibrium curve, as hypothesized

Projekt "Weidekuh-Genetik": Produktion, Zusammenfassung und Perspektiven

Der Versuch hatte zum Ziel, die Schweizer Rassen Holstein, Fleckvieh und Brown Swiss mit derjenigen neuseeländischer Holstein- Friesian auf Vollweidebetrieben mit saisonaler Abkalbung Ende Winter zu vergleichen. Die zwei Holsteintypen wiesen die besseren Milchleistungen auf, die Schweizer Fleckvieh des Versuchs dagegen eine optimale Fruchtbarkeit. Die Schweizer Holstein ist auch in Low-Input-Systemen eine effiziente Milchkuh, sie müsste jedoch für Blockabkalbung bessere Fruchtbarkeitsleistungen aufweisen, obwohl unsere Modellrechnungen allerdings darauf hin deuten, dass die Milchproduktion einen grösseren Einfluss als die Fruchtbarkeit oder die Fleischleistung hat, was hier den zwei milchbetonteren Holsteintypen einen wirtschaftlichen Vorteil verschafft. Die erhobenen Datensätze für diese spezifische Systeme müssen jedoch vervollständigt werden. Die Wahl von Produktionssystemen und effizienten Tieren für diese Systeme bleibt ein grosses und sich weiter entwickelndes Forschungsfeld. Die Effizienz eines Tieres hängt vom System ab und die Definition t der «Ressourcen- Effizienz» selbst entwickelt sich mit den wissenschaftlichen Fortschritten in der Tierproduktion, der menschlichen Ernährung, der Klimatologie und Ökologie weiter