Nondestructive testing techniques used in analysis of honeycomb structure bond strength

DOT /Driver-Displacement Oriented Transducer/, applicable to both lap shear type application and honeycomb sandwich structures, measures the displacement of the honeycomb composite face sheet. It incorporates an electromagnetic driver and a displacement measuring system into a single unit to provide noncontact bond strength measurements

Fatigue testing a plurality of test specimens and method

Described is a fatigue testing apparatus for simultaneously subjecting a plurality of material test specimens to cyclical tension loading to determine the fatigue strength of the material. The fatigue testing apparatus includes a pulling head having cylinders defined therein which carry reciprocating pistons. The reciprocation of the pistons is determined by cyclical supplies of pressurized fluid to the cylinders. Piston rods extend from the pistons through the pulling head and are attachable to one end of the test specimens, the other end of the test specimens being attachable to a fixed base, causing test specimens attached between the piston rods and the base to be subjected to cyclical tension loading. Because all the cylinders share a common pressurized fluid supply, the breaking of a test specimen does not substantially affect the pressure of the fluid supplied to the other cylinders nor the tension applied to the other test specimens

Potential Risks Associated With The Legalization Of Exotic Predators Such As The Ferret (\u3ci\u3eMustela Putorius Furo\u3c/i\u3e) In California

The interest in possessing ferrets as pets has given rise to controversy between the rights of the individual to own the pet of their choice and the concerns for protection of wildlife in California. An overview of the legislative history in California illustrates the state\u27s attempts at protecting native wildlife species from exotic wild birds and animals. Concerns as to the potential threats associated with the legalization of ferrets in California are warranted in light of the wildlife damage resulting from the deliberate introduction of ferrets in New Zealand and the non-native red fox in California. A framework to assess risks involved with introducing non-native species that may impact native wildlife is needed

Modeling the magnetic pickup of an electric guitar

The magnetic pickup of an electric guitar uses electromagnetic induction to convert the motion of a ferromagnetic guitar string into an electrical signal. Although the magnetic pickup is often cited as an everyday application of Faraday\u27s law, few sources mention the distortion that the pickup generates when converting string motion into an electric signal, and even fewer attempt to analyze and explain this distortion. By modeling the magnet and ferromagnetic wire as surfaces with magnetic charge, an intuitive model that accurately predicts the output of a magnetic guitar pickup can be constructed. Moreimportantly, this model can be understood and manipulated by students at the undergraduate level and provides an excellent learning tool due to its straightforward mathematics and intuitive algorithm. Experiments show that it predicts the change in a magnetic field due to the presence of a ferromagnetic wire with a high degree of accuracy

Metallic Rotor Sizing and Performance Model for Flywheel Systems

The NASA Glenn Research Center (GRC) is developing flywheel system requirements and designs for terrestrial and spacecraft applications. Several generations of flywheels have been designed and tested at GRC using in-house expertise in motors, magnetic bearings, controls, materials and power electronics. The maturation of a flywheel system from the concept phase to the preliminary design phase is accompanied by maturation of the Integrated Systems Performance model, where estimating relationships are replaced by physics based analytical techniques. The modeling can incorporate results from engineering model testing and emerging detail from the design process

Direct oral anticoagulants‐Remove versus Taipan snake venom time for detection of a lupus anticoagulant in patients taking oral direct factor Xa inhibitors

Background: The optimal method of detecting a lupus anticoagulant (LA) for patients taking direct factor Xa inhibitor (DFXaI) direct oral anticoagulants (DOACs) remains controversial. Methods include charcoal adsorption of the DOACs to allow testing with the activated partial thromboplastin time (APTT) and dilute Russell viper venom time (dRVVT), or use of the DFXaI‐insensitive Taipan snake venom time (TSVT) and Ecarin time (ET) assays on neat plasma. Objectives: The objective was to compare the utility of APTT and dRVVT analysis following DOAC Remove against TSVT/ET on untreated plasma for LA detection in spiked plasmas and routine clinical samples for patients on DFXaIs. Patients/methods: Various LA‐negative and LA‐positive samples were assayed by APTT, dRVVT, and TSVT/ET, and then separately spiked with rivaroxaban, apixaban, and edoxaban calibrators to a concentration of ~190 ng/ml and the assays repeated on spiked plasma before and after DOAC Remove treatment. Testing of 284 consecutive samples from DFXaI‐anticoagulated patients by APTT/dRVVT and TSVT/ET before and after DOAC Remove treatment was undertaken. Results: In the spiking model, we found that both TSVT/ET and DOAC Remove strategies generally distinguished LA‐negative and LA‐positive samples, but some false‐positive LA results occurred. In the investigation of 284 consecutive patient samples on DFXaIs, the percentage agreement for LA detection in neat samples tested by TSVT/ET versus APTT and dRVVT after DOAC Remove treatment was 90% (Cohen kappa 0.12). Conclusion: Our data highlight uncertainty and disagreement for testing LA in patients on DFXaI. Further studies are required

The Optimal Single Copy Measurement for the Hidden Subgroup Problem

The optimization of measurements for the state distinction problem has recently been applied to the theory of quantum algorithms with considerable successes, including efficient new quantum algorithms for the non-abelian hidden subgroup problem. Previous work has identified the optimal single copy measurement for the hidden subgroup problem over abelian groups as well as for the non-abelian problem in the setting where the subgroups are restricted to be all conjugate to each other. Here we describe the optimal single copy measurement for the hidden subgroup problem when all of the subgroups of the group are given with equal a priori probability. The optimal measurement is seen to be a hybrid of the two previously discovered single copy optimal measurements for the hidden subgroup problem.Comment: 8 pages. Error in main proof fixe

Continuity properties of measurable group cohomology

A version of group cohomology for locally compact groups and Polish modules has previously been developed using a bar resolution restricted to measurable cochains. That theory was shown to enjoy analogs of most of the standard algebraic properties of group cohomology, but various analytic features of those cohomology groups were only partially understood. This paper re-examines some of those issues. At its heart is a simple dimension-shifting argument which enables one to `regularize' measurable cocycles, leading to some simplifications in the description of the cohomology groups. A range of consequences are then derived from this argument. First, we prove that for target modules that are Fr\'echet spaces, the cohomology groups agree with those defined using continuous cocycles, and hence they vanish in positive degrees when the acting group is compact. Using this, we then show that for Fr\'echet, discrete or toral modules the cohomology groups are continuous under forming inverse limits of compact base groups, and also under forming direct limits of discrete target modules. Lastly, these results together enable us to establish various circumstances under which the measurable-cochains cohomology groups coincide with others defined using sheaves on a semi-simplicial space associated to the underlying group, or sheaves on a classifying space for that group. We also prove in some cases that the natural quotient topologies on the measurable-cochains cohomology groups are Hausdorff.Comment: 52 pages. [Nov 22, 2011:] Major re-write with Calvin C. Moore as new co-author. Results from previous version strengthened and several new results added. [Nov 25, 2012:] Final version now available at springerlink.co

Placental contribution to the origins of sexual dimorphism in health and diseases: sex chromosomes and epigenetics

Sex differences occur in most non-communicable diseases, including metabolic diseases, hypertension, cardiovascular disease, psychiatric and neurological disorders and cancer. In many cases, the susceptibility to these diseases begins early in development. The observed differences between the sexes may result from genetic and hormonal differences and from differences in responses to and interactions with environmental factors, including infection, diet, drugs and stress. The placenta plays a key role in fetal growth and development and, as such, affects the fetal programming underlying subsequent adult health and accounts, in part for the developmental origin of health and disease (DOHaD). There is accumulating evidence to demonstrate the sex-specific relationships between diverse environmental influences on placental functions and the risk of disease later in life. As one of the few tissues easily collectable in humans, this organ may therefore be seen as an ideal system for studying how male and female placenta sense nutritional and other stresses, such as endocrine disruptors. Sex-specific regulatory pathways controlling sexually dimorphic characteristics in the various organs and the consequences of lifelong differences in sex hormone expression largely account for such responses. However, sex-specific changes in epigenetic marks are generated early after fertilization, thus before adrenal and gonad differentiation in the absence of sex hormones and in response to environmental conditions. Given the abundance of X-linked genes involved in placentogenesis, and the early unequal gene expression by the sex chromosomes between males and females, the role of X- and Y-chromosome-linked genes, and especially those involved in the peculiar placenta-specific epigenetics processes, giving rise to the unusual placenta epigenetic landscapes deserve particular attention. However, even with recent developments in this field, we still know little about the mechanisms underlying the early sex-specific epigenetic marks resulting in sex-biased gene expression of pathways and networks. As a critical messenger between the maternal environment and the fetus, the placenta may play a key role not only in buffering environmental effects transmitted by the mother but also in expressing and modulating effects due to preconceptional exposure of both the mother and the father to stressful conditions

Tidal stirring and the origin of dwarf spheroidals in the Local Group

N-Body/SPH simulations are used to study the evolution of dwarf irregular galaxies (dIrrs) entering the dark matter halo of the Milky Way or M31 on plunging orbits. We propose a new dynamical mechanism driving the evolution of gas rich, rotationally supported dIrrs, mostly found at the outskirts of the Local Group (LG), into gas free, pressure supported dwarf spheroidals (dSphs) or dwarf ellipticals (dEs), observed to cluster around the two giant spirals. The initial model galaxies are exponential disks embedded in massive dark matter halos and reproduce nearby dIrrs. Repeated tidal shocks at the pericenter of their orbit partially strip their halo and disk and trigger dynamical instabilities that dramatically reshape their stellar component. After only 2-3 orbits low surface brightness (LSB) dIrrs are transformed into dSphs, while high surface brightness (HSB) dIrrs evolve into dEs. This evolutionary mechanism naturally leads to the morphology-density relation observed for LG dwarfs. Dwarfs surrounded by very dense dark matter halos, like the archetypical dIrr GR8, are turned into Draco or Ursa Minor, the faintest and most dark matter dominated among LG dSphs. If disks include a gaseous component, this is both tidally stripped and consumed in periodic bursts of star formation. The resulting star formation histories are in good qualitative agreement with those derived using HST color-magnitude diagrams for local dSphs.Comment: 5 pages, 5 figures, to appear on ApJL. Simulation images and movies can be found at the Local Group web page at http://pcblu.uni.mi.astro.it/~lucio/LG/LG.htm