Fatigue performance of thermally cut bolt holes in structural steel S460M

Current fatigue codes only consider the fatigue performance of drilled and punched holes, limiting the use of thermal cutting processes to produce bolt holes. This paper studies the fatigue performance of structural steel S460M plates containing thermally cut bolt holes. The research covers three thermal cutting methods: the traditional one (oxy-fuel cutting) and two more modern processes (plasma and laser cutting). Specimen geometry is defined by a rectangular cross section with a cut hole in the middle. All the specimens were conducted to failure by applying fatigue cycles, the stress ratio (R) being 0.1. The corresponding S-N curve and fatigue limit were obtained for each cutting method. Fatigue results have been compared with previous researches on fatigue performance of drilled and punched holes, and with the predictions provided by current fatigue standards, analyzing the possibility to extrapolate their S-N curves, focused on drilled and punched holes, to thermally cut holes

Leukotriene antagonists as first-line or add-on asthma controller therapy

Most randomized trials of treatment for asthma study highly selected patients under idealized conditions. METHODS: We conducted two parallel, multicenter, pragmatic trials to evaluate the real-world effectiveness of a leukotriene-receptor antagonist (LTRA) as compared with either an inhaled glucocorticoid for first-line asthma-controller therapy or a long-acting beta(2)-agonist (LABA) as add-on therapy in patients already receiving inhaled glucocorticoid therapy. Eligible primary care patients 12 to 80 years of age had impaired asthma-related quality of life (Mini Asthma Quality of Life Questionnaire [MiniAQLQ] score =6) or inadequate asthma control (Asthma Control Questionnaire [ACQ] score =1). We randomly assigned patients to 2 years of open-label therapy, under the care of their usual physician, with LTRA (148 patients) or an inhaled glucocorticoid (158 patients) in the first-line controller therapy trial and LTRA (170 patients) or LABA (182 patients) added to an inhaled glucocorticoid in the add-on therapy trial. RESULTS: Mean MiniAQLQ scores increased by 0.8 to 1.0 point over a period of 2 years in both trials. At 2 months, differences in the MiniAQLQ scores between the two treatment groups met our definition of equivalence (95% confidence interval [CI] for an adjusted mean difference, -0.3 to 0.3). At 2 years, mean MiniAQLQ scores approached equivalence, with an adjusted mean difference between treatment groups of -0.11 (95% CI, -0.35 to 0.13) in the first-line controller therapy trial and of -0.11 (95% CI, -0.32 to 0.11) in the add-on therapy trial. Exacerbation rates and ACQ scores did not differ significantly between the two groups. CONCLUSIONS: Study results at 2 months suggest that LTRA was equivalent to an inhaled glucocorticoid as first-line controller therapy and to LABA as add-on therapy for diverse primary care patients. Equivalence was not proved at 2 years. The interpretation of results of pragmatic research may be limited by the crossover between treatment groups and lack of a placebo group

Multiscale characterisation of the electrical response of 3d printed carbon black polylactic acid

In this paper, the electrical response of a carbon black polylactic acid 3D printed polymer is characterised in detail by a combination of advanced experimental techniques at different scale lengths. The electrical properties as a function of the temperature become repeatable after the second heating cycle, exhibiting different trends as a function of the printing parameters. Joule heating and oven-heating techniques have been compared, showing the advantages of the Joule heating method to maintain electrical conductivity due to the lower thermal inertia. Small-Angle X-Ray Scattering has been employed to discern the underlying physics, showing the crucial role of crystallinity, filler dispersion and carbon black aggregates to form an effective segregated conductive network. This investigation provides guidelines to produce 3D-printed devices with a reliable electrical response and the governing equations to operate them with sufficient accuracy for engineering applications

Selected nucleon form factors and a composite scalar diquark

A covariant, composite scalar diquark, Fadde'ev amplitude model for the nucleon is used to calculate pseudoscalar, isoscalar- and isovector-vector, axial-vector and scalar nucleon form factors. The last yields the nucleon sigma-term and on-shell sigma-nucleon coupling. The calculated form factors are soft, and the couplings are generally in good agreement with experiment and other determinations. Elements in the dressed-quark-axial-vector vertex that are not constrained by the Ward-Takahashi identity contribute ~20% to the magnitude of g_A. The calculation of the nucleon sigma-term elucidates the only unambiguous means of extrapolating meson-nucleon couplings off the meson mass-shell.Comment: 12 pages, REVTEX, 5 figures, epsfi

Neutrinoless double-beta decay and seesaw mechanism

From the standard seesaw mechanism of neutrino mass generation, which is based on the assumption that the lepton number is violated at a large (~10exp(+15) GeV) scale, follows that the neutrinoless double-beta decay is ruled by the Majorana neutrino mass mechanism. Within this notion, for the inverted neutrino-mass hierarchy we derive allowed ranges of half-lives of the neutrinoless double-beta decay for nuclei of experimental interest with different sets of nuclear matrix elements. The present-day results of the calculation of the neutrinoless double-beta decay nuclear matrix elements are briefly discussed. We argue that if neutrinoless double-beta decay will be observed in future experiments sensitive to the effective Majorana mass in the inverted mass hierarchy region, a comparison of the derived ranges with measured half-lives will allow us to probe the standard seesaw mechanism assuming that future cosmological data will establish the sum of neutrino masses to be about 0.2 eV.Comment: Some changes in sections I, II, IV, and V; two new figures; additional reference

Survey of nucleon electromagnetic form factors

A dressed-quark core contribution to nucleon electromagnetic form factors is calculated. It is defined by the solution of a Poincare' covariant Faddeev equation in which dressed-quarks provide the elementary degree of freedom and correlations between them are expressed via diquarks. The nucleon-photon vertex involves a single parameter; i.e., a diquark charge radius. It is argued to be commensurate with the pion's charge radius. A comprehensive analysis and explanation of the form factors is built upon this foundation. A particular feature of the study is a separation of form factor contributions into those from different diagram types and correlation sectors, and subsequently a flavour separation for each of these. Amongst the extensive body of results that one could highlight are: r_1^{n,u}>r_1^{n,d}, owing to the presence of axial-vector quark-quark correlations; and for both the neutron and proton the ratio of Sachs electric and magnetic form factors possesses a zero.Comment: 43 pages, 17 figures, 12 tables, 5 appendice

Astroparticle Physics with a Customized Low-Background Broad Energy Germanium Detector

The MAJORANA Collaboration is building the MAJORANA DEMONSTRATOR, a 60 kg array of high purity germanium detectors housed in an ultra-low background shield at the Sanford Underground Laboratory in Lead, SD. The MAJORANA DEMONSTRATOR will search for neutrinoless double-beta decay of 76Ge while demonstrating the feasibility of a tonne-scale experiment. It may also carry out a dark matter search in the 1-10 GeV/c^2 mass range. We have found that customized Broad Energy Germanium (BEGe) detectors produced by Canberra have several desirable features for a neutrinoless double-beta decay experiment, including low electronic noise, excellent pulse shape analysis capabilities, and simple fabrication. We have deployed a customized BEGe, the MAJORANA Low-Background BEGe at Kimballton (MALBEK), in a low-background cryostat and shield at the Kimballton Underground Research Facility in Virginia. This paper will focus on the detector characteristics and measurements that can be performed with such a radiation detector in a low-background environment.Comment: Submitted to NIMA Proceedings, SORMA XII. 9 pages, 4 figure

New Cuoricino Results and Status of CUORE

CUORICINO is an array of 62 TeO2 bolometers with a total mass of 40.7 kg (11.2 kg of 130Te), operated at about 10 mK to search for ββ(0ν) of 130Te. The detectors are organized as a 14-story tower and intended as a slightly modified version of one of the 19 towers of the CUORE project, a proposed tightly packed array of 988 TeO2 bolometers (741 kg of total mass of TeO2) for ultralow-background searches on neutrinoless double-beta decay, cold dark matter, solar axions, and rare nuclear decays. Started in April 2003 at the Laboratori Nazionali del Gran Sasso (LNGS), CUORICINO data taking was stopped in November 2003 to repair the readout wiring system of the 62 bolometers. Restarted in spring 2004, CUORICINO is presently the most sensitive running experiment on neutrinoless double-beta decay. No evidence for ββ(0ν) decay has been found so far and a new lower limit, T 1 2/0ν ≥ 1.8 × 1024 yr (90% C.L.), is set, corresponding to 〈m ν〉 ≤ 0.2–1.1 eV, depending on the theoretical nuclear matrix elements used in the analysis. Detector performance, operational procedures, and background analysis results are reviewed. The expected performance and sensitivity of CUORE is also discussed